Compile Data Set for Download or QSAR

Found 64 hits with Last Name = 'sasho' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50237869 ((+/-)-2-(1,3-bis(2-(2-methylpyrrolidin-1-yl)ethyl)...) Show SMILES [#6]-[#6]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-2-[#6])\[#6]-1=[#6](/C#N)C#N |w:1.0,18.20| Show InChI InChI=1S/C20H32N6/c1-17-5-3-7-23(17)9-11-25-13-14-26(20(25)19(15-21)16-22)12-10-24-8-4-6-18(24)2/h17-18H,3-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cells				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50237870 (2-(1,3-bis(2-((S)-2-methylpyrrolidin-1-yl)ethyl)im...) Show SMILES [#6]-[#6@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6@@H]-2-[#6])\[#6]-1=[#6](/C#N)C#N Show InChI InChI=1S/C20H32N6/c1-17-5-3-7-23(17)9-11-25-13-14-26(20(25)19(15-21)16-22)12-10-24-8-4-6-18(24)2/h17-18H,3-14H2,1-2H3/t17-,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cells				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50237874 ((+/-)-2-(1-(2-(2-methylpyrrolidin-1-yl)ethyl)-3-(2...) Show SMILES [#6]-[#6]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)\[#6]-1=[#6](/C#N)C#N |w:1.0| Show InChI InChI=1S/C20H32N6/c1-18-6-5-9-24(18)12-13-26-15-14-25(20(26)19(16-21)17-22)11-10-23-7-3-2-4-8-23/h18H,2-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cells				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50237872 (2-(3-(2-((R)-2-methylpyrrolidin-1-yl)ethyl)-1-(2-(...) Show SMILES [#6]-[#6@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6@H]-2-[#6])\[#6]-1=[#6](\C#N)C#N Show InChI InChI=1S/C20H32N6/c1-17-5-3-7-23(17)9-11-25-13-14-26(20(25)19(15-21)16-22)12-10-24-8-4-6-18(24)2/h17-18H,3-14H2,1-2H3/t17-,18+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cells				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50237870 (2-(1,3-bis(2-((S)-2-methylpyrrolidin-1-yl)ethyl)im...) Show SMILES [#6]-[#6@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6@@H]-2-[#6])\[#6]-1=[#6](/C#N)C#N Show InChI InChI=1S/C20H32N6/c1-17-5-3-7-23(17)9-11-25-13-14-26(20(25)19(15-21)16-22)12-10-24-8-4-6-18(24)2/h17-18H,3-14H2,1-2H3/t17-,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membrane				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159110 (1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...) Show SMILES C(COc1ccc(CN2CCCCC2)cc1)CN1CCCCC1 Show InChI InChI=1S/C20H32N2O/c1-3-12-21(13-4-1)16-7-17-23-20-10-8-19(9-11-20)18-22-14-5-2-6-15-22/h8-11H,1-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cells				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50237869 ((+/-)-2-(1,3-bis(2-(2-methylpyrrolidin-1-yl)ethyl)...) Show SMILES [#6]-[#6]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-2-[#6])\[#6]-1=[#6](/C#N)C#N |w:1.0,18.20| Show InChI InChI=1S/C20H32N6/c1-17-5-3-7-23(17)9-11-25-13-14-26(20(25)19(15-21)16-22)12-10-24-8-4-6-18(24)2/h17-18H,3-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membrane				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50237874 ((+/-)-2-(1-(2-(2-methylpyrrolidin-1-yl)ethyl)-3-(2...) Show SMILES [#6]-[#6]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)\[#6]-1=[#6](/C#N)C#N |w:1.0| Show InChI InChI=1S/C20H32N6/c1-18-6-5-9-24(18)12-13-26-15-14-25(20(26)19(16-21)17-22)11-10-23-7-3-2-4-8-23/h18H,2-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membrane				