Compile Data Set for Download or QSAR

Found 87 hits with Last Name = 'martins' and Initial = 'ma'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50265993 (CHEMBL451230 | phenyl 4-(4,5-dihydro-1H-imidazol-2...) Show SMILES O=C(Oc1ccccc1)c1ccc(cc1)C1=NCCN1 |t:17| Show InChI InChI=1S/C16H14N2O2/c19-16(20-14-4-2-1-3-5-14)13-8-6-12(7-9-13)15-17-10-11-18-15/h1-9H,10-11H2,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50240366 (2-(naphthalen-2-yl)-4,5-dihydro-1H-imidazole | 2-N...) Show SMILES C1CN=C(N1)c1ccc2ccccc2c1 |c:2| Show InChI InChI=1S/C13H12N2/c1-2-4-11-9-12(6-5-10(11)3-1)13-14-7-8-15-13/h1-6,9H,7-8H2,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50086502 (2-BFi | 2-Benzofuran-2-yl-4,5-dihydro-1H-imidazole...) Show SMILES C1CN=C(N1)c1cc2ccccc2o1 |c:2| Show InChI InChI=1S/C11H10N2O/c1-2-4-9-8(3-1)7-10(14-9)11-12-5-6-13-11/h1-4,7H,5-6H2,(H,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	3.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50266030 (2-(2,4-dichlorophenyl)-4,5-dihydro-1H-imidazole | ...) Show SMILES Clc1ccc(C2=NCCN2)c(Cl)c1 |t:5| Show InChI InChI=1S/C9H8Cl2N2/c10-6-1-2-7(8(11)5-6)9-12-3-4-13-9/h1-2,5H,3-4H2,(H,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50240365 (2-(4,5-Dihydro-1H-imidazol-2-yl)-quinoline | 2-(4,...) Show SMILES C1CN=C(N1)c1ccc2ccccc2n1 |c:2| Show InChI InChI=1S/C12H11N3/c1-2-4-10-9(3-1)5-6-11(15-10)12-13-7-8-14-12/h1-6H,7-8H2,(H,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	4.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOA imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50240365 (2-(4,5-Dihydro-1H-imidazol-2-yl)-quinoline | 2-(4,...) Show SMILES C1CN=C(N1)c1ccc2ccccc2n1 |c:2| Show InChI InChI=1S/C12H11N3/c1-2-4-10-9(3-1)5-6-11(15-10)12-13-7-8-14-12/h1-6H,7-8H2,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	5.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50266028 (2-(4-chlorophenyl)-4,5-dihydro-1H-imidazole | CHEM...) Show SMILES Clc1ccc(cc1)C1=NCCN1 |t:8| Show InChI InChI=1S/C9H9ClN2/c10-8-3-1-7(2-4-8)9-11-5-6-12-9/h1-4H,5-6H2,(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	5.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50265993 (CHEMBL451230 | phenyl 4-(4,5-dihydro-1H-imidazol-2...) Show SMILES O=C(Oc1ccccc1)c1ccc(cc1)C1=NCCN1 |t:17| Show InChI InChI=1S/C16H14N2O2/c19-16(20-14-4-2-1-3-5-14)13-8-6-12(7-9-13)15-17-10-11-18-15/h1-9H,10-11H2,(H,17,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.28E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOA imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50240362 (2-p-tolyl-4,5-dihydro-1H-imidazole | CHEMBL269197) Show SMILES Cc1ccc(cc1)C1=NCCN1 |t:8| Show InChI InChI=1S/C10H12N2/c1-8-2-4-9(5-3-8)10-11-6-7-12-10/h2-5H,6-7H2,1H3,(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50265991 (2-(3,4-dimethoxyphenyl)-4,5-dihydro-1H-imidazole |...) Show SMILES COc1ccc(cc1OC)C1=NCCN1 |t:11| Show InChI InChI=1S/C11H14N2O2/c1-14-9-4-3-8(7-10(9)15-2)11-12-5-6-13-11/h3-4,7H,5-6H2,1-2H3,(H,12,13)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOA imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50240366 (2-(naphthalen-2-yl)-4,5-dihydro-1H-imidazole | 2-N...) Show SMILES C1CN=C(N1)c1ccc2ccccc2c1 |c:2| Show InChI