Compile Data Set for Download or QSAR

Found 32 hits with Last Name = 'reisch' and Initial = 'ha'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50354578 (BUPRENORPHINE | US10752592, Compound buprenorphine...) Show SMILES CO[C@@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |r| Show InChI InChI=1S/C29H41NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3/t20-,21-,24-,26+,27-,28+,29+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	US Patent	0.0400	-59.3	n/a	n/a	n/a	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM222959 (US9315514, 3) Show SMILES CC(C)(C)[C@@]1(C)OCO[C@]23CC[C@@]4(C[C@H]12)[C@H]1Cc2ccc(O)c5O[C@@H]3[C@]4(CCN1CC1CC1)c25 |r,TLB:4:14:25.24:11.10| Show InChI InChI=1S/C29H39NO4/c1-25(2,3)26(4)20-14-27-9-10-29(20,33-16-32-26)24-28(27)11-12-30(15-17-5-6-17)21(27)13-18-7-8-19(31)23(34-24)22(18)28/h7-8,17,20-21,24,31H,5-6,9-16H2,1-4H3/t20-,21-,24-,26+,27-,28+,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.120	-56.6	n/a	n/a	n/a	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM222960 (US9315514, 4) Show SMILES CCC1O[C@@](C)([C@H]2C[C@]34CC[C@]2(O1)[C@@H]1Oc2c5c(C[C@H]3N(CC3CC3)CC[C@@]415)ccc2O)C(C)(C)C |r,TLB:4:6:27.13:9.10| Show InChI InChI=1S/C31H43NO4/c1-6-23-35-28(5,27(2,3)4)21-16-29-11-12-31(21,36-23)26-30(29)13-14-32(17-18-7-8-18)22(29)15-19-9-10-20(33)25(34-26)24(19)30/h9-10,18,21-23,26,33H,6-8,11-17H2,1-5H3/t21-,22-,23?,26-,28+,29-,30+,31-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.190	-55.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50354578 (BUPRENORPHINE | US10752592, Compound buprenorphine...) Show SMILES CO[C@@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |r| Show InChI InChI=1S/C29H41NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3/t20-,21-,24-,26+,27-,28+,29+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	US Patent	0.300	-58.9	n/a	n/a	n/a	n/a	n/a	7.4	50
Rhodes Technologies US Patent					Assay Description Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membr...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM222960 (US9315514, 4) Show SMILES CCC1O[C@@](C)([C@H]2C[C@]34CC[C@]2(O1)[C@@H]1Oc2c5c(C[C@H]3N(CC3CC3)CC[C@@]415)ccc2O)C(C)(C)C |r,TLB:4:6:27.13:9.10| Show InChI InChI=1S/C31H43NO4/c1-6-23-35-28(5,27(2,3)4)21-16-29-11-12-31(21,36-23)26-30(29)13-14-32(17-18-7-8-18)22(29)15-19-9-10-20(33)25(34-26)24(19)30/h9-10,18,21-23,26,33H,6-8,11-17H2,1-5H3/t21-,22-,23?,26-,28+,29-,30+,31-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.350	-58.5	n/a	n/a	n/a	n/a	n/a	7.4	50
Rhodes Technologies US Patent					Assay Description Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membr...