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50237872 (2-(3-(2-((R)-2-methylpyrrolidin-1-yl)ethyl)-1-(2-(...) Show SMILES [#6]-[#6@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6@H]-2-[#6])\[#6]-1=[#6](\C#N)C#N Show InChI InChI=1S/C20H32N6/c1-17-5-3-7-23(17)9-11-25-13-14-26(20(25)19(15-21)16-22)12-10-24-8-4-6-18(24)2/h17-18H,3-14H2,1-2H3/t17-,18+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membrane				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50237875 (2-(1,3-bis(2-((R)-2-methylpyrrolidin-1-yl)ethyl)im...) Show SMILES [#6]-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6@H]-2-[#6])\[#6]-1=[#6](/C#N)C#N Show InChI InChI=1S/C20H32N6/c1-17-5-3-7-23(17)9-11-25-13-14-26(20(25)19(15-21)16-22)12-10-24-8-4-6-18(24)2/h17-18H,3-14H2,1-2H3/t17-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membrane				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50159110 (1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...) Show SMILES C(COc1ccc(CN2CCCCC2)cc1)CN1CCCCC1 Show InChI InChI=1S/C20H32N2O/c1-3-12-21(13-4-1)16-7-17-23-20-10-8-19(9-11-20)18-22-14-5-2-6-15-22/h8-11H,1-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membrane				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50237875 (2-(1,3-bis(2-((R)-2-methylpyrrolidin-1-yl)ethyl)im...) Show SMILES [#6]-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6@H]-2-[#6])\[#6]-1=[#6](/C#N)C#N Show InChI InChI=1S/C20H32N6/c1-17-5-3-7-23(17)9-11-25-13-14-26(20(25)19(15-21)16-22)12-10-24-8-4-6-18(24)2/h17-18H,3-14H2,1-2H3/t17-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cells				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50237878 (2-(1,3-bis(3-(piperidin-1-yl)propyl)imidazolidin-2...) Show SMILES N#C\[#6](C#N)=[#6]-1\[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C22H36N6/c23-19-21(20-24)22-27(15-7-13-25-9-3-1-4-10-25)17-18-28(22)16-8-14-26-11-5-2-6-12-26/h1-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cells				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50237878 (2-(1,3-bis(3-(piperidin-1-yl)propyl)imidazolidin-2...) Show SMILES N#C\[#6](C#N)=[#6]-1\[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C22H36N6/c23-19-21(20-24)22-27(15-7-13-25-9-3-1-4-10-25)17-18-28(22)16-8-14-26-11-5-2-6-12-26/h1-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membrane				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50237871 (2-(1-(2-(piperidin-1-yl)ethyl)-3-(3-(piperidin-1-y...) Show SMILES N#C\[#6](C#N)=[#6]-1/[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C21H34N6/c22-18-20(19-23)21-26(13-7-12-24-8-3-1-4-9-24)16-17-27(21)15-14-25-10-5-2-6-11-25/h1-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membrane				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50237871 (2-(1-(2-(piperidin-1-yl)ethyl)-3-(3-(piperidin-1-y...) Show SMILES N#C\[#6](C#N)=[#6]-1/[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C21H34N6/c22-18-20(19-23)21-26(13-7-12-24-8-3-1-4-9-24)16-17-27(21)15-14-25-10-5-2-6-11-25/h1-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cells				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50237873 (2-(1-(4-(piperidin-1-yl)butyl)-3-(2-(piperidin-1-y...) Show SMILES N#C\[#6](C#N)=[#6]-1/[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C22H36N6/c23-19-21(20-24)22-27(14-8-7-13-25-9-3-1-4-10-25)17-18-28(22)16-15-26-11-5-2-6-12-26/h1-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membrane				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50237873 (2-(1-(4-(piperidin-1-yl)butyl)-3-(2-(piperidin-1-y...) Show SMILES N#C\[#6](C#N)=[#6]-1/[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C22H36N6/c23-19-21(20-24)22-27(14-8-7-13-25-9-3-1-4-10-25)17-18-28(22)16-15-26-11-5-2-6-12-26/h1-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cells				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50237879 (2-(1,3-bis(2-(piperidin-1-yl)ethyl)imidazolidin-2-...) Show SMILES N#C\[#6](C#N)=[#6]-1\[#7](-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C20H32N6/c21-17-19(18-22)20-25(13-11-23-7-3-1-4-8-23)15-16-26(20)14-12-24-9-5-2-6-10-24/h1-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cells				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50237876 (2-(1-(naphthalen-1-ylmethyl)-3-(3-(piperidin-1-yl)...) Show SMILES N#C\[#6](C#N)=[#6]-1\[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#6]-[#6]-[#7]-1-[#6]-c1cccc2ccccc12 Show InChI InChI=1S/C25H29N5/c26-18-23(19-27)25-29(15-7-14-28-12-4-1-5-13-28)16-17-30(25)20-22-10-6-9-21-8-2-3-11-24(21)22/h2-3,6,8-11H,1,4-5,7,12-17,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cells				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50237879 (2-(1,3-bis(2-(piperidin-1-yl)ethyl)imidazolidin-2-...) Show SMILES N#C\[#6](C#N)=[#6]-1\[#7](-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C20H32N6/c21-17-19(18-22)20-25(13-11-23-7-3-1-4-8-23)15-16-26(20)14-12-24-9-5-2-6-10-24/h1-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membrane				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50237877 (2-(1-(2-((3-(dimethylamino)propyl)(ethyl)amino)eth...) Show SMILES [#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7](-[#6])-[#6])-[#6]-[#6]-[#7]1-[#6]-[#6]-[#7](-[#6]-c2cccc3ccccc23)\[#6]-1=[#6](/C#N)C#N Show InChI InChI=1S/C26H34N6/c1-4-30(14-8-13-29(2)3)15-16-31-17-18-32(26(31)24(19-27)20-28)21-23-11-7-10-22-9-5-6-12-25(22)23/h5-7,9-12H,4,8,13-18,21H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membrane				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50237877 (2-(1-(2-((3-(dimethylamino)propyl)(ethyl)amino)eth...) Show SMILES [#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7](-[#6])-[#6])-[#6]-[#6]-[#7]1-[#6]-[#6]-[#7](-[#6]-c2cccc3ccccc23)\[#6]-1=[#6](/C#N)C#N Show InChI InChI=1S/C26H34N6/c1-4-30(14-8-13-29(2)3)15-16-31-17-18-32(26(31)24(19-27)20-28)21-23-11-7-10-22-9-5-6-12-25(22)23/h5-7,9-12H,4,8,13-18,21H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cells				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50237876 (2-(1-(naphthalen-1-ylmethyl)-3-(3-(piperidin-1-yl)...) Show SMILES N#C\[#6](C#N)=[#6]-1\[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#6]-[#6]-[#7]-1-[#6]-c1cccc2ccccc12 Show InChI InChI=1S/C25H29N5/c26-18-23(19-27)25-29(15-7-14-28-12-4-1-5-13-28)16-17-30(25)20-22-10-6-9-21-8-2-3-11-24(21)22/h2-3,6,8-11H,1,4-5,7,12-17,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membrane				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50237870 (2-(1,3-bis(2-((S)-2-methylpyrrolidin-1-yl)ethyl)im...) Show SMILES [#6]-[#6@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6@@H]-2-[#6])\[#6]-1=[#6](/C#N)C#N Show InChI InChI=1S/C20H32N6/c1-17-5-3-7-23(17)9-11-25-13-14-26(20(25)19(15-21)16-22)12-10-24-8-4-6-18(24)2/h17-18H,3-14H2,1-2H3/t17-,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Antagonist activity at histamine H3 receptor in rat forebrain assessed as inhibition of [3H]histamine release from synaptosomes				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50284042 (2-(1-{2-[(5-Piperidin-1-ylmethyl-furan-2-ylmethyl)...) Show SMILES [#6]-c1ccc(cc1)-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-[#6]-c2ccc(-[#6]-[#7]-3-[#6]-[#6]-[#6]-[#6]-[#6]-3)o2)\[#6]-1=[#6](/C#N)C#N Show InChI InChI=1S/C26H32N6O/c1-21-5-7-23(8-6-21)32-16-15-31(26(32)22(17-27)18-28)14-11-29-19-24-9-10-25(33-24)20-30-12-3-2-4-13-30/h5-10,29H,2-4,11-16,19-20H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound against acetylcholinesterase(AChE) from rat brain was determined				Bioorg Med Chem Lett 4: 615-618 (1994) Article DOI: 10.1016/S0960-894X(01)80165-7 BindingDB Entry DOI: 10.7270/Q2FN1659
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50237869 ((+/-)-2-(1,3-bis(2-(2-methylpyrrolidin-1-yl)ethyl)...) Show SMILES [#6]-[#6]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-2-[#6])\[#6]-1=[#6](/C#N)C#N |w:1.0,18.20| Show InChI InChI=1S/C20H32N6/c1-17-5-3-7-23(17)9-11-25-13-14-26(20(25)19(15-21)16-22)12-10-24-8-4-6-18(24)2/h17-18H,3-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Antagonist activity at histamine H3 receptor in rat forebrain assessed as inhibition of [3H]histamine release from synaptosomes				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50284039 (2-(1-{2-[(5-Piperidin-1-ylmethyl-furan-2-ylmethyl)...) Show SMILES [#6]-c1cccc(c1)-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-[#6]-c2ccc(-[#6]-[#7]-3-[#6]-[#6]-[#6]-[#6]-[#6]-3)o2)\[#6]-1=[#6](\C#N)C#N Show InChI InChI=1S/C26H32N6O/c1-21-6-5-7-23(16-21)32-15-14-31(26(32)22(17-27)18-28)13-10-29-19-24-8-9-25(33-24)20-30-11-3-2-4-12-30/h5-9,16,29H,2-4,10-15,19-20H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound against acetylcholinesterase(AChE) from rat brain was determined				Bioorg Med Chem Lett 4: 615-618 (1994) Article DOI: 10.1016/S0960-894X(01)80165-7 BindingDB Entry DOI: 10.7270/Q2FN1659
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50284041 (2-(1-(3-Methoxy-phenyl)-3-{2-[(5-piperidin-1-ylmet...) Show SMILES [#6]-[#8]-c1cccc(c1)-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-[#6]-c2ccc(-[#6]-[#7]-3-[#6]-[#6]-[#6]-[#6]-[#6]-3)o2)\[#6]-1=[#6](\C#N)C#N Show InChI InChI=1S/C26H32N6O2/c1-33-23-7-5-6-22(16-23)32-15-14-31(26(32)21(17-27)18-28)13-10-29-19-24-8-9-25(34-24)20-30-11-3-2-4-12-30/h5-9,16,29H,2-4,10-15,19-20H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound against acetylcholinesterase(AChE) from rat brain was determined				Bioorg Med Chem Lett 4: 615-618 (1994) Article DOI: 10.1016/S0960-894X(01)80165-7 BindingDB Entry DOI: 10.7270/Q2FN1659
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50284043 (2-(1-Phenyl-3-{2-[(5-piperidin-1-ylmethyl-furan-2-...) Show SMILES N#C\[#6](C#N)=[#6]-1/[#7](-[#6]-[#6]-[#7]-[#6]-c2ccc(-[#6]-[#7]-3-[#6]-[#6]-[#6]-[#6]-[#6]-3)o2)-[#6]-[#6]-[#7]-1-c1ccccc1 Show InChI InChI=1S/C25H30N6O/c26-17-21(18-27)25-30(15-16-31(25)22-7-3-1-4-8-22)14-11-28-19-23-9-10-24(32-23)20-29-12-5-2-6-13-29/h1,3-4,7-10,28H,2,5-6,11-16,19-20H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound against acetylcholinesterase(AChE) from rat brain was determined				Bioorg Med Chem Lett 4: 615-618 (1994) Article DOI: 10.1016/S0960-894X(01)80165-7 BindingDB Entry DOI: 10.7270/Q2FN1659
