Compile Data Set for Download or QSAR

Found 35 hits with Last Name = 'pettit' and Initial = 'rk'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50090045 ((2,3-Dihydroxy-4-methoxy-phenyl)-(3,4,5-trimethoxy...) Show SMILES COc1ccc(C(=O)c2cc(OC)c(OC)c(OC)c2)c(O)c1O Show InChI InChI=1S/C17H18O7/c1-21-11-6-5-10(15(19)16(11)20)14(18)9-7-12(22-2)17(24-4)13(8-9)23-3/h5-8,19-20H,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 43: 2731-7 (2000) BindingDB Entry DOI: 10.7270/Q2SX6CFQ
					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50005480 ((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5-	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 43: 2731-7 (2000) BindingDB Entry DOI: 10.7270/Q2SX6CFQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50090044 ((Z)-2',3'-dihydroxy-3,4,4',5-tetramethoxystilbene ...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)c(O)c1O Show InChI InChI=1S/C18H20O6/c1-21-13-8-7-12(16(19)17(13)20)6-5-11-9-14(22-2)18(24-4)15(10-11)23-3/h5-10,19-20H,1-4H3/b6-5-	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 43: 2731-7 (2000) BindingDB Entry DOI: 10.7270/Q2SX6CFQ
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168445 (5-[(Z)-2-(3-Bromo-4-methoxy-phenyl)-vinyl]-1,2,3-t...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1Br Show InChI InChI=1S/C18H19BrO4/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11H,1-4H3/b6-5-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50005480 ((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description The compound was tested for the concentration to inhibit 50% of tubulin polymerization.				J Med Chem 41: 1688-95 (1998) Article DOI: 10.1021/jm970644q BindingDB Entry DOI: 10.7270/Q2N300QZ
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50005480 ((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50006677 (1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1 Show InChI InChI=1S/C18H20O4/c1-19-15-9-7-13(8-10-15)5-6-14-11-16(20-2)18(22-4)17(12-14)21-3/h5-12H,1-4H3/b6-5-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description The compound was tested for the concentration to inhibit 50% of tubulin polymerization.				J Med Chem 41: 1688-95 (1998) Article DOI: 10.1021/jm970644q BindingDB Entry DOI: 10.7270/Q2N300QZ
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM23940 (1,3-dimethoxy-5-[(Z)-2-(4-methoxyphenyl)ethenyl]be...) Show SMILES COc1ccc(\C=C/c2cc(OC)cc(OC)c2)cc1 Show InChI InChI=1S/C17H18O3/c1-18-15-8-6-13(7-9-15)4-5-14-10-16(19-2)12-17(11-14)20-3/h4-12H,1-3H3/b5-4-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization reported as IC50				J Med Chem 45: 2534-42 (2002) Article DOI: 10.1021/jm010119y BindingDB Entry DOI: 10.7270/Q20P12RK
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50005480 ((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization reported as IC50				J Med Chem 45: 2534-42 (2002) Article DOI: 10.1021/jm010119y BindingDB Entry DOI: 10.7270/Q20P12RK
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50473760 (3,4'',5-Trismethoxybenzophenone | CHEMBL86124) Show SMILES COc1ccc(cc1)C(=O)c1cc(OC)cc(OC)c1 Show InChI InChI=1S/C16H16O4/c1-18-13-6-4-11(5-7-13)16(17)12-8-14(19-2)10-15(9-12)20-3/h4-10H,1-3H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization reported as IC50				J Med Chem 45: 2534-42 (2002) Article DOI: 10.1021/jm010119y BindingDB Entry DOI: 10.7270/Q20P12RK
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168443 ((Z)-1-(3',4',5'-trimethoxyphenyl)-2-(3''-nitro-4''...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1[N+]([O-])=O Show InChI InChI=1S/C18H19NO6/c1-22-15-8-7-12(9-14(15)19(20)21)5-6-13-10-16(23-2)18(25-4)17(11-13)24-3/h5-11H,1-4H3/b6-5-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168446 (2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vi...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OCCO Show InChI InChI=1S/C20H24O6/c1-22-16-8-7-14(11-17(16)26-10-9-21)5-6-15-12-18(23-2)20(25-4)19(13-15)24-3/h5-8,11-13,21H,9-10H2,1-4H3/b6-5-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50156812 (PHENSTATIN) Show SMILES COc1ccc(cc1O)C(=O)c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C17H18O6/c1-20-13-6-5-10(7-12(13)18)16(19)11-8-14(21-2)17(23-4)15(9-11)22-3/h5-9,18H,1-4H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization reported as IC50				J Med Chem 45: 2534-42 (2002) Article DOI: 10.1021/jm010119y BindingDB Entry DOI: 10.7270/Q20P12RK
