Compile Data Set for Download or QSAR

Found 112 hits with Last Name = 'rademacher' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Myelin-associated glycoprotein (Homo sapiens (Human))	BDBM50354062 (CHEMBL1836190) Show SMILES COC(=O)[C@@H](NC(C)=O)[C@@H](C)O[C@H]1O[C@H](CO[C@@]2(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O2)[C@H](O)[C@H](O)CNC(=O)c2ccc(F)cc2)C([O-])=O)[C@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O3)[C@H](O)[C@H](O)CO)C([O-])=O)[C@H]2O)[C@H]1NC(C)=O |r| Show InChI InChI=1S/C50H74FN5O30/c1-17(30(44(73)78-6)53-18(2)59)80-45-33(56-21(5)62)39(83-46-38(71)42(36(69)28(15-58)81-46)86-50(48(76)77)12-25(64)32(55-20(4)61)41(85-50)35(68)27(66)14-57)37(70)29(82-45)16-79-49(47(74)75)11-24(63)31(54-19(3)60)40(84-49)34(67)26(65)13-52-43(72)22-7-9-23(51)10-8-22/h7-10,17,24-42,45-46,57-58,63-71H,11-16H2,1-6H3,(H,52,72)(H,53,59)(H,54,60)(H,55,61)(H,56,62)(H,74,75)(H,76,77)/p-2/t17-,24+,25+,26-,27-,28-,29-,30+,31-,32-,33-,34-,35-,36+,37+,38-,39-,40-,41-,42+,45+,46+,49-,50+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...				Bioorg Med Chem Lett 21: 5045-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.068 BindingDB Entry DOI: 10.7270/Q2WD40ZW
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556732 (CHEMBL4750435) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3ccc(=O)oc3c2)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50342004 (4-(2-(3-(4-nitrophenyl)-5-oxo-1-phenyl-1H-pyrazol-...) Show SMILES OS(=O)(=O)c1ccc(cc1)N=Nc1c([nH]n(-c2ccccc2)c1=O)-c1ccc(cc1)[N+]([O-])=O |w:10.10| Show InChI InChI=1S/C21H15N5O6S/c27-21-20(23-22-15-8-12-18(13-9-15)33(30,31)32)19(14-6-10-17(11-7-14)26(28)29)24-25(21)16-4-2-1-3-5-16/h1-13,24H,(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556755 (CHEMBL4763014) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc(cc2)C(O)=O)c2cc(cnc12)-c1ccc2nonc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556754 (CHEMBL4781443) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3nonc3c2)c2cc(cnc12)-c1ccc(NS(C)(=O)=O)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Myelin-associated glycoprotein (Homo sapiens (Human))	BDBM50354056 (CHEMBL1836336) Show SMILES COC(=O)[C@@H](NC(C)=O)[C@@H](C)O[C@H]1O[C@H](CO)[C@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O3)[C@H](O)[C@H](O)CNC(=O)c3ccc(F)cc3)C([O-])=O)[C@H]2O)[C@H]1NC(C)=O |r| Show InChI InChI=1S/C39H57FN4O22/c1-14(24(35(57)60-5)42-15(2)47)61-36-26(44-17(4)49)31(28(53)22(12-45)62-36)64-37-30(55)33(29(54)23(13-46)63-37)66-39(38(58)59)10-20(50)25(43-16(3)48)32(65-39)27(52)21(51)11-41-34(56)18-6-8-19(40)9-7-18/h6-9,14,20-33,36-37,45-46,50-55H,10-13H2,1-5H3,(H,41,56)(H,42,47)(H,43,48)(H,44,49)(H,58,59)/p-1/t14-,20+,21-,22-,23-,24+,25-,26-,27-,28+,29+,30-,31-,32-,33+,36+,37+,39+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...				Bioorg Med Chem Lett 21: 5045-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.068 BindingDB Entry DOI: 10.7270/Q2WD40ZW
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556737 (CHEMBL4742016) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc(cc2)C(F)(F)F)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 7 (Homo sapiens (Human))	BDBM50556732 (CHEMBL4750435) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3ccc(=O)oc3c2)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PTPN7 (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP assa...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 6 (Homo sapiens (Human))	BDBM50556732 (CHEMBL4750435) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3ccc(=O)oc3c2)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PTPN6 (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP assa...