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Compile Data Set for Download or QSAR

Found 384 hits with Last Name = 'rémillard' and Initial = 'r'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175968
PNG
(US10047103, 1 | US9688695, 1)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(C)n3)cc(OC)cc2o1
Show InChI InChI=1S/C19H16N4O4S2/c1-10-20-11(9-28-10)8-26-15-4-12(24-2)5-16-13(15)6-17(27-16)14-7-23-18(21-14)29-19(22-23)25-3/h4-7,9H,8H2,1-3H3
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n/an/an/an/a 1.80n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175969
PNG
(US10047103, 2 | US9605024, Example 2 | US9688695, ...)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)C(F)(F)F)cc(OC)cc2o1
Show InChI InChI=1S/C19H13F3N4O4S2/c1-27-10-3-13(29-7-9-8-31-16(23-9)19(20,21)22)11-5-15(30-14(11)4-10)12-6-26-17(24-12)32-18(25-26)28-2/h3-6,8H,7H2,1-2H3
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n/an/an/an/a 0.420n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175970
PNG
(US10047103, 3 | US9605024, Example 3 | US9688695, ...)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccccc3)cc(OC)cc2o1
Show InChI InChI=1S/C24H18N4O4S2/c1-29-16-8-19(31-12-15-13-33-22(25-15)14-6-4-3-5-7-14)17-10-21(32-20(17)9-16)18-11-28-23(26-18)34-24(27-28)30-2/h3-11,13H,12H2,1-2H3
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n/an/an/an/a 0.320n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175971
PNG
(US10047103, 4 | US9688695, 4)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nc(cs3)-c3ccccc3)cc(OC)cc2o1
Show InChI InChI=1S/C24H18N4O4S2/c1-29-15-8-19(31-12-22-25-18(13-33-22)14-6-4-3-5-7-14)16-10-21(32-20(16)9-15)17-11-28-23(26-17)34-24(27-28)30-2/h3-11,13H,12H2,1-2H3
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n/an/an/an/a 1.10n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175972
PNG
(US10047103, 5 | US9688695, 5)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)N3CCOCC3)cc(OC)cc2o1
Show InChI InChI=1S/C22H21N5O5S2/c1-28-14-7-17(31-11-13-12-33-20(23-13)26-3-5-30-6-4-26)15-9-19(32-18(15)8-14)16-10-27-21(24-16)34-22(25-27)29-2/h7-10,12H,3-6,11H2,1-2H3
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n/an/an/an/a 0.610n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175973
PNG
(US10047103, 6 | US9688695, 6)
Show SMILES COCCOCc1nc(COc2cc(OC)cc3oc(cc23)-c2cn3nc(OC)sc3n2)cs1
Show InChI InChI=1S/C22H22N4O6S2/c1-27-4-5-30-11-20-23-13(12-33-20)10-31-17-6-14(28-2)7-18-15(17)8-19(32-18)16-9-26-21(24-16)34-22(25-26)29-3/h6-9,12H,4-5,10-11H2,1-3H3
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n/an/an/an/a 0.680n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175974
PNG
(US10047103, 7 | US9688695, 7)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nsc(n3)-c3ccccc3)cc(OC)cc2o1
Show InChI InChI=1S/C23H17N5O4S2/c1-29-14-8-17(31-12-20-25-21(34-27-20)13-6-4-3-5-7-13)15-10-19(32-18(15)9-14)16-11-28-22(24-16)33-23(26-28)30-2/h3-11H,12H2,1-2H3
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n/an/an/an/a 1.5n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175975
PNG
(US10047103, 8 | US9605024, Example 8 | US9688695, ...)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nnc(s3)-c3ccccc3)cc(OC)cc2o1
Show InChI InChI=1S/C23H17N5O4S2/c1-29-14-8-17(31-12-20-25-26-21(33-20)13-6-4-3-5-7-13)15-10-19(32-18(15)9-14)16-11-28-22(24-16)34-23(27-28)30-2/h3-11H,12H2,1-2H3
