Found 130 hits with Last Name = 'stanford' and Initial = 'sm' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393461
(CHEMBL2159938)Show SMILES CC(C)c1ccc(CN(Cc2ccccc2)C(c2nnnn2C2CCCC2)c2cc3cc(C)ccc3[nH]c2=O)cc1 Show InChI InChI=1S/C34H38N6O/c1-23(2)27-16-14-26(15-17-27)22-39(21-25-9-5-4-6-10-25)32(33-36-37-38-40(33)29-11-7-8-12-29)30-20-28-19-24(3)13-18-31(28)35-34(30)41/h4-6,9-10,13-20,23,29,32H,7-8,11-12,21-22H2,1-3H3,(H,35,41) | PDB
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393496
(CHEMBL2159935)Show SMILES Cc1ccc2[nH]c(=O)c(cc2c1)C(N1CCCC2(CCCCC2)C1)c1nnnn1C1CCCO1 Show InChI InChI=1S/C26H34N6O2/c1-18-8-9-21-19(15-18)16-20(25(33)27-21)23(24-28-29-30-32(24)22-7-5-14-34-22)31-13-6-12-26(17-31)10-3-2-4-11-26/h8-9,15-16,22-23H,2-7,10-14,17H2,1H3,(H,27,33) | PDB
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 3.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393463
(CHEMBL2159940)Show SMILES Cc1ccc2[nH]c(=O)c(cc2c1)C(N(Cc1ccccc1)Cc1ccc(Cl)cc1)c1nnnn1C1CCCC1 Show InChI InChI=1S/C31H31ClN6O/c1-21-11-16-28-24(17-21)18-27(31(39)33-28)29(30-34-35-36-38(30)26-9-5-6-10-26)37(19-22-7-3-2-4-8-22)20-23-12-14-25(32)15-13-23/h2-4,7-8,11-18,26,29H,5-6,9-10,19-20H2,1H3,(H,33,39) | PDB
UniProtKB/SwissProt
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| Article PubMed
| 8.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393461
(CHEMBL2159938)Show SMILES CC(C)c1ccc(CN(Cc2ccccc2)C(c2nnnn2C2CCCC2)c2cc3cc(C)ccc3[nH]c2=O)cc1 Show InChI InChI=1S/C34H38N6O/c1-23(2)27-16-14-26(15-17-27)22-39(21-25-9-5-4-6-10-25)32(33-36-37-38-40(33)29-11-7-8-12-29)30-20-28-19-24(3)13-18-31(28)35-34(30)41/h4-6,9-10,13-20,23,29,32H,7-8,11-12,21-22H2,1-3H3,(H,35,41) | PDB
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393462
(CHEMBL2159939)Show SMILES Cc1ccc2[nH]c(=O)c(cc2c1)C(N1CCN(CC1)C(c1ccccc1)c1ccccc1)c1nnnn1C1CCCC1 Show InChI InChI=1S/C34H37N7O/c1-24-16-17-30-27(22-24)23-29(34(42)35-30)32(33-36-37-38-41(33)28-14-8-9-15-28)40-20-18-39(19-21-40)31(25-10-4-2-5-11-25)26-12-6-3-7-13-26/h2-7,10-13,16-17,22-23,28,31-32H,8-9,14-15,18-21H2,1H3,(H,35,42) | PDB
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| Article PubMed
| 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM46264
(3-[2-azaspiro[5.5]undecan-2-yl-(1-cyclopentyl-1,2,...)Show SMILES Cc1ccc2[nH]c(=O)c(cc2c1)C(N1CCCC2(CCCCC2)C1)c1nnnn1C1CCCC1 Show InChI InChI=1S/C27H36N6O/c1-19-10-11-23-20(16-19)17-22(26(34)28-23)24(25-29-30-31-33(25)21-8-3-4-9-21)32-15-7-14-27(18-32)12-5-2-6-13-27/h10-11,16-17,21,24H,2-9,12-15,18H2,1H3,(H,28,34) | PDB
UniProtKB/SwissProt
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| Article PubMed
| 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393496
(CHEMBL2159935)Show SMILES Cc1ccc2[nH]c(=O)c(cc2c1)C(N1CCCC2(CCCCC2)C1)c1nnnn1C1CCCO1 Show InChI InChI=1S/C26H34N6O2/c1-18-8-9-21-19(15-18)16-20(25(33)27-21)23(24-28-29-30-32(24)22-7-5-14-34-22)31-13-6-12-26(17-31)10-3-2-4-11-26/h8-9,15-16,22-23H,2-7,10-14,17H2,1H3,(H,27,33) | PDB
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.76E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393462
(CHEMBL2159939)Show SMILES Cc1ccc2[nH]c(=O)c(cc2c1)C(N1CCN(CC1)C(c1ccccc1)c1ccccc1)c1nnnn1C1CCCC1 Show InChI InChI=1S/C34H37N7O/c1-24-16-17-30-27(22-24)23-29(34(42)35-30)32(33-36-37-38-41(33)28-14-8-9-15-28)40-20-18-39(19-21-40)31(25-10-4-2-5-11-25)26-12-6-3-7-13-26/h2-7,10-13,16-17,22-23,28,31-32H,8-9,14-15,18-21H2,1H3,(H,35,42) | PDB