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50284040 (2-(1-(4-Methoxy-phenyl)-3-{2-[(5-piperidin-1-ylmet...) Show SMILES [#6]-[#8]-c1ccc(cc1)-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-[#6]-c2ccc(-[#6]-[#7]-3-[#6]-[#6]-[#6]-[#6]-[#6]-3)o2)\[#6]-1=[#6](/C#N)C#N Show InChI InChI=1S/C26H32N6O2/c1-33-23-7-5-22(6-8-23)32-16-15-31(26(32)21(17-27)18-28)14-11-29-19-24-9-10-25(34-24)20-30-12-3-2-4-13-30/h5-10,29H,2-4,11-16,19-20H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound against acetylcholinesterase(AChE) from rat brain was determined				Bioorg Med Chem Lett 4: 615-618 (1994) Article DOI: 10.1016/S0960-894X(01)80165-7 BindingDB Entry DOI: 10.7270/Q2FN1659
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50022775 ((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...) Show SMILES CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C Show InChI InChI=1S/C12H19N2O2/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5/h6-9H,1-5H3/q+1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig acetylcholinesterase				J Med Chem 36: 572-9 (1993) BindingDB Entry DOI: 10.7270/Q2930TSP
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50237878 (2-(1,3-bis(3-(piperidin-1-yl)propyl)imidazolidin-2...) Show SMILES N#C\[#6](C#N)=[#6]-1\[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C22H36N6/c23-19-21(20-24)22-27(15-7-13-25-9-3-1-4-10-25)17-18-28(22)16-8-14-26-11-5-2-6-12-26/h1-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Antagonist activity at histamine H3 receptor in rat forebrain assessed as inhibition of [3H]histamine release from synaptosomes				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50047730 (2-(1-{2-[(5-Piperidin-1-ylmethyl-furan-2-ylmethyl)...) Show SMILES N#CC(C#N)C1=NCCN1CCNCc1ccc(CN2CCCCC2)o1 |t:5| Show InChI InChI=1S/C19H26N6O/c20-12-16(13-21)19-23-7-11-25(19)10-6-22-14-17-4-5-18(26-17)15-24-8-2-1-3-9-24/h4-5,16,22H,1-3,6-11,14-15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound against acetylcholinesterase(AChE) from rat brain was determined				Bioorg Med Chem Lett 4: 615-618 (1994) Article DOI: 10.1016/S0960-894X(01)80165-7 BindingDB Entry DOI: 10.7270/Q2FN1659
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50047730 (2-(1-{2-[(5-Piperidin-1-ylmethyl-furan-2-ylmethyl)...) Show SMILES N#CC(C#N)C1=NCCN1CCNCc1ccc(CN2CCCCC2)o1 |t:5| Show InChI InChI=1S/C19H26N6O/c20-12-16(13-21)19-23-7-11-25(19)10-6-22-14-17-4-5-18(26-17)15-24-8-2-1-3-9-24/h4-5,16,22H,1-3,6-11,14-15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig acetylcholinesterase				J Med Chem 36: 572-9 (1993) BindingDB Entry DOI: 10.7270/Q2930TSP
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50284038 (2-(1-(2-Methoxy-phenyl)-3-{2-[(5-piperidin-1-ylmet...) Show SMILES [#6]-[#8]-c1ccccc1-[#7]1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-[#6]-c2ccc(-[#6]-[#7]-3-[#6]-[#6]-[#6]-[#6]-[#6]-3)o2)\[#6]-1=[#6](\C#N)C#N Show InChI InChI=1S/C26H32N6O2/c1-33-25-8-4-3-7-24(25)32-16-15-31(26(32)21(17-27)18-28)14-11-29-19-22-9-10-23(34-22)20-30-12-5-2-6-13-30/h3-4,7-10,29H,2,5-6,11-16,19-20H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound against acetylcholinesterase(AChE) from rat brain was determined				Bioorg Med Chem Lett 4: 615-618 (1994) Article DOI: 10.1016/S0960-894X(01)80165-7 BindingDB Entry DOI: 10.7270/Q2FN1659
