Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5595 (2-arylamino-pyrimidine deriv. 9e | 4-{[4-amino-6-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5595 (2-arylamino-pyrimidine deriv. 9e | 4-{[4-amino-6-(...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5544 (4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5544 (4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benz...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5594 (2-arylamino-pyrimidine deriv. 9d | 4-{[4-amino-6-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5594 (2-arylamino-pyrimidine deriv. 9d | 4-{[4-amino-6-(...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5593 (2-arylamino-pyrimidine deriv. 9c | 6-(cyclohexylme...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5593 (2-arylamino-pyrimidine deriv. 9c | 6-(cyclohexylme...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5592 (2-arylamino-pyrimidine deriv. 9b | 6-(cyclohexylme...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5592 (2-arylamino-pyrimidine deriv. 9b | 6-(cyclohexylme...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5591 (2-N-(3-bromophenyl)-6-(cyclohexylmethoxy)-5-nitros...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5591 (2-N-(3-bromophenyl)-6-(cyclohexylmethoxy)-5-nitros...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5566 (2,6-Diamino-4-cyclohexylmethoxy-5-nitrosopyrimidin...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5590 (2-arylamino-pyrimidine deriv. 8b | 4-{[4-amino-6-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5566 (2,6-Diamino-4-cyclohexylmethoxy-5-nitrosopyrimidin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5572 (6-(cyclohex-3-en-1-ylmethoxy)-5-nitrosopyrimidine-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5572 (6-(cyclohex-3-en-1-ylmethoxy)-5-nitrosopyrimidine-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5590 (2-arylamino-pyrimidine deriv. 8b | 4-{[4-amino-6-(...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5573 (6-(benzyloxy)-5-nitrosopyrimidine-2,4-diamine | CH...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5573 (6-(benzyloxy)-5-nitrosopyrimidine-2,4-diamine | CH...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5571 ((2S)-2-{[(2,6-diamino-5-nitrosopyrimidin-4-yl)oxy]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.70E+4 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5589 (2-arylamino-pyrimidine deriv. 8a | 4-{[4-amino-6-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.90E+4 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5589 (2-arylamino-pyrimidine deriv. 8a | 4-{[4-amino-6-(...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.30E+4 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 3079-82 (2003) Article DOI: 10.1016/s0960-894x(03)00651-6 BindingDB Entry DOI: 10.7270/Q2R78CDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5571 ((2S)-2-{[(2,6-diamino-5-nitrosopyrimidin-4-yl)oxy]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5586 ([2,4-diamino-6-(cyclohexylmethoxy)pyrimidin-5-yl](...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5587 (5-benzoyl-6-(cyclohexylmethoxy)pyrimidine-2,4-diam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5588 (6-(cyclohexylmethoxy)pyrimidine-2,4,5-triamine | p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5580 (6-(cyclohexylmethoxy)-4-N-(4-methoxyphenyl)-5-nitr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5581 (2,4-diamino-6-(cyclohexylmethoxy)pyrimidine-5-carb...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5582 (6-(cyclohexylmethoxy)-5-[(1E)-(hydroxyimino)methyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5583 (6-(cyclohexylmethoxy)-5-[(1E)-(methoxyimino)methyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5584 (5-[(1E)-[(benzyloxy)imino]methyl]-6-(cyclohexylmet...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5585 ([(E)-{[2,4-diamino-6-(cyclohexylmethoxy)pyrimidin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5586 ([2,4-diamino-6-(cyclohexylmethoxy)pyrimidin-5-yl](...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5587 (5-benzoyl-6-(cyclohexylmethoxy)pyrimidine-2,4-diam...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5588 (6-(cyclohexylmethoxy)pyrimidine-2,4,5-triamine | p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5576 (N-[2-amino-6-(cyclohexylmethoxy)-5-nitrosopyrimidi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5575 (6-(cyclohex-3-en-1-ylmethoxy)pyrimidine-2,4-diamin...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM5574 (6-(cyclohexylmethoxy)pyrimidine-2,4-diamine | NU60...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5579 (6-(cyclohexylmethoxy)-5-nitroso-4-N-phenylpyrimidi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5578 (benzyl N-[2-amino-6-(cyclohexylmethoxy)-5-nitrosop...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5577 (methyl N-[2-amino-6-(cyclohexylmethoxy)-5-nitrosop...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5576 (N-[2-amino-6-(cyclohexylmethoxy)-5-nitrosopyrimidi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5575 (6-(cyclohex-3-en-1-ylmethoxy)pyrimidine-2,4-diamin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5574 (6-(cyclohexylmethoxy)pyrimidine-2,4-diamine | NU60...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5585 ([(E)-{[2,4-diamino-6-(cyclohexylmethoxy)pyrimidin-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5584 (5-[(1E)-[(benzyloxy)imino]methyl]-6-(cyclohexylmet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5583 (6-(cyclohexylmethoxy)-5-[(1E)-(methoxyimino)methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5582 (6-(cyclohexylmethoxy)-5-[(1E)-(hydroxyimino)methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM5581 (2,4-diamino-6-(cyclohexylmethoxy)pyrimidine-5-carb...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle | Assay Description The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ... | Bioorg Med Chem Lett 13: 217-22 (2003) Article DOI: 10.1016/s0960-894x(02)00884-3 BindingDB Entry DOI: 10.7270/Q2W09433 | |||||||||||
More data for this Ligand-Target Pair |
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