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Compile Data Set for Download or QSAR

Found 64 hits with Last Name = 'pavlova' and Initial = 'oa'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474596
PNG
(CHEMBL79332)
Show SMILES Fc1cc(\C=C\c2cc(OC[C@@H]3CCN3)cnc2Cl)ccn1
Show InChI InChI=1S/C16H15ClFN3O/c17-16-12(2-1-11-3-5-20-15(18)7-11)8-14(9-21-16)22-10-13-4-6-19-13/h1-3,5,7-9,13,19H,4,6,10H2/b2-1+/t13-/m0/s1
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 0.00310n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474584
PNG
(CHEMBL79387)
Show SMILES Clc1ncc(OC[C@@H]2CCN2)cc1-c1ccnc(Br)c1
Show InChI InChI=1S/C14H13BrClN3O/c15-13-5-9(1-3-18-13)12-6-11(7-19-14(12)16)20-8-10-2-4-17-10/h1,3,5-7,10,17H,2,4,8H2/t10-/m0/s1
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 0.00330n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474594
PNG
(CHEMBL86050)
Show SMILES Fc1ncc(cc1Br)-c1cc(OC[C@@H]2CCN2)cnc1Cl
Show InChI InChI=1S/C14H12BrClFN3O/c15-12-3-8(5-20-14(12)17)11-4-10(6-19-13(11)16)21-7-9-1-2-18-9/h3-6,9,18H,1-2,7H2/t9-/m0/s1
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 0.00400n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474583
PNG
(CHEMBL86051)
Show SMILES Clc1ncc(OC[C@@H]2CCN2)cc1-c1ccc(Br)nc1
Show InChI InChI=1S/C14H13BrClN3O/c15-13-2-1-9(6-18-13)12-5-11(7-19-14(12)16)20-8-10-3-4-17-10/h1-2,5-7,10,17H,3-4,8H2/t10-/m0/s1
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 0.00430n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474587
PNG
(CHEMBL314718)
Show SMILES Clc1ccc(cn1)-c1cc(OC[C@@H]2CCN2)cnc1Cl
Show InChI InChI=1S/C14H13Cl2N3O/c15-13-2-1-9(6-18-13)12-5-11(7-19-14(12)16)20-8-10-3-4-17-10/h1-2,5-7,10,17H,3-4,8H2/t10-/m0/s1
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 0.00450n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474595
PNG
(CHEMBL79594)
Show SMILES Fc1cc(ccn1)-c1cc(OC[C@@H]2CCN2)cnc1Cl |r|
Show InChI InChI=1S/C14H13ClFN3O/c15-14-12(9-1-3-18-13(16)5-9)6-11(7-19-14)20-8-10-2-4-17-10/h1,3,5-7,10,17H,2,4,8H2/t10-/m0/s1
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 0.00480n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474582
PNG
(CHEMBL83444)
Show SMILES Fc1ccc(cn1)-c1cc(OC[C@@H]2CCN2)cnc1Cl
Show InChI InChI=1S/C14H13ClFN3O/c15-14-12(9-1-2-13(16)18-6-9)5-11(7-19-14)20-8-10-3-4-17-10/h1-2,5-7,10,17H,3-4,8H2/t10-/m0/s1
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 0.00490n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474593
PNG
(CHEMBL313877)
Show SMILES Clc1ncc(OC[C@@H]2CCN2)cc1\C=C\c1ccnc(Br)c1
Show InChI InChI=1S/C16H15BrClN3O/c17-15-7-11(3-5-20-15)1-2-12-8-14(9-21-16(12)18)22-10-13-4-6-19-13/h1-3,5,7-9,13,19H,4,6,10H2/b2-1+/t13-/m0/s1
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 0.00520n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474591
PNG
(CHEMBL79515)
Show SMILES Clc1ncc(OC[C@@H]2CCCN2)cc1\C=C\c1ccnc(Br)c1
Show InChI InChI=1S/C17H17BrClN3O/c18-16-8-12(5-7-21-16)3-4-13-9-15(10-22-17(13)19)23-11-14-2-1-6-20-14/h3-5,7-10,14,20H,1-2,6,11H2/b4-3+/t14-/m0/s1
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 0.00560n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474598
PNG
(CHEMBL79702)
Show SMILES Brc1ncc(OC[C@@H]2CCN2)cc1-c1cccnc1
Show InChI InChI=1S/C14H14BrN3O/c15-14-13(10-2-1-4-16-7-10)6-12(8-18-14)19-9-11-3-5-17-11/h1-2,4,6-8,11,17H,3,5,9H2/t11-/m0/s1
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 0.00660n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474592
PNG
(CHEMBL83738)
Show SMILES Fc1ncc(\C=C\c2cc(OC[C@@H]3CCN3)cnc2Cl)cc1Br
Show InChI InChI=1S/C16H14BrClFN3O/c17-14-5-10(7-22-16(14)19)1-2-11-6-13(8-21-15(11)18)23-9-12-3-4-20-12/h1-2,5-8,12,20H,3-4,9H2/b2-1+/t12-/m0/s1
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 0.00770n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474585
PNG
(CHEMBL312132)
Show SMILES Clc1ncc(OC[C@@H]2CCN2)cc1-c1cccnc1
Show InChI InChI=1S/C14H14ClN3O/c15-14-13(10-2-1-4-16-7-10)6-12(8-18-14)19-9-11-3-5-17-11/h1-2,4,6-8,11,17H,3,5,9H2/t11-/m0/s1
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 0.00810n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474590
PNG
(CHEMBL309292)
Show SMILES Fc1ccnc[n+]1-c1cc(OC[C@@H]2CCN2)cnc1Cl
Show InChI InChI=1S/C13H13ClFN4O/c14-13-11(19-8-16-3-2-12(19)15)5-10(6-18-13)20-7-9-1-4-17-9/h2-3,5-6,8-9,17H,1,4,7H2/q+1/t9-/m0/s1
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 0.00880n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50049757
PNG
(()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...)
Show SMILES Clc1ccc(cn1)C1CC2CCC1N2 |TLB:4:7:11.10:13|
Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2
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 0.00900n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50114773
PNG
(5-(Azetidin-2-ylmethoxy)-2-chloro-3-(2-pyridin-4-y...)
Show SMILES Clc1ncc(OCC2CCN2)cc1\C=C\c1ccncc1
Show InChI InChI=1S/C16H16ClN3O/c17-16-13(2-1-12-3-6-18-7-4-12)9-15(10-20-16)21-11-14-5-8-19-14/h1-4,6-7,9-10,14,19H,5,8,11H2/b2-1+
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 0.00900n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Binding affinity for nAChR with [3H]-imidacloprid in Drosophila

J Med Chem 45: 2841-9 (2002)


BindingDB Entry DOI: 10.7270/Q2FN15JT
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474586
PNG
(CHEMBL80040)
Show SMILES Clc1ncc(OC[C@@H]2CCN2)cc1\C=C\c1ccncc1
Show InChI InChI=1S/C16H16ClN3O/c17-16-13(2-1-12-3-6-18-7-4-12)9-15(10-20-16)21-11-14-5-8-19-14/h1-4,6-7,9-10,14,19H,5,8,11H2/b2-1+/t14-/m0/s1
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 0.00900n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474588
PNG
(CHEMBL310197)
Show SMILES Fc1cc(\C=C\c2cc(OC[C@@H]3CCCN3)cnc2Cl)ccn1
Show InChI InChI=1S/C17H17ClFN3O/c18-17-13(4-3-12-5-7-21-16(19)8-12)9-15(10-22-17)23-11-14-2-1-6-20-14/h3-5,7-10,14,20H,1-2,6,11H2/b4-3+/t14-/m0/s1
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 0.00940n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50049757
PNG
(()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...)
Show SMILES Clc1ccc(cn1)C1CC2CCC1N2 |TLB:4:7:11.10:13|
Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2
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 0.0100n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Binding affinity for nAChR with [3H]-imidacloprid in Myzus persicae

J Med Chem 45: 2841-9 (2002)


BindingDB Entry DOI: 10.7270/Q2FN15JT
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50114771
PNG
(2-Chloro-3-(2-pyridin-4-yl-ethyl)-5-(pyrrolidin-2-...)
Show SMILES Clc1ncc(OCC2CCCN2)cc1CCc1ccncc1
Show InChI InChI=1S/C17H20ClN3O/c18-17-14(4-3-13-5-8-19-9-6-13)10-16(11-21-17)22-12-15-2-1-7-20-15/h5-6,8-11,15,20H,1-4,7,12H2
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 0.0110n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes

J Med Chem 45: 2841-9 (2002)


BindingDB Entry DOI: 10.7270/Q2FN15JT
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474597
PNG
(CHEMBL83608)
Show SMILES Ic1ncc(OC[C@@H]2CCN2)cc1-c1cccnc1
Show InChI InChI=1S/C14H14IN3O/c15-14-13(10-2-1-4-16-7-10)6-12(8-18-14)19-9-11-3-5-17-11/h1-2,4,6-8,11,17H,3,5,9H2/t11-/m0/s1
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 0.0120n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50114774
PNG
(2-Chloro-3-(2-pyridin-4-yl-vinyl)-5-(pyrrolidin-2-...)
Show SMILES Clc1ncc(OCC2CCCN2)cc1\C=C\c1ccncc1
Show InChI InChI=1S/C17H18ClN3O/c18-17-14(4-3-13-5-8-19-9-6-13)10-16(11-21-17)22-12-15-2-1-7-20-15/h3-6,8-11,15,20H,1-2,7,12H2/b4-3+
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 0.0150n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Binding affinity for nAChR with [3H]-imidacloprid in Drosophila

J Med Chem 45: 2841-9 (2002)


BindingDB Entry DOI: 10.7270/Q2FN15JT
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474581
PNG
(CHEMBL83986)
Show SMILES Fc1ccc(cn1)-c1cc(OC[C@@H]2CCCN2)cnc1Cl
Show InChI InChI=1S/C15H15ClFN3O/c16-15-13(10-3-4-14(17)19-7-10)6-12(8-20-15)21-9-11-2-1-5-18-11/h3-4,6-8,11,18H,1-2,5,9H2/t11-/m0/s1
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 0.0180n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474580
PNG
(CHEMBL84154)
Show SMILES Clc1ncc(OC[C@@H]2CCCN2)cc1-c1ccc(Br)nc1
Show InChI InChI=1S/C15H15BrClN3O/c16-14-4-3-10(7-19-14)13-6-12(8-20-15(13)17)21-9-11-2-1-5-18-11/h3-4,6-8,11,18H,1-2,5,9H2/t11-/m0/s1
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 0.0200n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474599
PNG
(CHEMBL79737)
Show SMILES Clc1ncc(OC[C@@H]2CCCN2)cc1-c1cccnc1
Show InChI InChI=1S/C15H16ClN3O/c16-15-14(11-3-1-5-17-8-11)7-13(9-19-15)20-10-12-4-2-6-18-12/h1,3,5,7-9,12,18H,2,4,6,10H2/t12-/m0/s1
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 0.0210n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50114768
PNG
(2-Chloro-5-(1-methyl-pyrrolidin-2-ylmethoxy)-3-(2-...)
Show SMILES CN1CCCC1COc1cnc(Cl)c(CCc2ccncc2)c1
Show InChI InChI=1S/C18H22ClN3O/c1-22-10-2-3-16(22)13-23-17-11-15(18(19)21-12-17)5-4-14-6-8-20-9-7-14/h6-9,11-12,16H,2-5,10,13H2,1H3
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 0.0230n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes

J Med Chem 45: 2841-9 (2002)


BindingDB Entry DOI: 10.7270/Q2FN15JT
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50114767
PNG
(2-Chloro-3-(2-pyridin-3-yl-vinyl)-5-(pyrrolidin-2-...)
Show SMILES Clc1ncc(OCC2CCCN2)cc1\C=C\c1cccnc1
Show InChI InChI=1S/C17H18ClN3O/c18-17-14(6-5-13-3-1-7-19-10-13)9-16(11-21-17)22-12-15-4-2-8-20-15/h1,3,5-7,9-11,15,20H,2,4,8,12H2/b6-5+
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 0.0280n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Binding affinity for nAChR with [3H]-imidacloprid in Drosophila

J Med Chem 45: 2841-9 (2002)


