Found 119 hits with Last Name = 'misura' and Initial = 'as' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211814
(4-(2-(4-fluorophenyl)-7-((isopropylamino)methyl)H-...)Show SMILES CC(C)NCc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N[C@@H](C)c2ccccc2)n1 Show InChI InChI=1S/C29H29FN6/c1-19(2)32-18-21-14-16-36-26(17-21)35-27(23-9-11-24(30)12-10-23)28(36)25-13-15-31-29(34-25)33-20(3)22-7-5-4-6-8-22/h4-17,19-20,32H,18H2,1-3H3,(H,31,33,34)/t20-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211811
(4-(7-((dimethylamino)methyl)-2-(4-fluorophenyl)H-i...)Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(Nc2ccccc2)n1 Show InChI InChI=1S/C26H23FN6/c1-32(2)17-18-13-15-33-23(16-18)31-24(19-8-10-20(27)11-9-19)25(33)22-12-14-28-26(30-22)29-21-6-4-3-5-7-21/h3-16H,17H2,1-2H3,(H,28,29,30) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374578
(CHEMBL401749)Show SMILES Fc1ccc(cc1)-c1[nH]c(cc1-c1ccncc1)C1CCN(CC2CNCCN2)CC1 |w:23.25| Show InChI InChI=1S/C25H30FN5/c26-21-3-1-20(2-4-21)25-23(18-5-9-27-10-6-18)15-24(30-25)19-7-13-31(14-8-19)17-22-16-28-11-12-29-22/h1-6,9-10,15,19,22,28-30H,7-8,11-14,16-17H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211805
(4-(7-(((3-(dimethylamino)propyl)(methyl)amino)meth...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CCCN(C)C)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C32H36FN7/c1-23(25-9-6-5-7-10-25)35-32-34-17-15-28(36-32)31-30(26-11-13-27(33)14-12-26)37-29-21-24(16-20-40(29)31)22-39(4)19-8-18-38(2)3/h5-7,9-17,20-21,23H,8,18-19,22H2,1-4H3,(H,34,35,36)/t23-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374594
(CHEMBL444009)Show SMILES Fc1ccc(cc1)-c1[nH]c(cc1-c1ccncc1)C1CCN(CCN2CCC2)CC1 Show InChI InChI=1S/C25H29FN4/c26-22-4-2-21(3-5-22)25-23(19-6-10-27-11-7-19)18-24(28-25)20-8-14-30(15-9-20)17-16-29-12-1-13-29/h2-7,10-11,18,20,28H,1,8-9,12-17H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50182359
(CHEMBL379059 | N-benzyl-4-(7-((dimethylamino)methy...)Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCc2ccccc2)n1 Show InChI InChI=1S/C27H25FN6/c1-33(2)18-20-13-15-34-24(16-20)32-25(21-8-10-22(28)11-9-21)26(34)23-12-14-29-27(31-23)30-17-19-6-4-3-5-7-19/h3-16H,17-18H2,1-2H3,(H,29,30,31) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.0810 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211820
(4-(7-(((2-(azetidin-1-yl)ethyl)(methyl)amino)methy...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CCN3CCC3)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C32H34FN7/c1-23(25-7-4-3-5-8-25)35-32-34-15-13-28(36-32)31-30(26-9-11-27(33)12-10-26)37-29-21-24(14-18-40(29)31)22-38(2)19-20-39-16-6-17-39/h3-5,7-15,18,21,23H,6,16-17,19-20,22H2,1-2H3,(H,34,35,36)/t23-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211812
(4-(2-(4-fluorophenyl)-7-((isopropyl(methyl)amino)m...)Show SMILES CC(C)N(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N[C@@H](C)c2ccccc2)n1 Show InChI InChI=1S/C30H31FN6/c1-20(2)36(4)19-22-15-17-37-27(18-22)35-28(24-10-12-25(31)13-11-24)29(37)26-14-16-32-30(34-26)33-21(3)23-8-6-5-7-9-23/h5-18,20-21H,19H2,1-4H3,(H,32,33,34)/t21-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211802
(2-(((2-(4-fluorophenyl)-3-(2-((S)-1-phenylethylami...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CCO)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C29H29FN6O/c1-20(22-6-4-3-5-7-22)32-29-31-14-12-25(33-29)28-27(23-8-10-24(30)11-9-23)34-26-18-21(13-15-36(26)28)19-35(2)16-17-37/h3-15,18,20,37H,16-17,19H2,1-2H3,(H,31,32,33)/t20-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211803
(4-(7-((ethyl(methyl)amino)methyl)-2-(4-fluoropheny...)Show SMILES CCN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N[C@@H](C)c2ccccc2)n1 Show InChI InChI=1S/C29H29FN6/c1-4-35(3)19-21-15-17-36-26(18-21)34-27(23-10-12-24(30)13-11-23)28(36)25-14-16-31-29(33-25)32-20(2)22-8-6-5-7-9-22/h5-18,20H,4,19H2,1-3H3,(H,31,32,33)/t20-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211808
