Compile Data Set for Download or QSAR

Found 93 hits with Last Name = 'reidemeister' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM22541 (Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...) Show SMILES NC(SCCCc1cnc[nH]1)=NCc1ccc(Cl)cc1 |w:11.12| Show InChI InChI=1S/C14H17ClN4S/c15-12-5-3-11(4-6-12)8-18-14(16)20-7-1-2-13-9-17-10-19-13/h3-6,9-10H,1-2,7-8H2,(H2,16,18)(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM22914 (CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...) Show SMILES S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1 Show InChI InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074066 (CHEMBL154478 | Heptyl-carbamic acid 3-(1H-imidazol...) Show SMILES CCCCCCCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C14H25N3O2/c1-2-3-4-5-6-9-16-14(18)19-10-7-8-13-11-15-12-17-13/h11-12H,2-10H2,1H3,(H,15,17)(H,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074076 ((3-Methyl-pentyl)-carbamic acid 3-(1H-imidazol-4-y...) Show SMILES CCC(C)CCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C13H23N3O2/c1-3-11(2)6-7-15-13(17)18-8-4-5-12-9-14-10-16-12/h9-11H,3-8H2,1-2H3,(H,14,16)(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074061 (CHEMBL346573 | Octyl-carbamic acid 3-(1H-imidazol-...) Show SMILES CCCCCCCCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C15H27N3O2/c1-2-3-4-5-6-7-10-17-15(19)20-11-8-9-14-12-16-13-18-14/h12-13H,2-11H2,1H3,(H,16,18)(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074082 ((3-Methyl-butyl)-carbamic acid 3-(1H-imidazol-4-yl...) Show SMILES CC(C)CCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C12H21N3O2/c1-10(2)5-6-14-12(16)17-7-3-4-11-8-13-9-15-11/h8-10H,3-7H2,1-2H3,(H,13,15)(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074085 (CHEMBL154977 | Pentyl-carbamic acid 3-(1H-imidazol...) Show SMILES CCCCCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C12H21N3O2/c1-2-3-4-7-14-12(16)17-8-5-6-11-9-13-10-15-11/h9-10H,2-8H2,1H3,(H,13,15)(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074070 (CHEMBL156413 | Hexyl-carbamic acid 3-(1H-imidazol-...) Show SMILES CCCCCCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C13H23N3O2/c1-2-3-4-5-8-15-13(17)18-9-6-7-12-10-14-11-16-12/h10-11H,2-9H2,1H3,(H,14,16)(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074072 ((1-Methyl-pentyl)-carbamic acid 3-(1H-imidazol-4-y...) Show SMILES CCCCC(C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C13H23N3O2/c1-3-4-6-11(2)16-13(17)18-8-5-7-12-9-14-10-15-12/h9-11H,3-8H2,1-2H3,(H,14,15)(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50408755 (CHEMBL2145442) Show SMILES CC(C)CCCOCCCc1cnc[nH]1 Show InChI InChI=1S/C12H22N2O/c1-11(2)5-3-7-15-8-4-6-12-9-13-10-14-12/h9-11H,3-8H2,1-2H3,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro binding affinity against histamine H3 receptor from synaptosomes of rat cerebral cortex				J Med Chem 42: 4269-74 (1999) BindingDB Entry DOI: 10.7270/Q2B85799
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50118156 (4-[3-(3,3-Dimethyl-butoxy)-propyl]-1H-imidazole | ...) Show SMILES CC(C)(C)CCOCCCc1cnc[nH]1 Show InChI InChI=1S/C12H22N2O/c1-12(2,3)6-8-15-7-4-5-11-9-13-10-14-11/h9-10H,4-8H2,1-3H3,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro binding affinity against histamine H3 receptor from synaptosomes of rat cerebral cortex				J Med Chem 42: 4269-74 (1999) BindingDB Entry DOI: 10.7270/Q2B85799
