Compile Data Set for Download or QSAR

Found 20 hits with Last Name = 'monforte' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50101397 (2-(2,6-Dichloro-phenyl)-3-(6-methyl-pyridin-2-yl)-...) Show SMILES Cc1cccc(n1)N1C(SCC1=O)c1c(Cl)cccc1Cl Show InChI InChI=1S/C15H12Cl2N2OS/c1-9-4-2-7-12(18-9)19-13(20)8-21-15(19)14-10(16)5-3-6-11(14)17/h2-7,15H,8H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50101407 (2-(2,6-Difluoro-phenyl)-3-(4-methyl-pyridin-2-yl)-...) Show SMILES Cc1ccnc(c1)N1C(SCC1=O)c1c(F)cccc1F Show InChI InChI=1S/C15H12F2N2OS/c1-9-5-6-18-12(7-9)19-13(20)8-21-15(19)14-10(16)3-2-4-11(14)17/h2-7,15H,8H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50121354 (2-(2-Fluoro-6-methyl-phenyl)-3-(6-methyl-pyridin-2...) Show SMILES Cc1cccc(n1)N1C(SCC1=O)c1c(C)cccc1F Show InChI InChI=1S/C16H15FN2OS/c1-10-5-3-7-12(17)15(10)16-19(14(20)9-21-16)13-8-4-6-11(2)18-13/h3-8,16H,9H2,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM10237 (6-chloro-1-[(2,6-difluorophenyl)methyl]-2,3-dihydr...) Show SMILES Fc1cccc(F)c1Cn1c2cc(Cl)ccc2[nH]c1=O Show InChI InChI=1S/C14H9ClF2N2O/c15-8-4-5-12-13(6-8)19(14(20)18-12)7-9-10(16)2-1-3-11(9)17/h1-6H,7H2,(H,18,20)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.86E+3	n/a	n/a	n/a	n/a	7.5	37
Universita di Messina					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 48: 3433-7 (2005) Article DOI: 10.1021/jm049279a BindingDB Entry DOI: 10.7270/Q27D2SC4
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50101404 (2-(2,6-Difluoro-phenyl)-3-(6-methyl-pyridin-2-yl)-...) Show SMILES Cc1cccc(n1)N1C(SCC1=O)c1c(F)cccc1F Show InChI InChI=1S/C15H12F2N2OS/c1-9-4-2-7-12(18-9)19-13(20)8-21-15(19)14-10(16)5-3-6-11(14)17/h2-7,15H,8H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50121350 (2-(2-Chloro-6-fluoro-phenyl)-3-(4-methyl-pyridin-2...) Show SMILES Cc1ccnc(c1)N1C(SCC1=O)c1c(F)cccc1Cl Show InChI InChI=1S/C15H12ClFN2OS/c1-9-5-6-18-12(7-9)19-13(20)8-21-15(19)14-10(16)3-2-4-11(14)17/h2-7,15H,8H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50121357 (2-(2,6-Difluoro-phenyl)-3-(4,6-dimethyl-pyridin-2-...) Show SMILES Cc1cc(C)nc(c1)N1C(SCC1=O)c1c(F)cccc1F Show InChI InChI=1S/C16H14F2N2OS/c1-9-6-10(2)19-13(7-9)20-14(21)8-22-16(20)15-11(17)4-3-5-12(15)18/h3-7,16H,8H2,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM10243 (6-chloro-1-(naphthalen-2-ylmethyl)-2,3-dihydro-1H-...) Show SMILES Clc1ccc2[nH]c(=O)n(Cc3ccc4ccccc4c3)c2c1 Show InChI InChI=1S/C18H13ClN2O/c19-15-7-8-16-17(10-15)21(18(22)20-16)11-12-5-6-13-3-1-2-4-14(13)9-12/h1-10H,11H2,(H,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	7.5	37
Universita di Messina					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 48: 3433-7 (2005) Article DOI: 10.1021/jm049279a BindingDB Entry DOI: 10.7270/Q27D2SC4
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM10240 (6-chloro-1-[(2,6-dichlorophenyl)methyl]-2,3-dihydr...) Show SMILES Clc1ccc2[nH]c(=O)n(Cc3c(Cl)cccc3Cl)c2c1 Show InChI InChI=1S/C14H9Cl3N2O/c15-8-4-5-12-13(6-8)19(14(20)18-12)7-9-10(16)2-1-3-11(9)17/h1-6H,7H2,(H,18,20)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	7.5	37
Universita di Messina					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 48: 3433-7 (2005) Article DOI: 10.1021/jm049279a BindingDB Entry DOI: 10.7270/Q27D2SC4
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM10242 (6-chloro-1-(naphthalen-1-ylmethyl)-2,3-dihydro-1H-...) Show SMILES Clc1ccc2[nH]c(=O)n(Cc3cccc4ccccc34)c2c1 Show InChI InChI=1S/C18H13ClN2O/c19-14-8-9-16-17(10-14)21(18(22)20-16)11-13-6-3-5-12-4-1-2-7-15(12)13/h1-10H,11H2,(H,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.27E+4	n/a	n/a	n/a	n/a	7.5	37
Universita di Messina					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 48: 3433-7 (2005) Article DOI: 10.1021/jm049279a BindingDB Entry DOI: 10.7270/Q27D2SC4
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50121347 (CHEMBL625 | THIABENDAZOLE) Show SMILES c1nc(cs1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.46E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM10241 (6-chloro-1-{[4-(propan-2-yl)phenyl]methyl}-2,3-dih...) Show SMILES CC(C)c1ccc(Cn2c3cc(Cl)ccc3[nH]c2=O)cc1 Show InChI InChI=1S/C17H17ClN2O/c1-11(2)13-5-3-12(4-6-13)10-20-16-9-14(18)7-8-15(16)19-17(20)21/h3-9,11H,10H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	7.5	37
Universita di Messina					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 48: 3433-7 (2005) Article DOI: 10.1021/jm049279a BindingDB Entry DOI: 10.7270/Q27D2SC4
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM10239 (5-chloro-3-[(2,6-difluorophenyl)methyl]-2,3-dihydr...) Show SMILES Fc1cccc(F)c1Cn1c2cc(Cl)ccc2oc1=O Show InChI InChI=1S/C14H8ClF2NO2/c15-8-4-5-13-12(6-8)18(14(19)20-13)7-9-10(16)2-1-3-11(9)17/h1-6H,7H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	7.5	37
Universita di Messina					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 48: 3433-7 (2005) Article DOI: 10.1021/jm049279a BindingDB Entry DOI: 10.7270/Q27D2SC4
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM10245 (3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....) Show SMILES Fc1cccc(F)c1C1SCc2nc3ccccc3n12 Show InChI InChI=1S/C15H10F2N2S/c16-9-4-3-5-10(17)14(9)15-19-12-7-2-1-6-11(12)18-13(19)8-20-15/h1-7,15H,8H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.46E+4	n/a	n/a	n/a	n/a	7.5	37
Universita di Messina					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 48: 3433-7 (2005) Article DOI: 10.1021/jm049279a BindingDB Entry DOI: 10.7270/Q27D2SC4
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50121352 (2-(2-Chloro-6-methyl-phenyl)-3-(5-methyl-pyridin-2...) Show SMILES Cc1ccc(nc1)N1C(SCC1=O)c1c(C)cccc1Cl Show InChI InChI=1S/C16H15ClN2OS/c1-10-6-7-13(18-8-10)19-14(20)9-21-16(19)15-11(2)4-3-5-12(15)17/h3-8,16H,9H2,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM10244 (6-chloro-1-(cyclohexylmethyl)-2,3-dihydro-1H-1,3-b...) Show SMILES Clc1ccc2[nH]c(=O)n(CC3CCCCC3)c2c1 Show InChI InChI=1S/C14H17ClN2O/c15-11-6-7-12-13(8-11)17(14(18)16-12)9-10-4-2-1-3-5-10/h6-8,10H,1-5,9H2,(H,16,18)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	7.5	37
Universita di Messina					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 48: 3433-7 (2005) Article DOI: 10.1021/jm049279a BindingDB Entry DOI: 10.7270/Q27D2SC4
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50121351 (3-(5-Bromo-pyridin-2-yl)-2-(2,6-dichloro-phenyl)-t...) Show SMILES Clc1cccc(Cl)c1C1SCC(=O)N1c1ccc(Br)cn1 Show InChI InChI=1S/C14H9BrCl2N2OS/c15-8-4-5-11(18-6-8)19-12(20)7-21-14(19)13-9(16)2-1-3-10(13)17/h1-6,14H,7H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM10238 (5-chloro-1-[(2,6-difluorophenyl)methyl]-2,3-dihydr...) Show SMILES Fc1cccc(F)c1Cn1c2ccc(Cl)cc2[nH]c1=O Show InChI InChI=1S/C14H9ClF2N2O/c15-8-4-5-13-12(6-8)18-14(20)19(13)7-9-10(16)2-1-3-11(9)17/h1-6H,7H2,(H,18,20)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	7.5	37
Universita di Messina					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 48: 3433-7 (2005) Article DOI: 10.1021/jm049279a BindingDB Entry DOI: 10.7270/Q27D2SC4
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50121356 (3-(5-Bromo-pyridin-2-yl)-2-(2,6-difluoro-phenyl)-t...) Show SMILES Fc1cccc(F)c1C1SCC(=O)N1c1ccc(Br)cn1 Show InChI InChI=1S/C14H9BrF2N2OS/c15-8-4-5-11(18-6-8)19-12(20)7-21-14(19)13-9(16)2-1-3-10(13)17/h1-6,14H,7H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50121353 (3-(5-Chloro-pyridin-2-yl)-2-(2,6-difluoro-phenyl)-...) Show SMILES Fc1cccc(F)c1C1SCC(=O)N1c1ccc(Cl)cn1 Show InChI InChI=1S/C14H9ClF2N2OS/c15-8-4-5-11(18-6-8)19-12(20)7-21-14(19)13-9(16)2-1-3-10(13)17/h1-6,14H,7H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair