Compile Data Set for Download or QSAR

Found 53 hits with Last Name = 'megat' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM14390 (5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...) Show SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 Show InChI InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of human platelets PDE5				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair				3D Structure (crystal)
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525387 (CHEMBL4441100) Show SMILES COc1ccc(CNc2nnc(-c3ccccc3)c3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C23H18F3N3O/c1-30-18-10-7-15(8-11-18)14-27-22-20-13-17(23(24,25)26)9-12-19(20)21(28-29-22)16-5-3-2-4-6-16/h2-13H,14H2,1H3,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525400 (CHEMBL4566048) Show SMILES COc1ccc(CNc2nnc(Cl)c3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C17H13ClF3N3O/c1-25-12-5-2-10(3-6-12)9-22-16-14-8-11(17(19,20)21)4-7-13(14)15(18)23-24-16/h2-8H,9H2,1H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM14363 (3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0...) Show SMILES CCCOc1ccccc1-c1nc2nn[nH]c2c(=O)[nH]1 Show InChI InChI=1S/C13H13N5O2/c1-2-7-20-9-6-4-3-5-8(9)11-14-12-10(13(19)15-11)16-18-17-12/h3-6H,2,7H2,1H3,(H2,14,15,16,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525355 (CHEMBL4462235) Show SMILES COc1ccc(CNc2nnc(N3CCCCC3)c3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C22H23F3N4O/c1-30-17-8-5-15(6-9-17)14-26-20-19-13-16(22(23,24)25)7-10-18(19)21(28-27-20)29-11-3-2-4-12-29/h5-10,13H,2-4,11-12,14H2,1H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525374 (CHEMBL4516439) Show SMILES COc1ccc(CNc2nnc(-c3ccccc3)c3ccccc23)cc1Cl Show InChI InChI=1S/C22H18ClN3O/c1-27-20-12-11-15(13-19(20)23)14-24-22-18-10-6-5-9-17(18)21(25-26-22)16-7-3-2-4-8-16/h2-13H,14H2,1H3,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50020874 ((3-Chloro-phenyl)-(4-phenyl-phthalazin-1-yl)-amine...) Show SMILES Clc1cccc(Nc2nnc(-c3ccccc3)c3ccccc23)c1 Show InChI InChI=1S/C20H14ClN3/c21-15-9-6-10-16(13-15)22-20-18-12-5-4-11-17(18)19(23-24-20)14-7-2-1-3-8-14/h1-13H,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of PDE5 (unknown origin) using 0.4 uM cGMP as substrate				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525399 (CHEMBL4441701) Show SMILES COc1ccc(CNC(=O)c2cc(ccc2NC2CCCCC2)C(F)(F)F)cc1 Show InChI InChI=1S/C22H25F3N2O2/c1-29-18-10-7-15(8-11-18)14-26-21(28)19-13-16(22(23,24)25)9-12-20(19)27-17-5-3-2-4-6-17/h7-13,17,27H,2-6,14H2,1H3,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525358 (CHEMBL4474310) Show SMILES COc1ccc(CNC(=O)c2cccc(c2)C(F)(F)F)cc1Cl Show InChI InChI=1S/C16H13ClF3NO2/c1-23-14-6-5-10(7-13(14)17)9-21-15(22)11-3-2-4-12(8-11)16(18,19)20/h2-8H,9H2,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525367 (CHEMBL4444580) Show SMILES COc1ccc(CNc2nn(C3CCCC3)c3ccc(cc23)C(F)(F)F)cc1Cl Show InChI InChI=1S/C21H21ClF3N3O/c1-29-19-9-6-13(10-17(19)22)12-26-20-16-11-14(21(23,24)25)7-8-18(16)28(27-20)15-4-2-3-5-15/h6-11,15H,2-5,12H2,1H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525388 (CHEMBL4451127) Show SMILES COc1ccc(CNc2nn(Cc3ccccc3)c3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C23H20F3N3O/c1-30-19-10-7-16(8-11-19)14-27-22-20-13-18(23(24,25)26)9-12-21(20)29(28-22)15-17-5-3-2-4-6-17/h2-13H,14-15H2,1H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525370 (CHEMBL4471948) Show SMILES FC(F)(F)c1ccc2n(nc(Nc3cccc(Cl)c3)c2c1)C1CCCC1 Show InChI InChI=1S/C19H17ClF3N3/c20-13-4-3-5-14(11-13)24-18-16-10-12(19(21,22)23)8-9-17(16)26(25-18)15-6-1-2-7-15/h3-5,8-11,15H,1-2,6-7H2,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525365 (CHEMBL4586506) Show SMILES COc1ccc(CNc2nn(-c3cccnc3)c3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C21H17F3N4O/c1-29-17-7-4-14(5-8-17)12-26-20-18-11-15(21(22,23)24)6-9-19(18)28(27-20)16-3-2-10-25-13-16/h2-11,13H,12H2,1H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525389 (CHEMBL4469331) Show SMILES COc1ccc(CNc2nn(C3CCCC3)c3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C21H22F3N3O/c1-28-17-9-6-14(7-10-17)13-25-20-18-12-15(21(22,23)24)8-11-19(18)27(26-20)16-4-2-3-5-16/h6-12,16H,2-5,13H2,1H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525386 (CHEMBL4451333) Show SMILES COc1ccc(cc1)-c1nnc(Nc2cccc(Cl)c2)c2ccccc12 Show InChI InChI=1S/C21H16ClN3O/c1-26-17-11-9-14(10-12-17)20-18-7-2-3-8-19(18)21(25-24-20)23-16-6-4-5-15(22)13-16/h2-13H,1H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM14390 (5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...) Show SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 Show InChI InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair				3D Structure (crystal)
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525366 (CHEMBL4473323) Show SMILES COc1ccc(CNc2nn(C3CCCCC3)c3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C22H24F3N3O/c1-29-18-10-7-15(8-11-18)14-26-21-19-13-16(22(23,24)25)9-12-20(19)28(27-21)17-5-3-2-4-6-17/h7-13,17H,2-6,14H2,1H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525360 (CHEMBL4565771) Show SMILES COc1ccc(CNc2nnc(N3CCC(O)CC3)c3ccccc23)cc1 Show InChI InChI=1S/C21H24N4O2/c1-27-17-8-6-15(7-9-17)14-22-20-18-4-2-3-5-19(18)21(24-23-20)25-12-10-16(26)11-13-25/h2-9,16,26H,10-14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525397 (CHEMBL4472638) Show SMILES COc1ccc(CNc2nn(C3CCCC3)c3ccc(cc23)C(F)(F)F)cc1F Show InChI InChI=1S/C21H21F4N3O/c1-29-19-9-6-13(10-17(19)22)12-26-20-16-11-14(21(23,24)25)7-8-18(16)28(27-20)15-4-2-3-5-15/h6-11,15H,2-5,12H2,1H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525390 (CHEMBL4463175) Show SMILES COc1ccc(CNc2nnc(N3CCCCC3)c3ccccc23)cc1 Show InChI InChI=1S/C21H24N4O/c1-26-17-11-9-16(10-12-17)15-22-20-18-7-3-4-8-19(18)21(24-23-20)25-13-5-2-6-14-25/h3-4,7-12H,2,5-6,13-15H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50020874 ((3-Chloro-phenyl)-(4-phenyl-phthalazin-1-yl)-amine...) Show SMILES Clc1cccc(Nc2nnc(-c3ccccc3)c3ccccc23)c1 Show InChI InChI=1S/C20H14ClN3/c21-15-9-6-10-16(13-15)22-20-18-12-5-4-11-17(18)19(23-24-20)14-7-2-1-3-8-14/h1-13H,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525359 (CHEMBL4459078) Show SMILES COc1ccc(CNc2nn(-c3ccccc3)c3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C22H18F3N3O/c1-29-18-10-7-15(8-11-18)14-26-21-19-13-16(22(23,24)25)9-12-20(19)28(27-21)17-5-3-2-4-6-17/h2-13H,14H2,1H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525375 (CHEMBL4436379) Show SMILES COc1ccc(CNc2nnc(-c3ccccc3)c3ccccc23)cc1 Show InChI InChI=1S/C22H19N3O/c1-26-18-13-11-16(12-14-18)15-23-22-20-10-6-5-9-19(20)21(24-25-22)17-7-3-2-4-8-17/h2-14H,15H2,1H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525384 (CHEMBL4464772) Show SMILES COc1cccc(CCNC(=O)c2cccc(c2)C(F)(F)F)c1 Show