Compile Data Set for Download or QSAR

Found 83 hits with Last Name = 'paluszcak' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM9914 (3-[(R)-1H-imidazol-1-yl(4-nitrophenyl)methyl]-4H-c...) Show SMILES O=c1c(coc2ccccc12)[C@@H](c1ccc(cc1)N(=O)=O)n1ccnc1 |r| Show InChI InChI=1S/C19H13N3O4/c23-19-15-3-1-2-4-17(15)26-11-16(19)18(21-10-9-20-12-21)13-5-7-14(8-6-13)22(24)25/h1-12,18H/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.4	30
University of Bologna					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...				J Med Chem 48: 7282-9 (2005) Article DOI: 10.1021/jm058042r BindingDB Entry DOI: 10.7270/Q2JS9NN9
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9920 ((S)Fadrozole | 4-[(5S)-5,6,7,8-tetrahydroimidazo[1...) Show SMILES N#Cc1ccc(cc1)[C@@H]1CCCc2cncn12 |r| Show InChI InChI=1S/C14H13N3/c15-8-11-4-6-12(7-5-11)14-3-1-2-13-9-16-10-17(13)14/h4-7,9-10,14H,1-3H2/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	7.4	30
University of Bologna					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...				J Med Chem 48: 7282-9 (2005) Article DOI: 10.1021/jm058042r BindingDB Entry DOI: 10.7270/Q2JS9NN9
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50191598 (3-((1H-imidazol-1-yl)methyl)-2-(4-nitrophenyl)-4H-...) Show SMILES [O-][N+](=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1Cn1ccnc1 Show InChI InChI=1S/C19H13N3O4/c23-18-15-3-1-2-4-17(15)26-19(16(18)11-21-10-9-20-12-21)13-5-7-14(8-6-13)22(24)25/h1-10,12H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50191598 (3-((1H-imidazol-1-yl)methyl)-2-(4-nitrophenyl)-4H-...) Show SMILES [O-][N+](=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1Cn1ccnc1 Show InChI InChI=1S/C19H13N3O4/c23-18-15-3-1-2-4-17(15)26-19(16(18)11-21-10-9-20-12-21)13-5-7-14(8-6-13)22(24)25/h1-10,12H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9916 (3-[(R)-(4-bromophenyl)(1H-imidazol-1-yl)methyl]-4H...) Show SMILES Brc1ccc(cc1)[C@H](c1coc2ccccc2c1=O)n1ccnc1 |r| Show InChI InChI=1S/C19H13BrN2O2/c20-14-7-5-13(6-8-14)18(22-10-9-21-12-22)16-11-24-17-4-2-1-3-15(17)19(16)23/h1-12,18H/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	7.4	30
University of Bologna					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...				J Med Chem 48: 7282-9 (2005) Article DOI: 10.1021/jm058042r BindingDB Entry DOI: 10.7270/Q2JS9NN9
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9475 (4-(1H-Imidazol-1-ylmethyl)-7-phenoxy-2H-chromen-2-...) Show SMILES O=c1cc(Cn2ccnc2)c2ccc(Oc3ccccc3)cc2o1 Show InChI InChI=1S/C19H14N2O3/c22-19-10-14(12-21-9-8-20-13-21)17-7-6-16(11-18(17)24-19)23-15-4-2-1-3-5-15/h1-11,13H,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM8611 (4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...) Show SMILES N#Cc1ccc(cc1)C1CCCc2cncn12 Show InChI InChI=1S/C14H13N3/c15-8-11-4-6-12(7-5-11)14-3-1-2-13-9-16-10-17(13)14/h4-7,9-10,14H,1-3H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50191602 (4'-cyano-3-(imidazolylmethyl)flavone | 4-(3-((1H-i...) Show SMILES O=c1c(Cn2ccnc2)c(oc2ccccc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C20H13N3O2/c21-11-14-5-7-15(8-6-14)20-17(12-23-10-9-22-13-23)19(24)16-3-1-2-4-18(16)25-20/h1-10,13H,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50191602 (4'-cyano-3-(imidazolylmethyl)flavone | 4-(3-((1H-i...) Show SMILES