Found 158 hits with Last Name = 'schrey' and Initial = 'ak' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209698
(1-(3'-cyano-4-biphenylmethyl)-3-(2-hydroxy-1,1-dim...)Show SMILES Cc1ccc(CN2CCC(CCN(Cc3ccc(cc3)-c3cccc(c3)C#N)C(=O)NC(C)(C)CO)CC2)cc1 Show InChI InChI=1S/C34H42N4O2/c1-26-7-9-28(10-8-26)23-37-18-15-27(16-19-37)17-20-38(33(40)36-34(2,3)25-39)24-29-11-13-31(14-12-29)32-6-4-5-30(21-32)22-35/h4-14,21,27,39H,15-20,23-25H2,1-3H3,(H,36,40) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209691
(1-(4'-fluoro-4-biphenylmethyl)-3-(2-hydroxy-1,1-di...)Show SMILES Cc1ccc(CN2CCC(CCN(Cc3ccc(cc3)-c3ccc(F)cc3)C(=O)NC(C)(C)CO)CC2)cc1 Show InChI InChI=1S/C33H42FN3O2/c1-25-4-6-27(7-5-25)22-36-19-16-26(17-20-36)18-21-37(32(39)35-33(2,3)24-38)23-28-8-10-29(11-9-28)30-12-14-31(34)15-13-30/h4-15,26,38H,16-24H2,1-3H3,(H,35,39) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 96.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209692
(3-[1,1-di(hydroxymethyl)propyl]-1-(4'-methoxy-4-bi...)Show SMILES CCC(CO)(CO)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccc(OC)cc1 Show InChI InChI=1S/C35H47N3O4/c1-4-35(25-39,26-40)36-34(41)38(24-30-9-11-31(12-10-30)32-13-15-33(42-3)16-14-32)22-19-28-17-20-37(21-18-28)23-29-7-5-27(2)6-8-29/h5-16,28,39-40H,4,17-26H2,1-3H3,(H,36,41) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 143 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209693
(1-(4-biphenylmethyl)-3-(2-hydroxy-1,1-dimethylethy...)Show SMILES Cc1ccc(CN2CCC(CCN(Cc3ccc(cc3)-c3ccccc3)C(=O)NC(C)(C)CO)CC2)cc1 Show InChI InChI=1S/C33H43N3O2/c1-26-9-11-28(12-10-26)23-35-20-17-27(18-21-35)19-22-36(32(38)34-33(2,3)25-37)24-29-13-15-31(16-14-29)30-7-5-4-6-8-30/h4-16,27,37H,17-25H2,1-3H3,(H,34,38) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 144 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209709
(1-(4'-fluoro-4-biphenylmethyl)-3-(1,1-di(hydroxyme...)Show SMILES CCC(CO)(CO)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H44FN3O3/c1-3-34(24-39,25-40)36-33(41)38(23-29-8-10-30(11-9-29)31-12-14-32(35)15-13-31)21-18-27-16-19-37(20-17-27)22-28-6-4-26(2)5-7-28/h4-15,27,39-40H,3,16-25H2,1-2H3,(H,36,41) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 149 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209713
(3-[1,1-di(hydroxymethyl)propyl]-1-(2'-methoxy-4-bi...)Show SMILES CCC(CO)(CO)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccccc1OC Show InChI InChI=1S/C35H47N3O4/c1-4-35(25-39,26-40)36-34(41)38(24-30-13-15-31(16-14-30)32-7-5-6-8-33(32)42-3)22-19-28-17-20-37(21-18-28)23-29-11-9-27(2)10-12-29/h5-16,28,39-40H,4,17-26H2,1-3H3,(H,36,41) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 167 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209699
(3-[1,1-di(acetyloxymethyl)propyl]-1-(4'-methoxy-4-...)Show SMILES CCC(COC(C)=O)(COC(C)=O)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccc(OC)cc1 Show InChI InChI=1S/C39H51N3O6/c1-6-39(27-47-30(3)43,28-48-31(4)44)40-38(45)42(26-34-11-13-35(14-12-34)36-15-17-37(46-5)18-16-36)24-21-32-19-22-41(23-20-32)25-33-9-7-29(2)8-10-33/h7-18,32H,6,19-28H2,1-5H3,(H,40,45) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209690
