Compile Data Set for Download or QSAR

Found 264 hits with Last Name = 'matralis' and Initial = 'an'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530642 (CHEMBL4531058) Show SMILES CN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)cc1 Show InChI InChI=1S/C29H32FN7S/c1-36-16-18-37(19-17-36)24-8-6-23(7-9-24)33-29-32-15-12-25(34-29)27-26(20-2-4-22(30)5-3-20)35-28(38-27)21-10-13-31-14-11-21/h2-9,12,15,21,31H,10-11,13-14,16-19H2,1H3,(H,32,33,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530642 (CHEMBL4531058) Show SMILES CN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)cc1 Show InChI InChI=1S/C29H32FN7S/c1-36-16-18-37(19-17-36)24-8-6-23(7-9-24)33-29-32-15-12-25(34-29)27-26(20-2-4-22(30)5-3-20)35-28(38-27)21-10-13-31-14-11-21/h2-9,12,15,21,31H,10-11,13-14,16-19H2,1H3,(H,32,33,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530662 (CHEMBL4459320) Show SMILES Nc1nc(c(s1)-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H22FN7S/c24-16-3-1-15(2-4-16)20-21(32-22(25)30-20)19-9-10-27-23(29-19)28-17-5-7-18(8-6-17)31-13-11-26-12-14-31/h1-10,26H,11-14H2,(H2,25,30)(H,27,28,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530662 (CHEMBL4459320) Show SMILES Nc1nc(c(s1)-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H22FN7S/c24-16-3-1-15(2-4-16)20-21(32-22(25)30-20)19-9-10-27-23(29-19)28-17-5-7-18(8-6-17)31-13-11-26-12-14-31/h1-10,26H,11-14H2,(H2,25,30)(H,27,28,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530649 (CHEMBL4451783) Show SMILES CC(=O)Nc1nc(c(s1)-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H24FN7OS/c1-16(34)29-25-32-22(17-2-4-18(26)5-3-17)23(35-25)21-10-11-28-24(31-21)30-19-6-8-20(9-7-19)33-14-12-27-13-15-33/h2-11,27H,12-15H2,1H3,(H,28,30,31)(H,29,32,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530639 (CHEMBL4461276) Show SMILES Cc1nc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)cc(C2CC2)c1F Show InChI InChI=1S/C27H26F2N6S/c1-15-23(29)20(16-2-3-16)14-22(32-15)34-27-31-13-10-21(33-27)25-24(17-4-6-19(28)7-5-17)35-26(36-25)18-8-11-30-12-9-18/h4-7,10,13-14,16,18,30H,2-3,8-9,11-12H2,1H3,(H,31,32,33,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530656 (CHEMBL4449947) Show SMILES CCc1cc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)nc(C)c1F Show InChI InChI=1S/C26H26F2N6S/c1-3-16-14-21(31-15(2)22(16)28)33-26-30-13-10-20(32-26)24-23(17-4-6-19(27)7-5-17)34-25(35-24)18-8-11-29-12-9-18/h4-7,10,13-14,18,29H,3,8-9,11-12H2,1-2H3,(H,30,31,32,33)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530653 (CHEMBL4469667) Show SMILES Cc1cc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)nn1C Show InChI InChI=1S/C23H24FN7S/c1-14-13-19(30-31(14)2)28-23-26-12-9-18(27-23)21-20(15-3-5-17(24)6-4-15)29-22(32-21)16-7-10-25-11-8-16/h3-6,9,12-13,16,25H,7-8,10-11H2,1-2H3,(H,26,27,28,30)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530639 (CHEMBL4461276) Show SMILES Cc1nc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)cc(C2CC2)c1F