O=c1c(Cn2ccnc2)c(oc2ccccc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C20H13N3O2/c21-11-14-5-7-15(8-6-14)20-17(12-23-10-9-22-13-23)19(24)16-3-1-2-4-18(16)25-20/h1-10,13H,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50191599 (3-((1H-imidazol-1-yl)methyl)-2-phenyl-4H-chromen-4...) Show SMILES O=c1c(Cn2ccnc2)c(oc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C19H14N2O2/c22-18-15-8-4-5-9-17(15)23-19(14-6-2-1-3-7-14)16(18)12-21-11-10-20-13-21/h1-11,13H,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50191599 (3-((1H-imidazol-1-yl)methyl)-2-phenyl-4H-chromen-4...) Show SMILES O=c1c(Cn2ccnc2)c(oc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C19H14N2O2/c22-18-15-8-4-5-9-17(15)23-19(14-6-2-1-3-7-14)16(18)12-21-11-10-20-13-21/h1-11,13H,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9465 (1-(9-Phenyl-9H-fluoren-9-yl)-1H-imidazole | CHEMBL...) Show SMILES c1cn(cn1)C1(c2ccccc2-c2ccccc12)c1ccccc1 Show InChI InChI=1S/C22H16N2/c1-2-8-17(9-3-1)22(24-15-14-23-16-24)20-12-6-4-10-18(20)19-11-5-7-13-21(19)22/h1-16H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50191600 (3-((1H-imidazol-1-yl)methyl)-2-(4-methoxyphenyl)-4...) Show SMILES COc1ccc(cc1)-c1oc2ccccc2c(=O)c1Cn1ccnc1 Show InChI InChI=1S/C20H16N2O3/c1-24-15-8-6-14(7-9-15)20-17(12-22-11-10-21-13-22)19(23)16-4-2-3-5-18(16)25-20/h2-11,13H,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50191600 (3-((1H-imidazol-1-yl)methyl)-2-(4-methoxyphenyl)-4...) Show SMILES COc1ccc(cc1)-c1oc2ccccc2c(=O)c1Cn1ccnc1 Show InChI InChI=1S/C20H16N2O3/c1-24-15-8-6-14(7-9-15)20-17(12-22-11-10-21-13-22)19(23)16-4-2-3-5-18(16)25-20/h2-11,13H,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9915 (3-[(S)-1H-imidazol-1-yl(4-nitrophenyl)methyl]-4H-c...) Show SMILES O=c1c(coc2ccccc12)[C@H](c1ccc(cc1)N(=O)=O)n1ccnc1 |r| Show InChI InChI=1S/C19H13N3O4/c23-19-15-3-1-2-4-17(15)26-11-16(19)18(21-10-9-20-12-21)13-5-7-14(8-6-13)22(24)25/h1-12,18H/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	7.4	30
University of Bologna					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...				J Med Chem 48: 7282-9 (2005) Article DOI: 10.1021/jm058042r BindingDB Entry DOI: 10.7270/Q2JS9NN9
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9483 (3-(1H-Imidazol-1-ylmethyl)-7-methoxy-4-phenyl-2H-c...) Show SMILES COc1ccc2c(-c3ccccc3)c(Cn3ccnc3)c(=O)oc2c1 Show InChI InChI=1S/C20H16N2O3/c1-24-15-7-8-16-18(11-15)25-20(23)17(12-22-10-9-21-13-22)19(16)14-5-3-2-4-6-14/h2-11,13H,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM8935 (5-[(6-methoxy-1-methyl-3,4-dihydronaphthalen-2-yl)...) Show SMILES COc1ccc2C(C)=C(Cc3cnc[nH]3)CCc2c1 |t:7| Show InChI InChI=1S/C16H18N2O/c1-11-12(7-14-9-17-10-18-14)3-4-13-8-15(19-2)5-6-16(11)13/h5-6,8-10H,3-4,7H2,1-2H3,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9918 (4-[(R)-1H-imidazol-1-yl(4-oxo-4H-chromen-3-yl)meth...) Show SMILES O=c1c(coc2ccccc12)[C@@H](c1ccc(cc1)C#N)n1ccnc1 |r| Show InChI InChI=1S/C20H13N3O2/c21-11-14-5-7-15(8-6-14)19(23-10-9-22-13-23)17-12-25-18-4-2-1-3-16(18)20(17)24/h1-10,12-13,19H/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	7.4	30
University of Bologna					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...				J Med Chem 48: 7282-9 (2005) Article DOI: 10.1021/jm058042r BindingDB Entry DOI: 10.7270/Q2JS9NN9