(1-(4-biphenylmethyl)-3-[1,1-di(hydroxymethyl)propy...)Show SMILES CCC(CO)(CO)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C34H45N3O3/c1-3-34(25-38,26-39)35-33(40)37(24-30-13-15-32(16-14-30)31-7-5-4-6-8-31)22-19-28-17-20-36(21-18-28)23-29-11-9-27(2)10-12-29/h4-16,28,38-39H,3,17-26H2,1-2H3,(H,35,40) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 173 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209687
(1-(3'-cyano-4-biphenylmethyl)-3-[1-(4-methylbenzyl...)Show SMILES Cc1ccc(CN2CCC(CC2)NC(=O)NCc2ccc(cc2)-c2cccc(c2)C#N)cc1 Show InChI InChI=1S/C28H30N4O/c1-21-5-7-23(8-6-21)20-32-15-13-27(14-16-32)31-28(33)30-19-22-9-11-25(12-10-22)26-4-2-3-24(17-26)18-29/h2-12,17,27H,13-16,19-20H2,1H3,(H2,30,31,33) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 186 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209711
(3-(2-hydroxy-1,1-dimethylethyl)-1-(4'-methoxy-4-bi...)Show SMILES COc1ccc(cc1)-c1ccc(CN(CCC2CCN(Cc3ccc(C)cc3)CC2)C(=O)NC(C)(C)CO)cc1 Show InChI InChI=1S/C34H45N3O3/c1-26-5-7-28(8-6-26)23-36-20-17-27(18-21-36)19-22-37(33(39)35-34(2,3)25-38)24-29-9-11-30(12-10-29)31-13-15-32(40-4)16-14-31/h5-16,27,38H,17-25H2,1-4H3,(H,35,39) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 204 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209688
(3-[1,1-di(acetyloxymethyl)propyl]-1-(4'-fluoro-4-b...)Show SMILES CCC(COC(C)=O)(COC(C)=O)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C38H48FN3O5/c1-5-38(26-46-29(3)43,27-47-30(4)44)40-37(45)42(25-33-10-12-34(13-11-33)35-14-16-36(39)17-15-35)23-20-31-18-21-41(22-19-31)24-32-8-6-28(2)7-9-32/h6-17,31H,5,18-27H2,1-4H3,(H,40,45) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 214 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209689
(3-[1-(acetyloxymethyl)-1-methylethyl]-1-(2'-methox...)Show SMILES COc1ccccc1-c1ccc(CN(CCC2CCN(Cc3ccc(C)cc3)CC2)C(=O)NC(C)(C)COC(C)=O)cc1 Show InChI InChI=1S/C36H47N3O4/c1-27-10-12-30(13-11-27)24-38-21-18-29(19-22-38)20-23-39(35(41)37-36(3,4)26-43-28(2)40)25-31-14-16-32(17-15-31)33-8-6-7-9-34(33)42-5/h6-17,29H,18-26H2,1-5H3,(H,37,41) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 215 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209717
(3-(2-hydroxy-1,1-dimethylethyl)-1-(2'-methoxy-4-bi...)Show SMILES COc1ccccc1-c1ccc(CN(CCC2CCN(Cc3ccc(C)cc3)CC2)C(=O)NC(C)(C)CO)cc1 Show InChI InChI=1S/C34H45N3O3/c1-26-9-11-28(12-10-26)23-36-20-17-27(18-21-36)19-22-37(33(39)35-34(2,3)25-38)24-29-13-15-30(16-14-29)31-7-5-6-8-32(31)40-4/h5-16,27,38H,17-25H2,1-4H3,(H,35,39) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209714
(3-[1-(acetyloxymethyl)-1-methylethyl]-1-(3'-cyano-...)Show SMILES CC(=O)OCC(C)(C)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1cccc(c1)C#N Show InChI InChI=1S/C36H44N4O3/c1-27-8-10-30(11-9-27)24-39-19-16-29(17-20-39)18-21-40(35(42)38-36(3,4)26-43-28(2)41)25-31-12-14-33(15-13-31)34-7-5-6-32(22-34)23-37/h5-15,22,29H,16-21,24-26H2,1-4H3,(H,38,42) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 254 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209707
(1-(4-biphenylmethyl)-3-isopropyl-1-{2-[1-(4-methyl...)Show SMILES CC(C)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C32H41N3O/c1-25(2)33-32(36)35(24-29-13-15-31(16-14-29)30-7-5-4-6-8-30)22-19-27-17-20-34(21-18-27)23-28-11-9-26(3)10-12-28/h4-16,25,27H,17-24H2,1-3H3,(H,33,36) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 258 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209715