(CHEMBL233008 | N-(2-(((2-(4-fluorophenyl)-3-(2-((S...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CCNS(C)(=O)=O)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C30H32FN7O2S/c1-21(23-7-5-4-6-8-23)34-30-32-15-13-26(35-30)29-28(24-9-11-25(31)12-10-24)36-27-19-22(14-17-38(27)29)20-37(2)18-16-33-41(3,39)40/h4-15,17,19,21,33H,16,18,20H2,1-3H3,(H,32,34,35)/t21-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211821
(2-(((2-(4-fluorophenyl)-3-(2-((S)-1-phenylethylami...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)C(CO)CO)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C30H31FN6O2/c1-20(22-6-4-3-5-7-22)33-30-32-14-12-26(34-30)29-28(23-8-10-24(31)11-9-23)35-27-16-21(13-15-37(27)29)17-36(2)25(18-38)19-39/h3-16,20,25,38-39H,17-19H2,1-2H3,(H,32,33,34)/t20-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171694
((R)-5-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-py...)Show SMILES O[C@H]1CNC(CN2CCC(CC2)c2cc(c([nH]2)-c2ccc(F)cc2)-c2ccncc2)C1 Show InChI InChI=1S/C25H29FN4O/c26-20-3-1-19(2-4-20)25-23(17-5-9-27-10-6-17)14-24(29-25)18-7-11-30(12-8-18)16-21-13-22(31)15-28-21/h1-6,9-10,14,18,21-22,28-29,31H,7-8,11-13,15-16H2/t21?,22-/m1/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374591
(CHEMBL255128)Show SMILES O[C@H]1CN[C@H](CN2CCC(CC2)c2cc(c([nH]2)-c2ccc(F)cc2)-c2ccncc2)C1 Show InChI InChI=1S/C25H29FN4O/c26-20-3-1-19(2-4-20)25-23(17-5-9-27-10-6-17)14-24(29-25)18-7-11-30(12-8-18)16-21-13-22(31)15-28-21/h1-6,9-10,14,18,21-22,28-29,31H,7-8,11-13,15-16H2/t21-,22+/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374587
(CHEMBL272573)Show SMILES Fc1ccc(cc1)-c1[nH]c(cc1-c1ccncc1)C1CCN(CC2CNCCO2)CC1 |w:23.25| Show InChI InChI=1S/C25H29FN4O/c26-21-3-1-20(2-4-21)25-23(18-5-9-27-10-6-18)15-24(29-25)19-7-12-30(13-8-19)17-22-16-28-11-14-31-22/h1-6,9-10,15,19,22,28-29H,7-8,11-14,16-17H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211819
(4-(7-((dimethylamino)methyl)-2-(4-fluorophenyl)H-i...)Show SMILES CC(C)Nc1nccc(n1)-c1c(nc2cc(CN(C)C)ccn12)-c1ccc(F)cc1 Show InChI InChI=1S/C23H25FN6/c1-15(2)26-23-25-11-9-19(27-23)22-21(17-5-7-18(24)8-6-17)28-20-13-16(14-29(3)4)10-12-30(20)22/h5-13,15H,14H2,1-4H3,(H,25,26,27) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211816
((S)-2-(((2-(4-fluorophenyl)-3-(2-((S)-1-phenylethy...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)[C@@H](C)C(=O)N(C)C)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C32H34FN7O/c1-21(24-9-7-6-8-10-24)35-32-34-17-15-27(36-32)30-29(25-11-13-26(33)14-12-25)37-28-19-23(16-18-40(28)30)20-39(5)22(2)31(41)38(3)4/h6-19,21-22H,20H2,1-5H3,(H,34,35,36)/t21-,22-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374588
(CHEMBL255381)Show SMILES Fc1ccc(cc1)-c1[nH]c(cc1-c1ccncc1)C1CCN(CC1)C(=O)C1CNCCO1 |w:26.29| Show InChI InChI=1S/C25H27FN4O2/c26-20-3-1-19(2-4-20)24-21(17-5-9-27-10-6-17)15-22(29-24)18-7-12-30(13-8-18)25(31)23-16-28-11-14-32-23/h1-6,9-10,15,18,23,28-29H,7-8,11-14,16H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211810
(4-(2-(4-fluorophenyl)-7-((methyl((tetrahydrofuran-...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CC3CCCO3)ccn12)-c1ccc(F)cc1)c1ccccc1 |w:19.19| Show InChI InChI=1S/C32H33FN6O/c1-22(24-7-4-3-5-8-24)35-32-34-16-14-28(36-32)31-30(25-10-12-26(33)13-11-25)37-29-19-23(15-17-39(29)31)20-38(2)21-27-9-6-18-40-27/h3-5,7-8,10-17,19,22,27H,6,9,18,20-21H2,1-2H3,(H,34,35,36)/t22-,27?/m0/s1 | UniProtKB/TrEMBL
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50182361
(4-(7-((dimethylamino)methyl)-2-(4-fluorophenyl)H-i...)Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCC(C)(C)C)n1 Show InChI InChI=1S/C25H29FN6/c1-25(2,3)16-28-24-27-12-10-20(29-24)23-22(18-6-8-19(26)9-7-18)30-21-14-17(15-31(4)5)11-13-32(21)23/h6-14H,15-16H2,1-5H3,(H,27,28,29) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374592