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n/an/an/an/a 3.90n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175976
PNG
(US10047103, 9 | US9605024, Example 9 | US9688695, ...)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cn(nn3)-c3ccccc3)cc(OC)cc2o1
Show InChI InChI=1S/C23H18N6O4S/c1-30-16-8-19(32-13-14-11-28(27-25-14)15-6-4-3-5-7-15)17-10-21(33-20(17)9-16)18-12-29-22(24-18)34-23(26-29)31-2/h3-12H,13H2,1-2H3
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n/an/an/an/a 5.30n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175977
PNG
(US10047103, 10 | US9605024, Example 10 | US9688695...)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cnnn3-c3ccccc3)cc(OC)cc2o1
Show InChI InChI=1S/C23H18N6O4S/c1-30-16-8-19(32-13-15-11-24-27-29(15)14-6-4-3-5-7-14)17-10-21(33-20(17)9-16)18-12-28-22(25-18)34-23(26-28)31-2/h3-12H,13H2,1-2H3
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n/an/an/an/a 3.5n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175978
PNG
(US10047103, 11 | US9688695, 11)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccc(cc3)C(F)(F)F)cc(OC)cc2o1
Show InChI InChI=1S/C25H17F3N4O4S2/c1-33-16-7-19(35-11-15-12-37-22(29-15)13-3-5-14(6-4-13)25(26,27)28)17-9-21(36-20(17)8-16)18-10-32-23(30-18)38-24(31-32)34-2/h3-10,12H,11H2,1-2H3
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n/an/an/an/a 1.30n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175979
PNG
(US10047103, 12 | US9688695, 12)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3cccc(C)c3)cc(OC)cc2o1
Show InChI InChI=1S/C25H20N4O4S2/c1-14-5-4-6-15(7-14)23-26-16(13-34-23)12-32-20-8-17(30-2)9-21-18(20)10-22(33-21)19-11-29-24(27-19)35-25(28-29)31-3/h4-11,13H,12H2,1-3H3
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n/an/an/an/a 1.30n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175980
PNG
(US10047103, 13 | US9688695, 13)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nc(sc3C)-c3ccccc3)cc(OC)cc2o1
Show InChI InChI=1S/C25H20N4O4S2/c1-14-19(26-23(34-14)15-7-5-4-6-8-15)13-32-20-9-16(30-2)10-21-17(20)11-22(33-21)18-12-29-24(27-18)35-25(28-29)31-3/h4-12H,13H2,1-3H3
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n/an/an/an/a 2.10n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175981
PNG
(US10047103, 14 | US9688695, 14)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)C3CCOCC3)cc(OC)cc2o1
Show InChI InChI=1S/C23H22N4O5S2/c1-28-15-7-18(31-11-14-12-33-21(24-14)13-3-5-30-6-4-13)16-9-20(32-19(16)8-15)17-10-27-22(25-17)34-23(26-27)29-2/h7-10,12-13H,3-6,11H2,1-2H3
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n/an/an/an/a 1.20n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175982
PNG
(US10047103, 15 | US9688695, 15)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccc(F)cc3)cc(OC)cc2o1
Show InChI InChI=1S/C24H17FN4O4S2/c1-30-16-7-19(32-11-15-12-34-22(26-15)13-3-5-14(25)6-4-13)17-9-21(33-20(17)8-16)18-10-29-23(27-18)35-24(28-29)31-2/h3-10,12H,11H2,1-2H3
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n/an/an/an/a 0.980n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175983
PNG
(US10047103, 16 | US9688695, 16)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccccc3Cl)cc(OC)cc2o1
Show InChI InChI=1S/C24H17ClN4O4S2/c1-30-14-7-19(32-11-13-12-34-22(26-13)15-5-3-4-6-17(15)25)16-9-21(33-20(16)8-14)18-10-29-23(27-18)35-24(28-29)31-2/h3-10,12H,11H2,1-2H3
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n/an/an/an/a 3.40n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175984
PNG
(US10047103, 17 | US9688695, 17)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3cccc(c3)C(F)(F)F)cc(OC)cc2o1
Show InChI InChI=1S/C25H17F3N4O4S2/c1-33-16-7-19(35-11-15-12-37-22(29-15)13-4-3-5-14(6-13)25(26,27)28)17-9-21(36-20(17)8-16)18-10-32-23(30-18)38-24(31-32)34-2/h3-10,12H,11H2,1-2H3
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n/an/an/an/a 1.10n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175985
PNG
(US10047103, 18 | US9605024, Example 18 | US9688695...)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccc(OC)cc3)cc(OC)cc2o1
Show InChI InChI=1S/C25H20N4O5S2/c1-30-16-6-4-14(5-7-16)23-26-15(13-35-23)12-33-20-8-17(31-2)9-21-18(20)10-22(34-21)19-11-29-24(27-19)36-25(28-29)32-3/h4-11,13H,12H2,1-3H3
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n/an/an/an/a 2.5n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175986
PNG
(US10047103, 19 | US9688695, 19)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccccc3OC)cc(OC)cc2o1
Show InChI InChI=1S/C25H20N4O5S2/c1-30-15-8-20(33-12-14-13-35-23(26-14)16-6-4-5-7-19(16)31-2)17-10-22(34-21(17)9-15)18-11-29-24(27-18)36-25(28-29)32-3/h4-11,13H,12H2,1-3H3
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n/an/an/an/a 1n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175987
PNG
(US10047103, 20 | US9688695, 20)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)C3CCCCC3)cc(OC)cc2o1
Show InChI InChI=1S/C24H24N4O4S2/c1-29-16-8-19(31-12-15-13-33-22(25-15)14-6-4-3-5-7-14)17-10-21(32-20(17)9-16)18-11-28-23(26-18)34-24(27-28)30-2/h8-11,13-14H,3-7,12H2,1-2H3
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n/an/an/an/a 1.10n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175988
PNG
(US10047103, 21 | US9688695, 21)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)N3CCCCC3)cc(OC)cc2o1
Show InChI InChI=1S/C23H23N5O4S2/c1-29-15-8-18(31-12-14-13-33-21(24-14)27-6-4-3-5-7-27)16-10-20(32-19(16)9-15)17-11-28-22(25-17)34-23(26-28)30-2/h8-11,13H,3-7,12H2,1-2H3
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n/an/an/an/a 0.430n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175989
PNG
(US10047103, 22 | US9688695, 22)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)N3CCN(C)CC3)cc(OC)cc2o1
Show InChI InChI=1S/C23H24N6O4S2/c1-27-4-6-28(7-5-27)21-24-14(13-34-21)12-32-18-8-15(30-2)9-19-16(18)10-20(33-19)17-11-29-22(25-17)35-23(26-29)31-3/h8-11,13H,4-7,12H2,1-3H3
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n/an/an/an/a 0.690n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175990
PNG
(US10047103, 23 | US9688695, 23)
Show SMILES CCc1nc(COc2cc(OC)cc3oc(cc23)-c2cn3nc(OC)sc3n2)cs1
Show InChI InChI=1S/C20H18N4O4S2/c1-4-18-21-11(10-29-18)9-27-15-5-12(25-2)6-16-13(15)7-17(28-16)14-8-24-19(22-14)30-20(23-24)26-3/h5-8,10H,4,9H2,1-3H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175991
PNG
(US10047103, 24 | US9688695, 24)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccc(F)cc3F)cc(OC)cc2o1
Show InChI InChI=1S/C24H16F2N4O4S2/c1-31-14-6-19(33-10-13-11-35-22(27-13)15-4-3-12(25)5-17(15)26)16-8-21(34-20(16)7-14)18-9-30-23(28-18)36-24(29-30)32-2/h3-9,11H,10H2,1-2H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175992
