BindingDB PrimarySearch

Found 8 hits with Last Name = 'phillips' and Initial = 'rs'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Kynureninase (Homo sapiens (Human))	BDBM50109155 (2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric aci...) Show SMILES NC(CC(O)c1cccc(O)c1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Inhibition of human kynureninase				J Med Chem 52: 389-96 (2009) Article DOI: 10.1021/jm8010806 BindingDB Entry DOI: 10.7270/Q2DZ0860
University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatic-L-amino-acid decarboxylase (Sus scrofa)	BDBM50005740 ((+)-1-Amino-2-(3-hydroxy-phenyl)-cyclopropa necarb...) Show SMILES NC1(CC1c1cccc(O)c1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Inhibitory activity of the compound against pig kidney L-aromatic amino acid decarboxylase (Dopamine decarboxylase)				J Med Chem 35: 1410-7 (1992) BindingDB Entry DOI: 10.7270/Q2W094WD
University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatic-L-amino-acid decarboxylase (Sus scrofa)	BDBM50005743 ((-)-1-Amino-2-(3-hydroxy-phenyl)-cyclopropanecarbo...) Show SMILES N[C@]1(C[C@H]1c1cccc(O)c1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Inhibitory activity of the compound against pig kidney L-aromatic amino acid decarboxylase(Dopa decarboxylase)				J Med Chem 35: 1410-7 (1992) BindingDB Entry DOI: 10.7270/Q2W094WD
University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Kynureninase (Homo sapiens (Human))	BDBM50265459 (3-Hydroxyhippuric acid \| CHEMBL447627) Show SMILES OC(=O)CNC(=O)c1cccc(O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Inhibition of human kynureninase				J Med Chem 52: 389-96 (2009) Article DOI: 10.1021/jm8010806 BindingDB Entry DOI: 10.7270/Q2DZ0860
University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Aromatic-L-amino-acid decarboxylase (Sus scrofa)	BDBM50005741 ((+)-1-Amino-2-(3-hydroxy-phenyl)-cyclopropanecarbo...) Show SMILES N[C@@]1(C[C@@H]1c1cccc(O)c1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	3.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Inhibitory activity of the compound against pig kidney L-aromatic amino acid decarboxylase (Dopa decarboxylase)				J Med Chem 35: 1410-7 (1992) BindingDB Entry DOI: 10.7270/Q2W094WD
University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatic-L-amino-acid decarboxylase (Sus scrofa)	BDBM50005740 ((+)-1-Amino-2-(3-hydroxy-phenyl)-cyclopropa necarb...) Show SMILES NC1(CC1c1cccc(O)c1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	6.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Inhibitory activity of the compound against pig kidney L-aromatic amino acid decarboxylase(Dopa decarboxylase)				J Med Chem 35: 1410-7 (1992) BindingDB Entry DOI: 10.7270/Q2W094WD
University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatic-L-amino-acid decarboxylase (Sus scrofa)	BDBM50005742 ((+)-D-m-Tyrosine2-Amino-3-(3-hydroxy-phenyl)-2-met...) Show SMILES C[C@](N)(Cc1cccc(O)c1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Inhibitory activity of the compound against pig kidney L-aromatic amino acid decarboxylase (Dopamine decarboxylase)				J Med Chem 35: 1410-7 (1992) BindingDB Entry DOI: 10.7270/Q2W094WD
University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Kynurenine 3-monooxygenase (Homo sapiens (Human))	BDBM50061916 (3,4-Dimethoxy-N-[4-(3-nitro-phenyl)-thiazol-2-yl]-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Inhibition of KMO (unknown origin)				Bioorg Med Chem Lett 27: 1705-1708 (2017) Article DOI: 10.1016/j.bmcl.2017.02.080 BindingDB Entry DOI: 10.7270/Q2154K97
University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair