Compile Data Set for Download or QSAR

Found 33 hits with Last Name = 'navarro' and Initial = 'ec'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heparanase (Homo sapiens (Human))	BDBM50175932 (1,3-bis-[4-(5,6-dimethyl-1H-benzoimidazol-2-yl)phe...) Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(NC(=O)Nc2ccc(cc2)-c2nc3cc(C)c(C)cc3[nH]2)cc1 Show InChI InChI=1S/C31H28N6O/c1-17-13-25-26(14-18(17)2)35-29(34-25)21-5-9-23(10-6-21)32-31(38)33-24-11-7-22(8-12-24)30-36-27-15-19(3)20(4)16-28(27)37-30/h5-16H,1-4H3,(H,34,35)(H,36,37)(H2,32,33,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175931 (1-(4-(1H-benzo[d]imidazol-2-yl)phenyl)-3-(4-(7-met...) Show SMILES Cc1cccc2[nH]c(nc12)-c1ccc(NC(=O)Nc2ccc(cc2)-c2nc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C28H22N6O/c1-17-5-4-8-24-25(17)34-27(33-24)19-11-15-21(16-12-19)30-28(35)29-20-13-9-18(10-14-20)26-31-22-6-2-3-7-23(22)32-26/h2-16H,1H3,(H,31,32)(H,33,34)(H2,29,30,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175936 (1,3-bis(4-(6-methyl-1H-benzo[d]imidazol-2-yl)pheny...) Show SMILES Cc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)Nc2ccc(cc2)-c2nc3ccc(C)cc3[nH]2)cc1 Show InChI InChI=1S/C29H24N6O/c1-17-3-13-23-25(15-17)34-27(32-23)19-5-9-21(10-6-19)30-29(36)31-22-11-7-20(8-12-22)28-33-24-14-4-18(2)16-26(24)35-28/h3-16H,1-2H3,(H,32,34)(H,33,35)(H2,30,31,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175938 (1,3-bis(4-(7-methyl-1H-benzo[d]imidazol-2-yl)pheny...) Show SMILES Cc1cccc2[nH]c(nc12)-c1ccc(NC(=O)Nc2ccc(cc2)-c2nc3c(C)cccc3[nH]2)cc1 Show InChI InChI=1S/C29H24N6O/c1-17-5-3-7-23-25(17)34-27(32-23)19-9-13-21(14-10-19)30-29(36)31-22-15-11-20(12-16-22)28-33-24-8-4-6-18(2)26(24)35-28/h3-16H,1-2H3,(H,32,34)(H,33,35)(H2,30,31,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175811 (CHEMBL200215 | N-(4-{[4-(1H-benzoimidazol-2-yl)phe...) Show SMILES COc1ccc(cc1Br)C(=O)Nc1ccc(CNc2ccc(cc2)-c2nc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C28H23BrN4O2/c1-35-26-15-10-20(16-23(26)29)28(34)31-22-11-6-18(7-12-22)17-30-21-13-8-19(9-14-21)27-32-24-4-2-3-5-25(24)33-27/h2-16,30H,17H2,1H3,(H,31,34)(H,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175939 (1,3-bis-[4-(1H-benzoimidazol-2-yl)phenyl]urea | CH...) Show SMILES O=C(Nc1ccc(cc1)-c1nc2ccccc2[nH]1)Nc1ccc(cc1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C27H20N6O/c34-27(28-19-13-9-17(10-14-19)25-30-21-5-1-2-6-22(21)31-25)29-20-15-11-18(12-16-20)26-32-23-7-3-4-8-24(23)33-26/h1-16H,(H,30,31)(H,32,33)(H2,28,29,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175813 (CHEMBL200831 | N-(4-{[5-(1H-benzoimidazol-2-yl)-py...) Show SMILES COc1ccc(cc1Br)C(=O)Nc1ccc(CNc2ccc(cn2)-c2nc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C27H22BrN5O2/c1-35-24-12-8-18(14-21(24)28)27(34)31-20-10-6-17(7-11-20)15-29-25-13-9-19(16-30-25)26-32-22-4-2-3-5-23(22)33-26/h2-14,16H,15H2,1H3,(H,29,30)(H,31,34)(H,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175937 (1,3-bis(4-(7-methoxy-1H-benzo[d]imidazol-2-yl)phen...) Show SMILES