Compile Data Set for Download or QSAR

Found 1165 hits with Last Name = 'stevenson' and Initial = 'cs'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM531233 ((Z)-Methyl 3-(((4-(4-(2-((2-hydroxyethyl)amino)-2-...) Show SMILES COC(=O)c1cc2N(C(C)=O)C(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCN(CC(=O)OC(C)(C)C)CC3)c3ccccc3)c2cc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM445224 (US10669235, Example 15) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCN(CC(=O)NCCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H35N5O6/c1-21-18-26-27(19-25(21)33(43)44-2)36-31(41)29(26)30(22-6-4-3-5-7-22)35-24-10-8-23(9-11-24)32(42)38-15-13-37(14-16-38)20-28(40)34-12-17-39/h3-11,18-19,35,39H,12-17,20H2,1-2H3,(H,34,40)(H,36,41)/b30-29-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM445247 (US10669235, Example 38 | US11208381, Example 38) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCC(CO)(CN(C)C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C34H38N4O5/c1-22-18-27-28(19-26(22)33(42)43-4)36-31(40)29(27)30(23-8-6-5-7-9-23)35-25-12-10-24(11-13-25)32(41)38-16-14-34(21-39,15-17-38)20-37(2)3/h5-13,18-19,35,39H,14-17,20-21H2,1-4H3,(H,36,40)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM445247 (US10669235, Example 38 | US11208381, Example 38) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCC(CO)(CN(C)C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C34H38N4O5/c1-22-18-27-28(19-26(22)33(42)43-4)36-31(40)29(27)30(23-8-6-5-7-9-23)35-25-12-10-24(11-13-25)32(41)38-16-14-34(21-39,15-17-38)20-37(2)3/h5-13,18-19,35,39H,14-17,20-21H2,1-4H3,(H,36,40)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM445242 (US10669235, Example 33 | US11208381, Example 33) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CC[C@@H](CN(C)C)[C@H](O)C3)c3ccccc3)c2cc1C |r| Show InChI InChI=1S/C33H36N4O5/c1-20-16-26-27(17-25(20)33(41)42-4)35-31(39)29(26)30(21-8-6-5-7-9-21)34-24-12-10-22(11-13-24)32(40)37-15-14-23(18-36(2)3)28(38)19-37/h5-13,16-17,23,28,34,38H,14-15,18-19H2,1-4H3,(H,35,39)/b30-29-/t23-,28+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM445242 (US10669235, Example 33 | US11208381, Example 33) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CC[C@@H](CN(C)C)[C@H](O)C3)c3ccccc3)c2cc1C |r| Show InChI InChI=1S/C33H36N4O5/c1-20-16-26-27(17-25(20)33(41)42-4)35-31(39)29(26)30(21-8-6-5-7-9-21)34-24-12-10-22(11-13-24)32(40)37-15-14-23(18-36(2)3)28(38)19-37/h5-13,16-17,23,28,34,38H,14-15,18-19H2,1-4H3,(H,35,39)/b30-29-/t23-,28+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM445257 (US10669235, Example 48 | US11208381, Example 48) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N(C)[C@H]3CN(C)C[C@@H]3O)c3ccccc3)c2cc1C |r| Show InChI InChI=1S/C31H32N4O5/c1-18-14-23-24(15-22(18)31(39)40-4)33-29(37)27(23)28(19-8-6-5-7-9-19)32-21-12-10-20(11-13-21)30(38)35(3)25-16-34(2)17-26(25)36/h5-15,25-26,32,36H,16-17H2,1-4H3,(H,33,37)/b28-27-/t25-,26-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM445257 (US10669235, Example 48 | US11208381, Example 48) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N(C)[C@H]3CN(C)C[C@@H]3O)c3ccccc3)c2cc1C |r| Show InChI InChI=1S/C31H32N4O5/c1-18-14-23-24(15-22(18)31(39)40-4)33-29(37)27(23)28(19-8-6-5-7-9-19)32-21-12-10-20(11-13-21)30(38)35(3)25-16-34(2)17-26(25)36/h5-15,25-26,32,36H,16-17H2,1-4H3,(H,33,37)/b28-27-/t25-,26-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50026612 (BIBF-1120 | Nintedanib | US10981896, Compound Nint...) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)N(C)C(=O)CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1 Show InChI InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,32H,15-18,20H2,1-3H3,(H,33,38)/b29-28-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM445209 (US10669235, Nintedanib) Show SMILES COC(=O)c1ccc2c(C(=Nc3ccc(cc3)N(C)C(=O)CN3CCN(C)CC3)c3ccccc3)c(O)[nH]c2c1 |w:10.10| Show InChI InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,33,38H,15-18,20H2,1-3H3/b32-29+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50026612 (BIBF-1120 | Nintedanib | US10981896, Compound Nint...) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)N(C)C(=O)CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1 Show InChI InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,32H,15-18,20H2,1-3H3,(H,33,38)/b29-28-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM507109 (US11046672, Example 58) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N(C)OCCN3CCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM445255 (US10669235, Example 46 | US11208381, Example 46) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C32H34N4O5/c1-21-19-26-27(20-25(21)32(40)41-2)34-30(38)28(26)29(22-7-4-3-5-8-22)33-24-11-9-23(10-12-24)31(39)36-14-6-13-35(15-16-36)17-18-37/h3-5,7-12,19-20,33,37H,6,13-18H2,1-2H3,(H,34,38)/b29-28-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM445255 (US10669235, Example 46 | US11208381, Example 46) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C32H34N4O5/c1-21-19-26-27(20-25(21)32(40)41-2)34-30(38)28(26)29(22-7-4-3-5-8-22)33-24-11-9-23(10-12-24)31(39)36-14-6-13-35(15-16-36)17-18-37/h3-5,7-12,19-20,33,37H,6,13-18H2,1-2H3,(H,34,38)/b29-28-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM507056 ((Z)-Methyl 3-(((4-((2-(dimethylamino)ethoxy)carbam...) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(C(=O)NOCCN(C)C)c(C)c3)c3ccccc3)c2cc1C Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507078 (US11046672, Example 27) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NOCCCN(C)C)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445247 (US10669235, Example 38 | US11208381, Example 38) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCC(CO)(CN(C)C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C34H38N4O5/c1-22-18-27-28(19-26(22)33(42)43-4)36-31(40)29(27)30(23-8-6-5-7-9-23)35-25-12-10-24(11-13-25)32(41)38-16-14-34(21-39,15-17-38)20-37(2)3/h5-13,18-19,35,39H,14-17,20-21H2,1-4H3,(H,36,40)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445247 (US10669235, Example 38 | US11208381, Example 38) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCC(CO)(CN(C)C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C34H38N4O5/c1-22-18-27-28(19-26(22)33(42)43-4)36-31(40)29(27)30(23-8-6-5-7-9-23)35-25-12-10-24(11-13-25)32(41)38-16-14-34(21-39,15-17-38)20-37(2)3/h5-13,18-19,35,39H,14-17,20-21H2,1-4H3,(H,36,40)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445240 (US10669235, Example 31 | US11208381, Example 31) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCC(CC3)C(=O)NCCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C35H39N5O5/c1-22-20-28-29(21-27(22)35(44)45-4)38-33(42)30(28)31(23-8-6-5-7-9-23)37-26-12-10-25(11-13-26)34(43)40-17-14-24(15-18-40)32(41)36-16-19-39(2)3/h5-13,20-21,24,37H,14-19H2,1-4H3,(H,36,41)(H,38,42)/b31-30-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445240 (US10669235, Example 31 | US11208381, Example 31) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCC(CC3)C(=O)NCCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C35H39N5O5/c1-22-20-28-29(21-27(22)35(44)45-4)38-33(42)30(28)31(23-8-6-5-7-9-23)37-26-12-10-25(11-13-26)34(43)40-17-14-24(15-18-40)32(41)36-16-19-39(2)3/h5-13,20-21,24,37H,14-19H2,1-4H3,(H,36,41)(H,38,42)/b31-30-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507083 (US11046672, Example 32) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(C(=O)NOCCN4CCN(C)CC4)c(F)c3)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM445240 (US10669235, Example 31 | US11208381, Example 31) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCC(CC3)C(=O)NCCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C35H39N5O5/c1-22-20-28-29(21-27(22)35(44)45-4)38-33(42)30(28)31(23-8-6-5-7-9-23)37-26-12-10-25(11-13-26)34(43)40-17-14-24(15-18-40)32(41)36-16-19-39(2)3/h5-13,20-21,24,37H,14-19H2,1-4H3,(H,36,41)(H,38,42)/b31-30-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM445240 (US10669235, Example 31 | US11208381, Example 31) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCC(CC3)C(=O)NCCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C35H39N5O5/c1-22-20-28-29(21-27(22)35(44)45-4)38-33(42)30(28)31(23-8-6-5-7-9-23)37-26-12-10-25(11-13-26)34(43)40-17-14-24(15-18-40)32(41)36-16-19-39(2)3/h5-13,20-21,24,37H,14-19H2,1-4H3,(H,36,41)(H,38,42)/b31-30-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM445224 (US10669235, Example 15) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCN(CC(=O)NCCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H35N5O6/c1-21-18-26-27(19-25(21)33(43)44-2)36-31(41)29(26)30(22-6-4-3-5-7-22)35-24-10-8-23(9-11-24)32(42)38-15-13-37(14-16-38)20-28(40)34-12-17-39/h3-11,18-19,35,39H,12-17,20H2,1-2H3,(H,34,40)(H,36,41)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM531233 ((Z)-Methyl 3-(((4-(4-(2-((2-hydroxyethyl)amino)-2-...) Show SMILES COC(=O)c1cc2N(C(C)=O)C(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCN(CC(=O)OC(C)(C)C)CC3)c3ccccc3)c2cc1C Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM531233 ((Z)-Methyl 3-(((4-(4-(2-((2-hydroxyethyl)amino)-2-...) Show SMILES COC(=O)c1cc2N(C(C)=O)C(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCN(CC(=O)OC(C)(C)C)CC3)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445224 (US10669235, Example 15) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCN(CC(=O)NCCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H35N5O6/c1-21-18-26-27(19-25(21)33(43)44-2)36-31(41)29(26)30(22-6-4-3-5-7-22)35-24-10-8-23(9-11-24)32(42)38-15-13-37(14-16-38)20-28(40)34-12-17-39/h3-11,18-19,35,39H,12-17,20H2,1-2H3,(H,34,40)(H,36,41)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM445224 (US10669235, Example 15) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCN(CC(=O)NCCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H35N5O6/c1-21-18-26-27(19-25(21)33(43)44-2)36-31(41)29(26)30(22-6-4-3-5-7-22)35-24-10-8-23(9-11-24)32(42)38-15-13-37(14-16-38)20-28(40)34-12-17-39/h3-11,18-19,35,39H,12-17,20H2,1-2H3,(H,34,40)(H,36,41)/b30-29-	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM531233 ((Z)-Methyl 3-(((4-(4-(2-((2-hydroxyethyl)amino)-2-...) Show SMILES COC(=O)c1cc2N(C(C)=O)C(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCN(CC(=O)OC(C)(C)C)CC3)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445241 (US10669235, Example 32 | US11208381, Example 32) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N(CCO)CCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C31H34N4O5/c1-20-18-25-26(19-24(20)31(39)40-4)33-29(37)27(25)28(21-8-6-5-7-9-21)32-23-12-10-22(11-13-23)30(38)35(16-17-36)15-14-34(2)3/h5-13,18-19,32,36H,14-17H2,1-4H3,(H,33,37)/b28-27-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.02	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445241 (US10669235, Example 32 | US11208381, Example 32) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N(CCO)CCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C31H34N4O5/c1-20-18-25-26(19-24(20)31(39)40-4)33-29(37)27(25)28(21-8-6-5-7-9-21)32-23-12-10-22(11-13-23)30(38)35(16-17-36)15-14-34(2)3/h5-13,18-19,32,36H,14-17H2,1-4H3,(H,33,37)/b28-27-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.02	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM445220 (US10669235, Example 11 | US11208381, Example 11) Show SMILES CNC(=O)CN1CCN(CC1)C(=O)c1ccc(N\C(=C2/C(=O)Nc3cc(C(=O)OC)c(C)cc23)c2ccccc2)cc1 Show InChI InChI=1S/C32H33N5O5/c1-20-17-25-26(18-24(20)32(41)42-3)35-30(39)28(25)29(21-7-5-4-6-8-21)34-23-11-9-22(10-12-23)31(40)37-15-13-36(14-16-37)19-27(38)33-2/h4-12,17-18,34H,13-16,19H2,1-3H3,(H,33,38)(H,35,39)/b29-28-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.06	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM445220 (US10669235, Example 11 | US11208381, Example 11) Show SMILES CNC(=O)CN1CCN(CC1)C(=O)c1ccc(N\C(=C2/C(=O)Nc3cc(C(=O)OC)c(C)cc23)c2ccccc2)cc1 Show InChI InChI=1S/C32H33N5O5/c1-20-17-25-26(18-24(20)32(41)42-3)35-30(39)28(25)29(21-7-5-4-6-8-21)34-23-11-9-22(10-12-23)31(40)37-15-13-36(14-16-37)19-27(38)33-2/h4-12,17-18,34H,13-16,19H2,1-3H3,(H,33,38)(H,35,39)/b29-28-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.06	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM507111 (US11046672, Example 60) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N(C)OCCN3C4CCC3CNC4)c3ccccc3)c2cc1C |TLB:25:26:28.29:31.33.32| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM445226 (US10669235, Example 17 | US11208381, Example 17) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCN(C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C30H30N4O4/c1-19-17-24-25(18-23(19)30(37)38-3)32-28(35)26(24)27(20-7-5-4-6-8-20)31-22-11-9-21(10-12-22)29(36)34-15-13-33(2)14-16-34/h4-12,17-18,31H,13-16H2,1-3H3,(H,32,35)/b27-26-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM445226 (US10669235, Example 17 | US11208381, Example 17) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCN(C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C30H30N4O4/c1-19-17-24-25(18-23(19)30(37)38-3)32-28(35)26(24)27(20-7-5-4-6-8-20)31-22-11-9-21(10-12-22)29(36)34-15-13-33(2)14-16-34/h4-12,17-18,31H,13-16H2,1-3H3,(H,32,35)/b27-26-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM507108 (US11046672, Example 57) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N(C)OCCN3CCNCC3)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507090 (US11046672, Example 39) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)C(=O)NOCCN3CCN(CCO)CC3)c3ccccc3)C(=O)Nc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM507110 (US11046672, Example 59) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N(C)OCCN3C[C@@H]4C[C@H]3CN4)c3ccccc3)c2cc1C |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM445223 (US10669235, Example 14 | US10669235, Example 50 | ...) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC3CCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H36N4O5/c1-21-18-27-28(19-26(21)33(41)42-2)36-32(40)29(27)30(23-6-4-3-5-7-23)35-25-10-8-24(9-11-25)31(39)34-20-22-12-14-37(15-13-22)16-17-38/h3-11,18-19,22,35,38H,12-17,20H2,1-2H3,(H,34,39)(H,36,40)/b30-29-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM445223 (US10669235, Example 14 | US10669235, Example 50 | ...) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC3CCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H36N4O5/c1-21-18-27-28(19-26(21)33(41)42-2)36-32(40)29(27)30(23-6-4-3-5-7-23)35-25-10-8-24(9-11-25)31(39)34-20-22-12-14-37(15-13-22)16-17-38/h3-11,18-19,22,35,38H,12-17,20H2,1-2H3,(H,34,39)(H,36,40)/b30-29-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM445223 (US10669235, Example 14 | US10669235, Example 50 | ...) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC3CCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H36N4O5/c1-21-18-27-28(19-26(21)33(41)42-2)36-32(40)29(27)30(23-6-4-3-5-7-23)35-25-10-8-24(9-11-25)31(39)34-20-22-12-14-37(15-13-22)16-17-38/h3-11,18-19,22,35,38H,12-17,20H2,1-2H3,(H,34,39)(H,36,40)/b30-29-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM445223 (US10669235, Example 14 | US10669235, Example 50 | ...) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC3CCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H36N4O5/c1-21-18-27-28(19-26(21)33(41)42-2)36-32(40)29(27)30(23-6-4-3-5-7-23)35-25-10-8-24(9-11-25)31(39)34-20-22-12-14-37(15-13-22)16-17-38/h3-11,18-19,22,35,38H,12-17,20H2,1-2H3,(H,34,39)(H,36,40)/b30-29-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM507113 (US11046672, Example 62) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N(C)OCCN3CCN[C@@H](C)C3)c3ccccc3)c2cc1C |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445216 (US10669235, Example 7 | US11208381, Example 7) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC(=O)N3CCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H35N5O6/c1-21-18-26-27(19-25(21)33(43)44-2)36-32(42)29(26)30(22-6-4-3-5-7-22)35-24-10-8-23(9-11-24)31(41)34-20-28(40)38-14-12-37(13-15-38)16-17-39/h3-11,18-19,35,39H,12-17,20H2,1-2H3,(H,34,41)(H,36,42)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445216 (US10669235, Example 7 | US11208381, Example 7) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC(=O)N3CCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H35N5O6/c1-21-18-26-27(19-25(21)33(43)44-2)36-32(42)29(26)30(22-6-4-3-5-7-22)35-24-10-8-23(9-11-24)31(41)34-20-28(40)38-14-12-37(13-15-38)16-17-39/h3-11,18-19,35,39H,12-17,20H2,1-2H3,(H,34,41)(H,36,42)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50026612 (BIBF-1120 | Nintedanib | US10981896, Compound Nint...) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)N(C)C(=O)CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1 Show InChI InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,32H,15-18,20H2,1-3H3,(H,33,38)/b29-28-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM445209 (US10669235, Nintedanib) Show SMILES COC(=O)c1ccc2c(C(=Nc3ccc(cc3)N(C)C(=O)CN3CCN(C)CC3)c3ccccc3)c(O)[nH]c2c1 |w:10.10| Show InChI InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,33,38H,15-18,20H2,1-3H3/b32-29+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50026612 (BIBF-1120 | Nintedanib | US10981896, Compound Nint...) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)N(C)C(=O)CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1 Show InChI InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,32H,15-18,20H2,1-3H3,(H,33,38)/b29-28-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445230 (US10669235, Example 21 | US11208381, Example 21) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCCCN3CCN(C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H37N5O4/c1-22-20-27-28(21-26(22)33(41)42-3)36-32(40)29(27)30(23-8-5-4-6-9-23)35-25-12-10-24(11-13-25)31(39)34-14-7-15-38-18-16-37(2)17-19-38/h4-6,8-13,20-21,35H,7,14-19H2,1-3H3,(H,34,39)(H,36,40)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair

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