BindingDB Entry DOI: 10.7270/Q2FN15JT
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50114769
PNG
(2-Chloro-5-(1-methyl-pyrrolidin-2-ylmethoxy)-3-(2-...)
Show SMILES CN1CCCC1COc1cnc(Cl)c(\C=C\c2ccncc2)c1
Show InChI InChI=1S/C18H20ClN3O/c1-22-10-2-3-16(22)13-23-17-11-15(18(19)21-12-17)5-4-14-6-8-20-9-7-14/h4-9,11-12,16H,2-3,10,13H2,1H3/b5-4+
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 0.0280n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Binding affinity for nAChR with [3H]-imidacloprid in Myzus persicae

J Med Chem 45: 2841-9 (2002)


BindingDB Entry DOI: 10.7270/Q2FN15JT
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50062639
PNG
(5-((S)-1-Azetidin-2-ylmethoxy)-2-chloro-pyridine |...)
Show SMILES Clc1ccc(OC[C@@H]2CCN2)cn1
Show InChI InChI=1S/C9H11ClN2O/c10-9-2-1-8(5-12-9)13-6-7-3-4-11-7/h1-2,5,7,11H,3-4,6H2/t7-/m0/s1
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 0.0340n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50066788
PNG
((S)-3-(azetidin-2-ylmethoxy)-2-fluoropyridine | 3-...)
Show SMILES Fc1ncccc1OC[C@@H]1CCN1
Show InChI InChI=1S/C9H11FN2O/c10-9-8(2-1-4-12-9)13-6-7-3-5-11-7/h1-2,4,7,11H,3,5-6H2/t7-/m0/s1
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 0.0610n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474589
PNG
(CHEMBL79854)
Show SMILES Fc1ncc(OC[C@@H]2CCN2)cc1-c1cccnc1
Show InChI InChI=1S/C14H14FN3O/c15-14-13(10-2-1-4-16-7-10)6-12(8-18-14)19-9-11-3-5-17-11/h1-2,4,6-8,11,17H,3,5,9H2/t11-/m0/s1
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 0.0660n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50114775
PNG
(2-Chloro-5-(1-methyl-azetidin-2-ylmethoxy)-3-(2-py...)
Show SMILES CN1CCC1COc1cnc(Cl)c(\C=C\c2ccncc2)c1
Show InChI InChI=1S/C17H18ClN3O/c1-21-9-6-15(21)12-22-16-10-14(17(18)20-11-16)3-2-13-4-7-19-8-5-13/h2-5,7-8,10-11,15H,6,9,12H2,1H3/b3-2+
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 0.0720n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes

J Med Chem 45: 2841-9 (2002)


BindingDB Entry DOI: 10.7270/Q2FN15JT
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50114778
PNG
(2-Chloro-5-(1-methyl-pyrrolidin-2-ylmethoxy)-3-(2-...)
Show SMILES CN1CCCC1COc1cnc(Cl)c(\C=C\c2cccnc2)c1
Show InChI InChI=1S/C18H20ClN3O/c1-22-9-3-5-16(22)13-23-17-10-15(18(19)21-12-17)7-6-14-4-2-8-20-11-14/h2,4,6-8,10-12,16H,3,5,9,13H2,1H3/b7-6+
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 0.0880n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Binding affinity for nAChR with [3H]-imidacloprid in Myzus persicae

J Med Chem 45: 2841-9 (2002)


BindingDB Entry DOI: 10.7270/Q2FN15JT
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50114776
PNG
(2-Chloro-5-(1-methyl-pyrrolidin-2-ylmethoxy)-3-(2-...)
Show SMILES CN1CCCC1COc1cnc(Cl)c(\C=C\c2ccccn2)c1
Show InChI InChI=1S/C18H20ClN3O/c1-22-10-4-6-16(22)13-23-17-11-14(18(19)21-12-17)7-8-15-5-2-3-9-20-15/h2-3,5,7-9,11-12,16H,4,6,10,13H2,1H3/b8-7+
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 0.265n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Binding affinity for nAChR with [3H]-imidacloprid in Myzus persicae

J Med Chem 45: 2841-9 (2002)