COc1cccc2[nH]c(nc12)-c1ccc(NC(=O)Nc2ccc(cc2)-c2nc3c(OC)cccc3[nH]2)cc1 Show InChI InChI=1S/C29H24N6O3/c1-37-23-7-3-5-21-25(23)34-27(32-21)17-9-13-19(14-10-17)30-29(36)31-20-15-11-18(12-16-20)28-33-22-6-4-8-24(38-2)26(22)35-28/h3-16H,1-2H3,(H,32,34)(H,33,35)(H2,30,31,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175933 (1,3-bis(4-(1H-imidazo[4,5-c]pyridin-2-yl)phenyl)ur...) Show SMILES O=C(Nc1ccc(cc1)-c1nc2ccncc2[nH]1)Nc1ccc(cc1)-c1nc2ccncc2[nH]1 Show InChI InChI=1S/C25H18N8O/c34-25(28-17-5-1-15(2-6-17)23-30-19-9-11-26-13-21(19)32-23)29-18-7-3-16(4-8-18)24-31-20-10-12-27-14-22(20)33-24/h1-14H,(H,30,32)(H,31,33)(H2,28,29,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175823 (CHEMBL199569 | N-{4-[4-(1H-benzoimidazol-2-yl)-phe...) Show SMILES COc1ccc(cc1Br)C(=O)Nc1ccc(cc1)C(=O)Nc1ccc(cc1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C28H21BrN4O3/c1-36-25-15-10-19(16-22(25)29)28(35)31-21-13-8-18(9-14-21)27(34)30-20-11-6-17(7-12-20)26-32-23-4-2-3-5-24(23)33-26/h2-16H,1H3,(H,30,34)(H,31,35)(H,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175822 (1-(4-(1H-benzo[d]imidazol-2-yl)phenyl)-3-(3-bromo-...) Show SMILES COc1ccc(NC(=O)Nc2ccc(cc2)-c2nc3ccccc3[nH]2)cc1Br Show InChI InChI=1S/C21H17BrN4O2/c1-28-19-11-10-15(12-16(19)22)24-21(27)23-14-8-6-13(7-9-14)20-25-17-4-2-3-5-18(17)26-20/h2-12H,1H3,(H,25,26)(H2,23,24,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175821 (CHEMBL200399 | N-(4-((4-(1H-imidazo[4,5-c]pyridin-...) Show SMILES COc1ccc(cc1Br)C(=O)Nc1ccc(CNc2ccc(cc2)-c2nc3ccncc3[nH]2)cc1 Show InChI InChI=1S/C27H22BrN5O2/c1-35-25-11-6-19(14-22(25)28)27(34)31-21-7-2-17(3-8-21)15-30-20-9-4-18(5-10-20)26-32-23-12-13-29-16-24(23)33-26/h2-14,16,30H,15H2,1H3,(H,31,34)(H,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175934 (1-(4-(1H-benzo[d]imidazol-2-yl)phenyl)-3-(4-(1H-im...) Show SMILES O=C(Nc1ccc(cc1)-c1nc2ccccc2[nH]1)Nc1ccc(cc1)-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C26H19N7O/c34-26(28-18-11-7-16(8-12-18)23-30-20-4-1-2-5-21(20)31-23)29-19-13-9-17(10-14-19)24-32-22-6-3-15-27-25(22)33-24/h1-15H,(H,30,31)(H,27,32,33)(H2,28,29,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175803 (3-bromo-N-(4-(5,6-dimethyl-1H-benzo[d]imidazol-2-y...) Show SMILES CCOc1ccc(cc1Br)C(=O)Nc1ccc(cc1)-c1nc2cc(C)c(C)cc2[nH]1 Show InChI InChI=1S/C24H22BrN3O2/c1-4-30-22-10-7-17(13-19(22)25)24(29)26-18-8-5-16(6-9-18)23-27-20-11-14(2)15(3)12-21(20)28-23/h5-13H,4H2,1-3H3,(H,26,29)(H,27,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175930 (1-(4-(1H-benzo[d]imidazol-2-yl)phenyl)-3-(4-(7-met...) Show SMILES COc1cccc2[nH]c(nc12)-c1ccc(NC(=O)Nc2ccc(cc2)-c2nc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C28H22N6O2/c1-36-24-8-4-7-23-25(24)34-27(33-23)18-11-15-20(16-12-18)30-28(35)29-19-13-9-17(10-14-19)26-31-21-5-2-3-6-22(21)32-26/h2-16H,1H3,(H,31,32)(H,33,34)(H2,29,30,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175819 (CHEMBL200745 | N-(4-(1H-benzo[d]imidazol-2-yl)phen...) Show SMILES