(3-isopropyl-1-(4'-methoxy-4-biphenylmethyl)-1-{2-[...)Show SMILES COc1ccc(cc1)-c1ccc(CN(CCC2CCN(Cc3ccc(C)cc3)CC2)C(=O)NC(C)C)cc1 Show InChI InChI=1S/C33H43N3O2/c1-25(2)34-33(37)36(24-29-9-11-30(12-10-29)31-13-15-32(38-4)16-14-31)22-19-27-17-20-35(21-18-27)23-28-7-5-26(3)6-8-28/h5-16,25,27H,17-24H2,1-4H3,(H,34,37) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 273 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209704
(1-(4'-fluoro-4-biphenylmethyl)-3-isopropyl-1-{2-[1...)Show SMILES CC(C)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H40FN3O/c1-24(2)34-32(37)36(23-28-8-10-29(11-9-28)30-12-14-31(33)15-13-30)21-18-26-16-19-35(20-17-26)22-27-6-4-25(3)5-7-27/h4-15,24,26H,16-23H2,1-3H3,(H,34,37) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 314 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209706
(3-[1,1-di(acetyloxymethyl)propyl]-1-(4-biphenylmet...)Show SMILES CCC(COC(C)=O)(COC(C)=O)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C38H49N3O5/c1-5-38(27-45-30(3)42,28-46-31(4)43)39-37(44)41(26-34-15-17-36(18-16-34)35-9-7-6-8-10-35)24-21-32-19-22-40(23-20-32)25-33-13-11-29(2)12-14-33/h6-18,32H,5,19-28H2,1-4H3,(H,39,44) | Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 388 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209700
(3-[1-(acetyloxymethyl)-1-methylethyl]-1-(4'-fluoro...)Show SMILES CC(=O)OCC(C)(C)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C35H44FN3O3/c1-26-5-7-29(8-6-26)23-38-20-17-28(18-21-38)19-22-39(34(41)37-35(3,4)25-42-27(2)40)24-30-9-11-31(12-10-30)32-13-15-33(36)16-14-32/h5-16,28H,17-25H2,1-4H3,(H,37,41) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 421 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209705
(1-(2'-methoxy-4-biphenylmethyl)-3-[1-(4-methylbenz...)Show SMILES COc1ccccc1-c1ccc(CNC(=O)NC2CCN(Cc3ccc(C)cc3)CC2)cc1 Show InChI InChI=1S/C28H33N3O2/c1-21-7-9-23(10-8-21)20-31-17-15-25(16-18-31)30-28(32)29-19-22-11-13-24(14-12-22)26-5-3-4-6-27(26)33-2/h3-14,25H,15-20H2,1-2H3,(H2,29,30,32) | Reactome pathway
KEGG
UniProtKB/SwissProt
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 425 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209702
(1-(3'-cyano-4-biphenylmethyl)-3-isopropyl-1-{2-[1-...)Show SMILES CC(C)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1cccc(c1)C#N Show InChI InChI=1S/C33H40N4O/c1-25(2)35-33(38)37(24-29-11-13-31(14-12-29)32-6-4-5-30(21-32)22-34)20-17-27-15-18-36(19-16-27)23-28-9-7-26(3)8-10-28/h4-14,21,25,27H,15-20,23-24H2,1-3H3,(H,35,38) | Reactome pathway
KEGG
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PC sid
UniChem
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PubMed
| 509 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209694
(1-(4'-fluoro-4-biphenylmethyl)-3-[1-(4-methylbenzy...)Show SMILES Cc1ccc(CN2CCC(CC2)NC(=O)NCc2ccc(cc2)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C27H30FN3O/c1-20-2-4-22(5-3-20)19-31-16-14-26(15-17-31)30-27(32)29-18-21-6-8-23(9-7-21)24-10-12-25(28)13-11-24/h2-13,26H,14-19H2,1H3,(H2,29,30,32) | Reactome pathway
KEGG
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PC sid
UniChem
Similars
| Article
PubMed
| 545 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50209688
(3-[1,1-di(acetyloxymethyl)propyl]-1-(4'-fluoro-4-b...)Show SMILES CCC(COC(C)=O)(COC(C)=O)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C38H48FN3O5/c1-5-38(26-46-29(3)43,27-47-30(4)44)40-37(45)42(25-33-10-12-34(13-11-33)35-14-16-36(39)17-15-35)23-20-31-18-21-41(22-19-31)24-32-8-6-28(2)7-9-32/h6-17,31H,5,18-27H2,1-4H3,(H,40,45) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 548 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50329936
(1-(3-hydroxy-3-methyl-2-oxobutyl)-1-((4'-methoxybi...)Show SMILES COc1ccc(cc1)-c1ccc(CN(CC(=O)C(C)(C)O)C(=O)NC2CCN(Cc3ccc(C)cc3)CC2)cc1 Show InChI InChI=1S/C33H41N3O4/c1-24-5-7-25(8-6-24)21-35-19-17-29(18-20-35)34-32(38)36(23-31(37)33(2,3)39)22-26-9-11-27(12-10-26)28-13-15-30(40-4)16-14-28/h5-16,29,39H,17-23H2,1-4H3,(H,34,38) | PDB
Reactome pathway
KEGG
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 581 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209708
(3-[1-(acetyloxymethyl)-1-methylethyl]-1-(4'-methox...)Show SMILES COc1ccc(cc1)-c1ccc(CN(CCC2CCN(Cc3ccc(C)cc3)CC2)C(=O)NC(C)(C)COC(C)=O)cc1 Show InChI InChI=1S/C36H47N3O4/c1-27-6-8-30(9-7-27)24-38-21-18-29(19-22-38)20-23-39(35(41)37-36(3,4)26-43-28(2)40)25-31-10-12-32(13-11-31)33-14-16-34(42-5)17-15-33/h6-17,29H,18-26H2,1-5H3,(H,37,41) | Reactome pathway
KEGG
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 595 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50209701
(3-[1,1-di(acetyloxymethyl)propyl]-1-(2'-methoxy-4-...)Show SMILES CCC(COC(C)=O)(COC(C)=O)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccccc1OC Show InChI InChI=1S/C39H51N3O6/c1-6-39(27-47-30(3)43,28-48-31(4)44)40-38(45)42(26-34-15-17-35(18-16-34)36-9-7-8-10-37(36)46-5)24-21-32-19-22-41(23-20-32)25-33-13-11-29(2)12-14-33/h7-18,32H,6,19-28H2,1-5H3,(H,40,45) | PDB
Reactome pathway
KEGG
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 629 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209712
(1-(3'-cyano-4-biphenylmethyl)-3-[1,1-di(hydroxymet...)Show SMILES CCC(CO)(CO)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1cccc(c1)C#N Show InChI InChI=1S/C35H44N4O3/c1-3-35(25-40,26-41)37-34(42)39(24-30-11-13-32(14-12-30)33-6-4-5-31(21-33)22-36)20-17-28-15-18-38(19-16-28)23-29-9-7-27(2)8-10-29/h4-14,21,28,40-41H,3,15-20,23-26H2,1-2H3,(H,37,42) | Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 769 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50209699
(3-[1,1-di(acetyloxymethyl)propyl]-1-(4'-methoxy-4-...)Show SMILES CCC(COC(C)=O)(COC(C)=O)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccc(OC)cc1 Show InChI InChI=1S/C39H51N3O6/c1-6-39(27-47-30(3)43,28-48-31(4)44)40-38(45)42(26-34-11-13-35(14-12-34)36-15-17-37(46-5)18-16-36)24-21-32-19-22-41(23-20-32)25-33-9-7-29(2)8-10-33/h7-18,32H,6,19-28H2,1-5H3,(H,40,45) | PDB
Reactome pathway
KEGG
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antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 779 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50209706