PNG
(US10047103, 25 | US9688695, 25)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3cccc(F)c3)cc(OC)cc2o1
Show InChI InChI=1S/C24H17FN4O4S2/c1-30-16-7-19(32-11-15-12-34-22(26-15)13-4-3-5-14(25)6-13)17-9-21(33-20(17)8-16)18-10-29-23(27-18)35-24(28-29)31-2/h3-10,12H,11H2,1-2H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175993
PNG
(US10047103, 26 | US9688695, 26)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccccc3F)cc(OC)cc2o1
Show InChI InChI=1S/C24H17FN4O4S2/c1-30-14-7-19(32-11-13-12-34-22(26-13)15-5-3-4-6-17(15)25)16-9-21(33-20(16)8-14)18-10-29-23(27-18)35-24(28-29)31-2/h3-10,12H,11H2,1-2H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175994
PNG
(US10047103, 27 | US9688695, 27)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccc(Cl)cc3)cc(OC)cc2o1
Show InChI InChI=1S/C24H17ClN4O4S2/c1-30-16-7-19(32-11-15-12-34-22(26-15)13-3-5-14(25)6-4-13)17-9-21(33-20(17)8-16)18-10-29-23(27-18)35-24(28-29)31-2/h3-10,12H,11H2,1-2H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175995
PNG
(US10047103, 75 | US9605024, Example 28 | US9688695...)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccncc3)cc(OC)cc2o1
Show InChI InChI=1S/C23H17N5O4S2/c1-29-15-7-18(31-11-14-12-33-21(25-14)13-3-5-24-6-4-13)16-9-20(32-19(16)8-15)17-10-28-22(26-17)34-23(27-28)30-2/h3-10,12H,11H2,1-2H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175996
PNG
(US10047103, 29 | US9688695, 29)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccc(OC(F)(F)F)cc3)cc(OC)cc2o1
Show InChI InChI=1S/C25H17F3N4O5S2/c1-33-16-7-19(17-9-21(36-20(17)8-16)18-10-32-23(30-18)39-24(31-32)34-2)35-11-14-12-38-22(29-14)13-3-5-15(6-4-13)37-25(26,27)28/h3-10,12H,11H2,1-2H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175997
PNG
(US10047103, 82 | US9688695, 30 | US9688695, 82)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3cccnc3)cc(OC)cc2o1
Show InChI InChI=1S/C23H17N5O4S2/c1-29-15-6-18(31-11-14-12-33-21(25-14)13-4-3-5-24-9-13)16-8-20(32-19(16)7-15)17-10-28-22(26-17)34-23(27-28)30-2/h3-10,12H,11H2,1-2H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175998
PNG
(US10047103, 31 | US9688695, 31)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)N3CCC(F)(F)CC3)cc(OC)cc2o1
Show InChI InChI=1S/C23H21F2N5O4S2/c1-31-14-7-17(33-11-13-12-35-20(26-13)29-5-3-23(24,25)4-6-29)15-9-19(34-18(15)8-14)16-10-30-21(27-16)36-22(28-30)32-2/h7-10,12H,3-6,11H2,1-2H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM175999
PNG
(US10047103, 32 | US9688695, 32)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3cnccn3)cc(OC)cc2o1
Show InChI InChI=1S/C22H16N6O4S2/c1-29-13-5-17(31-10-12-11-33-20(25-12)15-8-23-3-4-24-15)14-7-19(32-18(14)6-13)16-9-28-21(26-16)34-22(27-28)30-2/h3-9,11H,10H2,1-2H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176000
PNG
(US10047103, 33 | US9605024, Example 33 | US9688695...)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3cc(C)on3)cc(OC)cc2o1
Show InChI InChI=1S/C22H17N5O5S2/c1-11-4-15(26-32-11)20-23-12(10-33-20)9-30-17-5-13(28-2)6-18-14(17)7-19(31-18)16-8-27-21(24-16)34-22(25-27)29-3/h4-8,10H,9H2,1-3H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176001
PNG
(US10047103, 34 | US9688695, 34)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cscn3)cc(OC)cc2o1