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074063 (((S)-1-Methyl-pentyl)-carbamic acid 3-(1H-imidazol...) Show SMILES CCCC[C@H](C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C13H23N3O2/c1-3-4-6-11(2)16-13(17)18-8-5-7-12-9-14-10-15-12/h9-11H,3-8H2,1-2H3,(H,14,15)(H,16,17)/t11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074083 (((R)-1-Methyl-butyl)-carbamic acid 3-(1H-imidazol-...) Show SMILES CCC[C@@H](C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C12H21N3O2/c1-3-5-10(2)15-12(16)17-7-4-6-11-8-13-9-14-11/h8-10H,3-7H2,1-2H3,(H,13,14)(H,15,16)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50408756 (CHEMBL2145444) Show SMILES CC(C)CCOCCCc1cnc[nH]1 Show InChI InChI=1S/C11H20N2O/c1-10(2)5-7-14-6-3-4-11-8-12-9-13-11/h8-10H,3-7H2,1-2H3,(H,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro binding affinity against histamine H3 receptor from synaptosomes of rat cerebral cortex				J Med Chem 42: 4269-74 (1999) BindingDB Entry DOI: 10.7270/Q2B85799
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074064 ((2-Methyl-butyl)-carbamic acid 3-(1H-imidazol-4-yl...) Show SMILES CCC(C)CNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C12H21N3O2/c1-3-10(2)7-14-12(16)17-6-4-5-11-8-13-9-15-11/h8-10H,3-7H2,1-2H3,(H,13,15)(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074088 ((2-Methyl-pentyl)-carbamic acid 3-(1H-imidazol-4-y...) Show SMILES CCCC(C)CNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C13H23N3O2/c1-3-5-11(2)8-15-13(17)18-7-4-6-12-9-14-10-16-12/h9-11H,3-8H2,1-2H3,(H,14,16)(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074067 (Butyl-carbamic acid 3-(1H-imidazol-4-yl)-propyl es...) Show SMILES CCCCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C11H19N3O2/c1-2-3-6-13-11(15)16-7-4-5-10-8-12-9-14-10/h8-9H,2-7H2,1H3,(H,12,14)(H,13,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074086 (((S)-1-Methyl-hexyl)-carbamic acid 3-(1H-imidazol-...) Show SMILES CCCCC[C@H](C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C14H25N3O2/c1-3-4-5-7-12(2)17-14(18)19-9-6-8-13-10-15-11-16-13/h10-12H,3-9H2,1-2H3,(H,15,16)(H,17,18)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074069 ((1-Methyl-heptyl)-carbamic acid 3-(1H-imidazol-4-y...) Show SMILES CCCCCCC(C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C15H27N3O2/c1-3-4-5-6-8-13(2)18-15(19)20-10-7-9-14-11-16-12-17-14/h11-13H,3-10H2,1-2H3,(H,16,17)(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074073 ((1-Methyl-hexyl)-carbamic acid 3-(1H-imidazol-4-yl...) Show SMILES CCCCCC(C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C14H25N3O2/c1-3-4-5-7-12(2)17-14(18)19-9-6-8-13-10-15-11-16-13/h10-12H,3-9H2,1-2H3,(H,15,16)(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074068 (((S)-2-Methyl-butyl)-carbamic acid 3-(1H-imidazol-...) Show SMILES CC[C@H](C)CNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C12H21N3O2/c1-3-10(2)7-14-12(16)17-6-4-5-11-8-13-9-15-11/h8-10H,3-7H2,1-2H3,(H,13,15)(H,14,16)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074080 (((R)-1-Methyl-pentyl)-carbamic acid 3-(1H-imidazol...) Show SMILES CCCC[C@@H](C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C13H23N3O2/c1-3-4-6-11(2)16-13(17)18-8-5-7-12-9-14-10-15-12/h9-11H,3-8H2,1-2H3,(H,14,15)(H,16,17)/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074071 (((R)-sec-Butyl)-carbamic acid 3-(1H-imidazol-4-yl)...) Show SMILES CC[C@@H](C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C11H19N3O2/c1-3-9(2)14-11(15)16-6-4-5-10-7-12-8-13-10/h7-9H,3-6H2,1-2H3,(H,12,13)(H,14,15)/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074087 (CHEMBL1076266 | CHEMBL157493 | sec-Butyl-carbamic ...) Show SMILES CCC(C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C11H19N3O2/c1-3-9(2)14-11(15)16-6-4-5-10-7-12-8-13-10/h7-9H,3-6H2,1-2H3,(H,12,13)(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074075 ((3-Methylsulfanyl-propyl)-carbamic acid 3-(1H-imid...) Show SMILES CSCCCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C11H19N3O2S/c1-17-7-3-5-13-11(15)16-6-2-4-10-8-12-9-14-10/h8-9H,2-7H2,1H3,(H,12,14)(H,13,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50081713 ((2,2-Dimethyl-propyl)-carbamic acid 3-(1H-imidazol...) Show SMILES CC(C)(C)CNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C12H21N3O2/c1-12(2,3)8-14-11(16)17-6-4-5-10-7-13-9-15-10/h7,9H,4-6,8H2,1-3H3,(H,13,15)(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro binding affinity against histamine H3 receptor from synaptosomes of rat cerebral cortex				J Med Chem 42: 4269-74 (1999) BindingDB Entry DOI: 10.7270/Q2B85799
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074077 (((S)-sec-Butyl)-carbamic acid 3-(1H-imidazol-4-yl)...) Show SMILES CC[C@H](C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C11H19N3O2/c1-3-9(2)14-11(15)16-6-4-5-10-7-12-8-13-10/h7-9H,3-6H2,1-2H3,(H,12,13)(H,14,15)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074065 (((R)-1-Methyl-hexyl)-carbamic acid 3-(1H-imidazol-...) Show SMILES CCCCC[C@@H](C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C14H25N3O2/c1-3-4-5-7-12(2)17-14(18)19-9-6-8-13-10-15-11-16-13/h10-12H,3-9H2,1-2H3,(H,15,16)(H,17,18)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074062 ((1-Methyl-butyl)-carbamic acid 3-(1H-imidazol-4-yl...) Show SMILES CCCC(C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C12H21N3O2/c1-3-5-10(2)15-12(16)17-7-4-6-11-8-13-9-14-11/h8-10H,3-7H2,1-2H3,(H,13,14)(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074074 (CHEMBL155258 | CHEMBL2145440 | Isobutyl-carbamic a...) Show SMILES CC(C)CNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C11H19N3O2/c1-9(2)6-13-11(15)16-5-3-4-10-7-12-8-14-10/h7-9H,3-6H2,1-2H3,(H,12,14)(H,13,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro binding affinity against histamine H3 receptor from synaptosomes of rat cerebral cortex				J Med Chem 42: 4269-74 (1999) BindingDB Entry DOI: 10.7270/Q2B85799
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074074 (CHEMBL155258 | CHEMBL2145440 | Isobutyl-carbamic a...) Show SMILES CC(C)CNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C11H19N3O2/c1-9(2)6-13-11(15)16-5-3-4-10-7-12-8-14-10/h7-9H,3-6H2,1-2H3,(H,12,14)(H,13,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50081714 ((1,1,3,3-Tetramethyl-butyl)-carbamic acid 3-(1H-im...) Show SMILES CC(C)(C)CC(C)(C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C15H27N3O2/c1-14(2,3)10-15(4,5)18-13(19)20-8-6-7-12-9-16-11-17-12/h9,11H,6-8,10H2,1-5H3,(H,16,17)(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro binding affinity against histamine H3 receptor from synaptosomes of rat cerebral cortex				J Med Chem 42: 4269-74 (1999) BindingDB Entry DOI: 10.7270/Q2B85799
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074078 (CHEMBL345808 | Propyl-carbamic acid 3-(1H-imidazol...) Show SMILES CCCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C10H17N3O2/c1-2-5-12-10(14)15-6-3-4-9-7-11-8-13-9/h7-8H,2-6H2,1H3,(H,11,13)(H,12,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074079 (CHEMBL350456 | CHEMBL422809 | Isopropyl-carbamic a...) Show SMILES CC(C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C10H17N3O2/c1-8(2)13-10(14)15-5-3-4-9-6-11-7-12-9/h6-8H,3-5H2,1-2H3,(H,11,12)(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro binding affinity against histamine H3 receptor from synaptosomes of rat cerebral cortex				J Med Chem 42: 4269-74 (1999) BindingDB Entry DOI: 10.7270/Q2B85799
