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Compile Data Set for Download or QSAR

Found 32 hits with Last Name = 'paul beckett' and Initial = 'r'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arginase-1


(Homo sapiens (Human))
BDBM50427911
PNG
(CHEMBL2326095)
Show SMILES N[C@](CCCCB(O)O)(CCN1CCCC1)C(O)=O |r|
Show InChI InChI=1S/C12H25BN2O4/c14-12(11(16)17,5-1-2-7-13(18)19)6-10-15-8-3-4-9-15/h18-19H,1-10,14H2,(H,16,17)/t12-/m1/s1
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n/an/a 320n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM50427913
PNG
(CHEMBL2326093)
Show SMILES N[C@](CCCCB(O)O)(CCN1CCC(O)CC1)C(O)=O |r|
Show InChI InChI=1S/C13H27BN2O5/c15-13(12(18)19,5-1-2-7-14(20)21)6-10-16-8-3-11(17)4-9-16/h11,17,20-21H,1-10,15H2,(H,18,19)/t13-/m1/s1
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n/an/a 370n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM50427905
PNG
(CHEMBL2326085)
Show SMILES CCN(CC)CC[C@](N)(CCCCB(O)O)C(O)=O |r|
Show InChI InChI=1S/C12H27BN2O4/c1-3-15(4-2)10-8-12(14,11(16)17)7-5-6-9-13(18)19/h18-19H,3-10,14H2,1-2H3,(H,16,17)/t12-/m1/s1
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n/an/a 520n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50427911
PNG
(CHEMBL2326095)
Show SMILES N[C@](CCCCB(O)O)(CCN1CCCC1)C(O)=O |r|
Show InChI InChI=1S/C12H25BN2O4/c14-12(11(16)17,5-1-2-7-13(18)19)6-10-15-8-3-4-9-15/h18-19H,1-10,14H2,(H,16,17)/t12-/m1/s1
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n/an/a 620n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg2 by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM50350311
PNG
(CHEMBL1812661)
Show SMILES [NH3+][C@@H](CCCCB(O)O)C([O-])=O |r|
Show InChI InChI=1S/C6H14BNO4/c8-5(6(9)10)3-1-2-4-7(11)12/h5,11-12H,1-4,8H2,(H,9,10)/t5-/m0/s1
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n/an/a 800n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg1


