Compile Data Set for Download or QSAR

Found 3979 hits with Last Name = 'minami' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198274 (US9216999, 81 | US9556187, Example 81) Show SMILES O[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:4.7,wD:1.0,(3.26,4.47,;2.17,3.38,;.68,3.78,;-.41,2.69,;-.01,1.2,;1.48,.81,;2.57,1.89,;-1.1,.12,;-2.63,.28,;-3.26,-1.13,;-2.11,-2.16,;-2.11,-3.7,;-.78,-4.47,;.55,-3.7,;2.02,-4.18,;2.92,-2.93,;2.02,-1.69,;.55,-2.16,;-.78,-1.39,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0840	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198643 (US9216999, 435b | US9556187, Example 435b) Show SMILES N#CC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:6.9,wD:3.2,(4.74,3.67,;3.26,4.07,;1.77,4.47,;.68,3.38,;-.81,3.78,;-1.9,2.69,;-1.5,1.2,;-.01,.81,;1.08,1.89,;-2.59,.12,;-4.12,.28,;-4.74,-1.13,;-3.6,-2.16,;-3.6,-3.7,;-2.27,-4.47,;-.93,-3.7,;.53,-4.18,;1.44,-2.93,;.53,-1.69,;-.93,-2.16,;-2.27,-1.39,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198643 (US9216999, 435b | US9556187, Example 435b) Show SMILES N#CC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:6.9,wD:3.2,(4.74,3.67,;3.26,4.07,;1.77,4.47,;.68,3.38,;-.81,3.78,;-1.9,2.69,;-1.5,1.2,;-.01,.81,;1.08,1.89,;-2.59,.12,;-4.12,.28,;-4.74,-1.13,;-3.6,-2.16,;-3.6,-3.7,;-2.27,-4.47,;-.93,-3.7,;.53,-4.18,;1.44,-2.93,;.53,-1.69,;-.93,-2.16,;-2.27,-1.39,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198634 (US9216999, 427 | US9556187, Example 427) Show SMILES CS(=O)(=O)NC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:9.12,wD:6.5,(5.29,3.67,;3.8,4.07,;4.2,5.56,;2.71,5.16,;2.71,2.98,;1.22,3.38,;.14,2.29,;-1.35,2.69,;-2.44,1.6,;-2.04,.12,;-.55,-.28,;.53,.81,;-3.13,-.97,;-4.66,-.81,;-5.29,-2.22,;-4.14,-3.25,;-4.14,-4.79,;-2.81,-5.56,;-1.48,-4.79,;-.01,-5.27,;.89,-4.02,;-.01,-2.77,;-1.48,-3.25,;-2.81,-2.48,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198634 (US9216999, 427 | US9556187, Example 427) Show SMILES CS(=O)(=O)NC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:9.12,wD:6.5,(5.29,3.67,;3.8,4.07,;4.2,5.56,;2.71,5.16,;2.71,2.98,;1.22,3.38,;.14,2.29,;-1.35,2.69,;-2.44,1.6,;-2.04,.12,;-.55,-.28,;.53,.81,;-3.13,-.97,;-4.66,-.81,;-5.29,-2.22,;-4.14,-3.25,;-4.14,-4.79,;-2.81,-5.56,;-1.48,-4.79,;-.01,-5.27,;.89,-4.02,;-.01,-2.77,;-1.48,-3.25,;-2.81,-2.48,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50285779 (CHEMBL4165205) Show SMILES COc1cc(cc(OC)c1C)[C@@H](O)[C@@H](CC1Cc2ccccc2C1)Cn1ccc(CCC(O)=O)c1 |r| Show InChI InChI=1S/C29H35NO5/c1-19-26(34-2)15-24(16-27(19)35-3)29(33)25(14-21-12-22-6-4-5-7-23(22)13-21)18-30-11-10-20(17-30)8-9-28(31)32/h4-7,10-11,15-17,21,25,29,33H,8-9,12-14,18H2,1-3H3,(H,31,32)/t25-,29+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