Show InChI InChI=1S/C18H14N4O4S2/c1-23-11-3-14(25-7-10-8-27-9-19-10)12-5-16(26-15(12)4-11)13-6-22-17(20-13)28-18(21-22)24-2/h3-6,8-9H,7H2,1-2H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176002
PNG
(US10047103, 35 | US9688695, 35)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(Br)n3)cc(OC)cc2o1
Show InChI InChI=1S/C18H13BrN4O4S2/c1-24-10-3-13(26-7-9-8-28-16(19)20-9)11-5-15(27-14(11)4-10)12-6-23-17(21-12)29-18(22-23)25-2/h3-6,8H,7H2,1-2H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176003
PNG
(US10047103, 36 | US9688695, 36)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccc(cc3)C(=O)N(C)C)cc(OC)cc2o1
Show InChI InChI=1S/C27H23N5O5S2/c1-31(2)25(33)16-7-5-15(6-8-16)24-28-17(14-38-24)13-36-21-9-18(34-3)10-22-19(21)11-23(37-22)20-12-32-26(29-20)39-27(30-32)35-4/h5-12,14H,13H2,1-4H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176004
PNG
(US10047103, 37 | US9688695, 37)
Show SMILES COC(=O)c1ccc(cc1)-c1nc(COc2cc(OC)cc3oc(cc23)-c2cn3nc(OC)sc3n2)cs1
Show InChI InChI=1S/C26H20N4O6S2/c1-32-17-8-20(35-12-16-13-37-23(27-16)14-4-6-15(7-5-14)24(31)33-2)18-10-22(36-21(18)9-17)19-11-30-25(28-19)38-26(29-30)34-3/h4-11,13H,12H2,1-3H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176005
PNG
(US10047103, 38 | US9688695, 38)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccc(cc3)C(C)(C)O)cc(OC)cc2o1
Show InChI InChI=1S/C27H24N4O5S2/c1-27(2,32)16-7-5-15(6-8-16)24-28-17(14-37-24)13-35-21-9-18(33-3)10-22-19(21)11-23(36-22)20-12-31-25(29-20)38-26(30-31)34-4/h5-12,14,32H,13H2,1-4H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176006
PNG
(US10047103, 39 | US9688695, 39)
Show SMILES COCCN(C)C(=O)c1ccc(cc1)-c1nc(COc2cc(OC)cc3oc(cc23)-c2cn3nc(OC)sc3n2)cs1
Show InChI InChI=1S/C29H27N5O6S2/c1-33(9-10-36-2)27(35)18-7-5-17(6-8-18)26-30-19(16-41-26)15-39-23-11-20(37-3)12-24-21(23)13-25(40-24)22-14-34-28(31-22)42-29(32-34)38-4/h5-8,11-14,16H,9-10,15H2,1-4H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176007
PNG
(US10047103, 40 | US9688695, 40)
Show SMILES CNC(=O)c1ccc(cc1)-c1nc(COc2cc(OC)cc3oc(cc23)-c2cn3nc(OC)sc3n2)cs1
Show InChI InChI=1S/C26H21N5O5S2/c1-27-23(32)14-4-6-15(7-5-14)24-28-16(13-37-24)12-35-20-8-17(33-2)9-21-18(20)10-22(36-21)19-11-31-25(29-19)38-26(30-31)34-3/h4-11,13H,12H2,1-3H3,(H,27,32)
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n/an/an/an/a 0.260n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176008
PNG
(US10047103, 41 | US9688695, 41)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccc(cc3)C(=O)NC(C)(C)C)cc(OC)cc2o1
Show InChI InChI=1S/C29H27N5O5S2/c1-29(2,3)32-25(35)16-6-8-17(9-7-16)26-30-18(15-40-26)14-38-22-10-19(36-4)11-23-20(22)12-24(39-23)21-13-34-27(31-21)41-28(33-34)37-5/h6-13,15H,14H2,1-5H3,(H,32,35)
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n/an/an/an/a 0.900n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176009
PNG
(US10047103, 42 | US9688695, 42)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nc(sc3C(C)C)-c3ccc(cc3)C(=O)N(C)C)cc(OC)cc2o1
Show InChI InChI=1S/C30H29N5O5S2/c1-16(2)26-22(31-27(41-26)17-7-9-18(10-8-17)28(36)34(3)4)15-39-23-11-19(37-5)12-24-20(23)13-25(40-24)21-14-35-29(32-21)42-30(33-35)38-6/h7-14,16H,15H2,1-6H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176010
PNG
(US10047103, 43 | US9688695, 43)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nc(sc3C(C)C)-c3ccnc(F)c3)cc(OC)cc2o1