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50427905
PNG
(CHEMBL2326085)
Show SMILES CCN(CC)CC[C@](N)(CCCCB(O)O)C(O)=O |r|
Show InChI InChI=1S/C12H27BN2O4/c1-3-15(4-2)10-8-12(14,11(16)17)7-5-6-9-13(18)19/h18-19H,3-10,14H2,1-2H3,(H,16,17)/t12-/m1/s1
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n/an/a 934n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg2 by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50427913
PNG
(CHEMBL2326093)
Show SMILES N[C@](CCCCB(O)O)(CCN1CCC(O)CC1)C(O)=O |r|
Show InChI InChI=1S/C13H27BN2O5/c15-13(12(18)19,5-1-2-7-14(20)21)6-10-16-8-3-11(17)4-9-16/h11,17,20-21H,1-10,15H2,(H,18,19)/t13-/m1/s1
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n/an/a 980n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg2 by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50431953
PNG
(CHEMBL2348490)
Show SMILES NCC(N)(CCCCB(O)O)C(O)=O
Show InChI InChI=1S/C7H17BN2O4/c9-5-7(10,6(11)12)3-1-2-4-8(13)14/h13-14H,1-5,9-10H2,(H,11,12)
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n/an/a 1.35E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg2 by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM50350311
PNG
(CHEMBL1812661)
Show SMILES [NH3+][C@@H](CCCCB(O)O)C([O-])=O |r|
Show InChI InChI=1S/C6H14BNO4/c8-5(6(9)10)3-1-2-4-7(11)12/h5,11-12H,1-4,8H2,(H,9,10)/t5-/m0/s1
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n/an/a 1.45E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50350311
PNG
(CHEMBL1812661)
Show SMILES [NH3+][C@@H](CCCCB(O)O)C([O-])=O |r|
Show InChI InChI=1S/C6H14BNO4/c8-5(6(9)10)3-1-2-4-7(11)12/h5,11-12H,1-4,8H2,(H,9,10)/t5-/m0/s1
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n/an/a 1.92E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg2 by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM50431953
PNG
(CHEMBL2348490)
Show SMILES NCC(N)(CCCCB(O)O)C(O)=O
Show InChI InChI=1S/C7H17BN2O4/c9-5-7(10,6(11)12)3-1-2-4-8(13)14/h13-14H,1-5,9-10H2,(H,11,12)
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n/an/a 2.07E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM50431958
PNG
(CHEMBL2348496)
Show SMILES NC(CO)(CCCCB(O)O)C(O)=O
Show InChI InChI=1S/C7H16BNO5/c9-7(5-10,6(11)12)3-1-2-4-8(13)14/h10,13-14H,1-5,9H2,(H,11,12)
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n/an/a 2.25E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM50431954
PNG
(CHEMBL2348492)
Show SMILES NC(CCCCB(O)O)(Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C10H18BN3O4/c12-10(9(15)16,3-1-2-4-11(17)18)5-8-6-13-7-14-8/h6-7,17-18H,1-5,12H2,(H,13,14)(H,15,16)
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n/an/a 2.28E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM50431952
PNG
(CHEMBL2348491)
Show SMILES NC(CCCCB(O)O)(CNCc1ccccc1)C(O)=O
Show InChI InChI=1S/C14H23BN2O4/c16-14(13(18)19,8-4-5-9-15(20)21)11-17-10-12-6-2-1-3-7-12/h1-3,6-7,17,20-21H,4-5,8-11,16H2,(H,18,19)
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n/an/a 3.26E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM50350309
PNG
(CHEMBL1812662)
Show SMILES CC([NH3+])(CCCCB(O)O)C([O-])=O
Show InChI InChI=1S/C7H16BNO4/c1-7(9,6(10)11)4-2-3-5-8(12)13/h12-13H,2-5,9H2,1H3,(H,10,11)
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n/an/a 3.43E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50431954
PNG
(CHEMBL2348492)
Show SMILES NC(CCCCB(O)O)(Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C10H18BN3O4/c12-10(9(15)16,3-1-2-4-11(17)18)5-8-6-13-7-14-8/h6-7,17-18H,1-5,12H2,(H,13,14)(H,15,16)
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n/an/a 3.72E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg2 by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50431951
PNG
(CHEMBL2348489)
Show SMILES NC(CCCCB(O)O)(CCN1CCOCC1)C(O)=O
Show InChI InChI=1S/C12H25BN2O5/c14-12(11(16)17,3-1-2-5-13(18)19)4-6-15-7-9-20-10-8-15/h18-19H,1-10,14H2,(H,16,17)
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n/an/a 4.02E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg2 by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM50431961
PNG
(CHEMBL2348498)
Show SMILES CCC(N)(CCCCB(O)O)C(O)=O
Show InChI InChI=1S/C8H18BNO4/c1-2-8(10,7(11)12)5-3-4-6-9(13)14/h13-14H,2-6,10H2,1H3,(H,11,12)
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n/an/a 4.10E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50431958
PNG
(CHEMBL2348496)
Show SMILES NC(CO)(CCCCB(O)O)C(O)=O
Show InChI InChI=1S/C7H16BNO5/c9-7(5-10,6(11)12)3-1-2-4-8(13)14/h10,13-14H,1-5,9H2,(H,11,12)
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n/an/a 4.28E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg2 by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50431956