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| 2.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393463
(CHEMBL2159940)Show SMILES Cc1ccc2[nH]c(=O)c(cc2c1)C(N(Cc1ccccc1)Cc1ccc(Cl)cc1)c1nnnn1C1CCCC1 Show InChI InChI=1S/C31H31ClN6O/c1-21-11-16-28-24(17-21)18-27(31(39)33-28)29(30-34-35-36-38(30)26-9-5-6-10-26)37(19-22-7-3-2-4-8-22)20-23-12-14-25(32)15-13-23/h2-4,7-8,11-18,26,29H,5-6,9-10,19-20H2,1H3,(H,33,39) | PDB
UniProtKB/SwissProt
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| 2.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50335895
(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)Show SMILES OC(=O)c1cc2c(-c3cn(CCCC(=O)Nc4cccc5ccccc45)nn3)c(oc2cc1O)-c1ccccc1 Show InChI InChI=1S/C31H24N4O5/c36-26-17-27-23(16-22(26)31(38)39)29(30(40-27)20-9-2-1-3-10-20)25-18-35(34-33-25)15-7-14-28(37)32-24-13-6-11-19-8-4-5-12-21(19)24/h1-6,8-13,16-18,36H,7,14-15H2,(H,32,37)(H,38,39) | PDB
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM46264
(3-[2-azaspiro[5.5]undecan-2-yl-(1-cyclopentyl-1,2,...)Show SMILES Cc1ccc2[nH]c(=O)c(cc2c1)C(N1CCCC2(CCCCC2)C1)c1nnnn1C1CCCC1 Show InChI InChI=1S/C27H36N6O/c1-19-10-11-23-20(16-19)17-22(26(34)28-23)24(25-29-30-31-33(25)21-8-3-4-9-21)32-15-7-14-27(18-32)12-5-2-6-13-27/h10-11,16-17,21,24H,2-9,12-15,18H2,1H3,(H,28,34) | PDB
UniProtKB/SwissProt
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Patents
Similars
| Article PubMed
| 3.81E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576941
(CHEMBL4875137)Show SMILES Cc1ccccc1-c1nc2c(N)ncn(Cc3c(Cl)cncc3Cl)c2n1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576927
(CHEMBL4856707)Show SMILES Cc1ccccc1-c1nc2c(N)ncn(Cc3c(Cl)cccc3Cl)c2n1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576940
(CHEMBL4857535) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576928
(CHEMBL4855952)Show SMILES Cc1cccc(c1)-c1nc2c(N)ncn(Cc3c(Cl)cccc3Cl)c2n1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576921
(CHEMBL4874911) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 104 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576933
(CHEMBL4848127)Show SMILES COc1ccccc1-c1nc2c(N)ncn(Cc3c(Cl)cccc3Cl)c2n1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 106 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576932
(CHEMBL4873827)Show SMILES Nc1ncn(Cc2c(Cl)cccc2Cl)c2nc(nc12)-c1ccc(F)cc1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 117 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576929
(CHEMBL4859307)Show SMILES Cc1ccc(cc1)-c1nc2c(N)ncn(Cc3c(Cl)cccc3Cl)c2n1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 119 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576930
(CHEMBL4858034)Show SMILES Nc1ncn(Cc2c(Cl)cccc2Cl)c2nc(nc12)-c1ccccc1F | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 147 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576924
(CHEMBL4861843)Show SMILES Nc1ncn(Cc2c(Cl)cccc2Cl)c2nc(nc12)-c1ccccc1Cl | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 171 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576931
(CHEMBL4870698)Show SMILES Nc1ncn(Cc2c(Cl)cccc2Cl)c2nc(nc12)-c1cccc(F)c1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 239 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576919
(CHEMBL4847980) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 239 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576934
(CHEMBL4868378)Show SMILES Nc1ncn(Cc2c(Cl)cccc2Cl)c2nc(nc12)-c1ccccc1C#N | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 245 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576926
(CHEMBL4857590)Show SMILES Nc1ncn(Cc2c(Cl)cccc2Cl)c2nc(nc12)-c1ccc(Cl)cc1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 288 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576920
(CHEMBL4852414) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 306 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576925
(CHEMBL4846731)Show SMILES Nc1ncn(Cc2c(Cl)cccc2Cl)c2nc(nc12)-c1cccc(Cl)c1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576936
(CHEMBL3228665) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576935
(CHEMBL3228662) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50576939
(CHEMBL4851570) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02126 BindingDB Entry DOI: 10.7270/Q21G0R2R |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393461
(CHEMBL2159938)Show SMILES CC(C)c1ccc(CN(Cc2ccccc2)C(c2nnnn2C2CCCC2)c2cc3cc(C)ccc3[nH]c2=O)cc1 Show InChI InChI=1S/C34H38N6O/c1-23(2)27-16-14-26(15-17-27)22-39(21-25-9-5-4-6-10-25)32(33-36-37-38-40(33)29-11-7-8-12-29)30-20-28-19-24(3)13-18-31(28)35-34(30)41/h4-6,9-10,13-20,23,29,32H,7-8,11-12,21-22H2,1-3H3,(H,35,41) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using pNPP substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM54792
(2-(3-cyano-5,8-dimethyl-quinolin-2-yl)sulfanyl-N-(...)Show SMILES CCc1cccc(C)c1NC(=O)CSc1nc2c(C)ccc(C)c2cc1C#N Show InChI InChI=1S/C23H23N3OS/c1-5-17-8-6-7-15(3)21(17)25-20(27)13-28-23-18(12-24)11-19-14(2)9-10-16(4)22(19)26-23/h6-11H,5,13H2,1-4H3,(H,25,27) | PDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using ARLIED-NEpYTAREG substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393496
(CHEMBL2159935)Show SMILES Cc1ccc2[nH]c(=O)c(cc2c1)C(N1CCCC2(CCCCC2)C1)c1nnnn1C1CCCO1 Show InChI InChI=1S/C26H34N6O2/c1-18-8-9-21-19(15-18)16-20(25(33)27-21)23(24-28-29-30-32(24)22-7-5-14-34-22)31-13-6-12-26(17-31)10-3-2-4-11-26/h8-9,15-16,22-23H,2-7,10-14,17H2,1H3,(H,27,33) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using pNPP substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393495
(CHEMBL2159725)Show SMILES CCOc1ccc2nc(NC(=O)CSc3nc4sc(C)c(C)c4c(=O)[nH]3)sc2c1 Show InChI InChI=1S/C19H18N4O3S3/c1-4-26-11-5-6-12-13(7-11)29-19(20-12)21-14(24)8-27-18-22-16(25)15-9(2)10(3)28-17(15)23-18/h5-7H,4,8H2,1-3H3,(H,20,21,24)(H,22,23,25) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using ARLIED-NEpYTAREG substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393462
(CHEMBL2159939)Show SMILES Cc1ccc2[nH]c(=O)c(cc2c1)C(N1CCN(CC1)C(c1ccccc1)c1ccccc1)c1nnnn1C1CCCC1 Show InChI InChI=1S/C34H37N7O/c1-24-16-17-30-27(22-24)23-29(34(42)35-30)32(33-36-37-38-41(33)28-14-8-9-15-28)40-20-18-39(19-21-40)31(25-10-4-2-5-11-25)26-12-6-3-7-13-26/h2-7,10-13,16-17,22-23,28,31-32H,8-9,14-15,18-21H2,1H3,(H,35,42) | PDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using pNPP substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393486