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9477 (6-(1H-Imidazol-1-ylmethyl)-2H-chromen-2-one | CHEM...) Show SMILES O=c1ccc2cc(Cn3ccnc3)ccc2o1 Show InChI InChI=1S/C13H10N2O2/c16-13-4-2-11-7-10(1-3-12(11)17-13)8-15-6-5-14-9-15/h1-7,9H,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	144	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9485 (7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...) Show SMILES O=c1cc(Cn2ccnc2)c2ccc(OCc3ccccc3)cc2o1 Show InChI InChI=1S/C20H16N2O3/c23-20-10-16(12-22-9-8-21-14-22)18-7-6-17(11-19(18)25-20)24-13-15-4-2-1-3-5-15/h1-11,14H,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9476 (5-(1H-Imidazol-1-ylmethyl)-7-methoxy-2H-chromen-2-...) Show SMILES COc1cc(Cn2ccnc2)c2ccc(=O)oc2c1 Show InChI InChI=1S/C14H12N2O3/c1-18-11-6-10(8-16-5-4-15-9-16)12-2-3-14(17)19-13(12)7-11/h2-7,9H,8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	168	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9471 (4-(1H-Imidazol-1-ylmethyl)-7-methoxy-2H-chromen-2-...) Show SMILES COc1ccc2c(Cn3ccnc3)cc(=O)oc2c1 Show InChI InChI=1S/C14H12N2O3/c1-18-11-2-3-12-10(8-16-5-4-15-9-16)6-14(17)19-13(12)7-11/h2-7,9H,8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9917 (3-[(S)-(4-bromophenyl)(1H-imidazol-1-yl)methyl]-4H...) Show SMILES Brc1ccc(cc1)[C@@H](c1coc2ccccc2c1=O)n1ccnc1 |r| Show InChI InChI=1S/C19H13BrN2O2/c20-14-7-5-13(6-8-14)18(22-10-9-21-12-22)16-11-24-17-4-2-1-3-15(17)19(16)23/h1-12,18H/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	7.4	30
University of Bologna					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...				J Med Chem 48: 7282-9 (2005) Article DOI: 10.1021/jm058042r BindingDB Entry DOI: 10.7270/Q2JS9NN9
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50191597 (3-((1H-imidazol-1-yl)methyl)-2-(4-bromophenyl)-4H-...) Show SMILES Brc1ccc(cc1)-c1oc2ccccc2c(=O)c1Cn1ccnc1 Show InChI InChI=1S/C19H13BrN2O2/c20-14-7-5-13(6-8-14)19-16(11-22-10-9-21-12-22)18(23)15-3-1-2-4-17(15)24-19/h1-10,12H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50191597 (3-((1H-imidazol-1-yl)methyl)-2-(4-bromophenyl)-4H-...) Show SMILES Brc1ccc(cc1)-c1oc2ccccc2c(=O)c1Cn1ccnc1 Show InChI InChI=1S/C19H13BrN2O2/c20-14-7-5-13(6-8-14)19-16(11-22-10-9-21-12-22)18(23)15-3-1-2-4-17(15)24-19/h1-10,12H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50191603 (3-((1H-imidazol-1-yl)methyl)-7-methoxy-2-(4-nitrop...) Show SMILES COc1ccc2c(c1)oc(-c1ccc(cc1)[N+]([O-])=O)c(Cn1ccnc1)c2=O Show InChI InChI=1S/C20H15N3O5/c1-27-15-6-7-16-18(10-15)28-20(13-2-4-14(5-3-13)23(25)26)17(19(16)24)11-22-9-8-21-12-22/h2-10,12H,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	468	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50191603 (3-((1H-imidazol-1-yl)methyl)-7-methoxy-2-(4-nitrop...) Show SMILES COc1ccc2c(c1)oc(-c1ccc(cc1)[N+]([O-])=O)c(Cn1ccnc1)c2=O Show InChI InChI=1S/C20H15N3O5/c1-27-15-6-7-16-18(10-15)28-20(13-2-4-14(5-3-13)23(25)26)17(19(16)24)11-22-9-8-21-12-22/h2-10,12H,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	468	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50097372 (3-((1H-imidazol-1-yl)methyl)-7-methoxy-2-phenyl-4H...) Show SMILES COc1ccc2c(c1)oc(-c1ccccc1)c(Cn1ccnc1)c2=O Show InChI InChI=1S/C20H16N2O3/c1-24-15-7-8-16-18(11-15)25-20(14-5-3-2-4-6-14)17(19(16)23)12-22-10-9-21-13-22/h2-11,13H,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50097372 (3-((1H-imidazol-1-yl)methyl)-7-methoxy-2-phenyl-4H...) Show SMILES COc1ccc2c(c1)oc(-c1ccccc1)c(Cn1ccnc1)c2=O Show InChI InChI=1S/C20H16N2O3/c1-24-15-7-8-16-18(11-15)25-20(14-5-3-2-4-6-14)17(19(16)23)12-22-10-9-21-13-22/h2-11,13H,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9919 (4-[(S)-1H-imidazol-1-yl(4-oxo-4H-chromen-3-yl)meth...) Show SMILES O=c1c(coc2ccccc12)[C@H](c1ccc(cc1)C#N)n1ccnc1 |r| Show InChI InChI=1S/C20H13N3O2/c21-11-14-5-7-15(8-6-14)19(23-10-9-22-13-23)17-12-25-18-4-2-1-3-16(18)20(17)24/h1-10,12-13,19H/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	7.4	30