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556733 (CHEMBL4755222) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc(cc2)[N+]([O-])=O)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 12 (Homo sapiens (Human))	BDBM50556732 (CHEMBL4750435) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3ccc(=O)oc3c2)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PTPN12 (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556748 (CHEMBL4741433) Show SMILES OC(=O)c1ccc(cc1)-c1cnc2n(cc(-c3ccc4nonc4c3)c2c1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (Bos taurus)	BDBM50556732 (CHEMBL4750435) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3ccc(=O)oc3c2)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PP2A alpha (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556735 (CHEMBL4747136) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3nonc3c2)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Myelin-associated glycoprotein (Homo sapiens (Human))	BDBM50354049 (CHEMBL1836306) Show SMILES C[C@@H](O[C@H]1O[C@H](CO[C@@]2(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O2)[C@H](O)[C@H](O)CO)C([O-])=O)[C@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O3)[C@H](O)[C@H](O)CO)C([O-])=O)[C@H]2O)[C@H]1NC(C)=O)[C@H](N)C(O)=O |r| Show InChI InChI=1S/C40H66N4O29/c1-11(21(41)34(60)61)67-35-24(44-14(4)50)30(28(58)20(69-35)10-66-39(37(62)63)5-15(51)22(42-12(2)48)31(71-39)25(55)17(53)7-45)70-36-29(59)33(27(57)19(9-47)68-36)73-40(38(64)65)6-16(52)23(43-13(3)49)32(72-40)26(56)18(54)8-46/h11,15-33,35-36,45-47,51-59H,5-10,41H2,1-4H3,(H,42,48)(H,43,49)(H,44,50)(H,60,61)(H,62,63)(H,64,65)/p-2/t11-,15+,16+,17-,18-,19-,20-,21+,22-,23-,24-,25-,26-,27+,28+,29-,30-,31-,32-,33+,35+,36+,39-,40+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAG				Bioorg Med Chem Lett 21: 5045-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.068 BindingDB Entry DOI: 10.7270/Q2WD40ZW
					More data for this Ligand-Target Pair
Myelin-associated glycoprotein (Homo sapiens (Human))	BDBM50354061 (CHEMBL1836340) Show SMILES COC(=O)[C@@H](NC(C)=O)[C@@H](C)O[C@H]1O[C@H](CO[C@@]2(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O2)[C@H](O)[C@H](O)CO)C([O-])=O)[C@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O3)[C@H](O)[C@H](O)CNC(=O)c3ccc(F)cc3)C([O-])=O)[C@H]2O)[C@H]1NC(C)=O |r| Show InChI InChI=1S/C50H74FN5O30/c1-17(30(44(73)78-6)53-18(2)59)80-45-33(56-21(5)62)39(37(70)29(82-45)16-79-49(47(74)75)11-24(63)31(54-19(3)60)41(84-49)35(68)27(66)14-57)83-46-38(71)42(36(69)28(15-58)81-46)86-50(48(76)77)12-25(64)32(55-20(4)61)40(85-50)34(67)26(65)13-52-43(72)22-7-9-23(51)10-8-22/h7-10,17,24-42,45-46,57-58,63-71H,11-16H2,1-6H3,(H,52,72)(H,53,59)(H,54,60)(H,55,61)(H,56,62)(H,74,75)(H,76,77)/p-2/t17-,24+,25+,26-,27-,28-,29-,30+,31-,32-,33-,34-,35-,36+,37+,38-,39-,40-,41-,42+,45+,46+,49-,50+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...				Bioorg Med Chem Lett 21: 5045-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.068 BindingDB Entry DOI: 10.7270/Q2WD40ZW
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556743 (CHEMBL4783825) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc(cc2)C#N)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50342003 (CHEMBL501993 | NSC-87877 | disodium 8-hydroxy-7-[(...) Show SMILES Oc1c(cc(c2cccnc12)S([O-])(=O)=O)N=Nc1ccc2cc(ccc2c1)S([O-])(=O)=O |w:15.16| Show InChI InChI=1S/C19H13N3O7S2/c23-19-16(10-17(31(27,28)29)15-2-1-7-20-18(15)19)22-21-13-5-3-12-9-14(30(24,25)26)6-4-11(12)8-13/h1-10,23H,(H,24,25,26)(H,27,28,29)/p-2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556736 (CHEMBL4749307) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3nonc3c2)c2cc(cnc12)-c1cccc(c1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556734 (CHEMBL4795725) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc(cc2)[N+]([O-])=O)c2cc(cnc12)-c1cccc(c1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50556732 (CHEMBL4750435) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3ccc(=O)oc3c2)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PTPN1 (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP assa...