(CHEMBL2159960)Show SMILES CC(C)c1ccc(CN(Cc2ccccc2)C(c2nnnn2C2CCCC2)c2cc3ccc(C)cc3[nH]c2=O)cc1 Show InChI InChI=1S/C34H38N6O/c1-23(2)27-17-14-26(15-18-27)22-39(21-25-9-5-4-6-10-25)32(33-36-37-38-40(33)29-11-7-8-12-29)30-20-28-16-13-24(3)19-31(28)35-34(30)41/h4-6,9-10,13-20,23,29,32H,7-8,11-12,21-22H2,1-3H3,(H,35,41) | PDB
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using pNPP substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393487
(CHEMBL2159961)Show SMILES Cc1ccc2cc(C(N3CCN(CC3)C(c3ccccc3)c3ccccc3)c3nnnn3C3CCCC3)c(=O)[nH]c2c1 Show InChI InChI=1S/C34H37N7O/c1-24-16-17-27-23-29(34(42)35-30(27)22-24)32(33-36-37-38-41(33)28-14-8-9-15-28)40-20-18-39(19-21-40)31(25-10-4-2-5-11-25)26-12-6-3-7-13-26/h2-7,10-13,16-17,22-23,28,31-32H,8-9,14-15,18-21H2,1H3,(H,35,42) | PDB
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using pNPP substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 7
(Homo sapiens (Human)) | BDBM50393492
(CHEMBL2159933)Show InChI InChI=1S/C17H11ClN2OS2/c1-9-6-7-13-11(8-9)19-17(23-13)20-16(21)15-14(18)10-4-2-3-5-12(10)22-15/h2-8H,1H3,(H,19,20,21) | PDB
KEGG
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of HePTP expressed in Escherichia coli BL21 using pNPP substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 7
(Homo sapiens (Human)) | BDBM50393500
(CHEMBL2159726)Show InChI InChI=1S/C20H23N3OS/c1-13-8-9-15-10-16(11-21)20(23-19(15)14(13)2)25-12-18(24)22-17-6-4-3-5-7-17/h8-10,17H,3-7,12H2,1-2H3,(H,22,24) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of HePTP expressed in Escherichia coli BL21 using pNPP substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 7
(Homo sapiens (Human)) | BDBM50393495
(CHEMBL2159725)Show SMILES CCOc1ccc2nc(NC(=O)CSc3nc4sc(C)c(C)c4c(=O)[nH]3)sc2c1 Show InChI InChI=1S/C19H18N4O3S3/c1-4-26-11-5-6-12-13(7-11)29-19(20-12)21-14(24)8-27-18-22-16(25)15-9(2)10(3)28-17(15)23-18/h5-7H,4,8H2,1-3H3,(H,20,21,24)(H,22,23,25) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of HePTP expressed in Escherichia coli BL21 using pNPP substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393488
(CHEMBL2159962)Show SMILES Cc1ccc2cc(C(N3CCN(CC3)C(c3ccccc3)c3ccccc3)c3nnnn3C3CCCC3)c(=O)[nH]c2c1C Show InChI InChI=1S/C35H39N7O/c1-24-17-18-28-23-30(35(43)36-31(28)25(24)2)33(34-37-38-39-42(34)29-15-9-10-16-29)41-21-19-40(20-22-41)32(26-11-5-3-6-12-26)27-13-7-4-8-14-27/h3-8,11-14,17-18,23,29,32-33H,9-10,15-16,19-22H2,1-2H3,(H,36,43) | PDB
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using pNPP substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393463
(CHEMBL2159940)Show SMILES Cc1ccc2[nH]c(=O)c(cc2c1)C(N(Cc1ccccc1)Cc1ccc(Cl)cc1)c1nnnn1C1CCCC1 Show InChI InChI=1S/C31H31ClN6O/c1-21-11-16-28-24(17-21)18-27(31(39)33-28)29(30-34-35-36-38(30)26-9-5-6-10-26)37(19-22-7-3-2-4-8-22)20-23-12-14-25(32)15-13-23/h2-4,7-8,11-18,26,29H,5-6,9-10,19-20H2,1H3,(H,33,39) | PDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | 9.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using pNPP substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393489
(CHEMBL2159963)Show SMILES Cc1cc(C)c2[nH]c(=O)c(cc2c1)C(N1CCN(CC1)C(c1ccccc1)c1ccccc1)c1nnnn1C1CCCC1 Show InChI InChI=1S/C35H39N7O/c1-24-21-25(2)31-28(22-24)23-30(35(43)36-31)33(34-37-38-39-42(34)29-15-9-10-16-29)41-19-17-40(18-20-41)32(26-11-5-3-6-12-26)27-13-7-4-8-14-27/h3-8,11-14,21-23,29,32-33H,9-10,15-20H2,1-2H3,(H,36,43) | PDB
