Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysophosphatidic acid receptor 1 (Homo sapiens (Human)) | BDBM50285779 (CHEMBL4165205) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Antagonist activity at recombinant human LPA1 expressed in CHO cell membranes pretreated for 24 hrs prior to Fura-2-AM dye addition for 1 hr followed... | ACS Med Chem Lett 8: 1281-1286 (2017) Article DOI: 10.1021/acsmedchemlett.7b00383 BindingDB Entry DOI: 10.7270/Q2PG1V8Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 1 (Homo sapiens (Human)) | BDBM50285779 (CHEMBL4165205) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Antagonist activity at recombinant human LPA1 expressed in CHO cell membranes pretreated for 24 hrs prior to Fura-2-AM dye addition for 1 hr followed... | ACS Med Chem Lett 8: 1281-1286 (2017) Article DOI: 10.1021/acsmedchemlett.7b00383 BindingDB Entry DOI: 10.7270/Q2PG1V8Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 1 (Homo sapiens (Human)) | BDBM50285779 (CHEMBL4165205) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Antagonist activity at recombinant human LPA1 expressed in CHO cells assessed as reduction in LPA-induced intracellular calcium level pretreated foll... | ACS Med Chem Lett 8: 1281-1286 (2017) Article DOI: 10.1021/acsmedchemlett.7b00383 BindingDB Entry DOI: 10.7270/Q2PG1V8Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 1 (Homo sapiens (Human)) | BDBM50285779 (CHEMBL4165205) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a |
ONO Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Binding affinity to recombinant human LPA1 expressed in CHO cell membranes measured after 2 hrs at 4 degC by scintillation counting method | ACS Med Chem Lett 8: 1281-1286 (2017) Article DOI: 10.1021/acsmedchemlett.7b00383 BindingDB Entry DOI: 10.7270/Q2PG1V8Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 1 (Homo sapiens (Human)) | BDBM50285779 (CHEMBL4165205) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.490 | n/a | n/a | n/a | n/a | n/a |
ONO Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Binding affinity to recombinant human LPA1 expressed in CHO cell membranes measured after 4 hrs by scintillation counting method | ACS Med Chem Lett 8: 1281-1286 (2017) Article DOI: 10.1021/acsmedchemlett.7b00383 BindingDB Entry DOI: 10.7270/Q2PG1V8Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 1 (Homo sapiens (Human)) | BDBM50285779 (CHEMBL4165205) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.340 | n/a | n/a | n/a | n/a | n/a |
ONO Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Binding affinity to recombinant human LPA1 expressed in CHO cell membranes measured after 2 hrs at 37 degC by scintillation counting method | ACS Med Chem Lett 8: 1281-1286 (2017) Article DOI: 10.1021/acsmedchemlett.7b00383 BindingDB Entry DOI: 10.7270/Q2PG1V8Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 1 (Homo sapiens (Human)) | BDBM50285779 (CHEMBL4165205) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.740 | n/a | n/a | n/a | n/a | n/a |
ONO Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Binding affinity to recombinant human LPA1 expressed in CHO cell membranes measured after 2 hrs at room temperature by scintillation counting method | ACS Med Chem Lett 8: 1281-1286 (2017) Article DOI: 10.1021/acsmedchemlett.7b00383 BindingDB Entry DOI: 10.7270/Q2PG1V8Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 1 (Homo sapiens (Human)) | BDBM50285779 (CHEMBL4165205) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.740 | n/a | n/a | n/a | n/a | n/a |
ONO Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Binding affinity to recombinant human LPA1 expressed in CHO cell membranes measured after 2 hrs by scintillation counting method | ACS Med Chem Lett 8: 1281-1286 (2017) Article DOI: 10.1021/acsmedchemlett.7b00383 BindingDB Entry DOI: 10.7270/Q2PG1V8Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 1 (Homo sapiens (Human)) | BDBM50285779 (CHEMBL4165205) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a |
ONO Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Binding affinity to recombinant human LPA1 expressed in CHO cell membranes measured after 0.5 hrs by scintillation counting method | ACS Med Chem Lett 8: 1281-1286 (2017) Article DOI: 10.1021/acsmedchemlett.7b00383 BindingDB Entry DOI: 10.7270/Q2PG1V8Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 1 (Homo sapiens (Human)) | BDBM50285779 (CHEMBL4165205) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a |
ONO Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Binding affinity to recombinant human LPA1 expressed in CHO cell membranes measured after 1 hr by scintillation counting method | ACS Med Chem Lett 8: 1281-1286 (2017) Article DOI: 10.1021/acsmedchemlett.7b00383 BindingDB Entry DOI: 10.7270/Q2PG1V8Z | |||||||||||
More data for this Ligand-Target Pair |