ONO Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at recombinant human LPA1 expressed in CHO cell membranes pretreated for 24 hrs prior to Fura-2-AM dye addition for 1 hr followed...				ACS Med Chem Lett 8: 1281-1286 (2017) Article DOI: 10.1021/acsmedchemlett.7b00383 BindingDB Entry DOI: 10.7270/Q2PG1V8Z
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50285779 (CHEMBL4165205) Show SMILES COc1cc(cc(OC)c1C)[C@@H](O)[C@@H](CC1Cc2ccccc2C1)Cn1ccc(CCC(O)=O)c1 |r| Show InChI InChI=1S/C29H35NO5/c1-19-26(34-2)15-24(16-27(19)35-3)29(33)25(14-21-12-22-6-4-5-7-23(22)13-21)18-30-11-10-20(17-30)8-9-28(31)32/h4-7,10-11,15-17,21,25,29,33H,8-9,12-14,18H2,1-3H3,(H,31,32)/t25-,29+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
ONO Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at recombinant human LPA1 expressed in CHO cell membranes pretreated for 24 hrs prior to Fura-2-AM dye addition for 1 hr followed...				ACS Med Chem Lett 8: 1281-1286 (2017) Article DOI: 10.1021/acsmedchemlett.7b00383 BindingDB Entry DOI: 10.7270/Q2PG1V8Z
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198268 (US9216999, 75 | US9556187, Example 75) Show SMILES ClC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:5.8,wD:2.1,(4,4.07,;2.51,4.47,;1.42,3.38,;-.06,3.78,;-1.15,2.69,;-.75,1.2,;.73,.81,;1.82,1.89,;-1.84,.12,;-3.37,.28,;-4,-1.13,;-2.86,-2.16,;-2.86,-3.7,;-1.52,-4.47,;-.19,-3.7,;1.28,-4.18,;2.18,-2.93,;1.28,-1.69,;-.19,-2.16,;-1.52,-1.39,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198268 (US9216999, 75 | US9556187, Example 75) Show SMILES ClC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:5.8,wD:2.1,(4,4.07,;2.51,4.47,;1.42,3.38,;-.06,3.78,;-1.15,2.69,;-.75,1.2,;.73,.81,;1.82,1.89,;-1.84,.12,;-3.37,.28,;-4,-1.13,;-2.86,-2.16,;-2.86,-3.7,;-1.52,-4.47,;-.19,-3.7,;1.28,-4.18,;2.18,-2.93,;1.28,-1.69,;-.19,-2.16,;-1.52,-1.39,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198587 (US9216999, 382b | US9556187, Example 382b) Show SMILES FC(F)(Br)CN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:9.12,wD:6.5,(5.29,3.67,;3.8,4.07,;3.4,5.56,;4.89,5.16,;2.71,2.98,;1.22,3.38,;.14,2.29,;-1.35,2.69,;-2.44,1.6,;-2.04,.12,;-.55,-.28,;.53,.81,;-3.13,-.97,;-4.66,-.81,;-5.29,-2.22,;-4.14,-3.25,;-4.14,-4.79,;-2.81,-5.56,;-1.48,-4.79,;-.01,-5.27,;.89,-4.02,;-.01,-2.77,;-1.48,-3.25,;-2.81,-2.48,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.310	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198587 (US9216999, 382b | US9556187, Example 382b) Show SMILES FC(F)(Br)CN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:9.12,wD:6.5,(5.29,3.67,;3.8,4.07,;3.4,5.56,;4.89,5.16,;2.71,2.98,;1.22,3.38,;.14,2.29,;-1.35,2.69,;-2.44,1.6,;-2.04,.12,;-.55,-.28,;.53,.81,;-3.13,-.97,;-4.66,-.81,;-5.29,-2.22,;-4.14,-3.25,;-4.14,-4.79,;-2.81,-5.56,;-1.48,-4.79,;-.01,-5.27,;.89,-4.02,;-.01,-2.77,;-1.48,-3.25,;-2.81,-2.48,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198245 (US9216999, 53 | US9556187, Example 53) Show SMILES Fc1cc(cc(F)c1CN1CCC(CC1)c1nnn2cnc3[nH]ccc3c12)C#N