| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
|---|
| Ligand | BDBM232204 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | [3H]Ketanserin Binding Assay |
|---|
| pH | 7.4±n/a |
|---|
| IC50 | >1.0e+4±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Jung, JC; Min, D; Kim, H; Jang, S; Lee, Y; Park, W; Khan, IA; Moon, HI; Jung, M; Oh, S Design, synthesis, and biological evaluation of 3,4,5-trimethoxyphenyl acrylamides as antinarcotic agents. J Enzyme Inhib Med Chem25:38-43 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 2A |
|---|
| Name: | 5-hydroxytryptamine receptor 2A |
|---|
| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A |
|---|
| Type: | undefined |
|---|
| Mol. Mass.: | 52607.65 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P28223 |
|---|
| Residue: | 471 |
|---|
| Sequence: | MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
|
|
|
|---|
| BDBM232204 |
|---|
| n/a |
|---|
| Name | BDBM232204 |
|---|
| Synonyms: | 3,4,5-Trimethoxycinnamic acid (TMCA) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H14O5 |
|---|
| Mol. Mass. | 238.2366 |
|---|
| SMILES | COc1cc(\C=C\C(O)=O)cc(OC)c1OC |
|---|
| Structure | 
|
|---|
Search and Browse