(3-[1,1-di(acetyloxymethyl)propyl]-1-(4-biphenylmet...)Show SMILES CCC(COC(C)=O)(COC(C)=O)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C38H49N3O5/c1-5-38(27-45-30(3)42,28-46-31(4)43)39-37(44)41(26-34-15-17-36(18-16-34)35-9-7-6-8-10-35)24-21-32-19-22-40(23-20-32)25-33-13-11-29(2)12-14-33/h6-18,32H,5,19-28H2,1-4H3,(H,39,44) | PDB
Reactome pathway
KEGG
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antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 807 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50209702
(1-(3'-cyano-4-biphenylmethyl)-3-isopropyl-1-{2-[1-...)Show SMILES CC(C)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1cccc(c1)C#N Show InChI InChI=1S/C33H40N4O/c1-25(2)35-33(38)37(24-29-11-13-31(14-12-29)32-6-4-5-30(21-32)22-34)20-17-27-15-18-36(19-16-27)23-28-9-7-26(3)8-10-28/h4-14,21,25,27H,15-20,23-24H2,1-3H3,(H,35,38) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 853 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50209692
(3-[1,1-di(hydroxymethyl)propyl]-1-(4'-methoxy-4-bi...)Show SMILES CCC(CO)(CO)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccc(OC)cc1 Show InChI InChI=1S/C35H47N3O4/c1-4-35(25-39,26-40)36-34(41)38(24-30-9-11-31(12-10-30)32-13-15-33(42-3)16-14-32)22-19-28-17-20-37(21-18-28)23-29-7-5-27(2)6-8-29/h5-16,28,39-40H,4,17-26H2,1-3H3,(H,36,41) | PDB
Reactome pathway
KEGG
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antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 899 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50403047
(CHEMBL1231568)Show SMILES CCOC(=O)CCN(C(=O)c1ccc2n(C)c(CNc3ccc(cc3)C(N)=N)nc2c1)c1ccccn1 Show InChI InChI=1S/C27H29N7O3/c1-3-37-25(35)13-15-34(23-6-4-5-14-30-23)27(36)19-9-12-22-21(16-19)32-24(33(22)2)17-31-20-10-7-18(8-11-20)26(28)29/h4-12,14,16,31H,3,13,15,17H2,1-2H3,(H3,28,29) | PDB
MMDB
KEGG
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| Purchase
CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
caprotec bioanalytics GmbH
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant NQO2-mediated mitomycin C metabolism using NADH as cosubstrate incubated for 5 mins prior to NADH addition measured a... |
J Med Chem 55: 3934-44 (2012)
Article DOI: 10.1021/jm3001339
BindingDB Entry DOI: 10.7270/Q25T3MNJ |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209695
(3-[1-(acetyloxymethyl)-1-methylethyl]-1-(4-bipheny...)Show SMILES CC(=O)OCC(C)(C)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C35H45N3O3/c1-27-10-12-30(13-11-27)24-37-21-18-29(19-22-37)20-23-38(34(40)36-35(3,4)26-41-28(2)39)25-31-14-16-33(17-15-31)32-8-6-5-7-9-32/h5-17,29H,18-26H2,1-4H3,(H,36,40) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 947 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50209705
(1-(2'-methoxy-4-biphenylmethyl)-3-[1-(4-methylbenz...)Show SMILES COc1ccccc1-c1ccc(CNC(=O)NC2CCN(Cc3ccc(C)cc3)CC2)cc1 Show InChI InChI=1S/C28H33N3O2/c1-21-7-9-23(10-8-21)20-31-17-15-25(16-18-31)30-28(32)29-19-22-11-13-24(14-12-22)26-5-3-4-6-27(26)33-2/h3-14,25H,15-20H2,1-2H3,(H2,29,30,32) | PDB
Reactome pathway
KEGG
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antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50209709