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556730 (CHEMBL4777804) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3C(=O)OCc3c2)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 20 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Myelin-associated glycoprotein (Homo sapiens (Human))	BDBM50354055 (CHEMBL1836335) Show SMILES COC(=O)[C@@H](NC(C)=O)[C@@H](C)O[C@H]1O[C@H](CO)[C@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O3)[C@H](O)[C@H](O)CNC(=O)c3ccc(Cl)cc3)C([O-])=O)[C@H]2O)[C@H]1NC(C)=O |r| Show InChI InChI=1S/C39H57ClN4O22/c1-14(24(35(57)60-5)42-15(2)47)61-36-26(44-17(4)49)31(28(53)22(12-45)62-36)64-37-30(55)33(29(54)23(13-46)63-37)66-39(38(58)59)10-20(50)25(43-16(3)48)32(65-39)27(52)21(51)11-41-34(56)18-6-8-19(40)9-7-18/h6-9,14,20-33,36-37,45-46,50-55H,10-13H2,1-5H3,(H,41,56)(H,42,47)(H,43,48)(H,44,49)(H,58,59)/p-1/t14-,20+,21-,22-,23-,24+,25-,26-,27-,28+,29+,30-,31-,32-,33+,36+,37+,39+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...				Bioorg Med Chem Lett 21: 5045-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.068 BindingDB Entry DOI: 10.7270/Q2WD40ZW
					More data for this Ligand-Target Pair
Myelin-associated glycoprotein (Homo sapiens (Human))	BDBM50354058 (CHEMBL1836337) Show SMILES COC(=O)[C@@H](NC(C)=O)[C@@H](C)O[C@H]1O[C@H](CO[C@@]2(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O2)[C@H](O)[C@H](O)CNC(=O)c2ccc(Cl)cc2)C([O-])=O)[C@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H]1NC(C)=O |r| Show InChI InChI=1S/C39H57ClN4O22/c1-14(24(35(57)60-5)42-15(2)46)62-36-26(44-17(4)48)32(65-37-31(55)30(54)28(52)22(12-45)63-37)29(53)23(64-36)13-61-39(38(58)59)10-20(49)25(43-16(3)47)33(66-39)27(51)21(50)11-41-34(56)18-6-8-19(40)9-7-18/h6-9,14,20-33,36-37,45,49-55H,10-13H2,1-5H3,(H,41,56)(H,42,46)(H,43,47)(H,44,48)(H,58,59)/p-1/t14-,20+,21-,22-,23-,24+,25-,26-,27-,28+,29+,30+,31-,32-,33-,36+,37+,39-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...				Bioorg Med Chem Lett 21: 5045-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.068 BindingDB Entry DOI: 10.7270/Q2WD40ZW
					More data for this Ligand-Target Pair
Myelin-associated glycoprotein (Homo sapiens (Human))	BDBM50354054 (CHEMBL1836334) Show SMILES COC(=O)[C@@H](NC(C)=O)[C@@H](C)O[C@H]1O[C@H](CO)[C@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O3)[C@H](O)[C@H](O)CNC(=O)c3ccccc3)C([O-])=O)[C@H]2O)[C@H]1NC(C)=O |r| Show InChI InChI=1S/C39H58N4O22/c1-15(24(35(56)59-5)41-16(2)46)60-36-26(43-18(4)48)31(28(52)22(13-44)61-36)63-37-30(54)33(29(53)23(14-45)62-37)65-39(38(57)58)11-20(49)25(42-17(3)47)32(64-39)27(51)21(50)12-40-34(55)19-9-7-6-8-10-19/h6-10,15,20-33,36-37,44-45,49-54H,11-14H2,1-5H3,(H,40,55)(H,41,46)(H,42,47)(H,43,48)(H,57,58)/p-1/t15-,20+,21-,22-,23-,24+,25-,26-,27-,28+,29+,30-,31-,32-,33+,36+,37+,39+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...				Bioorg Med Chem Lett 21: 5045-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.068 BindingDB Entry DOI: 10.7270/Q2WD40ZW
					More data for this Ligand-Target Pair
Myelin-associated glycoprotein (Homo sapiens (Human))	BDBM50354060 (CHEMBL1836339) Show SMILES COC(=O)[C@@H](NC(C)=O)[C@@H](C)O[C@H]1O[C@H](CO[C@@]2(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O2)[C@H](O)[C@H](O)CO)C([O-])=O)[C@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O3)[C@H](O)[C@H](O)CO)C([O-])=O)[C@H]2O)[C@H]1NC(C)=O |r| Show InChI InChI=1S/C43H70N4O30/c1-13(24(37(64)69-6)44-14(2)51)71-38-27(47-17(5)54)33(31(62)23(73-38)12-70-42(40(65)66)7-18(55)25(45-15(3)52)34(75-42)28(59)20(57)9-48)74-39-32(63)36(30(61)22(11-50)72-39)77-43(41(67)68)8-19(56)26(46-16(4)53)35(76-43)29(60)21(58)10-49/h13,18-36,38-39,48-50,55-63H,7-12H2,1-6H3,(H,44,51)(H,45,52)(H,46,53)(H,47,54)(H,65,66)(H,67,68)/p-2/t13-,18+,19+,20-,21-,22-,23-,24+,25-,26-,27-,28-,29-,30+,31+,32-,33-,34-,35-,36+,38+,39+,42-,43+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...				Bioorg Med Chem Lett 21: 5045-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.068 BindingDB Entry DOI: 10.7270/Q2WD40ZW
					More data for this Ligand-Target Pair
Myelin-associated glycoprotein (Homo sapiens (Human))	BDBM50354059 (CHEMBL1836338) Show SMILES COC(=O)[C@@H](NC(C)=O)[C@@H](C)O[C@H]1O[C@H](CO[C@@]2(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O2)[C@H](O)[C@H](O)CNC(=O)c2ccc(F)cc2)C([O-])=O)[C@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H]1NC(C)=O |r| Show InChI InChI=1S/C39H57FN4O22/c1-14(24(35(57)60-5)42-15(2)46)62-36-26(44-17(4)48)32(65-37-31(55)30(54)28(52)22(12-45)63-37)29(53)23(64-36)13-61-39(38(58)59)10-20(49)25(43-16(3)47)33(66-39)27(51)21(50)11-41-34(56)18-6-8-19(40)9-7-18/h6-9,14,20-33,36-37,45,49-55H,10-13H2,1-5H3,(H,41,56)(H,42,46)(H,43,47)(H,44,48)(H,58,59)/p-1/t14-,20+,21-,22-,23-,24+,25-,26-,27-,28+,29+,30+,31-,32-,33-,36+,37+,39-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...				Bioorg Med Chem Lett 21: 5045-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.068 BindingDB Entry DOI: 10.7270/Q2WD40ZW
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556745 (CHEMBL4753055) Show SMILES OC(=O)c1ccc(cc1)-c1cnc2n(Cc3ccccc3)cc(-c3ccc4nonc4c3)c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase C (Homo sapiens (Human))	BDBM50556732 (CHEMBL4750435) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3ccc(=O)oc3c2)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PTPRC (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP assa...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Myelin-associated glycoprotein (Homo sapiens (Human))	BDBM50354053 (CHEMBL1836313) Show SMILES COC(=O)[C@@H](NC(C)=O)[C@@H](C)O[C@H]1O[C@H](CO)[C@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O3)[C@H](O)[C@H](O)CO)C([O-])=O)[C@H]2O)[C@H]1NC(C)=O |r| Show InChI InChI=1S/C32H53N3O22/c1-10(18(28(48)51-5)33-11(2)39)52-29-20(35-13(4)41)25(22(45)16(8-37)53-29)55-30-24(47)27(23(46)17(9-38)54-30)57-32(31(49)50)6-14(42)19(34-12(3)40)26(56-32)21(44)15(43)7-36/h10,14-27,29-30,36-38,42-47H,6-9H2,1-5H3,(H,33,39)(H,34,40)(H,35,41)(H,49,50)/p-1/t10-,14+,15-,16-,17-,18+,19-,20-,21-,22+,23+,24-,25-,26-,27+,29+,30+,32+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...				Bioorg Med Chem Lett 21: 5045-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.068 BindingDB Entry DOI: 10.7270/Q2WD40ZW
					More data for this Ligand-Target Pair
Myelin-associated glycoprotein (Homo sapiens (Human))	BDBM50354050 (CHEMBL1836310) Show SMILES C[C@@H](O[C@H]1O[C@H](CO)[C@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O3)[C@H](O)[C@H](O)CO)C([O-])=O)[C@H]2O)[C@H]1NC(C)=O)[C@H](N)C(O)=O |r| Show InChI InChI=1S/C29H49N3O21/c1-8(15(30)25(44)45)48-26-17(32-10(3)37)22(19(41)13(6-34)49-26)51-27-21(43)24(20(42)14(7-35)50-27)53-29(28(46)47)4-11(38)16(31-9(2)36)23(52-29)18(40)12(39)5-33/h8,11-24,26-27,33-35,38-43H,4-7,30H2,1-3H3,(H,31,36)(H,32,37)(H,44,45)(H,46,47)/p-1/t8-,11+,12-,13-,14-,15+,16-,17-,18-,19+,20+,21-,22-,23-,24+,26+,27+,29+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAG				Bioorg Med Chem Lett 21: 5045-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.068 BindingDB Entry DOI: 10.7270/Q2WD40ZW