Show InChI InChI=1S/C27H26F2N6S/c1-15-23(29)20(16-2-3-16)14-22(32-15)34-27-31-13-10-21(33-27)25-24(17-4-6-19(28)7-5-17)35-26(36-25)18-8-11-30-12-9-18/h4-7,10,13-14,16,18,30H,2-3,8-9,11-12H2,1H3,(H,31,32,33,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530656 (CHEMBL4449947) Show SMILES CCc1cc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)nc(C)c1F Show InChI InChI=1S/C26H26F2N6S/c1-3-16-14-21(31-15(2)22(16)28)33-26-30-13-10-20(32-26)24-23(17-4-6-19(27)7-5-17)34-25(35-24)18-8-11-29-12-9-18/h4-7,10,13-14,18,29H,3,8-9,11-12H2,1-2H3,(H,30,31,32,33)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530663 (CHEMBL4532321) Show SMILES Fc1ccc(cc1)-c1nc(NS(=O)(=O)C2CCNCC2)sc1-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1 Show InChI InChI=1S/C28H31FN8O2S2/c29-20-3-1-19(2-4-20)25-26(40-28(35-25)36-41(38,39)23-9-12-30-13-10-23)24-11-14-32-27(34-24)33-21-5-7-22(8-6-21)37-17-15-31-16-18-37/h1-8,11,14,23,30-31H,9-10,12-13,15-18H2,(H,35,36)(H,32,33,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530663 (CHEMBL4532321) Show SMILES Fc1ccc(cc1)-c1nc(NS(=O)(=O)C2CCNCC2)sc1-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1 Show InChI InChI=1S/C28H31FN8O2S2/c29-20-3-1-19(2-4-20)25-26(40-28(35-25)36-41(38,39)23-9-12-30-13-10-23)24-11-14-32-27(34-24)33-21-5-7-22(8-6-21)37-17-15-31-16-18-37/h1-8,11,14,23,30-31H,9-10,12-13,15-18H2,(H,35,36)(H,32,33,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530649 (CHEMBL4451783) Show SMILES CC(=O)Nc1nc(c(s1)-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H24FN7OS/c1-16(34)29-25-32-22(17-2-4-18(26)5-3-17)23(35-25)21-10-11-28-24(31-21)30-19-6-8-20(9-7-19)33-14-12-27-13-15-33/h2-11,27H,12-15H2,1H3,(H,28,30,31)(H,29,32,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530653 (CHEMBL4469667) Show SMILES Cc1cc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)nn1C Show InChI InChI=1S/C23H24FN7S/c1-14-13-19(30-31(14)2)28-23-26-12-9-18(27-23)21-20(15-3-5-17(24)6-4-15)29-22(32-21)16-7-10-25-11-8-16/h3-6,9,12-13,16,25H,7-8,10-11H2,1-2H3,(H,26,27,28,30)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50467128 (CHEMBL4286841) Show SMILES CN1CCC(CC1)c1nc(c(s1)-c1ccnc(NCC2CC2)n1)-c1ccc(F)c(NS(C)(=O)=O)c1 Show InChI InChI=1S/C24H29FN6O2S2/c1-31-11-8-16(9-12-31)23-29-21(17-5-6-18(25)20(13-17)30-35(2,32)33)22(34-23)19-7-10-26-24(28-19)27-14-15-3-4-15/h5-7,10,13,15-16,30H,3-4,8-9,11-12,14H2,1-2H3,(H,26,27,28)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50467128 (CHEMBL4286841) Show SMILES CN1CCC(CC1)c1nc(c(s1)-c1ccnc(NCC2CC2)n1)-c1ccc(F)c(NS(C)(=O)=O)c1 Show InChI InChI=1S/C24H29FN6O2S2/c1-31-11-8-16(9-12-31)23-29-21(17-5-6-18(25)20(13-17)30-35(2,32)33)22(34-23)19-7-10-26-24(28-19)27-14-15-3-4-15/h5-7,10,13,15-16,30H,3-4,8-9,11-12,14H2,1-2H3,(H,26,27,28)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530660 (CHEMBL4455587) Show SMILES Fc1ccc(cc1)-c1nc(sc1-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1)N1CCCC1 