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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Histone deacetylase (Homo sapiens (Human)) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Wonkwang University Curated by ChEMBL | Assay Description Inhibition of HDAC in HeLa cells | Bioorg Med Chem Lett 17: 4753-5 (2007) Article DOI: 10.1016/j.bmcl.2007.06.060 BindingDB Entry DOI: 10.7270/Q2FJ2KJ4 | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| 72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50310255 (CHEMBL592228 | epicatechin-(4beta-6)-epicatechin-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Wonkwang University Sanbon Medical Center Curated by ChEMBL | Assay Description Inhibition of human rheumatoid synovial fibroblasts gelatinase A after 30 mins by fluorescence plate reader | Bioorg Med Chem Lett 20: 991-3 (2010) Article DOI: 10.1016/j.bmcl.2009.12.059 BindingDB Entry DOI: 10.7270/Q2NP24J0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase (Homo sapiens (Human)) | BDBM50476976 (CHEBI:8329 | Pomiferin) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wonkwang University Curated by ChEMBL | Assay Description Inhibition of HDAC in HeLa cells | Bioorg Med Chem Lett 17: 4753-5 (2007) Article DOI: 10.1016/j.bmcl.2007.06.060 BindingDB Entry DOI: 10.7270/Q2FJ2KJ4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM232202 ((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For the binding assay, aliquots of receptor membranes, 0.25 nM [3H]8-OH-DPAT (8-hydroxy-2-(di-N-propylamino)tetralin, 154.3 Ci/mM; New England Nuclea... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM232203 ((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For the binding assay, aliquots of receptor membranes, 0.25 nM [3H]8-OH-DPAT (8-hydroxy-2-(di-N-propylamino)tetralin, 154.3 Ci/mM; New England Nuclea... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50310255 (CHEMBL592228 | epicatechin-(4beta-6)-epicatechin-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wonkwang University Sanbon Medical Center Curated by ChEMBL | Assay Description Inhibition of human neutrophils gelatinase B after 30 mins by fluorescence plate reader | Bioorg Med Chem Lett 20: 991-3 (2010) Article DOI: 10.1016/j.bmcl.2009.12.059 BindingDB Entry DOI: 10.7270/Q2NP24J0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM232204 (3,4,5-Trimethoxycinnamic acid (TMCA)) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ewha Womans University | Assay Description Frozen membranes from a stable CHO-K1 cell line expressing the human recombinant 5-HT2C receptor (PerkinElmer) were used. For the binding assay, [3H]... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM232201 ((E)-N-Hexyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For the binding assay, aliquots of receptor membranes, 0.25 nM [3H]8-OH-DPAT (8-hydroxy-2-(di-N-propylamino)tetralin, 154.3 Ci/mM; New England Nuclea... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM232203 ((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ewha Womans University | Assay Description Frozen membranes from a stable CHO-K1 cell line expressing the human recombinant 5-HT2C receptor (PerkinElmer) were used. For the binding assay, [3H]... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM232200 ((E)-N-Butyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For the binding assay, aliquots of receptor membranes, 0.25 nM [3H]8-OH-DPAT (8-hydroxy-2-(di-N-propylamino)tetralin, 154.3 Ci/mM; New England Nuclea... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM232203 ((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM232198 ((E)-N-Methyl-3-(3,4,5-trimethoxyphenyl) acrylamide...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For the binding assay, aliquots of receptor membranes, 0.25 nM [3H]8-OH-DPAT (8-hydroxy-2-(di-N-propylamino)tetralin, 154.3 Ci/mM; New England Nuclea... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM232199 ((E)-N-Allyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For the binding assay, aliquots of receptor membranes, 0.25 nM [3H]8-OH-DPAT (8-hydroxy-2-(di-N-propylamino)tetralin, 154.3 Ci/mM; New England Nuclea... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase (Homo sapiens (Human)) | BDBM50442397 (OSAJIN) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wonkwang University Curated by ChEMBL | Assay Description Inhibition of HDAC in HeLa cells | Bioorg Med Chem Lett 17: 4753-5 (2007) Article DOI: 10.1016/j.bmcl.2007.06.060 BindingDB Entry DOI: 10.7270/Q2FJ2KJ4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM232203 ((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM232203 ((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ewha Womans University | Assay Description For serotonin 5-HT2A binding, an aliquot of frozen membrane from a CHO-K1 cell line expressing the human recombinant 5-HT2A receptor (PerkinElmer) an... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM232204 (3,4,5-Trimethoxycinnamic acid (TMCA)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For the binding assay, aliquots of receptor membranes, 0.25 nM [3H]8-OH-DPAT (8-hydroxy-2-(di-N-propylamino)tetralin, 154.3 Ci/mM; New England Nuclea... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50170723 (1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 7.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wonkwang University Sanbon Medical Center Curated by ChEMBL | Assay Description Inhibition of human rheumatoid synovial fibroblasts gelatinase A after 30 mins by fluorescence plate reader | Bioorg Med Chem Lett 20: 991-3 (2010) Article DOI: 10.1016/j.bmcl.2009.12.059 BindingDB Entry DOI: 10.7270/Q2NP24J0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50170723 (1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 7.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wonkwang University Sanbon Medical Center Curated by ChEMBL | Assay Description Inhibition of human neutrophils gelatinase B after 30 mins by fluorescence plate reader | Bioorg Med Chem Lett 20: 991-3 (2010) Article DOI: 10.1016/j.bmcl.2009.12.059 BindingDB Entry DOI: 10.7270/Q2NP24J0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM232202 ((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ewha Womans University | Assay Description Frozen membranes from a stable CHO-K1 cell line expressing the human recombinant 5-HT2C receptor (PerkinElmer) were used. For the binding assay, [3H]... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM232199 ((E)-N-Allyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM232200 ((E)-N-Butyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM232201 ((E)-N-Hexyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM232202 ((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM232201 ((E)-N-Hexyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ewha Womans University | Assay Description For serotonin 5-HT2A binding, an aliquot of frozen membrane from a CHO-K1 cell line expressing the human recombinant 5-HT2A receptor (PerkinElmer) an... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM232204 (3,4,5-Trimethoxycinnamic acid (TMCA)) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM232198 ((E)-N-Methyl-3-(3,4,5-trimethoxyphenyl) acrylamide...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM232199 ((E)-N-Allyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM232200 ((E)-N-Butyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM232201 ((E)-N-Hexyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM232202 ((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM232204 (3,4,5-Trimethoxycinnamic acid (TMCA)) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM232200 ((E)-N-Butyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ewha Womans University | Assay Description For serotonin 5-HT2A binding, an aliquot of frozen membrane from a CHO-K1 cell line expressing the human recombinant 5-HT2A receptor (PerkinElmer) an... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM232198 ((E)-N-Methyl-3-(3,4,5-trimethoxyphenyl) acrylamide...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM232202 ((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ewha Womans University | Assay Description For serotonin 5-HT2A binding, an aliquot of frozen membrane from a CHO-K1 cell line expressing the human recombinant 5-HT2A receptor (PerkinElmer) an... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM232201 ((E)-N-Hexyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ewha Womans University | Assay Description Frozen membranes from a stable CHO-K1 cell line expressing the human recombinant 5-HT2C receptor (PerkinElmer) were used. For the binding assay, [3H]... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM232200 ((E)-N-Butyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ewha Womans University | Assay Description Frozen membranes from a stable CHO-K1 cell line expressing the human recombinant 5-HT2C receptor (PerkinElmer) were used. For the binding assay, [3H]... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM232204 (3,4,5-Trimethoxycinnamic acid (TMCA)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ewha Womans University | Assay Description For serotonin 5-HT2A binding, an aliquot of frozen membrane from a CHO-K1 cell line expressing the human recombinant 5-HT2A receptor (PerkinElmer) an... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM232198 ((E)-N-Methyl-3-(3,4,5-trimethoxyphenyl) acrylamide...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ewha Womans University | Assay Description Frozen membranes from a stable CHO-K1 cell line expressing the human recombinant 5-HT2C receptor (PerkinElmer) were used. For the binding assay, [3H]... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM232199 ((E)-N-Allyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ewha Womans University | Assay Description Frozen membranes from a stable CHO-K1 cell line expressing the human recombinant 5-HT2C receptor (PerkinElmer) were used. For the binding assay, [3H]... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM232198 ((E)-N-Methyl-3-(3,4,5-trimethoxyphenyl) acrylamide...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ewha Womans University | Assay Description For serotonin 5-HT2A binding, an aliquot of frozen membrane from a CHO-K1 cell line expressing the human recombinant 5-HT2A receptor (PerkinElmer) an... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM232199 ((E)-N-Allyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ewha Womans University | Assay Description For serotonin 5-HT2A binding, an aliquot of frozen membrane from a CHO-K1 cell line expressing the human recombinant 5-HT2A receptor (PerkinElmer) an... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50310254 (CHEMBL592329 | epicatechin-(4beta-8)-epicatechin-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wonkwang University Sanbon Medical Center Curated by ChEMBL | Assay Description Inhibition of human rheumatoid synovial fibroblasts gelatinase A after 30 mins by fluorescence plate reader | Bioorg Med Chem Lett 20: 991-3 (2010) Article DOI: 10.1016/j.bmcl.2009.12.059 BindingDB Entry DOI: 10.7270/Q2NP24J0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50310254 (CHEMBL592329 | epicatechin-(4beta-8)-epicatechin-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.73E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wonkwang University Sanbon Medical Center Curated by ChEMBL | Assay Description Inhibition of human neutrophils gelatinase B after 30 mins by fluorescence plate reader | Bioorg Med Chem Lett 20: 991-3 (2010) Article DOI: 10.1016/j.bmcl.2009.12.059 BindingDB Entry DOI: 10.7270/Q2NP24J0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50240460 ((2R,3R,4R,2'R,3'R,4'S,2''R,3''R)-2,2',2''-Tris-(3,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wonkwang University Sanbon Medical Center Curated by ChEMBL | Assay Description Inhibition of human rheumatoid synovial fibroblasts gelatinase A after 30 mins by fluorescence plate reader | Bioorg Med Chem Lett 20: 991-3 (2010) Article DOI: 10.1016/j.bmcl.2009.12.059 BindingDB Entry DOI: 10.7270/Q2NP24J0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50310256 (CHEMBL592373 | epicatechin-(4beta-8)-epicatechin-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.92E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wonkwang University Sanbon Medical Center Curated by ChEMBL | Assay Description Inhibition of human neutrophils gelatinase B after 30 mins by fluorescence plate reader | Bioorg Med Chem Lett 20: 991-3 (2010) Article DOI: 10.1016/j.bmcl.2009.12.059 BindingDB Entry DOI: 10.7270/Q2NP24J0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50310256 (CHEMBL592373 | epicatechin-(4beta-8)-epicatechin-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wonkwang University Sanbon Medical Center Curated by ChEMBL | Assay Description Inhibition of human rheumatoid synovial fibroblasts gelatinase A after 30 mins by fluorescence plate reader | Bioorg Med Chem Lett 20: 991-3 (2010) Article DOI: 10.1016/j.bmcl.2009.12.059 BindingDB Entry DOI: 10.7270/Q2NP24J0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50240460 ((2R,3R,4R,2'R,3'R,4'S,2''R,3''R)-2,2',2''-Tris-(3,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wonkwang University Sanbon Medical Center Curated by ChEMBL | Assay Description Inhibition of human neutrophils gelatinase B after 30 mins by fluorescence plate reader | Bioorg Med Chem Lett 20: 991-3 (2010) Article DOI: 10.1016/j.bmcl.2009.12.059 BindingDB Entry DOI: 10.7270/Q2NP24J0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