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50471653 (CHEMBL297299) Show SMILES COc1ccc(cc1OC(C)=O)C(=O)c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C19H20O7/c1-11(20)26-15-8-12(6-7-14(15)22-2)18(21)13-9-16(23-3)19(25-5)17(10-13)24-4/h6-10H,1-5H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description The compound was tested for the concentration to inhibit 50% of tubulin polymerization.				J Med Chem 41: 1688-95 (1998) Article DOI: 10.1021/jm970644q BindingDB Entry DOI: 10.7270/Q2N300QZ
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168457 (3-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vi...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OCCCO Show InChI InChI=1S/C21H26O6/c1-23-17-9-8-15(12-18(17)27-11-5-10-22)6-7-16-13-19(24-2)21(26-4)20(14-16)25-3/h6-9,12-14,22H,5,10-11H2,1-4H3/b7-6-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168447 (1-(2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OCCn1ccnc1 Show InChI InChI=1S/C23H26N2O5/c1-26-19-8-7-17(13-20(19)30-12-11-25-10-9-24-16-25)5-6-18-14-21(27-2)23(29-4)22(15-18)28-3/h5-10,13-16H,11-12H2,1-4H3/b6-5-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168454 ((E)-4-(3-hydroxy-4-methoxystyryl)-2,6-dimethoxyphe...) Show SMILES COc1ccc(\C=C\c2cc(OC)c(O)c(OC)c2)cc1O Show InChI InChI=1S/C17H18O5/c1-20-14-7-6-11(8-13(14)18)4-5-12-9-15(21-2)17(19)16(10-12)22-3/h4-10,18-19H,1-3H3/b5-4+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168453 (1-(2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OCCn1cccc1 Show InChI InChI=1S/C24H27NO5/c1-26-20-10-9-18(15-21(20)30-14-13-25-11-5-6-12-25)7-8-19-16-22(27-2)24(29-4)23(17-19)28-3/h5-12,15-17H,13-14H2,1-4H3/b8-7-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50471654 (CHEMBL44574) Show SMILES [Na;v0+].[#6]-[#8]-c1ccc(cc1-[#8]P([#8])([#8-])=O)-[#6](=O)-c1cc(-[#8]-[#6])c(-[#8]-[#6])c(-[#8]-[#6])c1 Show InChI InChI=1S/C17H19O9P/c1-22-12-6-5-10(7-13(12)26-27(19,20)21)16(18)11-8-14(23-2)17(25-4)15(9-11)24-3/h5-9H,1-4H3,(H2,19,20,21)/p-1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description The compound was tested for the concentration to inhibit 50% of tubulin polymerization.				J Med Chem 41: 1688-95 (1998) Article DOI: 10.1021/jm970644q BindingDB Entry DOI: 10.7270/Q2N300QZ
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50473759 (CHEMBL87712) Show SMILES COc1cc(OC)cc(\C=C/c2ccc(O)cc2)c1 Show InChI InChI=1S/C16H16O3/c1-18-15-9-13(10-16(11-15)19-2)4-3-12-5-7-14(17)8-6-12/h3-11,17H,1-2H3/b4-3-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization reported as IC50				J Med Chem 45: 2534-42 (2002) Article DOI: 10.1021/jm010119y BindingDB Entry DOI: 10.7270/Q20P12RK
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168452 (5-[(E)-2-(3-Bromo-4-methoxy-phenyl)-vinyl]-1,2,3-t...) Show SMILES COc1ccc(\C=C\c2cc(OC)c(OC)c(OC)c2)cc1Br Show InChI InChI=1S/C18H19BrO4/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11H,1-4H3/b6-5+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50009561 ((E)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol | 2...) Show SMILES COc1ccc(\C=C\c2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168459 (CHEMBL195691 | Methanesulfonic acid 2-{2-methoxy-5...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OCCOS(C)(=O)=O Show InChI InChI=1S/C21H26O8S/c1-24-17-9-8-15(12-18(17)28-10-11-29-30(5,22)23)6-7-16-13-19(25-2)21(27-4)20(14-16)26-3/h6-9,12-14H,10-11H2,1-5H3/b7-6-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM23926 ((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...) Show SMILES Oc1ccc(\C=C\c2cc(O)cc(O)c2)cc1 Show InChI InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization reported as IC50				J Med Chem 45: 2534-42 (2002) Article DOI: 10.1021/jm010119y BindingDB Entry DOI: 10.7270/Q20P12RK
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168449 (CHEMBL535375 | Diethyl-(2-{2-methoxy-5-[(Z)-2-(3,4...) Show SMILES CCN(CC)CCOc1cc(\C=C/c2cc(OC)c(OC)c(OC)c2)ccc1OC Show InChI InChI=1S/C24H33NO5/c1-7-25(8-2)13-14-30-21-15-18(11-12-20(21)26-3)9-10-19-16-22(27-4)24(29-6)23(17-19)28-5/h9-12,15-17H,7-8,13-14H2,1-6H3/b10-9-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168448 ((2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-v...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OCCN(C)C Show InChI InChI=1S/C22H29NO5/c1-23(2)11-12-28-19-13-16(9-10-18(19)24-3)7-8-17-14-20(25-4)22(27-6)21(15-17)26-5/h7-10,13-15H,11-12H2,1-6H3/b8-7-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168444 (4-(2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OCCN1CCOCC1 Show InChI InChI=1S/C24H31NO6/c1-26-20-8-7-18(15-21(20)31-14-11-25-9-12-30-13-10-25)5-6-19-16-22(27-2)24(29-4)23(17-19)28-3/h5-8,15-17H,9-14H2,1-4H3/b6-5-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50064259 (CHEMBL289351 | Combretastatin A4 phosphate | Di-So...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OP([O-])([O-])=O Show InChI InChI=1S/C18H21O8P/c1-22-14-8-7-12(9-15(14)26-27(19,20)21)5-6-13-10-16(23-2)18(25-4)17(11-13)24-3/h5-11H,1-4H3,(H2,19,20,21)/p-2/b6-5-	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 43: 2731-7 (2000) BindingDB Entry DOI: 10.7270/Q2SX6CFQ
					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50090046 (CHEMBL329267 | Phosphoric acid mono-[3-methoxy-2-p...) Show SMILES COc1ccc(C(=O)c2cc(OC)c(OC)c(OC)c2)c(OP([O-])([O-])=O)c1OP([O-])([O-])=O Show InChI InChI=1S/C17H20O13P2/c1-25-11-6-5-10(15(29-31(19,20)21)17(11)30-32(22,23)24)14(18)9-7-12(26-2)16(28-4)13(8-9)27-3/h5-8H,1-4H3,(H2,19,20,21)(H2,22,23,24)/p-4	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 43: 2731-7 (2000) BindingDB Entry DOI: 10.7270/Q2SX6CFQ
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168456 (Bis-(2-chloro-ethyl)-carbamic acid 2-methoxy-5-[(Z...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OC(=O)N(CCCl)CCCl Show InChI InChI=1S/C23H27Cl2NO6/c1-28-18-8-7-16(13-19(18)32-23(27)26(11-9-24)12-10-25)5-6-17-14-20(29-2)22(31-4)21(15-17)30-3/h5-8,13-15H,9-12H2,1-4H3/b6-5-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168458 (1-(2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OCCN1CCN(C)CC1 Show InChI InChI=1S/C25H34N2O5/c1-26-10-12-27(13-11-26)14-15-32-22-16-19(8-9-21(22)28-2)6-7-20-17-23(29-3)25(31-5)24(18-20)30-4/h6-9,16-18H,10-15H2,1-5H3/b7-6-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168451 (5-{(Z)-2-[3-(2-Chloro-ethoxy)-4-methoxy-phenyl]-vi...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OCCCl Show InChI InChI=1S/C20H23ClO5/c1-22-16-8-7-14(11-17(16)26-10-9-21)5-6-15-12-18(23-2)20(25-4)19(13-15)24-3/h5-8,11-13H,9-10H2,1-4H3/b6-5-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168455 (1-(2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OCCN1CCCC1 Show InChI InChI=1S/C24H31NO5/c1-26-20-10-9-18(15-21(20)30-14-13-25-11-5-6-12-25)7-8-19-16-22(27-2)24(29-4)23(17-19)28-3/h7-10,15-17H,5-6,11-14H2,1-4H3/b8-7-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168450 (1-(2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OCCN1CCCCC1 Show InChI InChI=1S/C25H33NO5/c1-27-21-11-10-19(16-22(21)31-15-14-26-12-6-5-7-13-26)8-9-20-17-23(28-2)25(30-4)24(18-20)29-3/h8-11,16-18H,5-7,12-15H2,1-4H3/b9-8-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50064259 (CHEMBL289351 | Combretastatin A4 phosphate | Di-So...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OP([O-])([O-])=O Show InChI InChI=1S/C18H21O8P/c1-22-14-8-7-12(9-15(14)26-27(19,20)21)5-6-13-10-16(23-2)18(25-4)17(11-13)24-3/h5-11H,1-4H3,(H2,19,20,21)/p-2/b6-5-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description The compound was tested for the concentration to inhibit 50% of tubulin polymerization.				J Med Chem 41: 1688-95 (1998) Article DOI: 10.1021/jm970644q BindingDB Entry DOI: 10.7270/Q2N300QZ
					More data for this Ligand-Target Pair