Reaction Details |
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Target | 5-hydroxytryptamine receptor 6 |
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Ligand | BDBM232202 |
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Substrate/Competitor | n/a |
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Meas. Tech. | [3H] LSD Binding Assay |
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pH | 7.4±n/a |
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Temperature | 300.15±n/a K |
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IC50 | >1.0e+4±n/a nM |
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Comments | extracted |
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Citation | Jung, JC; Min, D; Kim, H; Jang, S; Lee, Y; Park, W; Khan, IA; Moon, HI; Jung, M; Oh, S Design, synthesis, and biological evaluation of 3,4,5-trimethoxyphenyl acrylamides as antinarcotic agents. J Enzyme Inhib Med Chem25:38-43 (2010) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 6 |
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Name: | 5-hydroxytryptamine receptor 6 |
Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 46968.43 |
Organism: | Homo sapiens (Human) |
Description: | P50406 |
Residue: | 440 |
Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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BDBM232202 |
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n/a |
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Name | BDBM232202 |
Synonyms: | (E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide (1e) |
Type | Small organic molecule |
Emp. Form. | C20H31NO4 |
Mol. Mass. | 349.4644 |
SMILES | CCCCCCCCNC(=O)\C=C\c1cc(OC)c(OC)c(OC)c1 |
Structure |
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