Show InChI InChI=1S/C27H28FN7S/c28-20-5-3-19(4-6-20)24-25(36-27(33-24)35-15-1-2-16-35)23-11-12-30-26(32-23)31-21-7-9-22(10-8-21)34-17-13-29-14-18-34/h3-12,29H,1-2,13-18H2,(H,30,31,32)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50467123 (CHEMBL4288103) Show SMILES CN1CCC(CC1)c1nc(c(s1)-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1)-c1ccc(F)cc1 Show InChI InChI=1S/C29H32FN7S/c1-36-16-11-21(12-17-36)28-35-26(20-2-4-22(30)5-3-20)27(38-28)25-10-13-32-29(34-25)33-23-6-8-24(9-7-23)37-18-14-31-15-19-37/h2-10,13,21,31H,11-12,14-19H2,1H3,(H,32,33,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50467123 (CHEMBL4288103) Show SMILES CN1CCC(CC1)c1nc(c(s1)-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1)-c1ccc(F)cc1 Show InChI InChI=1S/C29H32FN7S/c1-36-16-11-21(12-17-36)28-35-26(20-2-4-22(30)5-3-20)27(38-28)25-10-13-32-29(34-25)33-23-6-8-24(9-7-23)37-18-14-31-15-19-37/h2-10,13,21,31H,11-12,14-19H2,1H3,(H,32,33,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530660 (CHEMBL4455587) Show SMILES Fc1ccc(cc1)-c1nc(sc1-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1)N1CCCC1 Show InChI InChI=1S/C27H28FN7S/c28-20-5-3-19(4-6-20)24-25(36-27(33-24)35-15-1-2-16-35)23-11-12-30-26(32-23)31-21-7-9-22(10-8-21)34-17-13-29-14-18-34/h3-12,29H,1-2,13-18H2,(H,30,31,32)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530661 (CHEMBL4593717) Show SMILES Cc1csc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)n1 Show InChI InChI=1S/C22H21FN6S2/c1-13-12-30-22(26-13)29-21-25-11-8-17(27-21)19-18(14-2-4-16(23)5-3-14)28-20(31-19)15-6-9-24-10-7-15/h2-5,8,11-12,15,24H,6-7,9-10H2,1H3,(H,25,26,27,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530661 (CHEMBL4593717) Show SMILES Cc1csc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)n1 Show InChI InChI=1S/C22H21FN6S2/c1-13-12-30-22(26-13)29-21-25-11-8-17(27-21)19-18(14-2-4-16(23)5-3-14)28-20(31-19)15-6-9-24-10-7-15/h2-5,8,11-12,15,24H,6-7,9-10H2,1H3,(H,25,26,27,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530652 (CHEMBL4572858) Show SMILES Cc1cc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)on1 Show InChI InChI=1S/C22H21FN6OS/c1-13-12-18(30-29-13)27-22-25-11-8-17(26-22)20-19(14-2-4-16(23)5-3-14)28-21(31-20)15-6-9-24-10-7-15/h2-5,8,11-12,15,24H,6-7,9-10H2,1H3,(H,25,26,27)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530652 (CHEMBL4572858) Show SMILES Cc1cc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)on1 Show InChI InChI=1S/C22H21FN6OS/c1-13-12-18(30-29-13)27-22-25-11-8-17(26-22)20-19(14-2-4-16(23)5-3-14)28-21(31-20)15-6-9-24-10-7-15/h2-5,8,11-12,15,24H,6-7,9-10H2,1H3,(H,25,26,27)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530647 (CHEMBL4585607) Show SMILES CN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2sc(N)nc2-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C24H24FN7S/c1-31-12-14-32(15-13-31)19-8-6-18(7-9-19)28-24-27-11-10-20(29-24)22-21(30-23(26)33-22)16-2-4-17(25)5-3-16/h2-11H,12-15H2,1H3,(H2,26,30)(H,27,28,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530647 (CHEMBL4585607) Show SMILES CN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2sc(N)nc2-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C24H24FN7S/c1-31-12-14-32(15-13-31)19-8-6-18(7-9-19)28-24-27-11-10-20(29-24)22-21(30-23(26)33-22)16-2-4-17(25)5-3-16/h2-11H,12-15H2,1H3,(H2,26,30)(H,27,28,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530646 (CHEMBL4531226) Show SMILES Fc1ccc(cc1)-c1nc(sc1-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1)N1CCOCC1 Show InChI InChI=1S/C27H28FN7OS/c28-20-3-1-19(2-4-20)24-25(37-27(33-24)35-15-17-36-18-16-35)23-9-10-30-26(32-23)31-21-5-7-22(8-6-21)34-13-11-29-12-14-34/h1-10,29H,11-18H2,(H,30,31,32)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530668 (CHEMBL4444451) Show SMILES Cc1nnc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)s1 Show InChI InChI=1S/C21H20FN7S2/c1-12-28-29-21(30-12)27-20-24-11-8-16(25-20)18-17(13-2-4-15(22)5-3-13)26-19(31-18)14-6-9-23-10-7-14/h2-5,8,11,14,23H,6-7,9-10H2,1H3,(H,24,25,27,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530668 (CHEMBL4444451) Show SMILES Cc1nnc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)s1 Show InChI InChI=1S/C21H20FN7S2/c1-12-28-29-21(30-12)27-20-24-11-8-16(25-20)18-17(13-2-4-15(22)5-3-13)26-19(31-18)14-6-9-23-10-7-14/h2-5,8,11,14,23H,6-7,9-10H2,1H3,(H,24,25,27,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530646 (CHEMBL4531226) Show SMILES Fc1ccc(cc1)-c1nc(sc1-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1)N1CCOCC1 Show InChI InChI=1S/C27H28FN7OS/c28-20-3-1-19(2-4-20)24-25(37-27(33-24)35-15-17-36-18-16-35)23-9-10-30-26(32-23)31-21-5-7-22(8-6-21)34-13-11-29-12-14-34/h1-10,29H,11-18H2,(H,30,31,32)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530651 (CHEMBL4566588) Show SMILES Fc1ccc(cc1)-c1nc(sc1-c1ccnc(Nc2nncs2)n1)C1CCNCC1 Show InChI InChI=1S/C20H18FN7S2/c21-14-3-1-12(2-4-14)16-17(30-18(26-16)13-5-8-22-9-6-13)15-7-10-23-19(25-15)27-20-28-24-11-29-20/h1-4,7,10-11,13,22H,5-6,8-9H2,(H,23,25,27,28)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530651 (CHEMBL4566588) Show SMILES Fc1ccc(cc1)-c1nc(sc1-c1ccnc(Nc2nncs2)n1)C1CCNCC1 Show InChI InChI=1S/C20H18FN7S2/c21-14-3-1-12(2-4-14)16-17(30-18(26-16)13-5-8-22-9-6-13)15-7-10-23-19(25-15)27-20-28-24-11-29-20/h1-4,7,10-11,13,22H,5-6,8-9H2,(H,23,25,27,28)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Homo sapiens (Human))	BDBM50098378 ((1-Hydroxy-1-phosphono-2-pyridin-2-yl-ethyl)-phosp...) Show SMILES OC(Cc1ccccn1)(P(O)(O)=O)P(O)(O)=O Show InChI InChI=1S/C7H11NO7P2/c9-7(16(10,11)12,17(13,14)15)5-6-3-1-2-4-8-6/h1-4,9H,5H2,(H2,10,11,12)(H2,13,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FPPS expressed in Escherichia coli BL21 (DE3) preincubated for 10 mins in presence compound relative to control				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01913 BindingDB Entry DOI: 10.7270/Q28K7F00