InChI=1S/C13H12N2/c1-2-4-11-9-12(6-5-10(11)3-1)13-14-7-8-15-13/h1-6,9H,7-8H2,(H,14,15)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOA imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50240364 (2-(4-Methoxy-phenyl)-4,5-dihydro-1H-imidazole | 2-...) Show SMILES COc1ccc(cc1)C1=NCCN1 |t:9| Show InChI InChI=1S/C10H12N2O/c1-13-9-4-2-8(3-5-9)10-11-6-7-12-10/h2-5H,6-7H2,1H3,(H,11,12)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOA imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50266032 (2-(3-nitrophenyl)-4,5-dihydro-1H-imidazole | CHEMB...) Show SMILES [O-][N+](=O)c1cccc(c1)C1=NCCN1 |t:10| Show InChI InChI=1S/C9H9N3O2/c13-12(14)8-3-1-2-7(6-8)9-10-4-5-11-9/h1-3,6H,4-5H2,(H,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	1.93E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50240363 (2-Phenyl-4,5-dihydro-1H-imidazole | CHEMBL274548) Show SMILES C1CN=C(N1)c1ccccc1 |c:2| Show InChI InChI=1S/C9H10N2/c1-2-4-8(5-3-1)9-10-6-7-11-9/h1-5H,6-7H2,(H,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.13E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50266029 (2-(2-chlorophenyl)-4,5-dihydro-1H-imidazole | CHEM...) Show SMILES Clc1ccccc1C1=NCCN1 |t:8| Show InChI InChI=1S/C9H9ClN2/c10-8-4-2-1-3-7(8)9-11-5-6-12-9/h1-4H,5-6H2,(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.46E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50086502 (2-BFi | 2-Benzofuran-2-yl-4,5-dihydro-1H-imidazole...) Show SMILES C1CN=C(N1)c1cc2ccccc2o1 |c:2| Show InChI InChI=1S/C11H10N2O/c1-2-4-9-8(3-1)7-10(14-9)11-12-5-6-13-11/h1-4,7H,5-6H2,(H,12,13)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.49E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOA imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50240368 (2-(4,5-Dihydro-1H-imidazol-2-yl)-pyridine | 2-(4,5...) Show SMILES C1CN=C(N1)c1ccccn1 |c:2| Show InChI InChI=1S/C8H9N3/c1-2-4-9-7(3-1)8-10-5-6-11-8/h1-4H,5-6H2,(H,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	2.53E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50086502 (2-BFi | 2-Benzofuran-2-yl-4,5-dihydro-1H-imidazole...) Show SMILES C1CN=C(N1)c1cc2ccccc2o1 |c:2| Show InChI InChI=1S/C11H10N2O/c1-2-4-9-8(3-1)7-10(14-9)11-12-5-6-13-11/h1-4,7H,5-6H2,(H,12,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to human MAOB imidazoline binding site				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50266030 (2-(2,4-dichlorophenyl)-4,5-dihydro-1H-imidazole | ...) Show SMILES Clc1ccc(C2=NCCN2)c(Cl)c1 |t:5| Show InChI InChI=1S/C9H8Cl2N2/c10-6-1-2-7(8(11)5-6)9-12-3-4-13-9/h1-2,5H,3-4H2,(H,12,13)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.88E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOA imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50240363 (2-Phenyl-4,5-dihydro-1H-imidazole | CHEMBL274548) Show SMILES C1CN=C(N1)c1ccccc1 |c:2| Show InChI InChI=1S/C9H10N2/c1-2-4-8(5-3-1)9-10-6-7-11-9/h1-5H,6-7H2,(H,10,11)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.88E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOA imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50240364 (2-(4-Methoxy-phenyl)-4,5-dihydro-1H-imidazole | 2-...) Show SMILES COc1ccc(cc1)C1=NCCN1 |t:9| Show InChI InChI=1S/C10H12N2O/c1-13-9-4-2-8(3-5-9)10-11-6-7-12-10/h2-5H,6-7H2,1H3,(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.27E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50240362 (2-p-tolyl-4,5-dihydro-1H-imidazole | CHEMBL269197) Show SMILES Cc1ccc(cc1)C1=NCCN1 |t:8| Show InChI InChI=1S/C10H12N2/c1-8-2-4-9(5-3-8)10-11-6-7-12-10/h2-5H,6-7H2,1H3,(H,11,12)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.02E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOA imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50265992 (2-(3,4,5-trimethoxyphenyl)-4,5-dihydro-1H-imidazol...) Show SMILES COc1cc(cc(OC)c1OC)C1=NCCN1 |t:13| Show InChI InChI=1S/C12H16N2O3/c1-15-9-6-8(12-13-4-5-14-12)7-10(16-2)11(9)17-3/h6-7H,4-5H2,1-3H3,(H,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.14E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOA imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50266028 (2-(4-chlorophenyl)-4,5-dihydro-1H-imidazole | CHEM...) Show SMILES Clc1ccc(cc1)C1=NCCN1 |t:8| Show InChI InChI=1S/C9H9ClN2/c10-8-3-1-7(2-4-8)9-11-5-6-12-9/h1-4H,5-6H2,(H,11,12)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.66E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOA imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50266031 (2-(4-nitrophenyl)-4,5-dihydro-1H-imidazole | CHEMB...) Show SMILES [O-][N+](=O)c1ccc(cc1)C1=NCCN1 |t:10| Show InChI InChI=1S/C9H9N3O2/c13-12(14)8-3-1-7(2-4-8)9-10-5-6-11-9/h1-4H,5-6H2,(H,10,11)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	1.81E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOA imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50266031 (2-(4-nitrophenyl)-4,5-dihydro-1H-imidazole | CHEMB...) Show SMILES [O-][N+](=O)c1ccc(cc1)C1=NCCN1 |t:10| Show InChI InChI=1S/C9H9N3O2/c13-12(14)8-3-1-7(2-4-8)9-10-5-6-11-9/h1-4H,5-6H2,(H,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50240368 (2-(4,5-Dihydro-1H-imidazol-2-yl)-pyridine | 2-(4,5...) Show SMILES C1CN=C(N1)c1ccccn1 |c:2| Show InChI InChI=1S/C8H9N3/c1-2-4-9-7(3-1)8-10-5-6-11-8/h1-4H,5-6H2,(H,10,11)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOA imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50138501 (2-(furan-2-yl)-4,5-dihydro-1H-imidazole | 2-Furan-...) Show SMILES C1CN=C(N1)c1ccco1 |c:2| Show InChI InChI=1S/C7H8N2O/c1-2-6(10-5-1)7-8-3-4-9-7/h1-2,5H,3-4H2,(H,8,9)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50138501 (2-(furan-2-yl)-4,5-dihydro-1H-imidazole | 2-Furan-...) Show SMILES C1CN=C(N1)c1ccco1 |c:2| Show InChI InChI=1S/C7H8N2O/c1-2-6(10-5-1)7-8-3-4-9-7/h1-2,5H,3-4H2,(H,8,9)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOA imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50265991 (2-(3,4-dimethoxyphenyl)-4,5-dihydro-1H-imidazole |...) Show SMILES COc1ccc(cc1OC)C1=NCCN1 |t:11| Show InChI InChI=1S/C11H14N2O2/c1-14-9-4-3-8(7-10(9)15-2)11-12-5-6-13-11/h3-4,7H,5-6H2,1-2H3,(H,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50266032 (2-(3-nitrophenyl)-4,5-dihydro-1H-imidazole | CHEMB...) Show SMILES [O-][N+](=O)c1cccc(c1)C1=NCCN1 |t:10| Show InChI InChI=1S/C9H9N3O2/c13-12(14)8-3-1-2-7(6-8)9-10-4-5-11-9/h1-3,6H,4-5H2,(H,10,11)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOA imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50266029 (2-(2-chlorophenyl)-4,5-dihydro-1H-imidazole | CHEM...) Show SMILES Clc1ccccc1C1=NCCN1 |t:8| Show