(1-(4'-fluoro-4-biphenylmethyl)-3-(1,1-di(hydroxyme...)Show SMILES CCC(CO)(CO)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H44FN3O3/c1-3-34(24-39,25-40)36-33(41)38(23-29-8-10-30(11-9-29)31-12-14-32(35)15-13-31)21-18-27-16-19-37(20-17-27)22-28-6-4-26(2)5-7-28/h4-15,27,39-40H,3,16-25H2,1-2H3,(H,36,41) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50209691
(1-(4'-fluoro-4-biphenylmethyl)-3-(2-hydroxy-1,1-di...)Show SMILES Cc1ccc(CN2CCC(CCN(Cc3ccc(cc3)-c3ccc(F)cc3)C(=O)NC(C)(C)CO)CC2)cc1 Show InChI InChI=1S/C33H42FN3O2/c1-25-4-6-27(7-5-25)22-36-19-16-26(17-20-36)18-21-37(32(39)35-33(2,3)24-38)23-28-8-10-29(11-9-28)30-12-14-31(34)15-13-30/h4-15,26,38H,16-24H2,1-3H3,(H,35,39) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50209687
(1-(3'-cyano-4-biphenylmethyl)-3-[1-(4-methylbenzyl...)Show SMILES Cc1ccc(CN2CCC(CC2)NC(=O)NCc2ccc(cc2)-c2cccc(c2)C#N)cc1 Show InChI InChI=1S/C28H30N4O/c1-21-5-7-23(8-6-21)20-32-15-13-27(14-16-32)31-28(33)30-19-22-9-11-25(12-10-22)26-4-2-3-24(17-26)18-29/h2-12,17,27H,13-16,19-20H2,1H3,(H2,30,31,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50209696
(1-(4-biphenylmethyl)-3-[1-(4-methylbenzyl)-4-piper...)Show SMILES Cc1ccc(CN2CCC(CC2)NC(=O)NCc2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C27H31N3O/c1-21-7-9-23(10-8-21)20-30-17-15-26(16-18-30)29-27(31)28-19-22-11-13-25(14-12-22)24-5-3-2-4-6-24/h2-14,26H,15-20H2,1H3,(H2,28,29,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50329938
(3-isopropyl-1-((2'-methoxybiphenyl-4-yl)methyl)-1-...)Show SMILES COc1ccccc1-c1ccc(CN(CCC2CCN(Cc3ccc(C)cc3)CC2)C(=O)NC(C)C)cc1 Show InChI InChI=1S/C33H43N3O2/c1-25(2)34-33(37)36(24-29-13-15-30(16-14-29)31-7-5-6-8-32(31)38-4)22-19-27-17-20-35(21-18-27)23-28-11-9-26(3)10-12-28/h5-16,25,27H,17-24H2,1-4H3,(H,34,37) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50209707
(1-(4-biphenylmethyl)-3-isopropyl-1-{2-[1-(4-methyl...)Show SMILES CC(C)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C32H41N3O/c1-25(2)33-32(36)35(24-29-13-15-31(16-14-29)30-7-5-4-6-8-30)22-19-27-17-20-34(21-18-27)23-28-11-9-26(3)10-12-28/h4-16,25,27H,17-24H2,1-3H3,(H,33,36) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50329936
(1-(3-hydroxy-3-methyl-2-oxobutyl)-1-((4'-methoxybi...)Show SMILES COc1ccc(cc1)-c1ccc(CN(CC(=O)C(C)(C)O)C(=O)NC2CCN(Cc3ccc(C)cc3)CC2)cc1 Show InChI InChI=1S/C33H41N3O4/c1-24-5-7-25(8-6-24)21-35-19-17-29(18-20-35)34-32(38)36(23-31(37)33(2,3)39)22-26-9-11-27(12-10-26)28-13-15-30(40-4)16-14-28/h5-16,29,39H,17-23H2,1-4H3,(H,34,38) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50329938
(3-isopropyl-1-((2'-methoxybiphenyl-4-yl)methyl)-1-...)Show SMILES COc1ccccc1-c1ccc(CN(CCC2CCN(Cc3ccc(C)cc3)CC2)C(=O)NC(C)C)cc1 Show InChI InChI=1S/C33H43N3O2/c1-25(2)34-33(37)36(24-29-13-15-30(16-14-29)31-7-5-6-8-32(31)38-4)22-19-27-17-20-35(21-18-27)23-28-11-9-26(3)10-12-28/h5-16,25,27H,17-24H2,1-4H3,(H,34,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50329937
(1-(4-biphenylmethyl)-1-(3-hydroxy-3-methyl-2-oxobu...)Show SMILES Cc1ccc(CN2CCC(CC2)NC(=O)N(CC(=O)C(C)(C)O)Cc2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C32H39N3O3/c1-24-9-11-25(12-10-24)21-34-19-17-29(18-20-34)33-31(37)35(23-30(36)32(2,3)38)22-26-13-15-28(16-14-26)27-7-5-4-6-8-27/h4-16,29,38H,17-23H2,1-3H3,(H,33,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50329937