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530640 (CHEMBL4546641) Show SMILES Fc1ccc(cc1)-c1nc(sc1-c1ccnc(Nc2cccnn2)n1)C1CCNCC1 Show InChI InChI=1S/C22H20FN7S/c23-16-5-3-14(4-6-16)19-20(31-21(29-19)15-7-11-24-12-8-15)17-9-13-25-22(27-17)28-18-2-1-10-26-30-18/h1-6,9-10,13,15,24H,7-8,11-12H2,(H,25,27,28,30)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530640 (CHEMBL4546641) Show SMILES Fc1ccc(cc1)-c1nc(sc1-c1ccnc(Nc2cccnn2)n1)C1CCNCC1 Show InChI InChI=1S/C22H20FN7S/c23-16-5-3-14(4-6-16)19-20(31-21(29-19)15-7-11-24-12-8-15)17-9-13-25-22(27-17)28-18-2-1-10-26-30-18/h1-6,9-10,13,15,24H,7-8,11-12H2,(H,25,27,28,30)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530637 (CHEMBL4591417) Show SMILES Cc1cc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)ccn1 Show InChI InChI=1S/C24H23FN6S/c1-15-14-19(8-12-27-15)29-24-28-13-9-20(30-24)22-21(16-2-4-18(25)5-3-16)31-23(32-22)17-6-10-26-11-7-17/h2-5,8-9,12-14,17,26H,6-7,10-11H2,1H3,(H,27,28,29,30)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530637 (CHEMBL4591417) Show SMILES Cc1cc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)ccn1 Show InChI InChI=1S/C24H23FN6S/c1-15-14-19(8-12-27-15)29-24-28-13-9-20(30-24)22-21(16-2-4-18(25)5-3-16)31-23(32-22)17-6-10-26-11-7-17/h2-5,8-9,12-14,17,26H,6-7,10-11H2,1H3,(H,27,28,29,30)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530650 (CHEMBL4459919) Show SMILES CN1CCC(CC1)C(=O)Nc1nc(c(s1)-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1)-c1ccc(F)cc1 Show InChI InChI=1S/C30H33FN8OS/c1-38-16-11-21(12-17-38)28(40)37-30-36-26(20-2-4-22(31)5-3-20)27(41-30)25-10-13-33-29(35-25)34-23-6-8-24(9-7-23)39-18-14-32-15-19-39/h2-10,13,21,32H,11-12,14-19H2,1H3,(H,33,34,35)(H,36,37,40)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530650 (CHEMBL4459919) Show SMILES CN1CCC(CC1)C(=O)Nc1nc(c(s1)-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1)-c1ccc(F)cc1 Show InChI InChI=1S/C30H33FN8OS/c1-38-16-11-21(12-17-38)28(40)37-30-36-26(20-2-4-22(31)5-3-20)27(41-30)25-10-13-33-29(35-25)34-23-6-8-24(9-7-23)39-18-14-32-15-19-39/h2-10,13,21,32H,11-12,14-19H2,1H3,(H,33,34,35)(H,36,37,40)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530654 (CHEMBL4446015) Show SMILES Fc1ccc(cc1)-c1nc(sc1-c1ccnc(Nc2cnccn2)n1)C1CCNCC1 Show InChI InChI=1S/C22H20FN7S/c23-16-3-1-14(2-4-16)19-20(31-21(30-19)15-5-8-24-9-6-15)17-7-10-27-22(28-17)29-18-13-25-11-12-26-18/h1-4,7,10-13,15,24H,5-6,8-9H2,(H,26,27,28,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530654 (CHEMBL4446015) Show SMILES Fc1ccc(cc1)-c1nc(sc1-c1ccnc(Nc2cnccn2)n1)C1CCNCC1 Show InChI InChI=1S/C22H20FN7S/c23-16-3-1-14(2-4-16)19-20(31-21(30-19)15-5-8-24-9-6-15)17-7-10-27-22(28-17)29-18-13-25-11-12-26-18/h1-4,7,10-13,15,24H,5-6,8-9H2,(H,26,27,28,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530666 (CHEMBL4446024) Show SMILES Fc1ccc(cc1)-c1nc(sc1-c1ccnc(Nc2ccccn2)n1)C1CCNCC1 