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM222963 (US9315514, 11) Show SMILES CC(C)(C)[C@@]1(C)OCO[C@]23C=C[C@@]4(C[C@H]12)[C@H]1Cc2ccc(O)c5O[C@@H]3[C@]4(CCN1CC1CC1)c25 |r,c:10,TLB:4:14:25.24:11.10| Show InChI InChI=1S/C29H37NO4/c1-25(2,3)26(4)20-14-27-9-10-29(20,33-16-32-26)24-28(27)11-12-30(15-17-5-6-17)21(27)13-18-7-8-19(31)23(34-24)22(18)28/h7-10,17,20-21,24,31H,5-6,11-16H2,1-4H3/t20-,21-,24-,26+,27-,28+,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.440	-53.4	n/a	n/a	n/a	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM222959 (US9315514, 3) Show SMILES CC(C)(C)[C@@]1(C)OCO[C@]23CC[C@@]4(C[C@H]12)[C@H]1Cc2ccc(O)c5O[C@@H]3[C@]4(CCN1CC1CC1)c25 |r,TLB:4:14:25.24:11.10| Show InChI InChI=1S/C29H39NO4/c1-25(2,3)26(4)20-14-27-9-10-29(20,33-16-32-26)24-28(27)11-12-30(15-17-5-6-17)21(27)13-18-7-8-19(31)23(34-24)22(18)28/h7-8,17,20-21,24,31H,5-6,9-16H2,1-4H3/t20-,21-,24-,26+,27-,28+,29-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.450	-57.8	n/a	n/a	n/a	n/a	n/a	7.4	50
Rhodes Technologies US Patent					Assay Description Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membr...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM222961 (US9315514, 5) Show SMILES CCCC1O[C@@](C)([C@H]2C[C@]34CC[C@]2(O1)[C@@H]1Oc2c5c(C[C@H]3N(CC3CC3)CC[C@@]415)ccc2O)C(C)(C)C |r,TLB:5:7:28.14:10.11| Show InChI InChI=1S/C32H45NO4/c1-6-7-24-36-29(5,28(2,3)4)22-17-30-12-13-32(22,37-24)27-31(30)14-15-33(18-19-8-9-19)23(30)16-20-10-11-21(34)26(35-27)25(20)31/h10-11,19,22-24,27,34H,6-9,12-18H2,1-5H3/t22-,23-,24?,27-,29+,30-,31+,32-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.540	-57.3	n/a	n/a	n/a	n/a	n/a	7.4	50
Rhodes Technologies US Patent					Assay Description Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membr...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM222961 (US9315514, 5) Show SMILES CCCC1O[C@@](C)([C@H]2C[C@]34CC[C@]2(O1)[C@@H]1Oc2c5c(C[C@H]3N(CC3CC3)CC[C@@]415)ccc2O)C(C)(C)C |r,TLB:5:7:28.14:10.11| Show InChI InChI=1S/C32H45NO4/c1-6-7-24-36-29(5,28(2,3)4)22-17-30-12-13-32(22,37-24)27-31(30)14-15-33(18-19-8-9-19)23(30)16-20-10-11-21(34)26(35-27)25(20)31/h10-11,19,22-24,27,34H,6-9,12-18H2,1-5H3/t22-,23-,24?,27-,29+,30-,31+,32-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.720	-52.2	n/a	n/a	n/a	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM222962 (US9315514, 6) Show SMILES CC(C)(C)[C@@]1(C)OC(O[C@]23CC[C@@]4(C[C@H]12)[C@H]1Cc2ccc(O)c5O[C@@H]3[C@]4(CCN1CC1CC1)c25)c1ccccc1 |r,TLB:4:14:25.24:11.10| Show InChI InChI=1S/C35H43NO4/c1-31(2,3)32(4)25-19-33-14-15-35(25,40-29(39-32)22-8-6-5-7-9-22)30-34(33)16-17-36(20-21-10-11-21)26(33)18-23-12-13-24(37)28(38-30)27(23)34/h5-9,12-13,21,25-26,29-30,37H,10-11,14-20H2,1-4H3/t25-,26-,29?,30-,32+,33-,34+,35-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.26	-53.5	n/a	n/a	n/a	n/a	n/a	7.4	50
Rhodes Technologies US Patent					Assay Description Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membr...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM222962 (US9315514, 6) Show SMILES CC(C)(C)[C@@]1(C)OC(O[C@]23CC[C@@]4(C[C@H]12)[C@H]1Cc2ccc(O)c5O[C@@H]3[C@]4(CCN1CC1CC1)c25)c1ccccc1 |r,TLB:4:14:25.24:11.10| Show InChI InChI=1S/C35H43NO4/c1-31(2,3)32(4)25-19-33-14-15-35(25,40-29(39-32)22-8-6-5-7-9-22)30-34(33)16-17-36(20-21-10-11-21)26(33)18-23-12-13-24(37)28(38-30)27(23)34/h5-9,12-13,21,25-26,29-30,37H,10-11,14-20H2,1-4H3/t25-,26-,29?,30-,32+,33-,34+,35-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.61	