(1-(4-biphenylmethyl)-1-(3-hydroxy-3-methyl-2-oxobu...)Show SMILES Cc1ccc(CN2CCC(CC2)NC(=O)N(CC(=O)C(C)(C)O)Cc2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C32H39N3O3/c1-24-9-11-25(12-10-24)21-34-19-17-29(18-20-34)33-31(37)35(23-30(36)32(2,3)38)22-26-13-15-28(16-14-26)27-7-5-4-6-8-27/h4-16,29,38H,17-23H2,1-3H3,(H,33,37) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50209708
(3-[1-(acetyloxymethyl)-1-methylethyl]-1-(4'-methox...)Show SMILES COc1ccc(cc1)-c1ccc(CN(CCC2CCN(Cc3ccc(C)cc3)CC2)C(=O)NC(C)(C)COC(C)=O)cc1 Show InChI InChI=1S/C36H47N3O4/c1-27-6-8-30(9-7-27)24-38-21-18-29(19-22-38)20-23-39(35(41)37-36(3,4)26-43-28(2)40)25-31-10-12-32(13-11-31)33-14-16-34(42-5)17-15-33/h6-17,29H,18-26H2,1-5H3,(H,37,41) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50209689
(3-[1-(acetyloxymethyl)-1-methylethyl]-1-(2'-methox...)Show SMILES COc1ccccc1-c1ccc(CN(CCC2CCN(Cc3ccc(C)cc3)CC2)C(=O)NC(C)(C)COC(C)=O)cc1 Show InChI InChI=1S/C36H47N3O4/c1-27-10-12-30(13-11-27)24-38-21-18-29(19-22-38)20-23-39(35(41)37-36(3,4)26-43-28(2)40)25-31-14-16-32(17-15-31)33-8-6-7-9-34(33)42-5/h6-17,29H,18-26H2,1-5H3,(H,37,41) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209710
(3-[1,1-di(acetyloxymethyl)propyl]-1-(3'-cyano-4-bi...)Show SMILES CCC(COC(C)=O)(COC(C)=O)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1cccc(c1)C#N Show InChI InChI=1S/C39H48N4O5/c1-5-39(27-47-30(3)44,28-48-31(4)45)41-38(46)43(26-34-13-15-36(16-14-34)37-8-6-7-35(23-37)24-40)22-19-32-17-20-42(21-18-32)25-33-11-9-29(2)10-12-33/h6-16,23,32H,5,17-22,25-28H2,1-4H3,(H,41,46) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50209695
(3-[1-(acetyloxymethyl)-1-methylethyl]-1-(4-bipheny...)Show SMILES CC(=O)OCC(C)(C)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C35H45N3O3/c1-27-10-12-30(13-11-27)24-37-21-18-29(19-22-37)20-23-38(34(40)36-35(3,4)26-41-28(2)39)25-31-14-16-33(17-15-31)32-8-6-5-7-9-32/h5-17,29H,18-26H2,1-4H3,(H,36,40) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50209698
(1-(3'-cyano-4-biphenylmethyl)-3-(2-hydroxy-1,1-dim...)Show SMILES Cc1ccc(CN2CCC(CCN(Cc3ccc(cc3)-c3cccc(c3)C#N)C(=O)NC(C)(C)CO)CC2)cc1 Show InChI InChI=1S/C34H42N4O2/c1-26-7-9-28(10-8-26)23-37-18-15-27(16-19-37)17-20-38(33(40)36-34(2,3)25-39)24-29-11-13-31(14-12-29)32-6-4-5-30(21-32)22-35/h4-14,21,27,39H,15-20,23-25H2,1-3H3,(H,36,40) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [125I]Iodoproxyfan from histamine H3 receptor |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50209701
(3-[1,1-di(acetyloxymethyl)propyl]-1-(2'-methoxy-4-...)Show SMILES CCC(COC(C)=O)(COC(C)=O)NC(=O)N(CCC1CCN(Cc2ccc(C)cc2)CC1)Cc1ccc(cc1)-c1ccccc1OC Show InChI InChI=1S/C39H51N3O6/c1-6-39(27-47-30(3)43,28-48-31(4)44)40-38(45)42(26-34-15-17-35(18-16-34)36-9-7-8-10-37(36)46-5)24-21-32-19-22-41(23-20-32)25-33-13-11-29(2)12-14-33/h7-18,32H,6,19-28H2,1-5H3,(H,40,45) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description
Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cells |
Bioorg Med Chem 18: 7365-79 (2010)
Article DOI: 10.1016/j.bmc.2010.09.014
BindingDB Entry DOI: 10.7270/Q2D50N72 |
More data for this
Ligand-Target Pair | |
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