BindingDB Entry DOI: 10.7270/Q2FN15JT
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50114777
PNG
(2-Chloro-3-(2-pyridin-2-yl-vinyl)-5-(pyrrolidin-2-...)
Show SMILES Clc1ncc(OCC2CCCN2)cc1\C=C\c1ccccn1
Show InChI InChI=1S/C17H18ClN3O/c18-17-13(6-7-14-4-1-2-8-19-14)10-16(11-21-17)22-12-15-5-3-9-20-15/h1-2,4,6-8,10-11,15,20H,3,5,9,12H2/b7-6+
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 0.331n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Binding affinity for nAChR with [3H]-imidacloprid in Drosophila

J Med Chem 45: 2841-9 (2002)


BindingDB Entry DOI: 10.7270/Q2FN15JT
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM21279
PNG
(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)
Show SMILES Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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 0.600n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Binding affinity was determined by using a competition assay with [125 I]- AM251 against rat cannabinoid receptor 1

J Med Chem 46: 642-5 (2003)


Article DOI: 10.1021/jm020157x
BindingDB Entry DOI: 10.7270/Q27M079X
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50172556
PNG
((4-Fluoro-naphthalen-1-yl)-[1-(1-methyl-piperidin-...)
Show SMILES CN1CCCCC1Cn1cc(C(=O)c2ccc(F)c3ccccc23)c2ccccc12
Show InChI InChI=1S/C26H25FN2O/c1-28-15-7-6-8-18(28)16-29-17-23(21-11-4-5-12-25(21)29)26(30)22-13-14-24(27)20-10-3-2-9-19(20)22/h2-5,9-14,17-18H,6-8,15-16H2,1H3
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 0.700n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
In vitro binding affinity aganist rat cannabinoid receptor 1 using 0.5 nM [3H]-CP- 55940

J Med Chem 48: 5813-22 (2005)


Article DOI: 10.1021/jm0502743
BindingDB Entry DOI: 10.7270/Q23X865M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50172553
PNG
(CHEMBL68641 | [1-(1-Methyl-piperidin-2-ylmethyl)-1...)
Show SMILES CN1CCCCC1Cn1cc(C(=O)c2cccc3ccccc23)c2ccccc12
Show InChI InChI=1S/C26H26N2O/c1-27-16-7-6-11-20(27)17-28-18-24(22-13-4-5-15-25(22)28)26(29)23-14-8-10-19-9-2-3-12-21(19)23/h2-5,8-10,12-15,18,20H,6-7,11,16-17H2,1H3
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 0.900n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
In vitro binding affinity aganist rat cannabinoid receptor 1 using 0.5 nM [3H]-CP- 55940

J Med Chem 48: 5813-22 (2005)


Article DOI: 10.1021/jm0502743
BindingDB Entry DOI: 10.7270/Q23X865M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50172549
PNG
((4-Methyl-naphthalen-1-yl)-[1-(1-methyl-piperidin-...)
Show SMILES CN1CCCCC1Cn1cc(C(=O)c2ccc(C)c3ccccc23)c2ccccc12
Show InChI InChI=1S/C27H28N2O/c1-19-14-15-24(22-11-4-3-10-21(19)22)27(30)25-18-29(26-13-6-5-12-23(25)26)17-20-9-7-8-16-28(20)2/h3-6,10-15,18,20H,7-9,16-17H2,1-2H3
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 1.10n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
In vitro binding affinity aganist rat cannabinoid receptor 1 using 0.5 nM [3H]-CP- 55940

J Med Chem 48: 5813-22 (2005)


Article DOI: 10.1021/jm0502743
BindingDB Entry DOI: 10.7270/Q23X865M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50172543
PNG
(4-[1-(1-Methyl-piperidin-2-ylmethyl)-1H-indole-3-c...)
Show SMILES CN1CCCCC1Cn1cc(C(=O)c2ccc(C#N)c3ccccc23)c2ccccc12
Show InChI InChI=1S/C27H25N3O/c1-29-15-7-6-8-20(29)17-30-18-25(23-11-4-5-12-26(23)30)27(31)24-14-13-19(16-28)21-9-2-3-10-22(21)24/h2-5,9-14,18,20H,6-8,15,17H2,1H3
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 1.10n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
In vitro binding affinity aganist rat cannabinoid receptor 1 using 0.5 nM [3H]-CP- 55940

J Med Chem 48: 5813-22 (2005)