Show InChI InChI=1S/C20H17F2N7/c21-16-7-12(9-23)8-17(22)15(16)10-28-5-2-13(3-6-28)18-19-14-1-4-24-20(14)25-11-29(19)27-26-18/h1,4,7-8,11,13,24H,2-3,5-6,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.320	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198245 (US9216999, 53 | US9556187, Example 53) Show SMILES Fc1cc(cc(F)c1CN1CCC(CC1)c1nnn2cnc3[nH]ccc3c12)C#N Show InChI InChI=1S/C20H17F2N7/c21-16-7-12(9-23)8-17(22)15(16)10-28-5-2-13(3-6-28)18-19-14-1-4-24-20(14)25-11-29(19)27-26-18/h1,4,7-8,11,13,24H,2-3,5-6,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198572 (US9216999, 369) Show SMILES [N-]=[N]=NC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:7.10,wD:4.3,(5.09,5.36,;4,4.27,;2.91,3.18,;1.42,3.58,;.34,2.49,;-1.15,2.89,;-2.24,1.8,;-1.84,.31,;-.36,-.08,;.73,1.01,;-2.93,-.77,;-4.46,-.61,;-5.09,-2.02,;-3.95,-3.05,;-3.95,-4.59,;-2.61,-5.36,;-1.28,-4.59,;.19,-5.07,;1.09,-3.82,;.19,-2.57,;-1.28,-3.05,;-2.61,-2.28,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.330	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198269 (US9216999, 76 | US9556187, Example 76) Show SMILES SC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:5.8,wD:2.1,(4,4.07,;2.51,4.47,;1.42,3.38,;-.06,3.78,;-1.15,2.69,;-.75,1.2,;.73,.81,;1.82,1.89,;-1.84,.12,;-3.37,.28,;-4,-1.13,;-2.86,-2.16,;-2.86,-3.7,;-1.52,-4.47,;-.19,-3.7,;1.28,-4.18,;2.18,-2.93,;1.28,-1.69,;-.19,-2.16,;-1.52,-1.39,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM275285 (US9556187, Example 369) Show SMILES [N-]=[N+]=NC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:7.10,wD:4.3,(5.09,5.39,;4,4.3,;2.91,3.15,;1.42,3.55,;.34,2.46,;-1.15,2.86,;-2.24,1.77,;-1.84,.28,;-.36,-.12,;.73,.97,;-2.93,-.81,;-4.46,-.64,;-5.09,-2.05,;-3.95,-3.08,;-3.95,-4.62,;-2.61,-5.39,;-1.28,-4.62,;.19,-5.1,;1.09,-3.85,;.19,-2.61,;-1.28,-3.08,;-2.61,-2.31,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198269 (US9216999, 76 | US9556187, Example 76) Show SMILES SC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:5.8,wD:2.1,(4,4.07,;2.51,4.47,;1.42,3.38,;-.06,3.78,;-1.15,2.69,;-.75,1.2,;.73,.81,;1.82,1.89,;-1.84,.12,;-3.37,.28,;-4,-1.13,;-2.86,-2.16,;-2.86,-3.7,;-1.52,-4.47,;-.19,-3.7,;1.28,-4.18,;2.18,-2.93,;1.28,-1.69,;-.19,-2.16,;-1.52,-1.39,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.330	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM411421 (US10385052, Example 2) Show SMILES FC(F)(F)CCOCC1CCC(CC1)[C@H]1C2C(C=Nc3[nH]ccc23)C(=O)NC1=O |r,wU:14.14,c:18,(6.58,2.18,;7.92,2.95,;9.25,2.18,;7.92,1.41,;7.92,4.49,;6.58,5.26,;5.25,4.49,;4,5.39,;2.67,4.62,;2.67,3.08,;1.33,2.31,;0,3.08,;0,4.62,;1.33,5.39,;-1.33,2.31,;-1.33,.77,;-2.67,0,;-2.67,-1.54,;-1.33,-2.31,;0,-1.54,;1.46,-2.02,;2.37,-.77,;1.47,.48,;0,0,;-4,.77,;-5.33,0,;-4,2.31,;-2.67,3.08,;-2.67,4.62,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
