Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | 8.0 | 25 |
University of Karachi | Assay Description A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st... | Chem Biol Drug Des 86: 1115-20 (2015) Article DOI: 10.1111/cbdd.12579 BindingDB Entry DOI: 10.7270/Q2445K79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 4 (Homo sapiens (Human)) | BDBM50596624 (CHEMBL5204261) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50596640 (CHEMBL5194775) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50596640 (CHEMBL5194775) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50596637 (CHEMBL5188202) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 99 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM223077 ((E)-N'-(4'-Hydroxy-3-methoxybenzylidene)is...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50596637 (CHEMBL5188202) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 155 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM223080 ((E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dih...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM223079 ((E)-N'-(Pyridin-3'-ylmethylene)isonicotino...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM223076 ((E)-N'-(3'-Nitrobenzylidene)isonicotinohyd...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 4 (Homo sapiens (Human)) | BDBM50506158 (CHEMBL4521594) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 211 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM223072 ((E)-N'-(4'-Bromobenzylidene)isonicotinohyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM223074 ((E)-N'-(4'-Methoxybenzylidene)isonicotinoh...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 310 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle)) | BDBM223077 ((E)-N'-(4'-Hydroxy-3-methoxybenzylidene)is...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | 9.8 | 37 |
Quaid-I-Azam University | Assay Description The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM223080 ((E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dih...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 360 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM223073 ((E)-N'-(4'-Fluorobenzylidene)isonicotinohy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 440 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM223075 ((E)-N'-(2'-hydroxybenzylidene)isonicotinoh...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM167896 (3-(3′-Nitrophenyl)pyrido[2,3-b]pyrazine (6n)) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 466 | n/a | n/a | n/a | n/a | 8.0 | 25 |
University of Karachi | Assay Description A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st... | Chem Biol Drug Des 86: 1115-20 (2015) Article DOI: 10.1111/cbdd.12579 BindingDB Entry DOI: 10.7270/Q2445K79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle)) | BDBM223074 ((E)-N'-(4'-Methoxybenzylidene)isonicotinoh...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 560 | n/a | n/a | n/a | n/a | 9.8 | 37 |
Quaid-I-Azam University | Assay Description The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM167885 (3-(3′-Methylphenyl)pyrido[2,3-b]pyrazine (6c...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 583 | n/a | n/a | n/a | n/a | 8.0 | 25 |
University of Karachi | Assay Description A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st... | Chem Biol Drug Des 86: 1115-20 (2015) Article DOI: 10.1111/cbdd.12579 BindingDB Entry DOI: 10.7270/Q2445K79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal-type alkaline phosphatase (Bos taurus (Cattle)) | BDBM223071 ((E)-N'-(4'-Chlorobenzylidene)isonicotinohy...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 670 | n/a | n/a | n/a | n/a | 9.8 | 37 |
Quaid-I-Azam University | Assay Description The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM223077 ((E)-N'-(4'-Hydroxy-3-methoxybenzylidene)is...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 680 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50596635 (CHEMBL5184546) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 699 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 2 (Homo sapiens (Human)) | BDBM50596629 (CHEMBL5200337) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 732 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50596635 (CHEMBL5184546) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 796 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 2 (Homo sapiens (Human)) | BDBM50596632 (CHEMBL5187239) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 890 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM167888 (3-(3′-Fluorophenyl)pyrido[2,3-b]pyrazine (6f...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 899 | n/a | n/a | n/a | n/a | 8.0 | 25 |
University of Karachi | Assay Description A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st... | Chem Biol Drug Des 86: 1115-20 (2015) Article DOI: 10.1111/cbdd.12579 BindingDB Entry DOI: 10.7270/Q2445K79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle)) | BDBM223080 ((E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dih...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | 9.8 | 37 |
Quaid-I-Azam University | Assay Description The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 2 (Homo sapiens (Human)) | BDBM50596625 (CHEMBL5174645) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM223071 ((E)-N'-(4'-Chlorobenzylidene)isonicotinohy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 4 (Homo sapiens (Human)) | BDBM50596633 (CHEMBL5174595) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50596638 (CHEMBL5184167) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM167890 (3-(3′-Chlorophenyl)pyrido[2,3-b]pyrazine (6h...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | 8.0 | 25 |
University of Karachi | Assay Description A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st... | Chem Biol Drug Des 86: 1115-20 (2015) Article DOI: 10.1111/cbdd.12579 BindingDB Entry DOI: 10.7270/Q2445K79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 4 (Homo sapiens (Human)) | BDBM50596637 (CHEMBL5188202) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 4 (Homo sapiens (Human)) | BDBM50596625 (CHEMBL5174645) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 4 (Homo sapiens (Human)) | BDBM50596626 (CHEMBL5175938) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM223075 ((E)-N'-(2'-hydroxybenzylidene)isonicotinoh...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50596638 (CHEMBL5184167) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 2 (Homo sapiens (Human)) | BDBM50596631 (CHEMBL1615626) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal-type alkaline phosphatase (Bos taurus (Cattle)) | BDBM223075 ((E)-N'-(2'-hydroxybenzylidene)isonicotinoh...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.44E+3 | n/a | n/a | n/a | n/a | 9.8 | 37 |
Quaid-I-Azam University | Assay Description The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal-type alkaline phosphatase (Bos taurus (Cattle)) | BDBM223079 ((E)-N'-(Pyridin-3'-ylmethylene)isonicotino...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.46E+3 | n/a | n/a | n/a | n/a | 9.8 | 37 |
Quaid-I-Azam University | Assay Description The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50596633 (CHEMBL5174595) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 4 (Homo sapiens (Human)) | BDBM50596630 (CHEMBL5172961) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114162 BindingDB Entry DOI: 10.7270/Q2S46X0K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM223071 ((E)-N'-(4'-Chlorobenzylidene)isonicotinohy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.67E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal-type alkaline phosphatase (Bos taurus (Cattle)) | BDBM223074 ((E)-N'-(4'-Methoxybenzylidene)isonicotinoh...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.74E+3 | n/a | n/a | n/a | n/a | 9.8 | 37 |
Quaid-I-Azam University | Assay Description The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle)) | BDBM223076 ((E)-N'-(3'-Nitrobenzylidene)isonicotinohyd...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.82E+3 | n/a | n/a | n/a | n/a | 9.8 | 37 |
Quaid-I-Azam University | Assay Description The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM167896 (3-(3′-Nitrophenyl)pyrido[2,3-b]pyrazine (6n)) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.89E+3 | n/a | n/a | n/a | n/a | 8.0 | 25 |
University of Karachi | Assay Description A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st... | Chem Biol Drug Des 86: 1115-20 (2015) Article DOI: 10.1111/cbdd.12579 BindingDB Entry DOI: 10.7270/Q2445K79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM223076 ((E)-N'-(3'-Nitrobenzylidene)isonicotinohyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal-type alkaline phosphatase (Bos taurus (Cattle)) | BDBM223077 ((E)-N'-(4'-Hydroxy-3-methoxybenzylidene)is...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.92E+3 | n/a | n/a | n/a | n/a | 9.8 | 37 |
Quaid-I-Azam University | Assay Description The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM167895 (3-(4′-Nitrophenyl)pyrido[2,3-b]pyrazine (6m)) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.97E+3 | n/a | n/a | n/a | n/a | 8.0 | 25 |
University of Karachi | Assay Description A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st... | Chem Biol Drug Des 86: 1115-20 (2015) Article DOI: 10.1111/cbdd.12579 BindingDB Entry DOI: 10.7270/Q2445K79 | |||||||||||
More data for this Ligand-Target Pair |
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