Article DOI: 10.1021/jm0502743
BindingDB Entry DOI: 10.7270/Q23X865M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50172545
PNG
((2-Iodo-phenyl)-[1-((S)-1-methyl-piperidin-2-ylmet...)
Show SMILES CN1CCCCC1Cn1cc(C(=O)c2ccccc2I)c2ccccc12
Show InChI InChI=1S/C22H23IN2O/c1-24-13-7-6-8-16(24)14-25-15-19(17-9-3-5-12-21(17)25)22(26)18-10-2-4-11-20(18)23/h2-5,9-12,15-16H,6-8,13-14H2,1H3
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 1.20n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
In vitro binding affinity aganist rat cannabinoid receptor 1 using 0.5 nM [3H]-CP- 55940

J Med Chem 48: 5813-22 (2005)


Article DOI: 10.1021/jm0502743
BindingDB Entry DOI: 10.7270/Q23X865M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50172555
PNG
(CHEMBL364223 | [4-(2-Hydroxy-ethyl)-naphthalen-1-y...)
Show SMILES CN1CCCCC1Cn1cc(C(=O)c2ccc(CCO)c3ccccc23)c2ccccc12
Show InChI InChI=1S/C28H30N2O2/c1-29-16-7-6-8-21(29)18-30-19-26(24-11-4-5-12-27(24)30)28(32)25-14-13-20(15-17-31)22-9-2-3-10-23(22)25/h2-5,9-14,19,21,31H,6-8,15-18H2,1H3
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 1.30n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
In vitro binding affinity aganist rat cannabinoid receptor 1 using 0.5 nM [3H]-CP- 55940

J Med Chem 48: 5813-22 (2005)


Article DOI: 10.1021/jm0502743
BindingDB Entry DOI: 10.7270/Q23X865M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50172546
PNG
(CHEMBL194313 | [1-(1-Methyl-piperidin-2-ylmethyl)-...)
Show SMILES CN1CCCCC1Cn1nc(C(=O)c2cccc3ccccc23)c2ccccc12
Show InChI InChI=1S/C25H25N3O/c1-27-16-7-6-11-19(27)17-28-23-15-5-4-13-22(23)24(26-28)25(29)21-14-8-10-18-9-2-3-12-20(18)21/h2-5,8-10,12-15,19H,6-7,11,16-17H2,1H3
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 1.40n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
In vitro binding affinity aganist rat cannabinoid receptor 1 using 0.5 nM [3H]-CP- 55940

J Med Chem 48: 5813-22 (2005)


Article DOI: 10.1021/jm0502743
BindingDB Entry DOI: 10.7270/Q23X865M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50123685
PNG
(4-Bromo-5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl...)
Show SMILES Clc1ccc(cc1)-c1c(Br)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C21H18BrCl3N4O/c22-18-19(21(30)27-28-10-2-1-3-11-28)26-29(17-9-8-15(24)12-16(17)25)20(18)13-4-6-14(23)7-5-13/h4-9,12H,1-3,10-11H2,(H,27,30)
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 1.40n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Binding affinity was determined by using a competition assay with [125 I]- AM251 against rat cannabinoid receptor 1

J Med Chem 46: 642-5 (2003)


Article DOI: 10.1021/jm020157x
BindingDB Entry DOI: 10.7270/Q27M079X
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50172551
PNG
((4-Bromo-naphthalen-1-yl)-[1-(1-methyl-piperidin-2...)
Show SMILES CN1CCCCC1Cn1cc(C(=O)c2ccc(Br)c3ccccc23)c2ccccc12
Show InChI InChI=1S/C26H25BrN2O/c1-28-15-7-6-8-18(28)16-29-17-23(21-11-4-5-12-25(21)29)26(30)22-13-14-24(27)20-10-3-2-9-19(20)22/h2-5,9-14,17-18H,6-8,15-16H2,1H3
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 1.70n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
In vitro binding affinity aganist rat cannabinoid receptor 1 using 0.5 nM [3H]-CP- 55940

J Med Chem 48: 5813-22 (2005)


Article DOI: 10.1021/jm0502743
BindingDB Entry DOI: 10.7270/Q23X865M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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 1.80n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Binding affinity was determined by using a competition assay with [125 I]- AM251 against rat cannabinoid receptor 1

J Med Chem 46: 642-5 (2003)