(CHEMBL271922)Show SMILES CN1CC[C@H]1CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C25H29FN4/c1-29-13-10-22(29)17-30-14-8-19(9-15-30)24-16-23(18-6-11-27-12-7-18)25(28-24)20-2-4-21(26)5-3-20/h2-7,11-12,16,19,22,28H,8-10,13-15,17H2,1H3/t22-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211823
(4-(7-((ethyl(methyl)amino)methyl)-2-(4-fluoropheny...)Show SMILES CCN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCC(C)(C)C)n1 Show InChI InChI=1S/C26H31FN6/c1-6-32(5)16-18-12-14-33-22(15-18)31-23(19-7-9-20(27)10-8-19)24(33)21-11-13-28-25(30-21)29-17-26(2,3)4/h7-15H,6,16-17H2,1-5H3,(H,28,29,30) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211818
(CHEMBL233011 | N-tert-butyl-4-(7-((dimethylamino)m...)Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NC(C)(C)C)n1 Show InChI InChI=1S/C24H27FN6/c1-24(2,3)29-23-26-12-10-19(27-23)22-21(17-6-8-18(25)9-7-17)28-20-14-16(15-30(4)5)11-13-31(20)22/h6-14H,15H2,1-5H3,(H,26,27,29) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374580
(CHEMBL271638)Show SMILES CN1C[C@H](O)C[C@H]1CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C26H31FN4O/c1-30-17-23(32)14-22(30)16-31-12-8-19(9-13-31)25-15-24(18-6-10-28-11-7-18)26(29-25)20-2-4-21(27)5-3-20/h2-7,10-11,15,19,22-23,29,32H,8-9,12-14,16-17H2,1H3/t22-,23+/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.340 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50183915
((5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-pyrrol-2-y...)Show InChI InChI=1S/C18H18FN3/c1-22(2)12-16-11-17(13-7-9-20-10-8-13)18(21-16)14-3-5-15(19)6-4-14/h3-11,21H,12H2,1-2H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.350 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella PKG |
Bioorg Med Chem Lett 16: 2817-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.01.041
BindingDB Entry DOI: 10.7270/Q21V5DK1 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374590
(CHEMBL406910)Show SMILES CCN1C[C@H](O)C[C@H]1CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C27H33FN4O/c1-2-32-18-24(33)15-23(32)17-31-13-9-20(10-14-31)26-16-25(19-7-11-29-12-8-19)27(30-26)21-3-5-22(28)6-4-21/h3-8,11-12,16,20,23-24,30,33H,2,9-10,13-15,17-18H2,1H3/t23-,24+/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.360 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171685
(1-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol...)Show SMILES CCCC(O)CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C25H30FN3O/c1-2-3-22(30)17-29-14-10-19(11-15-29)24-16-23(18-8-12-27-13-9-18)25(28-24)20-4-6-21(26)7-5-20/h4-9,12-13,16,19,22,28,30H,2-3,10-11,14-15,17H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211822
(2-(((2-(4-fluorophenyl)-3-(2-((S)-1-phenylethylami...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CC(=O)N3CCCC3)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C33H34FN7O/c1-23(25-8-4-3-5-9-25)36-33-35-16-14-28(37-33)32-31(26-10-12-27(34)13-11-26)38-29-20-24(15-19-41(29)32)21-39(2)22-30(42)40-17-6-7-18-40/h3-5,8-16,19-20,23H,6-7,17-18,21-22H2,1-2H3,(H,35,36,37)/t23-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374593
(CHEMBL429745)Show SMILES CC(CN1CCC1)N1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 |w:1.0| Show InChI InChI=1S/C26H31FN4/c1-19(18-30-13-2-14-30)31-15-9-21(10-16-31)25-17-24(20-7-11-28-12-8-20)26(29-25)22-3-5-23(27)6-4-22/h3-8,11-12,17,19,21,29H,2,9-10,13-16,18H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171698
(1-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol...)Show SMILES CC(O)C(O)CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C24H28FN3O2/c1-16(29)23(30)15-28-12-8-18(9-13-28)22-14-21(17-6-10-26-11-7-17)24(27-22)19-2-4-20(25)5-3-19/h2-7,10-11,14,16,18,23,27,29-30H,8-9,12-13,15H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171707
(1-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol...)Show SMILES CCCCC(O)CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C26H32FN3O/c1-2-3-4-23(31)18-30-15-11-20(12-16-30)25-17-24(19-9-13-28-14-10-19)26(29-25)21-5-7-22(27)8-6-21/h5-10,13-14,17,20,23,29,31H,2-4,11-12,15-16,18H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.410 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211817