Nissan Chemical Corporation US Patent					Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...				US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198267 (US9216999, 74 | US9556187, Example 74) Show SMILES BrC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:5.8,wD:2.1,(4,4.07,;2.51,4.47,;1.42,3.38,;-.06,3.78,;-1.15,2.69,;-.75,1.2,;.73,.81,;1.82,1.89,;-1.84,.12,;-3.37,.28,;-4,-1.13,;-2.86,-2.16,;-2.86,-3.7,;-1.52,-4.47,;-.19,-3.7,;1.28,-4.18,;2.18,-2.93,;1.28,-1.69,;-.19,-2.16,;-1.52,-1.39,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198272 (US9216999, 79 | US9556187, Example 79) Show SMILES FC(F)[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:6.9,wD:3.2,(4,3.33,;2.51,3.73,;2.11,5.21,;1.42,2.64,;-.06,3.04,;-1.15,1.95,;-.75,.46,;.73,.06,;1.82,1.15,;-1.84,-.63,;-3.37,-.47,;-4,-1.87,;-2.86,-2.9,;-2.86,-4.44,;-1.52,-5.21,;-.19,-4.44,;1.28,-4.92,;2.18,-3.67,;1.28,-2.43,;-.19,-2.9,;-1.52,-2.13,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198267 (US9216999, 74 | US9556187, Example 74) Show SMILES BrC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:5.8,wD:2.1,(4,4.07,;2.51,4.47,;1.42,3.38,;-.06,3.78,;-1.15,2.69,;-.75,1.2,;.73,.81,;1.82,1.89,;-1.84,.12,;-3.37,.28,;-4,-1.13,;-2.86,-2.16,;-2.86,-3.7,;-1.52,-4.47,;-.19,-3.7,;1.28,-4.18,;2.18,-2.93,;1.28,-1.69,;-.19,-2.16,;-1.52,-1.39,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM411423 (US10385052, Example 4) Show SMILES Cc1cnn(CC2CCC(CC2)N2C=CC(=O)C3C=Nc4[nH]ccc4C23)c1 |c:14,19,(9.12,3.4,;7.62,3.72,;6.71,2.47,;5.25,2.95,;5.25,4.49,;4,5.39,;2.67,4.62,;2.67,3.08,;1.33,2.31,;0,3.08,;0,4.62,;1.33,5.39,;-1.33,2.31,;-2.67,3.08,;-4,2.31,;-4,.77,;-5.33,0,;-2.67,0,;-2.67,-1.54,;-1.33,-2.31,;0,-1.54,;1.46,-2.02,;2.37,-.77,;1.47,.48,;0,0,;-1.33,.77,;6.71,4.96,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
Nissan Chemical Corporation US Patent					Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...				US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198228 (US9216999, 36 | US9556187, Example 36) Show SMILES Cc1noc(C)c1CN1CCC(CC1)c1nnn2cnc3[nH]ccc3c12 Show InChI InChI=1S/C18H21N7O/c1-11-15(12(2)26-22-11)9-24-7-4-13(5-8-24)16-17-14-3-6-19-18(14)20-10-25(17)23-21-16/h3,6,10,13,19H,4-5,7-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.580	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM411424 (US10385052, Example 5) Show SMILES FC(F)(F)COCC1CCC(CC1)N1C=CC(=O)C2C=Nc3[nH]ccc3C12 |c:15,20,(5.89,7.5,;7.03,6.47,;8.5,6.94,;8.18,5.44,;6.71,4.96,;5.25,4.49,;4,5.39,;2.67,4.62,;2.67,3.08,;1.33,2.31,;0,3.08,;0,4.62,;1.33,5.39,;-1.33,2.31,;-2.67,3.08,;-4,2.31,;-4,.77,;-5.33,0,;-2.67,0,;-2.67,-1.54,;-1.33,-2.31,;0,-1.54,;1.46,-2.02,;2.37,-.77,;1.47,.48,;0,0,;-1.33,.77,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
Nissan Chemical Corporation US Patent					Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...				US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198241 (US9216999, 49 | US9556187, Example 49) Show SMILES Clc1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)s1 Show InChI InChI=1S/C17H17ClN6S/c18-14-2-1-12(25-14)9-23-7-4-11(5-8-23)15-16-13-3-6-19-17(13)20-10-24(16)22-21-15/h1-3,6,10-11,19H,4-5,7-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.610	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198241 (US9216999, 49 | US9556187, Example 49) Show SMILES Clc1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)s1 Show InChI InChI=1S/C17H17ClN6S/c18-14-2-1-12(25-14)9-23-7-4-11(5-8-23)15-16-13-3-6-19-17(13)20-10-24(16)22-21-15/h1-3,6,10-11,19H,4-5,7-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198343 (US9216999, 144 | US9556187, Example 144) Show SMILES N#Cc1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)s1 Show InChI InChI=1S/C18H17N7S/c19-9-13-1-2-14(26-13)10-24-7-4-12(5-8-24)16-17-15-3-6-20-18(15)21-11-25(17)23-22-16/h1-3,6,11-12,20H,4-5,7-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.660	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198343 (US9216999, 144 | US9556187, Example 144) Show SMILES N#Cc1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)s1 Show InChI InChI=1S/C18H17N7S/c19-9-13-1-2-14(26-13)10-24-7-4-12(5-8-24)16-17-15-3-6-20-18(15)21-11-25(17)23-22-16/h1-3,6,11-12,20H,4-5,7-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.660	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM411425 (US10385052, Example 6) Show SMILES FC(F)(F)CCOCC1CCC(CC1)N1C=CC(=O)C2C=Nc3[nH]ccc3C12 |c:16,21,(8.82,8.45,;8.5,6.94,;9.64,5.91,;8.18,5.44,;7.03,6.47,;6.71,4.96,;5.25,4.49,;4,5.39,;2.67,4.62,;2.67,3.08,;1.33,2.31,;0,3.08,;0,4.62,;1.33,5.39,;-1.33,2.31,;-2.67,3.08,;-4,2.31,;-4,.77,;-5.33,0,;-2.67,0,;-2.67,-1.54,;-1.33,-2.31,;0,-1.54,;1.46,-2.02,;2.37,-.77,;1.47,.48,;0,0,;-1.33,.77,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.680	n/a	n/a	n/a	n/a	n/a	n/a
Nissan Chemical Corporation US Patent					Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...				US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198357 (US9216999, 158 | US9556187, Example 158) Show SMILES Fc1cc(Cl)ccc1CN1CCC(CC1)c1nnn2cnc3[nH]ccc3c12 Show InChI InChI=1S/C19H18ClFN6/c20-14-2-1-13(16(21)9-14)10-26-7-4-12(5-8-26)17-18-15-3-6-22-19(15)23-11-27(18)25-24-17/h1-3,6,9,11-12,22H,4-5,7-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198357 (US9216999, 158 | US9556187, Example 158) Show SMILES Fc1cc(Cl)ccc1CN1CCC(CC1)c1nnn2cnc3[nH]ccc3c12 Show InChI InChI=1S/C19H18ClFN6/c20-14-2-1-13(16(21)9-14)10-26-7-4-12(5-8-26)17-18-15-3-6-22-19(15)23-11-27(18)25-24-17/h1-3,6,9,11-12,22H,4-5,7-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM411426 (US10385052, Example 7) Show SMILES FC(F)(F)[C@H](CC#N)OCC1CCC(CC1)N1C=CC(=O)C2C=Nc3[nH]ccc3C12 |r,wU:4.7,c:18,23,(7.54,2.43,;7.86,3.93,;9.32,4.41,;9,2.9,;6.71,4.96,;7.03,6.47,;8.5,6.94,;8.82,8.45,;5.25,4.49,;4,5.39,;2.67,4.62,;2.67,3.08,;1.33,2.31,;0,3.08,;0,4.62,;1.33,5.39,;-1.33,2.31,;-2.67,3.08,;-4,2.31,;-4,.77,;-5.33,0,;-2.67,0,;-2.67,-1.54,;-1.33,-2.31,;0,-1.54,;1.46,-2.02,;2.37,-.77,;1.47,.48,;0,0,;-1.33,.77,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.740	n/a	n/a	n/a	n/a	n/a	n/a