Article DOI: 10.1021/jm020157x
BindingDB Entry DOI: 10.7270/Q27M079X
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50172547
PNG
((4-Hydroxy-naphthalen-1-yl)-[1-(1-methyl-piperidin...)
Show SMILES CN1CCCCC1Cn1cc(C(=O)c2ccc(O)c3ccccc23)c2ccccc12
Show InChI InChI=1S/C26H26N2O2/c1-27-15-7-6-8-18(27)16-28-17-23(20-10-4-5-12-24(20)28)26(30)22-13-14-25(29)21-11-3-2-9-19(21)22/h2-5,9-14,17-18,29H,6-8,15-16H2,1H3
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 2.20n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
In vitro binding affinity aganist rat cannabinoid receptor 1 using 0.5 nM [3H]-CP- 55940

J Med Chem 48: 5813-22 (2005)


Article DOI: 10.1021/jm0502743
BindingDB Entry DOI: 10.7270/Q23X865M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50172548
PNG
((4-Methoxy-naphthalen-1-yl)-[1-(1-methyl-piperidin...)
Show SMILES COc1ccc(C(=O)c2cn(CC3CCCCN3C)c3ccccc23)c2ccccc12
Show InChI InChI=1S/C27H28N2O2/c1-28-16-8-7-9-19(28)17-29-18-24(21-11-5-6-13-25(21)29)27(30)23-14-15-26(31-2)22-12-4-3-10-20(22)23/h3-6,10-15,18-19H,7-9,16-17H2,1-2H3
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 2.30n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
In vitro binding affinity aganist rat cannabinoid receptor 1 using 0.5 nM [3H]-CP- 55940

J Med Chem 48: 5813-22 (2005)


Article DOI: 10.1021/jm0502743
BindingDB Entry DOI: 10.7270/Q23X865M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50172544
PNG
((6-Hydroxy-naphthalen-1-yl)-[1-(1-methyl-piperidin...)
Show SMILES CN1CCCCC1Cn1cc(C(=O)c2cccc3cc(O)ccc23)c2ccccc12
Show InChI InChI=1S/C26H26N2O2/c1-27-14-5-4-8-19(27)16-28-17-24(22-9-2-3-11-25(22)28)26(30)23-10-6-7-18-15-20(29)12-13-21(18)23/h2-3,6-7,9-13,15,17,19,29H,4-5,8,14,16H2,1H3
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 4n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
In vitro binding affinity aganist rat cannabinoid receptor 1 using 0.5 nM [3H]-CP- 55940

J Med Chem 48: 5813-22 (2005)


Article DOI: 10.1021/jm0502743
BindingDB Entry DOI: 10.7270/Q23X865M
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50123690
PNG
(1-(2,4-Dichloro-phenyl)-5-(4-methoxy-phenyl)-4-met...)
Show SMILES COc1ccc(cc1)-c1c(C)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C23H24Cl2N4O2/c1-15-21(23(30)27-28-12-4-3-5-13-28)26-29(20-11-8-17(24)14-19(20)25)22(15)16-6-9-18(31-2)10-7-16/h6-11,14H,3-5,12-13H2,1-2H3,(H,27,30)
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 4.10n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Binding affinity was determined by using a competition assay with [125 I]- AM251 against rat cannabinoid receptor 1

J Med Chem 46: 642-5 (2003)


Article DOI: 10.1021/jm020157x
BindingDB Entry DOI: 10.7270/Q27M079X
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50123688
PNG
(4-Bromo-1-(2,4-dichloro-phenyl)-5-(4-methoxy-pheny...)
Show SMILES COc1ccc(cc1)-c1c(Br)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCCC1
Show InChI InChI=1S/C23H23BrCl2N4O2/c1-32-17-9-6-15(7-10-17)22-20(24)21(23(31)28-29-12-4-2-3-5-13-29)27-30(22)19-11-8-16(25)14-18(19)26/h6-11,14H,2-5,12-13H2,1H3,(H,28,31)
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 5.20n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Binding affinity was determined by using a competition assay with [125 I]- AM251 against rat cannabinoid receptor 1

J Med Chem 46: 642-5 (2003)


Article DOI: 10.1021/jm020157x
BindingDB Entry DOI: 10.7270/Q27M079X
More data for this
Ligand-Target Pair
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