InChI InChI=1S/C17H16F3NO2/c1-23-15-7-2-4-12(10-15)8-9-21-16(22)13-5-3-6-14(11-13)17(18,19)20/h2-7,10-11H,8-9H2,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525383 (CHEMBL4475413) Show SMILES FC(F)(F)c1cccc(c1)C(=O)NCCc1ccc(Cl)cc1 Show InChI InChI=1S/C16H13ClF3NO/c17-14-6-4-11(5-7-14)8-9-21-15(22)12-2-1-3-13(10-12)16(18,19)20/h1-7,10H,8-9H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525382 (CHEMBL4561469) Show SMILES FC(F)(F)c1cccc(c1)C(=O)NCCc1ccccc1Cl Show InChI InChI=1S/C16H13ClF3NO/c17-14-7-2-1-4-11(14)8-9-21-15(22)12-5-3-6-13(10-12)16(18,19)20/h1-7,10H,8-9H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525381 (CHEMBL4534190) Show SMILES FC(F)(F)c1cccc(c1)C(=O)NCc1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C20H21F3N2O/c21-20(22,23)17-6-4-5-16(13-17)19(26)24-14-15-7-9-18(10-8-15)25-11-2-1-3-12-25/h4-10,13H,1-3,11-12,14H2,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525380 (CHEMBL4586085) Show SMILES Oc1ccc(CNC(=O)c2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C15H12F3NO2/c16-15(17,18)12-3-1-2-11(8-12)14(21)19-9-10-4-6-13(20)7-5-10/h1-8,20H,9H2,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525401 (CHEMBL2088641) Show SMILES FC(F)(F)c1cccc(c1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C16H14F3NO/c17-16(18,19)14-8-4-7-13(11-14)15(21)20-10-9-12-5-2-1-3-6-12/h1-8,11H,9-10H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525378 (CHEMBL4460054) Show SMILES Clc1ccc(cc1)-c1nnc(Nc2cccc(Cl)c2)c2ccccc12 Show InChI InChI=1S/C20H13Cl2N3/c21-14-10-8-13(9-11-14)19-17-6-1-2-7-18(17)20(25-24-19)23-16-5-3-4-15(22)12-16/h1-12H,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525377 (CHEMBL4555616) Show SMILES Clc1cccc(Nc2nnc(N3CCCCC3)c3ccccc23)c1 Show InChI InChI=1S/C19H19ClN4/c20-14-7-6-8-15(13-14)21-18-16-9-2-3-10-17(16)19(23-22-18)24-11-4-1-5-12-24/h2-3,6-10,13H,1,4-5,11-12H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525372 (CHEMBL4442370) Show SMILES COc1ccc(CCNc2nnc(-c3ccccc3)c3ccccc23)cc1 Show InChI InChI=1S/C23H21N3O/c1-27-19-13-11-17(12-14-19)15-16-24-23-21-10-6-5-9-20(21)22(25-26-23)18-7-3-2-4-8-18/h2-14H,15-16H2,1H3,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525371 (CHEMBL4448259) Show SMILES COc1ccc(CNc2nncc3ccccc23)cc1 Show InChI InChI=1S/C16H15N3O/c1-20-14-8-6-12(7-9-14)10-17-16-15-5-3-2-4-13(15)11-18-19-16/h2-9,11H,10H2,1H3,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525368 (CHEMBL4556746) Show SMILES COc1ccc(CNc2nn(C3CCCC3)c3ccccc23)cc1 Show InChI InChI=1S/C20H23N3O/c1-24-17-12-10-15(11-13-17)14-21-20-18-8-4-5-9-19(18)23(22-20)16-6-2-3-7-16/h4-5,8-13,16H,2-3,6-7,14H2,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525364 (CHEMBL4543329) Show SMILES COc1ccc(CNc2n[nH]c3ccccc23)cc1 Show InChI InChI=1S/C15H15N3O/c1-19-12-8-6-11(7-9-12)10-16-15-13-4-2-3-5-14(13)17-18-15/h2-9H,10H2,1H3,(H2,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525363 (CHEMBL4449264) Show SMILES COc1ccc(CNc2n[nH]c3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C16H14F3N3O/c1-23-12-5-2-10(3-6-12)9-20-15-13-8-11(16(17,18)19)4-7-14(13)21-22-15/h2-8H,9H2,1H3,(H2,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525379 (CHEMBL4524253) Show SMILES FC(F)(F)c1cccc(c1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C15H12F3NO/c16-15(17,18)13-8-4-7-12(9-13)14(20)19-10-11-5-2-1-3-6-11/h1-9H,10H2,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525398 (CHEMBL4589945) Show SMILES COc1ccccc1CNc1nnc(-c2ccccc2)c2ccccc12 Show InChI InChI=1S/C22H19N3O/c1-26-20-14-8-5-11-17(20)15-23-22-19-13-7-6-12-18(19)21(24-25-22)16-9-3-2-4-10-16/h2-14H,15H2,1H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525395 (CHEMBL4450870) Show SMILES COc1ccc(CCNC(=O)c2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C17H16F3NO2/c1-23-15-7-5-12(6-8-15)9-10-21-16(22)13-3-2-4-14(11-13)17(18,19)20/h2-8,11H,9-10H2,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525393 (CHEMBL4470619) Show SMILES FC(F)(F)c1cccc(c1)C(=O)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C15H11ClF3NO/c16-13-6-4-10(5-7-13)9-20-14(21)11-2-1-3-12(8-11)15(17,18)19/h1-8H,9H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525392 (CHEMBL4449807) Show SMILES Clc1cccc(Nc2nncc3ccccc23)c1 Show InChI InChI=1S/C14H10ClN3/c15-11-5-3-6-12(8-11)17-14-13-7-2-1-4-10(13)9-16-18-14/h1-9H,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525396 (CHEMBL4572825) Show SMILES COc1ccc(CNc2nn(C3CCCC3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C20H22ClN3O/c1-25-17-9-6-14(7-10-17)13-22-20-18-12-15(21)8-11-19(18)24(23-20)16-4-2-3-5-16/h6-12,16H,2-5,13H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525391 (CHEMBL4580388) Show SMILES C(Nc1nnc(-c2ccccc2)c2ccccc12)c1ccccc1 Show InChI InChI=1S/C21H17N3/c1-3-9-16(10-4-1)15-22-21-19-14-8-7-13-18(19)20(23-24-21)17-11-5-2-6-12-17/h1-14H,15H2,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525356 (CHEMBL4591523) Show SMILES COc1cccc(CNc2nnc(-c3ccccc3)c3ccccc23)c1 Show InChI InChI=1S/C22H19N3O/c1-26-18-11-7-8-16(14-18)15-23-22-20-13-6-5-12-19(20)21(24-25-22)17-9-3-2-4-10-17/h2-14H,15H2,1H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525373 (CHEMBL4473392) Show SMILES C(Nc1nnc(-c2ccccc2)c2ccccc12)c1ccc2OCOc2c1 Show InChI InChI=1S/C22H17N3O2/c1-2-6-16(7-3-1)21-17-8-4-5-9-18(17)22(25-24-21)23-13-15-10-11-19-20(12-15)27-14-26-19/h1-12H,13-14H2,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525369 (CHEMBL4437196) Show SMILES COc1ccc(CNc2nn(C)c3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C17H16F3N3O/c1-23-15-8-5-12(17(18,19)20)9-14(15)16(22-23)21-10-11-3-6-13(24-2)7-4-11/h3-9H,10H2,1-2H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525361 (CHEMBL4460956) Show SMILES COc1ccc(CNC(=O)c2cccc(c2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C15H14N2O4/c1-21-14-7-5-11(6-8-14)10-16-15(18)12-3-2-4-13(9-12)17(19)20/h2-9H,10H2,1H3,(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525394 (CHEMBL4453422) Show SMILES FC(F)(F)c1cccc(c1)C(=O)NCCc1cccc(Cl)c1 Show InChI InChI=1S/C16H13ClF3NO/c17-14-6-1-3-11(9-14)7-8-21-15(22)12-4-2-5-13(10-12)16(18,19)20/h1-6,9-10H,7-8H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525362 (CHEMBL4453732) Show SMILES COc1ccc(CNC(=O)c2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C16H14F3NO2/c1-22-14-7-5-11(6-8-14)10-20-15(21)12-3-2-4-13(9-12)16(17,18)19/h2-9H,10H2,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50525376 (CHEMBL4527792) Show SMILES Clc1ccc(Nc2nnc(-c3ccccc3)c3ccccc23)cc1 Show InChI InChI=1S/C20H14ClN3/c21-15-10-12-16(13-11-15)22-20-18-9-5-4-8-17(18)19(23-24-20)14-6-2-1-3-7-14/h1-13H,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026 BindingDB Entry DOI: 10.7270/Q2C250W8
					More data for this Ligand-Target Pair

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