Nissan Chemical Corporation US Patent					Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...				US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198218 (US9216999, 26 | US9556187, Example 84) Show SMILES O=C(OCc1ccccc1)N1CCC(CC1)c1nnn2cnc3[nH]ccc3c12 Show InChI InChI=1S/C20H20N6O2/c27-20(28-12-14-4-2-1-3-5-14)25-10-7-15(8-11-25)17-18-16-6-9-21-19(16)22-13-26(18)24-23-17/h1-6,9,13,15,21H,7-8,10-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198441 (US9216999, 238 | US9556187, Example 238) Show SMILES Brc1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)s1 Show InChI InChI=1S/C17H17BrN6S/c18-14-2-1-12(25-14)9-23-7-4-11(5-8-23)15-16-13-3-6-19-17(13)20-10-24(16)22-21-15/h1-3,6,10-11,19H,4-5,7-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.790	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198441 (US9216999, 238 | US9556187, Example 238) Show SMILES Brc1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)s1 Show InChI InChI=1S/C17H17BrN6S/c18-14-2-1-12(25-14)9-23-7-4-11(5-8-23)15-16-13-3-6-19-17(13)20-10-24(16)22-21-15/h1-3,6,10-11,19H,4-5,7-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.790	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198264 (US9216999, 71 | US9556187, Example 71) Show SMILES CC(=O)SC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:8.11,wD:5.4,(5.29,3.67,;3.8,4.07,;3.4,5.56,;2.71,2.98,;1.22,3.38,;.14,2.29,;-1.35,2.69,;-2.44,1.6,;-2.04,.12,;-.55,-.28,;.53,.81,;-3.13,-.97,;-4.66,-.81,;-5.29,-2.22,;-4.14,-3.25,;-4.14,-4.79,;-2.81,-5.56,;-1.48,-4.79,;-.01,-5.27,;.89,-4.02,;-.01,-2.77,;-1.48,-3.25,;-2.81,-2.48,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	0.940	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198264 (US9216999, 71 | US9556187, Example 71) Show SMILES CC(=O)SC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:8.11,wD:5.4,(5.29,3.67,;3.8,4.07,;3.4,5.56,;2.71,2.98,;1.22,3.38,;.14,2.29,;-1.35,2.69,;-2.44,1.6,;-2.04,.12,;-.55,-.28,;.53,.81,;-3.13,-.97,;-4.66,-.81,;-5.29,-2.22,;-4.14,-3.25,;-4.14,-4.79,;-2.81,-5.56,;-1.48,-4.79,;-.01,-5.27,;.89,-4.02,;-.01,-2.77,;-1.48,-3.25,;-2.81,-2.48,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	0.940	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198349 (US9216999, 150 | US9556187, Example 150) Show SMILES Clc1ncc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)s1 Show InChI InChI=1S/C16H16ClN7S/c17-16-19-7-11(25-16)8-23-5-2-10(3-6-23)13-14-12-1-4-18-15(12)20-9-24(14)22-21-13/h1,4,7,9-10,18H,2-3,5-6,8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.980	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198349 (US9216999, 150 | US9556187, Example 150) Show SMILES Clc1ncc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)s1 Show InChI InChI=1S/C16H16ClN7S/c17-16-19-7-11(25-16)8-23-5-2-10(3-6-23)13-14-12-1-4-18-15(12)20-9-24(14)22-21-13/h1,4,7,9-10,18H,2-3,5-6,8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.980	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM411420 (US10385052, Example 1) Show SMILES FC(F)(F)[C@@H](CC#N)NCC1CCC(CC1)[C@H]1C2C(C=Nc3[nH]ccc23)C(=O)NC1=O |r,wU:16.16,4.7,c:20,(5.25,7.57,;6.58,6.8,;7.92,7.57,;7.92,6.03,;6.58,5.26,;7.92,4.49,;7.92,2.95,;6.58,2.18,;5.25,4.49,;4,5.39,;2.67,4.62,;2.67,3.08,;1.33,2.31,;0,3.08,;0,4.62,;1.33,5.39,;-1.33,2.31,;-1.33,.77,;-2.67,0,;-2.67,-1.54,;-1.33,-2.31,;0,-1.54,;1.46,-2.02,;2.37,-.77,;1.47,.48,;0,0,;-4,.77,;-5.33,0,;-4,2.31,;-2.67,3.08,;-2.67,4.62,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.990	n/a	n/a	n/a	n/a	n/a	n/a
Nissan Chemical Corporation US Patent					Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...				US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198570 (US9216999, 367 | US9556187, Example 367) Show SMILES IC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:5.8,wD:2.1,(4,4.07,;2.51,4.47,;1.42,3.38,;-.06,3.78,;-1.15,2.69,;-.75,1.2,;.73,.81,;1.82,1.89,;-1.84,.12,;-3.37,.28,;-4,-1.13,;-2.86,-2.16,;-2.86,-3.7,;-1.52,-4.47,;-.19,-3.7,;1.28,-4.18,;2.18,-2.93,;1.28,-1.69,;-.19,-2.16,;-1.52,-1.39,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.990	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198570 (US9216999, 367 | US9556187, Example 367) Show SMILES IC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:5.8,wD:2.1,(4,4.07,;2.51,4.47,;1.42,3.38,;-.06,3.78,;-1.15,2.69,;-.75,1.2,;.73,.81,;1.82,1.89,;-1.84,.12,;-3.37,.28,;-4,-1.13,;-2.86,-2.16,;-2.86,-3.7,;-1.52,-4.47,;-.19,-3.7,;1.28,-4.18,;2.18,-2.93,;1.28,-1.69,;-.19,-2.16,;-1.52,-1.39,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.990	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198470 (US9216999, 267 | US9556187, Example 267) Show SMILES O[C@@H]1CCN(C[C@H]2CC[C@@H](CC2)c2nnn3cnc4[nH]ccc4c23)C1 |r,wU:9.12,wD:6.5,1.0,(5.85,5.04,;4.52,4.27,;4.52,2.73,;3.05,2.26,;2.15,3.5,;.66,3.9,;-.43,2.81,;-1.92,3.21,;-3,2.12,;-2.61,.63,;-1.12,.24,;-.03,1.32,;-3.69,-.46,;-5.23,-.29,;-5.85,-1.7,;-4.71,-2.73,;-4.71,-4.27,;-3.37,-5.04,;-2.04,-4.27,;-.58,-4.75,;.33,-3.5,;-.58,-2.26,;-2.04,-2.73,;-3.37,-1.96,;3.05,4.75,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198352 (US9216999, 153 | US9556187, Example 153) Show SMILES Brc1ncc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)s1 Show InChI InChI=1S/C16H16BrN7S/c17-16-19-7-11(25-16)8-23-5-2-10(3-6-23)13-14-12-1-4-18-15(12)20-9-24(14)22-21-13/h1,4,7,9-10,18H,2-3,5-6,8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198352 (US9216999, 153 | US9556187, Example 