InChI InChI=1S/C9H9ClN2/c10-8-4-2-1-3-7(8)9-11-5-6-12-9/h1-4H,5-6H2,(H,11,12)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOA imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50265992 (2-(3,4,5-trimethoxyphenyl)-4,5-dihydro-1H-imidazol...) Show SMILES COc1cc(cc(OC)c1OC)C1=NCCN1 |t:13| Show InChI InChI=1S/C12H16N2O3/c1-15-9-6-8(12-13-4-5-14-12)7-10(16-2)11(9)17-3/h6-7H,4-5H2,1-3H3,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Binding affinity to MAOB imidazoline binding site in rat brain mitochondrial homogenate assessed as 4-hydroxyquinoline production by spectrophotometr...				Bioorg Med Chem Lett 19: 546-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.001 BindingDB Entry DOI: 10.7270/Q2251J2V
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM14774 (3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl...) Show SMILES FC(F)Oc1ccc(cc1OCC1CC1)C(=O)Nc1c(Cl)cncc1Cl Show InChI InChI=1S/C17H14Cl2F2N2O3/c18-11-6-22-7-12(19)15(11)23-16(24)10-3-4-13(26-17(20)21)14(5-10)25-8-9-1-2-9/h3-7,9,17H,1-2,8H2,(H,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDE4D using [3H]cAMP as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured af...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112492 BindingDB Entry DOI: 10.7270/Q2R21511
					More data for this Ligand-Target Pair				3D Structure (crystal)
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM14774 (3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl...) Show SMILES FC(F)Oc1ccc(cc1OCC1CC1)C(=O)Nc1c(Cl)cncc1Cl Show InChI InChI=1S/C17H14Cl2F2N2O3/c18-11-6-22-7-12(19)15(11)23-16(24)10-3-4-13(26-17(20)21)14(5-10)25-8-9-1-2-9/h3-7,9,17H,1-2,8H2,(H,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDE4B using [3H]cAMP as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured af...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112492 BindingDB Entry DOI: 10.7270/Q2R21511
					More data for this Ligand-Target Pair				3D Structure (crystal)
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM14774 (3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl...) Show SMILES FC(F)Oc1ccc(cc1OCC1CC1)C(=O)Nc1c(Cl)cncc1Cl Show InChI InChI=1S/C17H14Cl2F2N2O3/c18-11-6-22-7-12(19)15(11)23-16(24)10-3-4-13(26-17(20)21)14(5-10)25-8-9-1-2-9/h3-7,9,17H,1-2,8H2,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDE4A using [3H]cAMP as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured af...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112492 BindingDB Entry DOI: 10.7270/Q2R21511
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Homo sapiens (Human))	BDBM14774 (3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl...) Show SMILES FC(F)Oc1ccc(cc1OCC1CC1)C(=O)Nc1c(Cl)cncc1Cl Show InChI InChI=1S/C17H14Cl2F2N2O3/c18-11-6-22-7-12(19)15(11)23-16(24)10-3-4-13(26-17(20)21)14(5-10)25-8-9-1-2-9/h3-7,9,17H,1-2,8H2,(H,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDE4C using [3H]cAMP as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured af...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112492 BindingDB Entry DOI: 10.7270/Q2R21511
					More data for this Ligand-Target Pair				3D Structure (crystal)
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50555898 (CHEMBL3182164) Show SMILES C[C@@H](Oc1ccc(CNC(=O)c2cccnc2Oc2ccc3OCOc3c2)c(F)c1)C(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PDE4D (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112492 BindingDB Entry DOI: 10.7270/Q2R21511
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50346088 ((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...) Show SMILES COc1ccc(cc1OC1CCCC1)[C@]1(CC[C@@H](CC1)C(O)=O)C#N |r,wU:17.22,14.25,(4.79,2.97,;3.46,3.74,;2.12,2.97,;.79,3.74,;-.54,2.97,;-.54,1.43,;.79,.66,;2.12,1.43,;3.46,.66,;3.46,-.88,;4.7,-1.79,;4.23,-3.25,;2.69,-3.25,;2.21,-1.79,;-1.88,.66,;-3.42,.71,;-4.23,-.6,;-3.51,-1.96,;-1.97,-2.01,;-1.16,-.7,;-4.33,-3.26,;-3.6,-4.62,;-5.87,-3.21,;-1.77,2.19,;-1.66,3.73,)| Show InChI InChI=1S/C20H25NO4/c1-24-17-7-6-15(12-18(17)25-16-4-2-3-5-16)20(13-21)10-8-14(9-11-20)19(22)23/h6-7,12,14,16H,2-5,8-11H2,1H3,(H,22,23)/t14-,20-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PDE4D (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112492 BindingDB Entry DOI: 10.7270/Q2R21511
					More data for this Ligand-Target Pair				3D Structure (crystal)
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50396783 (CHEMBL2172710) Show SMILES COc1ccc(\C=N\N(C)C(=O)c2ccc(O)cc2)cc1OC Show InChI InChI=1S/C17H18N2O4/c1-19(17(21)13-5-7-14(20)8-6-13)18-11-12-4-9-15(22-2)16(10-12)23-3/h4-11,20H,1-3H3/b18-11+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D				J Med Chem 55: 7525-45 (2012) Article DOI: 10.1021/jm300514y BindingDB Entry DOI: 10.7270/Q2CC11TC
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50396783 (CHEMBL2172710) Show SMILES COc1ccc(\C=N\N(C)C(=O)c2ccc(O)cc2)cc1OC Show InChI InChI=1S/C17H18N2O4/c1-19(17(21)13-5-7-14(20)8-6-13)18-11-12-4-9-15(22-2)16(10-12)23-3/h4-11,20H,1-3H3/b18-11+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4B				J Med Chem 55: 7525-45 (2012) Article DOI: 10.1021/jm300514y BindingDB Entry DOI: 10.7270/Q2CC11TC
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50396784 (CHEMBL2172734) Show SMILES COc1ccc(cc1)C(=O)N(C)\N=C\c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C18H20N2O4/c1-20(18(21)14-6-8-15(22-2)9-7-14)19-12-13-5-10-16(23-3)17(11-13)24-4/h5-12H,1-4H3/b19-12+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4B				J Med Chem 55: 7525-45 (2012) Article DOI: 10.1021/jm300514y BindingDB Entry DOI: 10.7270/Q2CC11TC
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50396783 (CHEMBL2172710) Show SMILES COc1ccc(\C=N\N(C)C(=O)c2ccc(O)cc2)cc1OC Show InChI InChI=1S/C17H18N2O4/c1-19(17(21)13-5-7-14(20)8-6-13)18-11-12-4-9-15(22-2)16(10-12)23-3/h4-11,20H,1-3H3/b18-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4A				J Med Chem 55: 7525-45 (2012) Article DOI: 10.1021/jm300514y BindingDB Entry DOI: 10.7270/Q2CC11TC
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM14361 ((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...) Show SMILES COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1 Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PDE4A (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112492 BindingDB Entry DOI: 10.7270/Q2R21511
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50396784 (CHEMBL2172734) Show SMILES COc1ccc(cc1)C(=O)N(C)\N=C\c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C18H20N2O4/c1-20(18(21)14-6-8-15(22-2)9-7-14)19-12-13-5-10-16(23-3)17(11-13)24-4/h5-12H,1-4H3/b19-12+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D				J Med Chem 55: 7525-45 (2012) Article DOI: 10.1021/jm300514y BindingDB Entry DOI: 10.7270/Q2CC11TC
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM14361 ((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...) Show SMILES COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1 Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PDE4D (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112492 BindingDB Entry DOI: 10.7270/Q2R21511
					More data for this Ligand-Target Pair				3D Structure (crystal)
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50346088 ((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...) Show SMILES COc1ccc(cc1OC1CCCC1)[C@]1(CC[C@@H](CC1)C(O)=O)C#N |r,wU:17.22,14.25,(4.79,2.97,;3.46,3.74,;2.12,2.97,;.79,3.74,;-.54,2.97,;-.54,1.43,;.79,.66,;2.12,1.43,;3.46,.66,;3.46,-.88,;4.7,-1.79,;4.23,-3.25,;2.69,-3.25,;2.21,-1.79,;-1.88,.66,;-3.42,.71,;-4.23,-.6,;-3.51,-1.96,;-1.97,-2.01,;-1.16,-.7,;-4.33,-3.26,;-3.6,-4.62,;-5.87,-3.21,;-1.77,2.19,;-1.66,3.73,)| Show InChI InChI=1S/C20H25NO4/c1-24-17-7-6-15(12-18(17)25-16-4-2-3-5-16)20(13-21)10-8-14(9-11-20)19(22)23/h6-7,12,14,16H,2-5,8-11H2,1H3,(H,22,23)/t14-,20-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PDE4B (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112492 BindingDB Entry DOI: 10.7270/Q2R21511
					More data for this Ligand-Target Pair				3D Structure (crystal)
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50396782 (CHEMBL2172731) Show SMILES COc1ccc(\C=N\N(C)C(=O)c2ccccc2)cc1OC Show InChI InChI=1S/C17H18N2O3/c1-19(17(20)14-7-5-4-6-8-14)18-12-13-9-10-15(21-2)16(11-13)22-3/h4-12H,1-3H3/b18-12+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D				J Med Chem 55: 7525-45 (2012) Article DOI: 10.1021/jm300514y BindingDB Entry DOI: 10.7270/Q2CC11TC
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50396784 (CHEMBL2172734) Show SMILES COc1ccc(cc1)C(=O)N(C)\N=C\c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C18H20N2O4/c1-20(18(21)14-6-8-15(22-2)9-7-14)19-12-13-5-10-16(23-3)17(11-13)24-4/h5-12H,1-4H3/b19-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	159	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4A				J Med Chem 55: 7525-45 (2012) Article DOI: 10.1021/jm300514y BindingDB Entry DOI: 10.7270/Q2CC11TC
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50346088 ((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...) Show SMILES COc1ccc(cc1OC1CCCC1)[C@]1(CC[C@@H](CC1)C(O)=O)C#N |r,wU:17.22,14.25,(4.79,2.97,;3.46,3.74,;2.12,2.97,;.79,3.74,;-.54,2.97,;-.54,1.43,;.79,.66,;2.12,1.43,;3.46,.66,;3.46,-.88,;4.7,-1.79,;4.23,-3.25,;2.69,-3.25,;2.21,-1.79,;-1.88,.66,;-3.42,.71,;-4.23,-.6,;-3.51,-1.96,;-1.97,-2.01,;-1.16,-.7,;-4.33,-3.26,;-3.6,-4.62,;-5.87,-3.21,;-1.77,2.19,;-1.66,3.73,)| Show InChI InChI=1S/C20H25NO4/c1-24-17-7-6-15(12-18(17)25-16-4-2-3-5-16)20(13-21)10-8-14(9-11-20)19(22)23/h6-7,12,14,16H,2-5,8-11H2,1H3,(H,22,23)/t14-,20-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PDE4A (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112492 BindingDB Entry DOI: 10.7270/Q2R21511
					More data for this Ligand-Target Pair

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