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using pNPP substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM46265
(2-[(2-cyclopropyl-5,6,7,8-tetrahydrobenzothiopheno...)Show SMILES O=C(CSc1nc(nc2sc3CCCCc3c12)C1CC1)NCc1ccc2OCOc2c1 Show InChI InChI=1S/C23H23N3O3S2/c27-19(24-10-13-5-8-16-17(9-13)29-12-28-16)11-30-22-20-15-3-1-2-4-18(15)31-23(20)26-21(25-22)14-6-7-14/h5,8-9,14H,1-4,6-7,10-12H2,(H,24,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 9.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using ARLIED-NEpYTAREG substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 7
(Homo sapiens (Human)) | BDBM54792
(2-(3-cyano-5,8-dimethyl-quinolin-2-yl)sulfanyl-N-(...)Show SMILES CCc1cccc(C)c1NC(=O)CSc1nc2c(C)ccc(C)c2cc1C#N Show InChI InChI=1S/C23H23N3OS/c1-5-17-8-6-7-15(3)21(17)25-20(27)13-28-23-18(12-24)11-19-14(2)9-10-16(4)22(19)26-23/h6-11H,5,13H2,1-4H3,(H,25,27) | PDB
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of HePTP expressed in Escherichia coli BL21 using pNPP substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein phosphatase C
(Homo sapiens (Human)) | BDBM54792
(2-(3-cyano-5,8-dimethyl-quinolin-2-yl)sulfanyl-N-(...)Show SMILES CCc1cccc(C)c1NC(=O)CSc1nc2c(C)ccc(C)c2cc1C#N Show InChI InChI=1S/C23H23N3OS/c1-5-17-8-6-7-15(3)21(17)25-20(27)13-28-23-18(12-24)11-19-14(2)9-10-16(4)22(19)26-23/h6-11H,5,13H2,1-4H3,(H,25,27) | PDB MMDB
Reactome pathway KEGG
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of CD45 |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393480
(CHEMBL2159955)Show SMILES Cc1cc(C)c2cc(C(N3CCCC4(CCCCC4)C3)c3nnnn3C3CCCC3)c(=O)[nH]c2c1 Show InChI InChI=1S/C28H38N6O/c1-19-15-20(2)22-17-23(27(35)29-24(22)16-19)25(26-30-31-32-34(26)21-9-4-5-10-21)33-14-8-13-28(18-33)11-6-3-7-12-28/h15-17,21,25H,3-14,18H2,1-2H3,(H,29,35) | PDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | 1.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using pNPP substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393497
(CHEMBL2159936)Show SMILES Cc1ccc2[nH]c(=O)c(cc2c1)C(N1CCCC2(CCCCC2)C1)c1nnnn1-c1ccccc1 Show InChI InChI=1S/C28H32N6O/c1-20-11-12-24-21(17-20)18-23(27(35)29-24)25(26-30-31-32-34(26)22-9-4-2-5-10-22)33-16-8-15-28(19-33)13-6-3-7-14-28/h2,4-5,9-12,17-18,25H,3,6-8,13-16,19H2,1H3,(H,29,35) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using pNPP substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM50393495
(CHEMBL2159725)Show SMILES CCOc1ccc2nc(NC(=O)CSc3nc4sc(C)c(C)c4c(=O)[nH]3)sc2c1 Show InChI InChI=1S/C19H18N4O3S3/c1-4-26-11-5-6-12-13(7-11)29-19(20-12)21-14(24)8-27-18-22-16(25)15-9(2)10(3)28-17(15)23-18/h5-7H,4,8H2,1-3H3,(H,20,21,24)(H,22,23,25) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using pNPP substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human)) | BDBM54792
(2-(3-cyano-5,8-dimethyl-quinolin-2-yl)sulfanyl-N-(...)Show SMILES CCc1cccc(C)c1NC(=O)CSc1nc2c(C)ccc(C)c2cc1C#N Show InChI InChI=1S/C23H23N3OS/c1-5-17-8-6-7-15(3)21(17)25-20(27)13-28-23-18(12-24)11-19-14(2)9-10-16(4)22(19)26-23/h6-11H,5,13H2,1-4H3,(H,25,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California
Curated by ChEMBL
| Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using pNPP substrate |
J Med Chem 54: 1640-54 (2011)
Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 |
More data for this Ligand-Target Pair | |