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50047736 (2-(1-{2-[(5-Piperidin-1-ylmethyl-furan-2-ylmethyl)...) Show SMILES N#CC(C#N)c1nc2ccccc2n1CCNCc1ccc(CN2CCCCC2)o1 Show InChI InChI=1S/C23H26N6O/c24-14-18(15-25)23-27-21-6-2-3-7-22(21)29(23)13-10-26-16-19-8-9-20(30-19)17-28-11-4-1-5-12-28/h2-3,6-9,18,26H,1,4-5,10-13,16-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig acetylcholinesterase				J Med Chem 36: 572-9 (1993) BindingDB Entry DOI: 10.7270/Q2930TSP
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50047745 (2-(1-{2-[(5-Pyrrolidin-1-ylmethyl-furan-2-ylmethyl...) Show SMILES N#CC(C#N)C1=NCCN1CCNCc1ccc(CN2CCCC2)o1 |t:5| Show InChI InChI=1S/C18H24N6O/c19-11-15(12-20)18-22-6-10-24(18)9-5-21-13-16-3-4-17(25-16)14-23-7-1-2-8-23/h3-4,15,21H,1-2,5-10,13-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig acetylcholinesterase				J Med Chem 36: 572-9 (1993) BindingDB Entry DOI: 10.7270/Q2930TSP
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50368819 (CHEMBL1203534) Show SMILES N#CC(C#N)C1=NCCN1CCNCc1ccc(CN2CCC=CC2)o1 |c:23,t:5| Show InChI InChI=1S/C19H24N6O/c20-12-16(13-21)19-23-7-11-25(19)10-6-22-14-17-4-5-18(26-17)15-24-8-2-1-3-9-24/h1-2,4-5,16,22H,3,6-11,14-15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig acetylcholinesterase				J Med Chem 36: 572-9 (1993) BindingDB Entry DOI: 10.7270/Q2930TSP
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50368820 (CHEMBL1203538) Show SMILES N#CC(C#N)C1=NCCN1CCNCc1ccc(CN2CCCCCC2)o1 |t:5| Show InChI InChI=1S/C20H28N6O/c21-13-17(14-22)20-24-8-12-26(20)11-7-23-15-18-5-6-19(27-18)16-25-9-3-1-2-4-10-25/h5-6,17,23H,1-4,7-12,15-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig acetylcholinesterase				J Med Chem 36: 572-9 (1993) BindingDB Entry DOI: 10.7270/Q2930TSP
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50047751 (2-(Methylamino-{2-[(5-pyrrolidin-1-ylmethyl-furan-...) Show SMILES CN=C(NCCNCc1ccc(CN2CCCC2)o1)C(C#N)C#N |w:1.0| Show InChI InChI=1S/C17H24N6O/c1-20-17(14(10-18)11-19)22-7-6-21-12-15-4-5-16(24-15)13-23-8-2-3-9-23/h4-5,14,21H,2-3,6-9,12-13H2,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig acetylcholinesterase				J Med Chem 36: 572-9 (1993) BindingDB Entry DOI: 10.7270/Q2930TSP
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50047747 (2-[1-(2-{[5-(4-Methyl-piperidin-1-ylmethyl)-furan-...) Show SMILES CC1CCN(Cc2ccc(CNCCN3CCN=C3C(C#N)C#N)o2)CC1 |c:17| Show InChI InChI=1S/C20H28N6O/c1-16-4-8-25(9-5-16)15-19-3-2-18(27-19)14-23-6-10-26-11-7-24-20(26)17(12-21)13-22/h2-3,16-17,23H,4-11,14-15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig acetylcholinesterase				J Med Chem 36: 572-9 (1993) BindingDB Entry DOI: 10.7270/Q2930TSP
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50047731 (2-[1-(2-{[5-(3-Hydroxy-piperidin-1-ylmethyl)-furan...) Show SMILES OC1CCCN(Cc2ccc(CNCCN3CCN=C3C(C#N)C#N)o2)C1 |c:18| Show InChI InChI=1S/C19H26N6O2/c20-10-15(11-21)19-23-6-9-25(19)8-5-22-12-17-3-4-18(27-17)14-24-7-1-2-16(26)13-24/h3-4,15-16,22,26H,1-2,5-9,12-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig acetylcholinesterase				J Med Chem 36: 572-9 (1993) BindingDB Entry DOI: 10.7270/Q2930TSP