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074079 (CHEMBL350456 | CHEMBL422809 | Isopropyl-carbamic a...) Show SMILES CC(C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C10H17N3O2/c1-8(2)13-10(14)15-5-3-4-9-6-11-7-12-9/h6-8H,3-5H2,1-2H3,(H,11,12)(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50408754 (CHEMBL2145441) Show SMILES CC(C)COCCCc1cnc[nH]1 Show InChI InChI=1S/C10H18N2O/c1-9(2)7-13-5-3-4-10-6-11-8-12-10/h6,8-9H,3-5,7H2,1-2H3,(H,11,12)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	139	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro binding affinity against histamine H3 receptor from synaptosomes of rat cerebral cortex				J Med Chem 42: 4269-74 (1999) BindingDB Entry DOI: 10.7270/Q2B85799
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074081 ((3-Methoxy-propyl)-carbamic acid 3-(1H-imidazol-4-...) Show SMILES COCCCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C11H19N3O3/c1-16-6-3-5-13-11(15)17-7-2-4-10-8-12-9-14-10/h8-9H,2-7H2,1H3,(H,12,14)(H,13,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	155	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074084 (CHEMBL157893 | Ethyl-carbamic acid 3-(1H-imidazol-...) Show SMILES CCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C9H15N3O2/c1-2-11-9(13)14-5-3-4-8-6-10-7-12-8/h6-7H,2-5H2,1H3,(H,10,12)(H,11,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50308093 (1-[3-(2-Hydroxy-ethoxy)-benzyl]-4-(4-isopropyl-phe...) Show SMILES CC(C)c1ccc(cc1)-c1nc(=S)n(Cc2cccc(OCCO)c2)c2ccc(OCC#C)cc12 Show InChI InChI=1S/C29H28N2O3S/c1-4-15-33-25-12-13-27-26(18-25)28(23-10-8-22(9-11-23)20(2)3)30-29(35)31(27)19-21-6-5-7-24(17-21)34-16-14-32/h1,5-13,17-18,20,32H,14-16,19H2,2-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...				J Med Chem 53: 2250-63 (2010) Article DOI: 10.1021/jm901811v BindingDB Entry DOI: 10.7270/Q2Q240BT
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50308090 (1-(3-Ethoxy-4-methoxy-benzyl)-4-(4-isopropyl-pheny...) Show SMILES CCOc1cc(Cn2c3ccc(OCC#C)cc3c(nc2=O)-c2ccc(cc2)C(C)C)ccc1OC Show InChI InChI=1S/C30H30N2O4/c1-6-16-36-24-13-14-26-25(18-24)29(23-11-9-22(10-12-23)20(3)4)31-30(33)32(26)19-21-8-15-27(34-5)28(17-21)35-7-2/h1,8-15,17-18,20H,7,16,19H2,2-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...				J Med Chem 53: 2250-63 (2010) Article DOI: 10.1021/jm901811v BindingDB Entry DOI: 10.7270/Q2Q240BT
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50308081 (4-(4-Isopropyl-phenyl)-1-(4-methyl-benzyl)-6-propa...) Show SMILES CC(C)c1ccc(cc1)-c1nc(=O)n(Cc2ccc(C)cc2)c2ccc(OCC#C)cc12 Show InChI InChI=1S/C28H26N2O2/c1-5-16-32-24-14-15-26-25(17-24)27(23-12-10-22(11-13-23)19(2)3)29-28(31)30(26)18-21-8-6-20(4)7-9-21/h1,6-15,17,19H,16,18H2,2-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...				J Med Chem 53: 2250-63 (2010) Article DOI: 10.1021/jm901811v BindingDB Entry DOI: 10.7270/Q2Q240BT
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50308087 (4-(4-Isopropyl-phenyl)-1-(3-methyl-benzyl)-6-propa...) Show SMILES CC(C)c1ccc(cc1)-c1nc(=O)n(Cc2cccc(C)c2)c2ccc(OCC#C)cc12 Show InChI InChI=1S/C28H26N2O2/c1-5-15-32-24-13-14-26-25(17-24)27(23-11-9-22(10-12-23)19(2)3)29-28(31)30(26)18-21-8-6-7-20(4)16-21/h1,6-14,16-17,19H,15,18H2,2-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...				J Med Chem 53: 2250-63 (2010) Article DOI: 10.1021/jm901811v BindingDB Entry DOI: 10.7270/Q2Q240BT
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50308103 (CHEMBL590539 | N-{3-[4-(4-Isopropyl-pheny)-2-oxo-6...) Show SMILES CC(C)c1ccc(cc1)-c1nc(=O)n(Cc2cccc(NC(=O)CN3CCN(C)CC3)c2)c2ccc(OCC#C)cc12 Show InChI InChI=1S/C34H37N5O3/c1-5-19-42-29-13-14-31-30(21-29)33(27-11-9-26(10-12-27)24(2)3)36-34(41)39(31)22-25-7-6-8-28(20-25)35-32(40)23-38-17-15-37(4)16-18-38/h1,6-14,20-21,24H,15-19,22-23H2,2-4H3,(H,35,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...				J Med Chem 53: 2250-63 (2010) Article DOI: 10.1021/jm901811v BindingDB Entry DOI: 10.7270/Q2Q240BT
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50308108 (1-Benzyl-5-cyclopropylmethyl-6-hydroxy-4-(4-isopro...) Show SMILES CC(C)c1ccc(cc1)-c1nc(=O)n(Cc2ccccc2)c2ccc(O)c(CC3CC3)c12 Show InChI InChI=1S/C28H28N2O2/c1-18(2)21-10-12-22(13-11-21)27-26-23(16-19-8-9-19)25(31)15-14-24(26)30(28(32)29-27)17-20-6-4-3-5-7-20/h3-7,10-15,18-19,31H,8-9,16-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...				J Med Chem 53: 2250-63 (2010) Article DOI: 10.1021/jm901811v BindingDB Entry DOI: 10.7270/Q2Q240BT
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50308089 (1-(3-Methoxy-benzyl)-4-(4-isopropyl-phenyl)-6-prop...) Show SMILES COc1cccc(Cn2c3ccc(OCC#C)cc3c(nc2=O)-c2ccc(cc2)C(C)C)c1 Show InChI InChI=1S/C28H26N2O3/c1-5-15-33-24-13-14-26-25(17-24)27(22-11-9-21(10-12-22)19(2)3)29-28(31)30(26)18-20-7-6-8-23(16-20)32-4/h1,6-14,16-17,19H,15,18H2,2-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...				J Med Chem 53: 2250-63 (2010) Article DOI: 10.1021/jm901811v BindingDB Entry DOI: 10.7270/Q2Q240BT
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50308091 (CHEMBL597194 | {3-[4-(4-Isopropyl-phenyl)-2-oxo-6-...) Show SMILES CC(C)c1ccc(cc1)-c1nc(=O)n(Cc2cccc(OCC(O)=O)c2)c2ccc(OCC#C)cc12 Show InChI InChI=1S/C29H26N2O5/c1-4-14-35-24-12-13-26-25(16-24)28(22-10-8-21(9-11-22)19(2)3)30-29(34)31(26)17-20-6-5-7-23(15-20)36-18-27(32)33/h1,5-13,15-16,19H,14,17-18H2,2-3H3,(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...				J Med Chem 53: 2250-63 (2010) Article DOI: 10.1021/jm901811v BindingDB Entry DOI: 10.7270/Q2Q240BT
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50308106 (5-Allyl-1-benzyl-6-hydroxy-4-(4-isopropyl-phenyl)-...) Show SMILES CC(C)c1ccc(cc1)-c1nc(=O)n(Cc2ccccc2)c2ccc(O)c(CC=C)c12 Show InChI InChI=1S/C27H26N2O2/c1-4-8-22-24(30)16-15-23-25(22)26(21-13-11-20(12-14-21)18(2)3)28-27(31)29(23)17-19-9-6-5-7-10-19/h4-7,9-16,18,30H,1,8,17H2,2-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...				J Med Chem 53: 2250-63 (2010) Article DOI: 10.1021/jm901811v BindingDB Entry DOI: 10.7270/Q2Q240BT
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50308084 (4-(4-Isopropyl-phenyl)-1-(4-methoxy-benzyl)-6-prop...) Show SMILES COc1ccc(Cn2c3ccc(OCC#C)cc3c(nc2=O)-c2ccc(cc2)C(C)C)cc1 Show InChI InChI=1S/C28H26N2O3/c1-5-16-33-24-14-15-26-25(17-24)27(22-10-8-21(9-11-22)19(2)3)29-28(31)30(26)18-20-6-12-23(32-4)13-7-20/h1,6-15,17,19H,16,18H2,2-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...				J Med Chem 53: 2250-63 (2010) Article DOI: 10.1021/jm901811v BindingDB Entry DOI: 10.7270/Q2Q240BT
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50308082 (1-(4-Ethyl-benzyl)-4-(4-isopropyl-phenyl)-6-propar...) Show SMILES CCc1ccc(Cn2c3ccc(OCC#C)cc3c(nc2=O)-c2ccc(cc2)C(C)C)cc1 Show InChI InChI=1S/C29H28N2O2/c1-5-17-33-25-15-16-27-26(18-25)28(24-13-11-23(12-14-24)20(3)4)30-29(32)31(27)19-22-9-7-21(6-2)8-10-22/h1,7-16,18,20H,6,17,19H2,2-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...				J Med Chem 53: 2250-63 (2010) Article DOI: 10.1021/jm901811v BindingDB Entry DOI: 10.7270/Q2Q240BT
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50308080 (1-Benzyl-4-(4-isopropyl-phenyl)-6-propargyloxy-1H-...) Show SMILES CC(C)c1ccc(cc1)-c1nc(=O)n(Cc2ccccc2)c2ccc(OCC#C)cc12 Show InChI InChI=1S/C27H24N2O2/c1-4-16-31-23-14-15-25-24(17-23)26(22-12-10-21(11-13-22)19(2)3)28-27(30)29(25)18-20-8-6-5-7-9-20/h1,5-15,17,19H,16,18H2,2-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...				J Med Chem 53: 2250-63 (2010) Article DOI: 10.1021/jm901811v BindingDB Entry DOI: 10.7270/Q2Q240BT
					More data for this Ligand-Target Pair

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