| Reaction Details |
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 | Report a problem with these data |
| Target | Transient receptor potential cation channel subfamily V member 3 |
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| Ligand | BDBM190578 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | <500±n/a nM |
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| Citation |  Moran, MM; Chong, JA; Fanger, C; Ripka, AS; Larsen, GR; Zhen, X; Underwood, DJ; Weigele, M Compounds of modulating TRPV3 function US Patent US9181219 Publication Date 11/10/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Transient receptor potential cation channel subfamily V member 3 |
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| Name: | Transient receptor potential cation channel subfamily V member 3 |
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| Synonyms: | TRPV3 | TRPV3_HUMAN | Transient receptor potential cation channel subfamily V member 3 (TRPV3) | Vanilloid receptor-like 3 |
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| Type: | Enzyme |
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| Mol. Mass.: | 90635.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8NET8 |
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| Residue: | 790 |
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| Sequence: | MKAHPKEMVPLMGKRVAAPSGNPAILPEKRPAEITPTKKSAHFFLEIEGFEPNPTVAKTS
PPVFSKPMDSNIRQCISGNCDDMDSPQSPQDDVTETPSNPNSPSAQLAKEEQRRKKRRLK
KRIFAAVSEGCVEELVELLVELQELCRRRHDEDVPDFLMHKLTASDTGKTCLMKALLNIN
PNTKEIVRILLAFAEENDILGRFINAEYTEEAYEGQTALNIAIERRQGDIAALLIAAGAD
VNAHAKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNIL
HALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYI
LSREIKEKRLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLEITVYNTNIDNRHEML
TLEPLHTLLHMKWKKFAKHMFFLSFCFYFFYNITLTLVSYYRPREEEAIPHPLALTHKMG
WLQLLGRMFVLIWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFVFFIQAVLVILSVFLY
LFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYIVFLLG
FGVALASLIEKCPKDNKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLIT
YVILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGEL
CKVAEDDFRLCLRINEVKWTEWKTHVSFLNEDPGPVRRTDFNKIQDSSRNNSKTTLNAFE
EVEEFPETSV
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| BDBM190578 |
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| n/a |
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| Name | BDBM190578 |
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| Synonyms: | US9181219, 16 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H17ClN2OS |
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| Mol. Mass. | 332.848 |
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| SMILES | Cc1cccc2CCCN(C(=O)CSc3ccc(Cl)cn3)c12 |
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| Structure | 
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