University of Bologna					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...				J Med Chem 48: 7282-9 (2005) Article DOI: 10.1021/jm058042r BindingDB Entry DOI: 10.7270/Q2JS9NN9
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9478 (7-(1H-Imidazol-1-ylmethyl)-2H-chromen-2-one | CHEM...) Show SMILES O=c1ccc2ccc(Cn3ccnc3)cc2o1 Show InChI InChI=1S/C13H10N2O2/c16-13-4-3-11-2-1-10(7-12(11)17-13)8-15-6-5-14-9-15/h1-7,9H,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9473 (4-[2-(1H-Imidazol-1-yl)ethoxy]-2H-chromen-2-one | ...) Show SMILES O=c1cc(OCCn2ccnc2)c2ccccc2o1 Show InChI InChI=1S/C14H12N2O3/c17-14-9-13(11-3-1-2-4-12(11)19-14)18-8-7-16-6-5-15-10-16/h1-6,9-10H,7-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9486 (6-(1H-Imidazol-1-ylmethyl)-2H-chrome-2-thione | 6-...) Show SMILES S=c1ccc2cc(Cn3ccnc3)ccc2o1 Show InChI InChI=1S/C13H10N2OS/c17-13-4-2-11-7-10(1-3-12(11)16-13)8-15-6-5-14-9-15/h1-7,9H,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50191601 (4'-cyano-3-(imidazolylmethyl)-7-methoxyflavone | 4...) Show SMILES COc1ccc2c(c1)oc(-c1ccc(cc1)C#N)c(Cn1ccnc1)c2=O Show InChI InChI=1S/C21H15N3O3/c1-26-16-6-7-17-19(10-16)27-21(15-4-2-14(11-22)3-5-15)18(20(17)25)12-24-9-8-23-13-24/h2-10,13H,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50191601 (4'-cyano-3-(imidazolylmethyl)-7-methoxyflavone | 4...) Show SMILES COc1ccc2c(c1)oc(-c1ccc(cc1)C#N)c(Cn1ccnc1)c2=O Show InChI InChI=1S/C21H15N3O3/c1-26-16-6-7-17-19(10-16)27-21(15-4-2-14(11-22)3-5-15)18(20(17)25)12-24-9-8-23-13-24/h2-10,13H,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9470 (4-(1H-Imidazol-1-ylmethyl)-2H-chromen-2-one | CHEM...) Show SMILES O=c1cc(Cn2ccnc2)c2ccccc2o1 Show InChI InChI=1S/C13H10N2O2/c16-13-7-10(8-15-6-5-14-9-15)11-3-1-2-4-12(11)17-13/h1-7,9H,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9469 (3-(1H-Imidazol-1-ylmethyl)-7-methoxy-2H-chromen-2-...) Show SMILES COc1ccc2cc(Cn3ccnc3)c(=O)oc2c1 Show InChI InChI=1S/C14H12N2O3/c1-18-12-3-2-10-6-11(8-16-5-4-15-9-16)14(17)19-13(10)7-12/h2-7,9H,8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.82E+3	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9462 (1-{2-methyl-5H-indeno[1,2-d]pyrimidin-5-yl}-1H-imi...) Show SMILES Cc1ncc2C(c3ccccc3-c2n1)n1ccnc1 Show InChI InChI=1S/C15H12N4/c1-10-17-8-13-14(18-10)11-4-2-3-5-12(11)15(13)19-7-6-16-9-19/h2-9,15H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9464 (1-(9H-Fluoren-9-yl)-1H-imidazole | CHEMBL225447 | ...) Show SMILES c1cn(cn1)C1c2ccccc2-c2ccccc12 Show InChI InChI=1S/C16H12N2/c1-3-7-14-12(5-1)13-6-2-4-8-15(13)16(14)18-10-9-17-11-18/h1-11,16H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9472 (7-Methoxy-4-(1H-1,2,4-triazol-1-ylmethyl)-2H-chrom...) Show SMILES COc1ccc2c(Cn3cncn3)cc(=O)oc2c1 Show InChI InChI=1S/C13H11N3O3/c1-18-10-2-3-11-9(6-16-8-14-7-15-16)4-13(17)19-12(11)5-10/h2-5,7-8H,6H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9468 (1-(9-Phenyl-9H-fluoren-9-yl)-1H-1,2,4-triazole | C...) Show