-47.6	n/a	n/a	n/a	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM222965 (US9315514, 8) Show SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@]12CC[C@@]35C[C@@H]1[C@](C)(OCO2)C(C)(C)C |r,THB:26:25:15.16:22.21| Show InChI InChI=1S/C30H41NO4/c1-26(2,3)27(4)21-15-28-10-11-30(21,34-17-33-27)25-29(28)12-13-31(16-18-6-7-18)22(28)14-19-8-9-20(32-5)24(35-25)23(19)29/h8-9,18,21-22,25H,6-7,10-17H2,1-5H3/t21-,22-,25-,27+,28-,29+,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.22	-46.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM222964 (US9315514, 12) Show SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@]12OCO[C@@](C)([C@H]1C[C@]35C=C2)C(C)(C)C |r,wU:15.22,26.31,16.17,20.24,24.28,wD:28.32,7.7,24.38,c:36,THB:24:26:15.16:29.30,(-5.66,6.41,;-4.41,5.57,;-4.51,4.07,;-5.84,3.3,;-5.78,1.78,;-4.58,.83,;-4.24,-.67,;-2.82,-1.39,;-3.66,-2.77,;-4.98,-3.5,;-5,-5.01,;-4.27,-6.32,;-5.78,-6.3,;-2.13,-2.79,;-1.89,-1.21,;-1.87,.53,;-.88,2.03,;-1.72,3.37,;-3.26,3.12,;-3.19,1.53,;.82,2.54,;1.44,3.95,;2.97,3.84,;3.61,2.41,;3.17,.89,;2.96,-.6,;1.59,1,;.76,-.5,;-1,-.87,;-.25,.18,;.23,1.41,;4.64,.58,;6.11,.26,;4.95,2.05,;4.32,-.89,)| Show InChI InChI=1S/C30H39NO4/c1-26(2,3)27(4)21-15-28-10-11-30(21,34-17-33-27)25-29(28)12-13-31(16-18-6-7-18)22(28)14-19-8-9-20(32-5)24(35-25)23(19)29/h8-11,18,21-22,25H,6-7,12-17H2,1-5H3/t21-,22-,25-,27+,28-,29+,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	30.1	-42.9	n/a	n/a	n/a	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM222966 (US9315514, 7) Show SMILES CC(C)(C)[C@@]1(C)OCO[C@]23CC[C@@]4(C[C@H]12)[C@H]1Cc2ccc(OCc5ccccc5)c5O[C@@H]3[C@]4(CCN1CC1CC1)c25 |r,TLB:4:14:32.31:11.10| Show InChI InChI=1S/C36H45NO4/c1-32(2,3)33(4)27-19-34-14-15-36(27,40-22-39-33)31-35(34)16-17-37(20-23-10-11-23)28(34)18-25-12-13-26(30(41-31)29(25)35)38-21-24-8-6-5-7-9-24/h5-9,12-13,23,27-28,31H,10-11,14-22H2,1-4H3/t27-,28-,31-,33+,34-,35+,36-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	757	-34.9	n/a	n/a	n/a	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50354578 (BUPRENORPHINE | US10752592, Compound buprenorphine...) Show SMILES CO[C@@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |r| Show InChI InChI=1S/C29H41NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3/t20-,21-,24-,26+,27-,28+,29+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	0.450	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description [35S]GTPγS functional assays were conducted using freshly thawed μ-receptor membranes prepared in-house from a cell line expressing recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM222966 (US9315514, 7) Show SMILES CC(C)(C)[C@@]1(C)OCO[C@]23CC[C@@]4(C[C@H]12)[C@H]1Cc2ccc(OCc5ccccc5)c5O[C@@H]3[C@]4(CCN1CC1CC1)c25 |r,TLB:4:14:32.31:11.10| Show InChI InChI=1S/C36H45NO4/c1-32(2,3)33(4)27-19-34-14-15-36(27,40-22-39-33)31-35(34)16-17-37(20-23-10-11-23)28(34)18-25-12-13-26(30(41-31)29(25)35)38-21-24-8-6-5-7-9-24/h5-9,12-13,23,27-28,31H,10-11,14-22H2,1-4H3/t27-,28-,31-,33+,34-,35+,36-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Functional [35S]GTPγS binding assays were conducted as follows. κ opioid receptor membrane solution was prepared by sequentially adding f...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50354578 (BUPRENORPHINE | US10752592, Compound buprenorphine...) Show SMILES CO[C@@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |r| Show InChI InChI=1S/C29H41NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3/t20-,21-,24-,26+,27-,28+,29+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	0.560	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Functional [35S]GTPγS binding assays were conducted as follows. κ opioid receptor membrane solution was prepared by sequentially adding f...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM222959 (US9315514, 3) Show SMILES CC(C)(C)[C@@]1(C)OCO[C@]23CC[C@@]4(C[C@H]12)[C@H]1Cc2ccc(O)c5O[C@@H]3[C@]4(CCN1CC1CC1)c25 |r,TLB:4:14:25.24:11.10| Show InChI InChI=1S/C29H39NO4/c1-25(2,3)26(4)20-14-27-9-10-29(20,33-16-32-26)24-28(27)11-12-30(15-17-5-6-17)21(27)13-18-7-8-19(31)23(34-24)22(18)28/h7-8,17,20-21,24,31H,5-6,9-16H2,1-4H3/t20-,21-,24-,26+,27-,28+,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	22.7	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Functional [35S]GTPγS binding assays were conducted as follows. κ opioid receptor membrane solution was prepared by sequentially adding f...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM222960 (US9315514, 4) Show SMILES CCC1O[C@@](C)([C@H]2C[C@]34CC[C@]2(O1)[C@@H]1Oc2c5c(C[C@H]3N(CC3CC3)CC[C@@]415)ccc2O)C(C)(C)C |r,TLB:4:6:27.13:9.10| Show InChI InChI=1S/C31H43NO4/c1-6-23-35-28(5,27(2,3)4)21-16-29-11-12-31(21,36-23)26-30(29)13-14-32(17-18-7-8-18)22(29)15-19-9-10-20(33)25(34-26)24(19)30/h9-10,18,21-23,26,33H,6-8,11-17H2,1-5H3/t21-,22-,23?,26-,28+,29-,30+,31-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.42	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Functional [35S]GTPγS binding assays were conducted as follows. κ opioid receptor membrane solution was prepared by sequentially adding f...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM222961 (US9315514, 5) Show SMILES CCCC1O[C@@](C)([C@H]2C[C@]34CC[C@]2(O1)[C@@H]1Oc2c5c(C[C@H]3N(CC3CC3)CC[C@@]415)ccc2O)C(C)(C)C |r,TLB:5:7:28.14:10.11| Show InChI InChI=1S/C32H45NO4/c1-6-7-24-36-29(5,28(2,3)4)22-17-30-12-13-32(22,37-24)27-31(30)14-15-33(18-19-8-9-19)23(30)16-20-10-11-21(34)26(35-27)25(20)31/h10-11,19,22-24,27,34H,6-9,12-18H2,1-5H3/t22-,23-,24?,27-,29+,30-,31+,32-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.48	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Functional [35S]GTPγS binding assays were conducted as follows. κ opioid receptor membrane solution was prepared by sequentially adding f...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM222962 (US9315514, 6) Show SMILES CC(C)(C)[C@@]1(C)OC(O[C@]23CC[C@@]4(C[C@H]12)[C@H]1Cc2ccc(O)c5O[C@@H]3[C@]4(CCN1CC1CC1)c25)c1ccccc1 |r,TLB:4:14:25.24:11.10| Show InChI InChI=1S/C35H43NO4/c1-31(2,3)32(4)25-19-33-14-15-35(25,40-29(39-32)22-8-6-5-7-9-22)30-34(33)16-17-36(20-21-10-11-21)26(33)18-23-12-13-24(37)28(38-30)27(23)34/h5-9,12-13,21,25-26,29-30,37H,10-11,14-20H2,1-4H3/t25-,26-,29?,30-,32+,33-,34+,35-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>20	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Functional [35S]GTPγS binding assays were conducted as follows. κ opioid receptor membrane solution was prepared by sequentially adding f...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM222963 (US9315514, 11) Show SMILES CC(C)(C)[C@@]1(C)OCO[C@]23C=C[C@@]4(C[C@H]12)[C@H]1Cc2ccc(O)c5O[C@@H]3[C@]4(CCN1CC1CC1)c25 |r,c:10,TLB:4:14:25.24:11.10| Show InChI InChI=1S/C29H37NO4/c1-25(2,3)26(4)20-14-27-9-10-29(20,33-16-32-26)24-28(27)11-12-30(15-17-5-6-17)21(27)13-18-7-8-19(31)23(34-24)22(18)28/h7-10,17,20-21,24,31H,5-6,11-16H2,1-4H3/t20-,21-,24-,26+,27-,28+,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.76	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Functional [35S]GTPγS binding assays were conducted as follows. κ opioid receptor membrane solution was prepared by sequentially adding f...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM222964 (US9315514, 12) Show SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@]12OCO[C@@](C)([C@H]1C[C@]35C=C2)C(C)(C)C |r,wU:15.22,26.31,16.17,20.24,24.28,wD:28.32,7.7,24.38,c:36,THB:24:26:15.16:29.30,(-5.66,6.41,;-4.41,5.57,;-4.51,4.07,;-5.84,3.3,;-5.78,1.78,;-4.58,.83,;-4.24,-.67,;-2.82,-1.39,;-3.66,-2.77,;-4.98,-3.5,;-5,-5.01,;-4.27,-6.32,;-5.78,-6.3,;-2.13,-2.79,;-1.89,-1.21,;-1.87,.53,;-.88,2.03,;-1.72,3.37,;-3.26,3.12,;-3.19,1.53,;.82,2.54,;1.44,3.95,;2.97,3.84,;3.61,2.41,;3.17,.89,;2.96,-.6,;1.59,1,;.76,-.5,;-1,-.87,;-.25,.18,;.23,1.41,;4.64,.58,;6.11,.26,;4.95,2.05,;4.32,-.89,)| Show InChI InChI=1S/C30H39NO4/c1-26(2,3)27(4)21-15-28-10-11-30(21,34-17-33-27)25-29(28)12-13-31(16-18-6-7-18)22(28)14-19-8-9-20(32-5)24(35-25)23(19)29/h8-11,18,21-22,25H,6-7,12-17H2,1-5H3/t21-,22-,25-,27+,28-,29+,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	593	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Functional [35S]GTPγS binding assays were conducted as follows. κ opioid receptor membrane solution was prepared by sequentially adding f...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM222965 (US9315514, 8) Show SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@]12CC[C@@]35C[C@@H]1[C@](C)(OCO2)C(C)(C)C |r,THB:26:25:15.16:22.21| Show InChI InChI=1S/C30H41NO4/c1-26(2,3)27(4)21-15-28-10-11-30(21,34-17-33-27)25-29(28)12-13-31(16-18-6-7-18)22(28)14-19-8-9-20(32-5)24(35-25)23(19)29/h8-9,18,21-22,25H,6-7,10-17H2,1-5H3/t21-,22-,25-,27+,28-,29+,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	855	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description Functional [35S]GTPγS binding assays were conducted as follows. κ opioid receptor membrane solution was prepared by sequentially adding f...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM222966 (US9315514, 7) Show SMILES CC(C)(C)[C@@]1(C)OCO[C@]23CC[C@@]4(C[C@H]12)[C@H]1Cc2ccc(OCc5ccccc5)c5O[C@@H]3[C@]4(CCN1CC1CC1)c25 |r,TLB:4:14:32.31:11.10| Show InChI InChI=1S/C36H45NO4/c1-32(2,3)33(4)27-19-34-14-15-36(27,40-22-39-33)31-35(34)16-17-37(20-23-10-11-23)28(34)18-25-12-13-26(30(41-31)29(25)35)38-21-24-8-6-5-7-9-24/h5-9,12-13,23,27-28,31H,10-11,14-22H2,1-4H3/t27-,28-,31-,33+,34-,35+,36-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	950	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description [35S]GTPγS functional assays were conducted using freshly thawed μ-receptor membranes prepared in-house from a cell line expressing recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM222965 (US9315514, 8) Show SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@]12CC[C@@]35C[C@@H]1[C@](C)(OCO2)C(C)(C)C |r,THB:26:25:15.16:22.21| Show InChI InChI=1S/C30H41NO4/c1-26(2,3)27(4)21-15-28-10-11-30(21,34-17-33-27)25-29(28)12-13-31(16-18-6-7-18)22(28)14-19-8-9-20(32-5)24(35-25)23(19)29/h8-9,18,21-22,25H,6-7,10-17H2,1-5H3/t21-,22-,25-,27+,28-,29+,30-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	85.4	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description [35S]GTPγS functional assays were conducted using freshly thawed μ-receptor membranes prepared in-house from a cell line expressing recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM222964 (US9315514, 12) Show SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@]12OCO[C@@](C)([C@H]1C[C@]35C=C2)C(C)(C)C |r,wU:15.22,26.31,16.17,20.24,24.28,wD:28.32,7.7,24.38,c:36,THB:24:26:15.16:29.30,(-5.66,6.41,;-4.41,5.57,;-4.51,4.07,;-5.84,3.3,;-5.78,1.78,;-4.58,.83,;-4.24,-.67,;-2.82,-1.39,;-3.66,-2.77,;-4.98,-3.5,;-5,-5.01,;-4.27,-6.32,;-5.78,-6.3,;-2.13,-2.79,;-1.89,-1.21,;-1.87,.53,;-.88,2.03,;-1.72,3.37,;-3.26,3.12,;-3.19,1.53,;.82,2.54,;1.44,3.95,;2.97,3.84,;3.61,2.41,;3.17,.89,;2.96,-.6,;1.59,1,;.76,-.5,;-1,-.87,;-.25,.18,;.23,1.41,;4.64,.58,;6.11,.26,;4.95,2.05,;4.32,-.89,)| Show InChI InChI=1S/C30H39NO4/c1-26(2,3)27(4)21-15-28-10-11-30(21,34-17-33-27)25-29(28)12-13-31(16-18-6-7-18)22(28)14-19-8-9-20(32-5)24(35-25)23(19)29/h8-11,18,21-22,25H,6-7,12-17H2,1-5H3/t21-,22-,25-,27+,28-,29+,30-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	460	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description [35S]GTPγS functional assays were conducted using freshly thawed μ-receptor membranes prepared in-house from a cell line expressing recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM222963 (US9315514, 11) Show SMILES CC(C)(C)[C@@]1(C)OCO[C@]23C=C[C@@]4(C[C@H]12)[C@H]1Cc2ccc(O)c5O[C@@H]3[C@]4(CCN1CC1CC1)c25 |r,c:10,TLB:4:14:25.24:11.10| Show InChI InChI=1S/C29H37NO4/c1-25(2,3)26(4)20-14-27-9-10-29(20,33-16-32-26)24-28(27)11-12-30(15-17-5-6-17)21(27)13-18-7-8-19(31)23(34-24)22(18)28/h7-10,17,20-21,24,31H,5-6,11-16H2,1-4H3/t20-,21-,24-,26+,27-,28+,29-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.56	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description [35S]GTPγS functional assays were conducted using freshly thawed μ-receptor membranes prepared in-house from a cell line expressing recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM222962 (US9315514, 6) Show SMILES CC(C)(C)[C@@]1(C)OC(O[C@]23CC[C@@]4(C[C@H]12)[C@H]1Cc2ccc(O)c5O[C@@H]3[C@]4(CCN1CC1CC1)c25)c1ccccc1 |r,TLB:4:14:25.24:11.10| Show InChI InChI=1S/C35H43NO4/c1-31(2,3)32(4)25-19-33-14-15-35(25,40-29(39-32)22-8-6-5-7-9-22)30-34(33)16-17-36(20-21-10-11-21)26(33)18-23-12-13-24(37)28(38-30)27(23)34/h5-9,12-13,21,25-26,29-30,37H,10-11,14-20H2,1-4H3/t25-,26-,29?,30-,32+,33-,34+,35-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.35	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description [35S]GTPγS functional assays were conducted using freshly thawed μ-receptor membranes prepared in-house from a cell line expressing recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM222959 (US9315514, 3) Show SMILES CC(C)(C)[C@@]1(C)OCO[C@]23CC[C@@]4(C[C@H]12)[C@H]1Cc2ccc(O)c5O[C@@H]3[C@]4(CCN1CC1CC1)c25 |r,TLB:4:14:25.24:11.10| Show InChI InChI=1S/C29H39NO4/c1-25(2,3)26(4)20-14-27-9-10-29(20,33-16-32-26)24-28(27)11-12-30(15-17-5-6-17)21(27)13-18-7-8-19(31)23(34-24)22(18)28/h7-8,17,20-21,24,31H,5-6,9-16H2,1-4H3/t20-,21-,24-,26+,27-,28+,29-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.860	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description [35S]GTPγS functional assays were conducted using freshly thawed μ-receptor membranes prepared in-house from a cell line expressing recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM222960 (US9315514, 4) Show SMILES CCC1O[C@@](C)([C@H]2C[C@]34CC[C@]2(O1)[C@@H]1Oc2c5c(C[C@H]3N(CC3CC3)CC[C@@]415)ccc2O)C(C)(C)C |r,TLB:4:6:27.13:9.10| Show InChI InChI=1S/C31H43NO4/c1-6-23-35-28(5,27(2,3)4)21-16-29-11-12-31(21,36-23)26-30(29)13-14-32(17-18-7-8-18)22(29)15-19-9-10-20(33)25(34-26)24(19)30/h9-10,18,21-23,26,33H,6-8,11-17H2,1-5H3/t21-,22-,23?,26-,28+,29-,30+,31-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.40	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description [35S]GTPγS functional assays were conducted using freshly thawed μ-receptor membranes prepared in-house from a cell line expressing recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM222961 (US9315514, 5) Show SMILES CCCC1O[C@@](C)([C@H]2C[C@]34CC[C@]2(O1)[C@@H]1Oc2c5c(C[C@H]3N(CC3CC3)CC[C@@]415)ccc2O)C(C)(C)C |r,TLB:5:7:28.14:10.11| Show InChI InChI=1S/C32H45NO4/c1-6-7-24-36-29(5,28(2,3)4)22-17-30-12-13-32(22,37-24)27-31(30)14-15-33(18-19-8-9-19)23(30)16-20-10-11-21(34)26(35-27)25(20)31/h10-11,19,22-24,27,34H,6-9,12-18H2,1-5H3/t22-,23-,24?,27-,29+,30-,31+,32-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.54	n/a	n/a	7.4	25
Rhodes Technologies US Patent					Assay Description [35S]GTPγS functional assays were conducted using freshly thawed μ-receptor membranes prepared in-house from a cell line expressing recombin...				US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC
					More data for this Ligand-Target Pair