Show InChI InChI=1S/C23H21FN6S/c24-17-6-4-15(5-7-17)20-21(31-22(30-20)16-8-12-25-13-9-16)18-10-14-27-23(28-18)29-19-3-1-2-11-26-19/h1-7,10-11,14,16,25H,8-9,12-13H2,(H,26,27,28,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530666 (CHEMBL4446024) Show SMILES Fc1ccc(cc1)-c1nc(sc1-c1ccnc(Nc2ccccn2)n1)C1CCNCC1 Show InChI InChI=1S/C23H21FN6S/c24-17-6-4-15(5-7-17)20-21(31-22(30-20)16-8-12-25-13-9-16)18-10-14-27-23(28-18)29-19-3-1-2-11-26-19/h1-7,10-11,14,16,25H,8-9,12-13H2,(H,26,27,28,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530644 (CHEMBL4473609) Show SMILES Cc1cc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)cc(C)n1 Show InChI InChI=1S/C25H25FN6S/c1-15-13-20(14-16(2)29-15)30-25-28-12-9-21(31-25)23-22(17-3-5-19(26)6-4-17)32-24(33-23)18-7-10-27-11-8-18/h3-6,9,12-14,18,27H,7-8,10-11H2,1-2H3,(H,28,29,30,31)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530655 (CHEMBL4585479) Show SMILES Cc1nc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)ccc1F Show InChI InChI=1S/C24H22F2N6S/c1-14-18(26)6-7-20(29-14)31-24-28-13-10-19(30-24)22-21(15-2-4-17(25)5-3-15)32-23(33-22)16-8-11-27-12-9-16/h2-7,10,13,16,27H,8-9,11-12H2,1H3,(H,28,29,30,31)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530655 (CHEMBL4585479) Show SMILES Cc1nc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)ccc1F Show InChI InChI=1S/C24H22F2N6S/c1-14-18(26)6-7-20(29-14)31-24-28-13-10-19(30-24)22-21(15-2-4-17(25)5-3-15)32-23(33-22)16-8-11-27-12-9-16/h2-7,10,13,16,27H,8-9,11-12H2,1H3,(H,28,29,30,31)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530644 (CHEMBL4473609) Show SMILES Cc1cc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)cc(C)n1 Show InChI InChI=1S/C25H25FN6S/c1-15-13-20(14-16(2)29-15)30-25-28-12-9-21(31-25)23-22(17-3-5-19(26)6-4-17)32-24(33-23)18-7-10-27-11-8-18/h3-6,9,12-14,18,27H,7-8,10-11H2,1-2H3,(H,28,29,30,31)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530641 (CHEMBL4572065) Show SMILES Fc1ccc(cc1)-c1nc(sc1-c1ccnc(Nc2ccncn2)n1)C1CCNCC1 Show InChI InChI=1S/C22H20FN7S/c23-16-3-1-14(2-4-16)19-20(31-21(30-19)15-5-9-24-10-6-15)17-7-12-26-22(28-17)29-18-8-11-25-13-27-18/h1-4,7-8,11-13,15,24H,5-6,9-10H2,(H,25,26,27,28,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530641 (CHEMBL4572065) Show SMILES Fc1ccc(cc1)-c1nc(sc1-c1ccnc(Nc2ccncn2)n1)C1CCNCC1 Show InChI InChI=1S/C22H20FN7S/c23-16-3-1-14(2-4-16)19-20(31-21(30-19)15-5-9-24-10-6-15)17-7-12-26-22(28-17)29-18-8-11-25-13-27-18/h1-4,7-8,11-13,15,24H,5-6,9-10H2,(H,25,26,27,28,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530659 (CHEMBL4461850) Show SMILES Fc1ccc(cc1)-c1nc(sc1-c1ccnc(NCCN2CCSCC2)n1)C1CCNCC1 Show InChI InChI=1S/C24H29FN6S2/c25-19-3-1-17(2-4-19)21-22(33-23(30-21)18-5-8-26-9-6-18)20-7-10-27-24(29-20)28-11-12-31-13-15-32-16-14-31/h1-4,7,10,18,26H,5-6,8-9,11-16H2,(H,27,28,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair

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