SMILES c1ncn(n1)C1(c2ccccc2-c2ccccc12)c1ccccc1 Show InChI InChI=1S/C21H15N3/c1-2-8-16(9-3-1)21(24-15-22-14-23-24)19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h1-15H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50191596 (3-((1H-imidazol-1-yl)methyl)-2-(4-bromophenyl)-7-m...) Show SMILES COc1ccc2c(c1)oc(-c1ccc(Br)cc1)c(Cn1ccnc1)c2=O Show InChI InChI=1S/C20H15BrN2O3/c1-25-15-6-7-16-18(10-15)26-20(13-2-4-14(21)5-3-13)17(19(16)24)11-23-9-8-22-12-23/h2-10,12H,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50191596 (3-((1H-imidazol-1-yl)methyl)-2-(4-bromophenyl)-7-m...) Show SMILES COc1ccc2c(c1)oc(-c1ccc(Br)cc1)c(Cn1ccnc1)c2=O Show InChI InChI=1S/C20H15BrN2O3/c1-25-15-6-7-16-18(10-15)26-20(13-2-4-14(21)5-3-13)17(19(16)24)11-23-9-8-22-12-23/h2-10,12H,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of CYP19				J Med Chem 49: 4777-80 (2006) Article DOI: 10.1021/jm060186y BindingDB Entry DOI: 10.7270/Q2668CTW
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9482 (4-(1H-Imidazol-1-ylmethyl)-3-phenyl-2H-chromen-2-o...) Show SMILES O=c1oc2ccccc2c(Cn2ccnc2)c1-c1ccccc1 Show InChI InChI=1S/C19H14N2O2/c22-19-18(14-6-2-1-3-7-14)16(12-21-11-10-20-13-21)15-8-4-5-9-17(15)23-19/h1-11,13H,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.13E+3	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM8935 (5-[(6-methoxy-1-methyl-3,4-dihydronaphthalen-2-yl)...) Show SMILES COc1ccc2C(C)=C(Cc3cnc[nH]3)CCc2c1 |t:7| Show InChI InChI=1S/C16H18N2O/c1-11-12(7-14-9-17-10-18-14)3-4-13-8-15(19-2)5-6-16(11)13/h5-6,8-10H,3-4,7H2,1-2H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9463 (3-(1H-Imidazol-1-ylmethyl)-5H-indeno[1,2-c]pyridaz...) Show SMILES O=C1c2ccccc2-c2nnc(Cn3ccnc3)cc12 Show InChI InChI=1S/C15H10N4O/c20-15-12-4-2-1-3-11(12)14-13(15)7-10(17-18-14)8-19-6-5-16-9-19/h1-7,9H,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.66E+4	n/a	n/a	n/a	n/a	7.4	30
University of Bari					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9463 (3-(1H-Imidazol-1-ylmethyl)-5H-indeno[1,2-c]pyridaz...) Show SMILES O=C1c2ccccc2-c2nnc(Cn3ccnc3)cc12 Show InChI InChI=1S/C15H10N4O/c20-15-12-4-2-1-3-11(12)14-13(15)7-10(17-18-14)8-19-6-5-16-9-19/h1-7,9H,8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9465 (1-(9-Phenyl-9H-fluoren-9-yl)-1H-imidazole | CHEMBL...) Show SMILES c1cn(cn1)C1(c2ccccc2-c2ccccc12)c1ccccc1 Show InChI InChI=1S/C22H16N2/c1-2-8-17(9-3-1)22(24-15-14-23-16-24)20-12-6-4-10-18(20)19-11-5-7-13-21(19)22/h1-16H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9466 (4-(9-Phenyl-9H-fluoren-9-yl)-4H-1,2,4-triazole | F...) Show SMILES c1nncn1C1(c2ccccc2-c2ccccc12)c1ccccc1 Show InChI InChI=1S/C21H15N3/c1-2-8-16(9-3-1)21(24-14-22-23-15-24)19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h1-15H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM9467 (1-(9-Phenyl-9H-fluoren-9-yl)-1H-1,2,3-triazole | F...) Show SMILES c1cn(nn1)C1(c2ccccc2-c2ccccc12)c1ccccc1 Show InChI InChI=1S/C21H15N3/c1-2-8-16(9-3-1)21(24-15-14-22-23-24)19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h1-15H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari					Assay Description The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...				J Med Chem 47: 6792-803 (2004) Article DOI: 10.1021/jm049535j BindingDB Entry DOI: 10.7270/Q2MS3R0C
					More data for this Ligand-Target Pair

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