153) Show SMILES Brc1ncc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)s1 Show InChI InChI=1S/C16H16BrN7S/c17-16-19-7-11(25-16)8-23-5-2-10(3-6-23)13-14-12-1-4-18-15(12)20-9-24(14)22-21-13/h1,4,7,9-10,18H,2-3,5-6,8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM198268 (US9216999, 75 | US9556187, Example 75) Show SMILES ClC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:5.8,wD:2.1,(4,4.07,;2.51,4.47,;1.42,3.38,;-.06,3.78,;-1.15,2.69,;-.75,1.2,;.73,.81,;1.82,1.89,;-1.84,.12,;-3.37,.28,;-4,-1.13,;-2.86,-2.16,;-2.86,-3.7,;-1.52,-4.47,;-.19,-3.7,;1.28,-4.18,;2.18,-2.93,;1.28,-1.69,;-.19,-2.16,;-1.52,-1.39,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198470 (US9216999, 267 | US9556187, Example 267) Show SMILES O[C@@H]1CCN(C[C@H]2CC[C@@H](CC2)c2nnn3cnc4[nH]ccc4c23)C1 |r,wU:9.12,wD:6.5,1.0,(5.85,5.04,;4.52,4.27,;4.52,2.73,;3.05,2.26,;2.15,3.5,;.66,3.9,;-.43,2.81,;-1.92,3.21,;-3,2.12,;-2.61,.63,;-1.12,.24,;-.03,1.32,;-3.69,-.46,;-5.23,-.29,;-5.85,-1.7,;-4.71,-2.73,;-4.71,-4.27,;-3.37,-5.04,;-2.04,-4.27,;-.58,-4.75,;.33,-3.5,;-.58,-2.26,;-2.04,-2.73,;-3.37,-1.96,;3.05,4.75,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	25
NISSAN CHEMICAL INDUSTRIES, LTD. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9556187 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R1V
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM198268 (US9216999, 75 | US9556187, Example 75) Show SMILES ClC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:5.8,wD:2.1,(4,4.07,;2.51,4.47,;1.42,3.38,;-.06,3.78,;-1.15,2.69,;-.75,1.2,;.73,.81,;1.82,1.89,;-1.84,.12,;-3.37,.28,;-4,-1.13,;-2.86,-2.16,;-2.86,-3.7,;-1.52,-4.47,;-.19,-3.7,;1.28,-4.18,;2.18,-2.93,;1.28,-1.69,;-.19,-2.16,;-1.52,-1.39,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198456 (US9216999, 253 | US9556187, Example 253) Show SMILES O=C1SCCC1NC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12 |r,wU:11.15,wD:8.8,(5.7,2.3,;4.93,3.63,;5.41,5.1,;4.16,6,;2.91,5.1,;3.39,3.63,;2.3,2.54,;.81,2.94,;-.28,1.85,;-1.76,2.25,;-2.85,1.16,;-2.45,-.33,;-.97,-.72,;.12,.36,;-3.54,-1.41,;-5.07,-1.25,;-5.7,-2.66,;-4.56,-3.69,;-4.56,-5.23,;-3.22,-6,;-1.89,-5.23,;-.42,-5.71,;.48,-4.46,;-.42,-3.22,;-1.89,-3.69,;-3.22,-2.92,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM198233 (US9216999, 41 | US9556187, Example 41) Show SMILES Brc1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)cc1 Show InChI InChI=1S/C19H19BrN6/c20-15-3-1-13(2-4-15)11-25-9-6-14(7-10-25)17-18-16-5-8-21-19(16)22-12-26(18)24-23-17/h1-5,8,12,14,21H,6-7,9-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.5	n/a
Nissan Chemical Industries, Ltd. US Patent					Assay Description JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...				US Patent US9216999 (2015) BindingDB Entry DOI: 10.7270/Q28C9V2J
					More data for this Ligand-Target Pair

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