CCOc1ccc(cc1Br)C(=O)Nc1ccc(cc1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C22H18BrN3O2/c1-2-28-20-12-9-15(13-17(20)23)22(27)24-16-10-7-14(8-11-16)21-25-18-5-3-4-6-19(18)26-21/h3-13H,2H2,1H3,(H,24,27)(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175807 (3-bromo-N-(4-(4,5-dimethyl-1H-benzo[d]imidazol-2-y...) Show SMILES CCOc1ccc(cc1Br)C(=O)Nc1ccc(cc1)-c1nc2ccc(C)c(C)c2[nH]1 Show InChI InChI=1S/C24H22BrN3O2/c1-4-30-21-12-8-17(13-19(21)25)24(29)26-18-9-6-16(7-10-18)23-27-20-11-5-14(2)15(3)22(20)28-23/h5-13H,4H2,1-3H3,(H,26,29)(H,27,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175825 (3-bromo-4-ethoxy-N-(4-(5-methyl-1H-benzo[d]imidazo...) Show SMILES CCOc1ccc(cc1Br)C(=O)Nc1ccc(cc1)-c1nc2ccc(C)cc2[nH]1 Show InChI InChI=1S/C23H20BrN3O2/c1-3-29-21-11-7-16(13-18(21)24)23(28)25-17-8-5-15(6-9-17)22-26-19-10-4-14(2)12-20(19)27-22/h4-13H,3H2,1-2H3,(H,25,28)(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175810 (CHEMBL199576 | N-(4-(1H-benzo[d]imidazol-2-yl)phen...) Show SMILES CCCOc1ccc(cc1Br)C(=O)Nc1ccc(cc1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C23H20BrN3O2/c1-2-13-29-21-12-9-16(14-18(21)24)23(28)25-17-10-7-15(8-11-17)22-26-19-5-3-4-6-20(19)27-22/h3-12,14H,2,13H2,1H3,(H,25,28)(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175824 (3-bromo-4-ethoxy-N-(4-(4-methyl-1H-benzo[d]imidazo...) Show SMILES CCOc1ccc(cc1Br)C(=O)Nc1ccc(cc1)-c1nc2c(C)cccc2[nH]1 Show InChI InChI=1S/C23H20BrN3O2/c1-3-29-20-12-9-16(13-18(20)24)23(28)25-17-10-7-15(8-11-17)22-26-19-6-4-5-14(2)21(19)27-22/h4-13H,3H2,1-2H3,(H,25,28)(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175806 (3-bromo-N-(4-(4,7-dimethyl-1H-benzo[d]imidazol-2-y...) Show SMILES CCOc1ccc(cc1Br)C(=O)Nc1ccc(cc1)-c1nc2c(C)ccc(C)c2[nH]1 Show InChI InChI=1S/C24H22BrN3O2/c1-4-30-20-12-9-17(13-19(20)25)24(29)26-18-10-7-16(8-11-18)23-27-21-14(2)5-6-15(3)22(21)28-23/h5-13H,4H2,1-3H3,(H,26,29)(H,27,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175935 (1,3-bis(4-(1H-imidazo[4,5-b]pyridin-2-yl)phenyl)ur...) Show SMILES O=C(Nc1ccc(cc1)-c1nc2ncccc2[nH]1)Nc1ccc(cc1)-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C25H18N8O/c34-25(28-17-9-5-15(6-10-17)21-30-19-3-1-13-26-23(19)32-21)29-18-11-7-16(8-12-18)22-31-20-4-2-14-27-24(20)33-22/h1-14H,(H,26,30,32)(H,27,31,33)(H2,28,29,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175812 (CHEMBL200333 | N-(4-(1H-benzo[d]imidazol-2-yl)phen...) Show SMILES COc1ccc(cc1Br)C(=O)Nc1ccc(cc1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C21H16BrN3O2/c1-27-19-11-8-14(12-16(19)22)21(26)23-15-9-6-13(7-10-15)20-24-17-4-2-3-5-18(17)25-20/h2-12H,1H3,(H,23,26)(H,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175815 (CHEMBL371444 | N-(4-(1H-benzo[d]imidazol-2-yl)phen...) Show SMILES COc1ccc(cc1-c1cccnc1)C(=O)Nc1ccc(cc1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C26H20N4O2/c1-32-24-13-10-18(15-21(24)19-5-4-14-27-16-19)26(31)28-20-11-8-17(9-12-20)25-29-22-6-2-3-7-23(22)30-25/h2-16H,1H3,(H,28,31)(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175805 (CHEMBL200649 | N-(4-(1H-benzo[d]imidazol-2-yl)phen...) Show SMILES