(4-(7-(azetidin-1-ylmethyl)-2-(4-fluorophenyl)H-imi...)Show SMILES CC(C)(C)CNc1nccc(n1)-c1c(nc2cc(CN3CCC3)ccn12)-c1ccc(F)cc1 Show InChI InChI=1S/C26H29FN6/c1-26(2,3)17-29-25-28-11-9-21(30-25)24-23(19-5-7-20(27)8-6-19)31-22-15-18(10-14-33(22)24)16-32-12-4-13-32/h5-11,14-15H,4,12-13,16-17H2,1-3H3,(H,28,29,30) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171705
(1-Benzyloxy-3-{4-[5-(4-fluoro-phenyl)-4-pyridin-4-...)Show SMILES OC(COCc1ccccc1)CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C30H32FN3O2/c31-26-8-6-25(7-9-26)30-28(23-10-14-32-15-11-23)18-29(33-30)24-12-16-34(17-13-24)19-27(35)21-36-20-22-4-2-1-3-5-22/h1-11,14-15,18,24,27,33,35H,12-13,16-17,19-21H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171699
((S)-1-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-py...)Show SMILES C[C@H](O)CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C23H26FN3O/c1-16(28)15-27-12-8-18(9-13-27)22-14-21(17-6-10-25-11-7-17)23(26-22)19-2-4-20(24)5-3-19/h2-7,10-11,14,16,18,26,28H,8-9,12-13,15H2,1H3/t16-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.480 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171693
(3-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol...)Show SMILES OCC(O)CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C23H26FN3O2/c24-19-3-1-18(2-4-19)23-21(16-5-9-25-10-6-16)13-22(26-23)17-7-11-27(12-8-17)14-20(29)15-28/h1-6,9-10,13,17,20,26,28-29H,7-8,11-12,14-15H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.510 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171693
(3-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol...)Show SMILES OCC(O)CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C23H26FN3O2/c24-19-3-1-18(2-4-19)23-21(16-5-9-25-10-6-16)13-22(26-23)17-7-11-27(12-8-17)14-20(29)15-28/h1-6,9-10,13,17,20,26,28-29H,7-8,11-12,14-15H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.510 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50168176
(3-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol...)Show SMILES OCCCN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C23H26FN3O/c24-20-4-2-19(3-5-20)23-21(17-6-10-25-11-7-17)16-22(26-23)18-8-13-27(14-9-18)12-1-15-28/h2-7,10-11,16,18,26,28H,1,8-9,12-15H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.530 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171695
((R)1-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyr...)Show SMILES COCC(O)CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C24H28FN3O2/c1-30-16-21(29)15-28-12-8-18(9-13-28)23-14-22(17-6-10-26-11-7-17)24(27-23)19-2-4-20(25)5-3-19/h2-7,10-11,14,18,21,27,29H,8-9,12-13,15-16H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.560 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211815
(1-(azetidin-1-yl)-2-(((2-(4-fluorophenyl)-3-(2-((S...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CC(=O)N3CCC3)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C32H32FN7O/c1-22(24-7-4-3-5-8-24)35-32-34-15-13-27(36-32)31-30(25-9-11-26(33)12-10-25)37-28-19-23(14-18-40(28)31)20-38(2)21-29(41)39-16-6-17-39/h3-5,7-15,18-19,22H,6,16-17,20-21H2,1-2H3,(H,34,35,36)/t22-/m0/s1 | UniProtKB/TrEMBL
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171688
(1-Ethoxy-3-{4-[5-(4-fluoro-phenyl)-4-pyridin-4-yl-...)Show SMILES CCOCC(O)CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C25H30FN3O2/c1-2-31-17-22(30)16-29-13-9-19(10-14-29)24-15-23(18-7-11-27-12-8-18)25(28-24)20-3-5-21(26)6-4-20/h3-8,11-12,15,19,22,28,30H,2,9-10,13-14,16-17H2,1H3 | UniProtKB/TrEMBL
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211806
(4-(2-(4-fluorophenyl)-7-((isopropyl(methyl)amino)m...)Show SMILES CC(C)N(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCC(C)(C)C)n1 Show InChI InChI=1S/C27H33FN6/c1-18(2)33(6)16-19-12-14-34-23(15-19)32-24(20-7-9-21(28)10-8-20)25(34)22-11-13-29-26(31-22)30-17-27(3,4)5/h7-15,18H,16-17H2,1-6H3,(H,29,30,31) | UniProtKB/TrEMBL