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556746 (CHEMBL4752755) Show SMILES COc1ccc(Cn2cc(-c3ccc4nonc4c3)c3cc(cnc23)-c2ccc(cc2)C(O)=O)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50556732 (CHEMBL4750435) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3ccc(=O)oc3c2)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PTPN2 (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP assa...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556738 (CHEMBL4743897) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc(cc2)C(F)(F)F)c2cc(cnc12)-c1cccc(c1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556752 (CHEMBL4760652) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3nonc3c2)c2cc(cnc12)C1=CCC(CC1)C(O)=O |t:31| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556740 (CHEMBL4776595) Show SMILES COc1ccc(cc1)-n1cc(-c2ccncc2)c2cc(cnc12)-c1cccc(c1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556742 (CHEMBL4788228) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3OCOc3c2)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50342004 (4-(2-(3-(4-nitrophenyl)-5-oxo-1-phenyl-1H-pyrazol-...) Show SMILES OS(=O)(=O)c1ccc(cc1)N=Nc1c([nH]n(-c2ccccc2)c1=O)-c1ccc(cc1)[N+]([O-])=O |w:10.10| Show InChI InChI=1S/C21H15N5O6S/c27-21-20(23-22-15-8-12-18(13-9-15)33(30,31)32)19(14-6-10-17(11-7-14)26(28)29)24-25(21)16-4-2-1-3-5-16/h1-13,24H,(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 20 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 22 (Homo sapiens (Human))	BDBM50556732 (CHEMBL4750435) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3ccc(=O)oc3c2)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DUSP22 (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556753 (CHEMBL4786030) Show SMILES CCOC(=O)c1ccc(cc1)-c1cnc2n(cc(-c3ccc4nonc4c3)c2c1)-c1ccc(OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556732 (CHEMBL4750435) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3ccc(=O)oc3c2)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 20 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50341989 (3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFUR...) Show SMILES CCc1oc2cc(ccc2c1C(=O)c1cc(Br)c(O)c(Br)c1)S(=O)(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C26H19Br2N3O7S3/c1-2-21-23(24(32)14-11-19(27)25(33)20(28)12-14)18-8-7-17(13-22(18)38-21)41(36,37)30-15-3-5-16(6-4-15)40(34,35)31-26-29-9-10-39-26/h3-13,30,33H,2H2,1H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556747 (CHEMBL4785204) Show SMILES COc1cccc(c1)-n1cc(-c2ccc3nonc3c2)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556751 (CHEMBL4786693) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3nonc3c2)c2cc(\C=C\C(O)=O)cnc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50342003 (CHEMBL501993 | NSC-87877 | disodium 8-hydroxy-7-[(...) Show SMILES Oc1c(cc(c2cccnc12)S([O-])(=O)=O)N=Nc1ccc2cc(ccc2c1)S([O-])(=O)=O |w:15.16| Show InChI InChI=1S/C19H13N3O7S2/c23-19-16(10-17(31(27,28)29)15-2-1-7-20-18(15)19)22-21-13-5-3-12-9-14(30(24,25)26)6-4-11(12)8-13/h1-10,23H,(H,24,25,26)(H,27,28,29)/p-2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 20 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556727 (CHEMBL4758364) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc(cc2)[N+]([O-])=O)c2cc(cnc12)-c1ccc(cc1)S(O)(=O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 20 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556726 (CHEMBL4754721) Show SMILES COc1ccc(cc1)-n1nc(-c2ccc(cc2)[N+]([O-])=O)c2cc(ccc12)-c1ccc(cc1)S(O)(=O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 20 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556750 (CHEMBL4750922) Show SMILES COc1ccc(cc1)-n1cc(-c2ccc3nonc3c2)c2cc(cnc12)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556744 (CHEMBL4762054) Show SMILES Cc1ccc(cc1)S(=O)(=O)n1cc(-c2ccc3nonc3c2)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50556739 (CHEMBL4750590) Show SMILES COc1ccc(cc1)-n1cc(-c2ccncc2)c2cc(cnc12)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01265 BindingDB Entry DOI: 10.7270/Q24171QP
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 112 total )  |  Next  |  Last  >>

Jump to: