Compile Data Set for Download or QSAR

Found 50 hits with Last Name = 'ripka' and Initial = 'as'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rhizopuspepsin (Rhizopus microsporus var. chinensis)	BDBM50070005 (((3R,6R,15R)-15-Hydroxymethyl-3-isopropyl-2,5-diox...) Show SMILES CC(C)[C@H]1NC(=O)[C@@H](CCCCCCCC[C@H](CO)NC1=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C22H41N3O5/c1-15(2)18-20(28)23-16(14-26)12-10-8-6-7-9-11-13-17(19(27)25-18)24-21(29)30-22(3,4)5/h15-18,26H,6-14H2,1-5H3,(H,23,28)(H,24,29)(H,25,27)/t16-,17-,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Compound was evaluated for potency towards nicotinic acetylcholine receptor in rat P2 brain membranes using [3H]-nicotine as a radioligand				Bioorg Med Chem Lett 8: 357-60 (1999) BindingDB Entry DOI: 10.7270/Q2N58KH1
					More data for this Ligand-Target Pair
Rhizopuspepsin (Rhizopus microsporus var. chinensis)	BDBM50070006 (((Z)-(3R,6R,15R)-15-Hydroxymethyl-3-isopropyl-2,5-...) Show SMILES CC(C)[C@H]1NC(=O)[C@@H](CCC\C=C/CCC[C@H](CO)NC1=O)NC(=O)OC(C)(C)C |c:11| Show InChI InChI=1S/C22H39N3O5/c1-15(2)18-20(28)23-16(14-26)12-10-8-6-7-9-11-13-17(19(27)25-18)24-21(29)30-22(3,4)5/h6-7,15-18,26H,8-14H2,1-5H3,(H,23,28)(H,24,29)(H,25,27)/b7-6-/t16-,17-,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	336	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Compound was evaluated for inhibitory activity towards nicotinic acetylcholine receptor in rat P2 brain membranes using [3H]-nicotine as a radioligan...				Bioorg Med Chem Lett 8: 357-60 (1999) BindingDB Entry DOI: 10.7270/Q2N58KH1
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190579 (US9181219, 20) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ncccc3Cl)c12 Show InChI InChI=1S/C17H17ClN2OS/c1-12-5-2-6-13-7-4-10-20(16(12)13)15(21)11-22-17-14(18)8-3-9-19-17/h2-3,5-6,8-9H,4,7,10-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190585 (US9181219, 2-{[3-fluoro-5-(trifluoromethyl)pyridin...) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ncc(cc3F)C(F)(F)F)c12 Show InChI InChI=1S/C18H16F4N2OS/c1-11-4-2-5-12-6-3-7-24(16(11)12)15(25)10-26-17-14(19)8-13(9-23-17)18(20,21)22/h2,4-5,8-9H,3,6-7,10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190585 (US9181219, 2-{[3-fluoro-5-(trifluoromethyl)pyridin...) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ncc(cc3F)C(F)(F)F)c12 Show InChI InChI=1S/C18H16F4N2OS/c1-11-4-2-5-12-6-3-7-24(16(11)12)15(25)10-26-17-14(19)8-13(9-23-17)18(20,21)22/h2,4-5,8-9H,3,6-7,10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190576 (US9181219, 6) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ccc(cn3)C(F)(F)F)c12 Show InChI InChI=1S/C18H17F3N2OS/c1-12-4-2-5-13-6-3-9-23(17(12)13)16(24)11-25-15-8-7-14(10-22-15)18(19,20)21/h2,4-5,7-8,10H,3,6,9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190583 (US9181219, 10) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ncc(cc3Cl)C(F)(F)F)c12 Show InChI InChI=1S/C18H16ClF3N2OS/c1-11-4-2-5-12-6-3-7-24(16(11)12)15(25)10-26-17-14(19)8-13(9-23-17)18(20,21)22/h2,4-5,8-9H,3,6-7,10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190593 (US9181219, 2-[(4,5-dimethylpyridin-2-yl)sulfanyl]-...) Show SMILES Cc1cnc(SCC(=O)N2CCCc3cccc(C)c23)cc1C Show InChI InChI=1S/C19H22N2OS/c1-13-6-4-7-16-8-5-9-21(19(13)16)18(22)12-23-17-10-14(2)15(3)11-20-17/h4,6-7,10-11H,5,8-9,12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190593 (US9181219, 2-[(4,5-dimethylpyridin-2-yl)sulfanyl]-...) Show SMILES Cc1cnc(SCC(=O)N2CCCc3cccc(C)c23)cc1C Show InChI InChI=1S/C19H22N2OS/c1-13-6-4-7-16-8-5-9-21(19(13)16)18(22)12-23-17-10-14(2)15(3)11-20-17/h4,6-7,10-11H,5,8-9,12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190588 (US9181219, 2-[(3,5-dichloropyridin-2-yl)sulfanyl]-...) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ncc(Cl)cc3Cl)c12 Show InChI InChI=1S/C17H16Cl2N2OS/c1-11-4-2-5-12-6-3-7-21(16(11)12)15(22)10-23-17-14(19)8-13(18)9-20-17/h2,4-5,8-9H,3,6-7,10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190588 (US9181219, 2-[(3,5-dichloropyridin-2-yl)sulfanyl]-...) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ncc(Cl)cc3Cl)c12 Show InChI InChI=1S/C17H16Cl2N2OS/c1-11-4-2-5-12-6-3-7-21(16(11)12)15(22)10-23-17-14(19)8-13(18)9-20-17/h2,4-5,8-9H,3,6-7,10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190586 (US9181219, 2-[(5-bromopyridin-2-yl)sulfanyl]-1-(8-...) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ccc(Br)cn3)c12 Show InChI InChI=1S/C17H17BrN2OS/c1-12-4-2-5-13-6-3-9-20(17(12)13)16(21)11-22-15-8-7-14(18)10-19-15/h2,4-5,7-8,10H,3,6,9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190578 (US9181219, 16) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ccc(Cl)cn3)c12 Show InChI InChI=1S/C17H17ClN2OS/c1-12-4-2-5-13-6-3-9-20(17(12)13)16(21)11-22-15-8-7-14(18)10-19-15/h2,4-5,7-8,10H,3,6,9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190576 (US9181219, 6) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ccc(cn3)C(F)(F)F)c12 Show InChI InChI=1S/C18H17F3N2OS/c1-12-4-2-5-13-6-3-9-23(17(12)13)16(24)11-25-15-8-7-14(10-22-15)18(19,20)21/h2,4-5,7-8,10H,3,6,9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190591 (US9181219, 2-[(3-chloropyridin-2-yl)sulfanyl]-1-(8...) Show SMILES COc1cccc2CCCN(C(=O)CSc3ncccc3Cl)c12 Show InChI InChI=1S/C17H17ClN2O2S/c1-22-14-8-2-5-12-6-4-10-20(16(12)14)15(21)11-23-17-13(18)7-3-9-19-17/h2-3,5,7-9H,4,6,10-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190590 (US9181219, 2-{[2-(8-methyl-1,2,3,4-tetrahydroquino...) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ncccc3C#N)c12 Show InChI InChI=1S/C18H17N3OS/c1-13-5-2-6-14-8-4-10-21(17(13)14)16(22)12-23-18-15(11-19)7-3-9-20-18/h2-3,5-7,9H,4,8,10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190586 (US9181219, 2-[(5-bromopyridin-2-yl)sulfanyl]-1-(8-...) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ccc(Br)cn3)c12 Show InChI InChI=1S/C17H17BrN2OS/c1-12-4-2-5-13-6-3-9-20(17(12)13)16(21)11-22-15-8-7-14(18)10-19-15/h2,4-5,7-8,10H,3,6,9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190583 (US9181219, 10) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ncc(cc3Cl)C(F)(F)F)c12 Show InChI InChI=1S/C18H16ClF3N2OS/c1-11-4-2-5-12-6-3-7-24(16(11)12)15(25)10-26-17-14(19)8-13(9-23-17)18(20,21)22/h2,4-5,8-9H,3,6-7,10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190578 (US9181219, 16) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ccc(Cl)cn3)c12 Show InChI InChI=1S/C17H17ClN2OS/c1-12-4-2-5-13-6-3-9-20(17(12)13)16(21)11-22-15-8-7-14(18)10-19-15/h2,4-5,7-8,10H,3,6,9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190591 (US9181219, 2-[(3-chloropyridin-2-yl)sulfanyl]-1-(8...) Show SMILES COc1cccc2CCCN(C(=O)CSc3ncccc3Cl)c12 Show InChI InChI=1S/C17H17ClN2O2S/c1-22-14-8-2-5-12-6-4-10-20(16(12)14)15(21)11-23-17-13(18)7-3-9-19-17/h2-3,5,7-9H,4,6,10-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190592 (US9181219, 2-[(3,4-dimethylpyridin-2-yl)sulfanyl]-...) Show SMILES Cc1ccnc(SCC(=O)N2CCCc3cccc(C)c23)c1C Show InChI InChI=1S/C19H22N2OS/c1-13-9-10-20-19(15(13)3)23-12-17(22)21-11-5-8-16-7-4-6-14(2)18(16)21/h4,6-7,9-10H,5,8,11-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190581 (US9181219, 8) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ncccc3C(F)(F)F)c12 Show InChI InChI=1S/C18H17F3N2OS/c1-12-5-2-6-13-7-4-10-23(16(12)13)15(24)11-25-17-14(18(19,20)21)8-3-9-22-17/h2-3,5-6,8-9H,4,7,10-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190575 (US9181219, 1-(1,2,3,4-tetrahydroquinolin-1-yl)-2-{...) Show SMILES FC(F)(F)c1ccc(SCC(=O)N2CCCc3ccccc23)nc1 Show InChI InChI=1S/C17H15F3N2OS/c18-17(19,20)13-7-8-15(21-10-13)24-11-16(23)22-9-3-5-12-4-1-2-6-14(12)22/h1-2,4,6-8,10H,3,5,9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190579 (US9181219, 20) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ncccc3Cl)c12 Show InChI InChI=1S/C17H17ClN2OS/c1-12-5-2-6-13-7-4-10-20(16(12)13)15(21)11-22-17-14(18)8-3-9-19-17/h2-3,5-6,8-9H,4,7,10-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190590 (US9181219, 2-{[2-(8-methyl-1,2,3,4-tetrahydroquino...) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ncccc3C#N)c12 Show InChI InChI=1S/C18H17N3OS/c1-13-5-2-6-14-8-4-10-21(17(13)14)16(22)12-23-18-15(11-19)7-3-9-20-18/h2-3,5-7,9H,4,8,10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190584 (US9181219, 6-{[2-(8-methyl-1,2,3,4-tetrahydroquino...) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ccc(cn3)C#N)c12 Show InChI InChI=1S/C18H17N3OS/c1-13-4-2-5-15-6-3-9-21(18(13)15)17(22)12-23-16-8-7-14(10-19)11-20-16/h2,4-5,7-8,11H,3,6,9,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM190578 (US9181219, 16) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ccc(Cl)cn3)c12 Show InChI InChI=1S/C17H17ClN2OS/c1-12-4-2-5-13-6-3-9-20(17(12)13)16(21)11-22-15-8-7-14(18)10-19-15/h2,4-5,7-8,10H,3,6,9,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190587 (US9181219, methyl 5-chloro-6-{[2-(8-methyl-1,2,3,4...) Show SMILES COC(=O)c1cnc(SCC(=O)N2CCCc3cccc(C)c23)c(Cl)c1 Show InChI InChI=1S/C19H19ClN2O3S/c1-12-5-3-6-13-7-4-8-22(17(12)13)16(23)11-26-18-15(20)9-14(10-21-18)19(24)25-2/h3,5-6,9-10H,4,7-8,11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190580 (US9181219, 12) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ccccn3)c12 Show InChI InChI=1S/C17H18N2OS/c1-13-6-4-7-14-8-5-11-19(17(13)14)16(20)12-21-15-9-2-3-10-18-15/h2-4,6-7,9-10H,5,8,11-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190587 (US9181219, methyl 5-chloro-6-{[2-(8-methyl-1,2,3,4...) Show SMILES COC(=O)c1cnc(SCC(=O)N2CCCc3cccc(C)c23)c(Cl)c1 Show InChI InChI=1S/C19H19ClN2O3S/c1-12-5-3-6-13-7-4-8-22(17(12)13)16(23)11-26-18-15(20)9-14(10-21-18)19(24)25-2/h3,5-6,9-10H,4,7-8,11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190577 (US9181219, 21) Show SMILES Clc1ccc(SCC(=O)N2CCCc3ccccc23)nc1 Show InChI InChI=1S/C16H15ClN2OS/c17-13-7-8-15(18-10-13)21-11-16(20)19-9-3-5-12-4-1-2-6-14(12)19/h1-2,4,6-8,10H,3,5,9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190575 (US9181219, 1-(1,2,3,4-tetrahydroquinolin-1-yl)-2-{...) Show SMILES FC(F)(F)c1ccc(SCC(=O)N2CCCc3ccccc23)nc1 Show InChI InChI=1S/C17H15F3N2OS/c18-17(19,20)13-7-8-15(21-10-13)24-11-16(23)22-9-3-5-12-4-1-2-6-14(12)22/h1-2,4,6-8,10H,3,5,9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190592 (US9181219, 2-[(3,4-dimethylpyridin-2-yl)sulfanyl]-...) Show SMILES Cc1ccnc(SCC(=O)N2CCCc3cccc(C)c23)c1C Show InChI InChI=1S/C19H22N2OS/c1-13-9-10-20-19(15(13)3)23-12-17(22)21-11-5-8-16-7-4-6-14(2)18(16)21/h4,6-7,9-10H,5,8,11-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190582 (US9181219, 24) Show SMILES Cc1ccc(SCC(=O)N2CCCc3cccc(C)c23)nc1 Show InChI InChI=1S/C18H20N2OS/c1-13-8-9-16(19-11-13)22-12-17(21)20-10-4-7-15-6-3-5-14(2)18(15)20/h3,5-6,8-9,11H,4,7,10,12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190581 (US9181219, 8) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ncccc3C(F)(F)F)c12 Show InChI InChI=1S/C18H17F3N2OS/c1-12-5-2-6-13-7-4-10-23(16(12)13)15(24)11-25-17-14(18(19,20)21)8-3-9-22-17/h2-3,5-6,8-9H,4,7,10-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190577 (US9181219, 21) Show SMILES Clc1ccc(SCC(=O)N2CCCc3ccccc23)nc1 Show InChI InChI=1S/C16H15ClN2OS/c17-13-7-8-15(18-10-13)21-11-16(20)19-9-3-5-12-4-1-2-6-14(12)19/h1-2,4,6-8,10H,3,5,9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190594 (US9181219, 2-{[3-ethyl-5-(trifluoromethyl)pyridin-...) Show SMILES CCc1cc(cnc1SCC(=O)N1CCCc2cccc(C)c12)C(F)(F)F Show InChI InChI=1S/C20H21F3N2OS/c1-3-14-10-16(20(21,22)23)11-24-19(14)27-12-17(26)25-9-5-8-15-7-4-6-13(2)18(15)25/h4,6-7,10-11H,3,5,8-9,12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190594 (US9181219, 2-{[3-ethyl-5-(trifluoromethyl)pyridin-...) Show SMILES CCc1cc(cnc1SCC(=O)N1CCCc2cccc(C)c12)C(F)(F)F Show InChI InChI=1S/C20H21F3N2OS/c1-3-14-10-16(20(21,22)23)11-24-19(14)27-12-17(26)25-9-5-8-15-7-4-6-13(2)18(15)25/h4,6-7,10-11H,3,5,8-9,12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM190579 (US9181219, 20) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ncccc3Cl)c12 Show InChI InChI=1S/C17H17ClN2OS/c1-12-5-2-6-13-7-4-10-20(16(12)13)15(21)11-22-17-14(18)8-3-9-19-17/h2-3,5-6,8-9H,4,7,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190582 (US9181219, 24) Show SMILES Cc1ccc(SCC(=O)N2CCCc3cccc(C)c23)nc1 Show InChI InChI=1S/C18H20N2OS/c1-13-8-9-16(19-11-13)22-12-17(21)20-10-4-7-15-6-3-5-14(2)18(15)20/h3,5-6,8-9,11H,4,7,10,12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190580 (US9181219, 12) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ccccn3)c12 Show InChI InChI=1S/C17H18N2OS/c1-13-6-4-7-14-8-5-11-19(17(13)14)16(20)12-21-15-9-2-3-10-18-15/h2-4,6-7,9-10H,5,8,11-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190589 (US9181219, 2-{[2-(8-methyl-1,2,3,4-tetrahydroquino...) Show SMILES Cc1cccc2CCCN(C(=O)CSc3cc(ccn3)C#N)c12 Show InChI InChI=1S/C18H17N3OS/c1-13-4-2-5-15-6-3-9-21(18(13)15)17(22)12-23-16-10-14(11-19)7-8-20-16/h2,4-5,7-8,10H,3,6,9,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190589 (US9181219, 2-{[2-(8-methyl-1,2,3,4-tetrahydroquino...) Show SMILES Cc1cccc2CCCN(C(=O)CSc3cc(ccn3)C#N)c12 Show InChI InChI=1S/C18H17N3OS/c1-13-4-2-5-15-6-3-9-21(18(13)15)17(22)12-23-16-10-14(11-19)7-8-20-16/h2,4-5,7-8,10H,3,6,9,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM190584 (US9181219, 6-{[2-(8-methyl-1,2,3,4-tetrahydroquino...) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ccc(cn3)C#N)c12 Show InChI InChI=1S/C18H17N3OS/c1-13-4-2-5-15-6-3-9-21(18(13)15)17(22)12-23-16-8-7-14(10-19)11-20-16/h2,4-5,7-8,11H,3,6,9,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM190576 (US9181219, 6) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ccc(cn3)C(F)(F)F)c12 Show InChI InChI=1S/C18H17F3N2OS/c1-12-4-2-5-13-6-3-9-23(17(12)13)16(24)11-25-15-8-7-14(10-22-15)18(19,20)21/h2,4-5,7-8,10H,3,6,9,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM190579 (US9181219, 20) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ncccc3Cl)c12 Show InChI InChI=1S/C17H17ClN2OS/c1-12-5-2-6-13-7-4-10-20(16(12)13)15(21)11-22-17-14(18)8-3-9-19-17/h2-3,5-6,8-9H,4,7,10-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM190576 (US9181219, 6) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ccc(cn3)C(F)(F)F)c12 Show InChI InChI=1S/C18H17F3N2OS/c1-12-4-2-5-13-6-3-9-23(17(12)13)16(24)11-25-15-8-7-14(10-22-15)18(19,20)21/h2,4-5,7-8,10H,3,6,9,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM190578 (US9181219, 16) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ccc(Cl)cn3)c12 Show InChI InChI=1S/C17H17ClN2OS/c1-12-4-2-5-13-6-3-9-20(17(12)13)16(21)11-22-15-8-7-14(18)10-19-15/h2,4-5,7-8,10H,3,6,9,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM190576 (US9181219, 6) Show SMILES Cc1cccc2CCCN(C(=O)CSc3ccc(cn3)C(F)(F)F)c12 Show InChI InChI=1S/C18H17F3N2OS/c1-12-4-2-5-13-6-3-9-23(17(12)13)16(24)11-25-15-8-7-14(10-22-15)18(19,20)21/h2,4-5,7-8,10H,3,6,9,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM190575 (US9181219, 1-(1,2,3,4-tetrahydroquinolin-1-yl)-2-{...) Show SMILES FC(F)(F)c1ccc(SCC(=O)N2CCCc3ccccc23)nc1 Show InChI InChI=1S/C17H15F3N2OS/c18-17(19,20)13-7-8-15(21-10-13)24-11-16(23)22-9-3-5-12-4-1-2-6-14(12)22/h1-2,4,6-8,10H,3,5,9,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
HYDRA BIOSCIENCES, INC. US Patent					Assay Description To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...				US Patent US9181219 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HPH
					More data for this Ligand-Target Pair