Show InChI InChI=1S/C26H22FN5O4S2/c1-13(2)23-18(29-24(37-23)14-5-6-28-22(27)7-14)12-35-19-8-15(33-3)9-20-16(19)10-21(36-20)17-11-32-25(30-17)38-26(31-32)34-4/h5-11,13H,12H2,1-4H3
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n/an/an/an/a 0.340n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176011
PNG
(US10047103, 44 | US9688695, 44)
Show SMILES CCc1sc(nc1COc1cc(OC)cc2oc(cc12)-c1cn2nc(OC)sc2n1)-c1ccc(cc1)C(=O)N(C)C
Show InChI InChI=1S/C29H27N5O5S2/c1-6-25-21(30-26(40-25)16-7-9-17(10-8-16)27(35)33(2)3)15-38-22-11-18(36-4)12-23-19(22)13-24(39-23)20-14-34-28(31-20)41-29(32-34)37-5/h7-14H,6,15H2,1-5H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176012
PNG
(US10047103, 45 | US9688695, 45)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nc(sc3C)-c3ccc(cc3)C(=O)OC(C)(C)C)cc(OC)cc2o1
Show InChI InChI=1S/C30H28N4O6S2/c1-16-22(31-26(41-16)17-7-9-18(10-8-17)27(35)40-30(2,3)4)15-38-23-11-19(36-5)12-24-20(23)13-25(39-24)21-14-34-28(32-21)42-29(33-34)37-6/h7-14H,15H2,1-6H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176013
PNG
(US10047103, 46 | US9688695, 46)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nc(sc3C)-c3ccc(cc3)C(O)=O)cc(OC)cc2o1
Show InChI InChI=1S/C26H20N4O6S2/c1-13-19(27-23(37-13)14-4-6-15(7-5-14)24(31)32)12-35-20-8-16(33-2)9-21-17(20)10-22(36-21)18-11-30-25(28-18)38-26(29-30)34-3/h4-11H,12H2,1-3H3,(H,31,32)
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176014
PNG
(US10047103, 47 | US9688695, 47)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nc(sc3C)-c3ccc(cc3)C(=O)NCC(F)(F)F)cc(OC)cc2o1
Show InChI InChI=1S/C28H22F3N5O5S2/c1-14-20(33-25(42-14)16-6-4-15(5-7-16)24(37)32-13-28(29,30)31)12-40-21-8-17(38-2)9-22-18(21)10-23(41-22)19-11-36-26(34-19)43-27(35-36)39-3/h4-11H,12-13H2,1-3H3,(H,32,37)
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176015
PNG
(US10047103, 48 | US9688695, 48)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nc(sc3C)-c3ccc(cc3)C(=O)N(C)CC#N)cc(OC)cc2o1
Show InChI InChI=1S/C29H24N6O5S2/c1-16-22(31-26(41-16)17-5-7-18(8-6-17)27(36)34(2)10-9-30)15-39-23-11-19(37-3)12-24-20(23)13-25(40-24)21-14-35-28(32-21)42-29(33-35)38-4/h5-8,11-14H,10,15H2,1-4H3
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176016
PNG
(US10047103, 49 | US9688695, 49)
Show SMILES CNC(=O)c1ccc(cc1)-c1nc(COc2cc(OC)cc3oc(cc23)-c2cn3nc(OC)sc3n2)c(C)s1
Show InChI InChI=1S/C27H23N5O5S2/c1-14-20(29-25(38-14)16-7-5-15(6-8-16)24(33)28-2)13-36-21-9-17(34-3)10-22-18(21)11-23(37-22)19-12-32-26(30-19)39-27(31-32)35-4/h5-12H,13H2,1-4H3,(H,28,33)
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BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens (Human))
BDBM176017
PNG
(US10047103, 50 | US9688695, 50)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(CC(C)C)n3)cc(OC)cc2o1
Show InChI InChI=1S/C22H22N4O4S2/c1-12(2)5-20-23-13(11-31-20)10-29-17-6-14(27-3)7-18-15(17)8-19(30-18)16-9-26-21(24-16)32-22(25-26)28-4/h6-9,11-12H,5,10H2,1-4H3
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n/an/an/an/a 0.210n/an/an/a25



BRISTOL-MYERS SQUIBB COMPANY

US Patent


Assay Description
Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...


US Patent US9688695 (2017)


BindingDB Entry DOI: 10.7270/Q28K777N
More data for this
Ligand-Target Pair
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