COc1ccc(cc1-c1ccc2[nH]ncc2c1)C(=O)Nc1ccc(cc1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C28H21N5O2/c1-35-26-13-9-19(15-22(26)18-8-12-23-20(14-18)16-29-33-23)28(34)30-21-10-6-17(7-11-21)27-31-24-4-2-3-5-25(24)32-27/h2-16H,1H3,(H,29,33)(H,30,34)(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175816 (4'-hydroxy-6-methoxy-biphenyl-3-carboxylic acid [4...) Show SMILES COc1ccc(cc1-c1ccc(O)cc1)C(=O)Nc1ccc(cc1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C27H21N3O3/c1-33-25-15-10-19(16-22(25)17-8-13-21(31)14-9-17)27(32)28-20-11-6-18(7-12-20)26-29-23-4-2-3-5-24(23)30-26/h2-16,31H,1H3,(H,28,32)(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175809 (CHEMBL200246 | N-(4-(1H-benzo[d]imidazol-2-yl)phen...) Show SMILES COc1ccc(CC(=O)Nc2ccc(cc2)-c2nc3ccccc3[nH]2)cc1Br Show InChI InChI=1S/C22H18BrN3O2/c1-28-20-11-6-14(12-17(20)23)13-21(27)24-16-9-7-15(8-10-16)22-25-18-4-2-3-5-19(18)26-22/h2-12H,13H2,1H3,(H,24,27)(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175820 (CHEMBL200245 | N-(3-bromo-4-methoxybenzyl)-4-(1H-b...) Show SMILES COc1ccc(CNc2ccc(cc2)-c2nc3ccccc3[nH]2)cc1Br Show InChI InChI=1S/C21H18BrN3O/c1-26-20-11-6-14(12-17(20)22)13-23-16-9-7-15(8-10-16)21-24-18-4-2-3-5-19(18)25-21/h2-12,23H,13H2,1H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175818 (4-(1H-benzo[d]imidazol-2-yl)-N-(3-bromo-4-methoxyp...) Show SMILES COc1ccc(NC(=O)c2ccc(cc2)-c2nc3ccccc3[nH]2)cc1Br Show InChI InChI=1S/C21H16BrN3O2/c1-27-19-11-10-15(12-16(19)22)23-21(26)14-8-6-13(7-9-14)20-24-17-4-2-3-5-18(17)25-20/h2-12H,1H3,(H,23,26)(H,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175804 (CHEMBL199342 | N-(4-(1H-benzo[d]imidazol-2-yl)phen...) Show SMILES COc1ccc(cc1Cl)C(=O)Nc1ccc(cc1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C21H16ClN3O2/c1-27-19-11-8-14(12-16(19)22)21(26)23-15-9-6-13(7-10-15)20-24-17-4-2-3-5-18(17)25-20/h2-12H,1H3,(H,23,26)(H,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175814 (CHEMBL199700 | N-(4-(1H-benzo[d]imidazol-2-yl)phen...) Show SMILES COc1ccc(cc1F)C(=O)Nc1ccc(cc1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C21H16FN3O2/c1-27-19-11-8-14(12-16(19)22)21(26)23-15-9-6-13(7-10-15)20-24-17-4-2-3-5-18(17)25-20/h2-12H,1H3,(H,23,26)(H,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175817 (CHEMBL200936 | N-(4-(1H-benzo[d]imidazol-2-yl)phen...) Show SMILES COc1ccc(cc1Br)C(=O)N(C)c1ccc(cc1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C22H18BrN3O2/c1-26(22(27)15-9-12-20(28-2)17(23)13-15)16-10-7-14(8-11-16)21-24-18-5-3-4-6-19(18)25-21/h3-13H,1-2H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175808 (CHEMBL200859 | N-(4-(1H-benzo[d]imidazol-2-yl)phen...) Show SMILES COc1ccc(cc1Br)S(=O)(=O)Nc1ccc(cc1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C20H16BrN3O3S/c1-27-19-11-10-15(12-16(19)21)28(25,26)24-14-8-6-13(7-9-14)20-22-17-4-2-3-5-18(17)23-20/h2-12,24H,1H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 404-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.070 BindingDB Entry DOI: 10.7270/Q2FJ2G9R
					More data for this Ligand-Target Pair