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50047742 (2-[1-(2-{[5-(3-Methyl-piperidin-1-ylmethyl)-furan-...) Show SMILES CC1CCCN(Cc2ccc(CNCCN3CCN=C3C(C#N)C#N)o2)C1 |c:18| Show InChI InChI=1S/C20H28N6O/c1-16-3-2-8-25(14-16)15-19-5-4-18(27-19)13-23-6-9-26-10-7-24-20(26)17(11-21)12-22/h4-5,16-17,23H,2-3,6-10,13-15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig acetylcholinesterase				J Med Chem 36: 572-9 (1993) BindingDB Entry DOI: 10.7270/Q2930TSP
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50047753 (2-(1-{2-[(5-Dimethylaminomethyl-furan-2-ylmethyl)-...) Show SMILES CN(C)Cc1ccc(CNCCN2CCN=C2C(C#N)C#N)o1 |c:15| Show InChI InChI=1S/C16H22N6O/c1-21(2)12-15-4-3-14(23-15)11-19-5-7-22-8-6-20-16(22)13(9-17)10-18/h3-4,13,19H,5-8,11-12H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig acetylcholinesterase				J Med Chem 36: 572-9 (1993) BindingDB Entry DOI: 10.7270/Q2930TSP
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50047741 (2-[1-(2-{[5-(4-Hydroxy-piperidin-1-ylmethyl)-furan...) Show SMILES OC1CCN(Cc2ccc(CNCCN3CCN=C3C(C#N)C#N)o2)CC1 |c:17| Show InChI InChI=1S/C19H26N6O2/c20-11-15(12-21)19-23-6-10-25(19)9-5-22-13-17-1-2-18(27-17)14-24-7-3-16(26)4-8-24/h1-2,15-16,22,26H,3-10,13-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig acetylcholinesterase				J Med Chem 36: 572-9 (1993) BindingDB Entry DOI: 10.7270/Q2930TSP
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50047752 (2-{1-[2-({5-[(Ethyl-methyl-amino)-methyl]-furan-2-...) Show SMILES CCN(C)Cc1ccc(CNCCN2CCN=C2C(C#N)C#N)o1 |c:16| Show InChI InChI=1S/C17H24N6O/c1-3-22(2)13-16-5-4-15(24-16)12-20-6-8-23-9-7-21-17(23)14(10-18)11-19/h4-5,14,20H,3,6-9,12-13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig acetylcholinesterase				J Med Chem 36: 572-9 (1993) BindingDB Entry DOI: 10.7270/Q2930TSP
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50047754 (2-[1-(2-{[5-(2-Methyl-piperidin-1-ylmethyl)-furan-...) Show SMILES CC1CCCCN1Cc1ccc(CNCCN2CCN=C2C(C#N)C#N)o1 |c:20| Show InChI InChI=1S/C20H28N6O/c1-16-4-2-3-9-26(16)15-19-6-5-18(27-19)14-23-7-10-25-11-8-24-20(25)17(12-21)13-22/h5-6,16-17,23H,2-4,7-11,14-15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig acetylcholinesterase				J Med Chem 36: 572-9 (1993) BindingDB Entry DOI: 10.7270/Q2930TSP
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50368818 (CHEMBL1203539) Show SMILES CCN(CC)Cc1ccc(CNCCN2CCN=C2C(C#N)C#N)o1 |c:17| Show InChI InChI=1S/C18H26N6O/c1-3-23(4-2)14-17-6-5-16(25-17)13-21-7-9-24-10-8-22-18(24)15(11-19)12-20/h5-6,15,21H,3-4,7-10,13-14H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig acetylcholinesterase				J Med Chem 36: 572-9 (1993) BindingDB Entry DOI: 10.7270/Q2930TSP
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50047749 (2-({2-[(5-Dimethylaminomethyl-furan-2-ylmethyl)-am...) Show SMILES CN=C(NCCNCc1ccc(CN(C)C)o1)C(C#N)C#N |w:1.0| Show InChI InChI=1S/C15H22N6O/c1-18-15(12(8-16)9-17)20-7-6-19-10-13-4-5-14(22-13)11-21(2)3/h4-5,12,19H,6-7,10-11H2,1-3H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig acetylcholinesterase				J Med Chem 36: 572-9 (1993) BindingDB Entry DOI: 10.7270/Q2930TSP
					More data for this Ligand-Target Pair

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