PNG
(CHEMBL2348495)
Show SMILES NC(CCCO)(CCCCB(O)O)C(O)=O
Show InChI InChI=1S/C9H20BNO5/c11-9(8(13)14,5-3-7-12)4-1-2-6-10(15)16/h12,15-16H,1-7,11H2,(H,13,14)
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n/an/a 4.50E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg2 by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50431961
PNG
(CHEMBL2348498)
Show SMILES CCC(N)(CCCCB(O)O)C(O)=O
Show InChI InChI=1S/C8H18BNO4/c1-2-8(10,7(11)12)5-3-4-6-9(13)14/h13-14H,2-6,10H2,1H3,(H,11,12)
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n/an/a 4.60E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg2 by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50350309
PNG
(CHEMBL1812662)
Show SMILES CC([NH3+])(CCCCB(O)O)C([O-])=O
Show InChI InChI=1S/C7H16BNO4/c1-7(9,6(10)11)4-2-3-5-8(12)13/h12-13H,2-5,9H2,1H3,(H,10,11)
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n/an/a 5.07E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg2 by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM50431955
PNG
(CHEMBL2348493)
Show SMILES COCCCC(N)(CCCCB(O)O)C(O)=O
Show InChI InChI=1S/C10H22BNO5/c1-17-8-4-6-10(12,9(13)14)5-2-3-7-11(15)16/h15-16H,2-8,12H2,1H3,(H,13,14)
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n/an/a 5.12E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM50431951
PNG
(CHEMBL2348489)
Show SMILES NC(CCCCB(O)O)(CCN1CCOCC1)C(O)=O
Show InChI InChI=1S/C12H25BN2O5/c14-12(11(16)17,3-1-2-5-13(18)19)4-6-15-7-9-20-10-8-15/h18-19H,1-10,14H2,(H,16,17)
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n/an/a 5.38E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50431952
PNG
(CHEMBL2348491)
Show SMILES NC(CCCCB(O)O)(CNCc1ccccc1)C(O)=O
Show InChI InChI=1S/C14H23BN2O4/c16-14(13(18)19,8-4-5-9-15(20)21)11-17-10-12-6-2-1-3-7-12/h1-3,6-7,17,20-21H,4-5,8-11,16H2,(H,18,19)
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n/an/a 5.98E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg2 by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50431955
PNG
(CHEMBL2348493)
Show SMILES COCCCC(N)(CCCCB(O)O)C(O)=O
Show InChI InChI=1S/C10H22BNO5/c1-17-8-4-6-10(12,9(13)14)5-2-3-7-11(15)16/h15-16H,2-8,12H2,1H3,(H,13,14)
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n/an/a 6.44E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg2 by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM50431959
PNG
(CHEMBL2348497)
Show SMILES NC(CCCCB(O)O)(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C13H20BNO4/c15-13(12(16)17,8-4-5-9-14(18)19)10-11-6-2-1-3-7-11/h1-3,6-7,18-19H,4-5,8-10,15H2,(H,16,17)
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n/an/a 1.05E+4n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM50431960
PNG
(CHEMBL2348499)
Show SMILES CC(C)C(N)(CCCCB(O)O)C(O)=O
Show InChI InChI=1S/C9H20BNO4/c1-7(2)9(11,8(12)13)5-3-4-6-10(14)15/h7,14-15H,3-6,11H2,1-2H3,(H,12,13)
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n/an/a 1.12E+4n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50431960
PNG
(CHEMBL2348499)
Show SMILES CC(C)C(N)(CCCCB(O)O)C(O)=O
Show InChI InChI=1S/C9H20BNO4/c1-7(2)9(11,8(12)13)5-3-4-6-10(14)15/h7,14-15H,3-6,11H2,1-2H3,(H,12,13)
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n/an/a 1.55E+4n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg2 by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50431959
PNG
(CHEMBL2348497)
Show SMILES NC(CCCCB(O)O)(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C13H20BNO4/c15-13(12(16)17,8-4-5-9-14(18)19)10-11-6-2-1-3-7-11/h1-3,6-7,18-19H,4-5,8-10,15H2,(H,16,17)
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n/an/a 1.70E+4n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg2 by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM50431957
PNG
(CHEMBL2348494)
Show SMILES NC(CCO)(CCCCB(O)O)C(O)=O
Show InChI InChI=1S/C8H18BNO5/c10-8(4-6-11,7(12)13)3-1-2-5-9(14)15/h11,14-15H,1-6,10H2,(H,12,13)
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n/an/a 1.90E+4n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50431957
PNG
(CHEMBL2348494)
Show SMILES NC(CCO)(CCCCB(O)O)C(O)=O
Show InChI InChI=1S/C8H18BNO5/c10-8(4-6-11,7(12)13)3-1-2-5-9(14)15/h11,14-15H,1-6,10H2,(H,12,13)
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n/an/a 5.70E+4n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery

Curated by ChEMBL


Assay Description
Inhibition of human Arg2 by colorimetric assay


Bioorg Med Chem Lett 23: 2027-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.024
BindingDB Entry DOI: 10.7270/Q22J6D8K
More data for this
Ligand-Target Pair