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171702
(1-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol...)Show SMILES OC(COc1ccccc1)CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C29H30FN3O2/c30-24-8-6-23(7-9-24)29-27(21-10-14-31-15-11-21)18-28(32-29)22-12-16-33(17-13-22)19-25(34)20-35-26-4-2-1-3-5-26/h1-11,14-15,18,22,25,32,34H,12-13,16-17,19-20H2 | UniProtKB/TrEMBL
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.660 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374585
(CHEMBL255631)Show SMILES CN1CCOC(CN2CCC(CC2)c2cc(c([nH]2)-c2ccc(F)cc2)-c2ccncc2)C1 |w:5.5| Show InChI InChI=1S/C26H31FN4O/c1-30-14-15-32-23(17-30)18-31-12-8-20(9-13-31)25-16-24(19-6-10-28-11-7-19)26(29-25)21-2-4-22(27)5-3-21/h2-7,10-11,16,20,23,29H,8-9,12-15,17-18H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.670 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171690
(1-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol...)Show SMILES CC(C)OCC(O)CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C26H32FN3O2/c1-18(2)32-17-23(31)16-30-13-9-20(10-14-30)25-15-24(19-7-11-28-12-8-19)26(29-25)21-3-5-22(27)6-4-21/h3-8,11-12,15,18,20,23,29,31H,9-10,13-14,16-17H2,1-2H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.690 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171695
((R)1-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyr...)Show SMILES COCC(O)CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C24H28FN3O2/c1-30-16-21(29)15-28-12-8-18(9-13-28)23-14-22(17-6-10-26-11-7-17)24(27-23)19-2-4-20(25)5-3-19/h2-7,10-11,14,18,21,27,29H,8-9,12-13,15-16H2,1H3 | UniProtKB/TrEMBL
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.690 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171692
(1-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol...)Show SMILES CCC(O)CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C24H28FN3O/c1-2-21(29)16-28-13-9-18(10-14-28)23-15-22(17-7-11-26-12-8-17)24(27-23)19-3-5-20(25)6-4-19/h3-8,11-12,15,18,21,27,29H,2,9-10,13-14,16H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.710 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50168193
(2-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol...)Show SMILES OCCN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C22H24FN3O/c23-19-3-1-18(2-4-19)22-20(16-5-9-24-10-6-16)15-21(25-22)17-7-11-26(12-8-17)13-14-27/h1-6,9-10,15,17,25,27H,7-8,11-14H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.710 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171693
(3-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol...)Show SMILES OCC(O)CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C23H26FN3O2/c24-19-3-1-18(2-4-19)23-21(16-5-9-25-10-6-16)13-22(26-23)17-7-11-27(12-8-17)14-20(29)15-28/h1-6,9-10,13,17,20,26,28-29H,7-8,11-12,14-15H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.710 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50183909
(1-(5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-pyrrol-2...)Show SMILES CC(C)C(N(C)C)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C21H24FN3/c1-14(2)21(25(3)4)19-13-18(15-9-11-23-12-10-15)20(24-19)16-5-7-17(22)8-6-16/h5-14,21,24H,1-4H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.710 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella PKG |
Bioorg Med Chem Lett 16: 2817-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.01.041
BindingDB Entry DOI: 10.7270/Q21V5DK1 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171686
(1-Allyloxy-3-{4-[5-(4-fluoro-phenyl)-4-pyridin-4-y...)Show SMILES OC(COCC=C)CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C26H30FN3O2/c1-2-15-32-18-23(31)17-30-13-9-20(10-14-30)25-16-24(19-7-11-28-12-8-19)26(29-25)21-3-5-22(27)6-4-21/h2-8,11-12,16,20,23,29,31H,1,9-10,13-15,17-18H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
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