Compile Data Set for Download or QSAR

Found 536 hits with Last Name = 'surman' and Initial = 'md'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50184924 (1-((1S,2R,5S)-5-(4-cyanophenyl)bicyclo[3.1.0]hexan...) Show SMILES CN1CCN(CCCN([C@@H]2CC[C@@]3(C[C@H]23)c2ccc(cc2)C#N)C(=O)Nc2ccc(F)c(c2)C(F)(F)F)CC1 Show InChI InChI=1S/C29H33F4N5O/c1-36-13-15-37(16-14-36)11-2-12-38(27(39)35-22-7-8-25(30)23(17-22)29(31,32)33)26-9-10-28(18-24(26)28)21-5-3-20(19-34)4-6-21/h3-8,17,24,26H,2,9-16,18H2,1H3,(H,35,39)/t24-,26-,28-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7020-3 (2010) Article DOI: 10.1016/j.bmcl.2010.09.037 BindingDB Entry DOI: 10.7270/Q2639PZR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331198 (1-(5-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]ind...) Show SMILES CSc1ccc(cc1)-c1ccn(-c2ccc3c4CNCCc4n(C)c3c2)c(=O)c1 Show InChI InChI=1S/C24H23N3OS/c1-26-22-9-11-25-15-21(22)20-8-5-18(14-23(20)26)27-12-10-17(13-24(27)28)16-3-6-19(29-2)7-4-16/h3-8,10,12-14,25H,9,11,15H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7024-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.122 BindingDB Entry DOI: 10.7270/Q2XP7569
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331161 (4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...) Show SMILES O=c1cc(OCc2ccccc2)ccn1-c1ccc2n(CCN3CCCC3)ncc2c1 Show InChI InChI=1S/C25H26N4O2/c30-25-17-23(31-19-20-6-2-1-3-7-20)10-13-28(25)22-8-9-24-21(16-22)18-26-29(24)15-14-27-11-4-5-12-27/h1-3,6-10,13,16-18H,4-5,11-12,14-15,19H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7020-3 (2010) Article DOI: 10.1016/j.bmcl.2010.09.037 BindingDB Entry DOI: 10.7270/Q2639PZR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331161 (4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...) Show SMILES O=c1cc(OCc2ccccc2)ccn1-c1ccc2n(CCN3CCCC3)ncc2c1 Show InChI InChI=1S/C25H26N4O2/c30-25-17-23(31-19-20-6-2-1-3-7-20)10-13-28(25)22-8-9-24-21(16-22)18-26-29(24)15-14-27-11-4-5-12-27/h1-3,6-10,13,16-18H,4-5,11-12,14-15,19H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7015-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.039 BindingDB Entry DOI: 10.7270/Q2P55NSM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331199 (4-(4-methoxyphenyl)-1-(5-methyl-2,3,4,5-tetrahydro...) Show SMILES COc1ccc(cc1)-c1ccn(-c2ccc3c4CNCCc4n(C)c3c2)c(=O)c1 Show InChI InChI=1S/C24H23N3O2/c1-26-22-9-11-25-15-21(22)20-8-5-18(14-23(20)26)27-12-10-17(13-24(27)28)16-3-6-19(29-2)7-4-16/h3-8,10,12-14,25H,9,11,15H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7024-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.122 BindingDB Entry DOI: 10.7270/Q2XP7569
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331161 (4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...) Show SMILES O=c1cc(OCc2ccccc2)ccn1-c1ccc2n(CCN3CCCC3)ncc2c1 Show InChI InChI=1S/C25H26N4O2/c30-25-17-23(31-19-20-6-2-1-3-7-20)10-13-28(25)22-8-9-24-21(16-22)18-26-29(24)15-14-27-11-4-5-12-27/h1-3,6-10,13,16-18H,4-5,11-12,14-15,19H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7024-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.122 BindingDB Entry DOI: 10.7270/Q2XP7569
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331201 (4-(4-chlorophenyl)-1-(5-methyl-2,3,4,5-tetrahydro-...) Show SMILES Cn1c2CCNCc2c2ccc(cc12)-n1ccc(cc1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H20ClN3O/c1-26-21-8-10-25-14-20(21)19-7-6-18(13-22(19)26)27-11-9-16(12-23(27)28)15-2-4-17(24)5-3-15/h2-7,9,11-13,25H,8,10,14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7024-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.122 BindingDB Entry DOI: 10.7270/Q2XP7569
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331172 (4-(2-chloro-4-methoxyphenyl)-1-(1-(2-(pyrrolidin-1...) Show SMILES COc1ccc(c(Cl)c1)-c1ccn(-c2ccc3n(CCN4CCCC4)ncc3c2)c(=O)c1 Show InChI InChI=1S/C25H25ClN4O2/c1-32-21-5-6-22(23(26)16-21)18-8-11-29(25(31)15-18)20-4-7-24-19(14-20)17-27-30(24)13-12-28-9-2-3-10-28/h4-8,11,14-17H,2-3,9-10,12-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7020-3 (2010) Article DOI: 10.1016/j.bmcl.2010.09.037 BindingDB Entry DOI: 10.7270/Q2639PZR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50241083 (6-(4-chlorophenyl)-3-(3-methoxy-4-(2-(pyrrolidin-1...) Show SMILES COc1cc(ccc1OCCN1CCCC1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H24ClN3O3S/c1-31-22-14-19(8-9-21(22)32-13-12-28-10-2-3-11-28)29-16-27-20-15-23(33-24(20)25(29)30)17-4-6-18(26)7-5-17/h4-9,14-16H,2-3,10-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7020-3 (2010) Article DOI: 10.1016/j.bmcl.2010.09.037 BindingDB Entry DOI: 10.7270/Q2639PZR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331251 ((R)-4-(benzyloxy)-1-(1-(2-(2-(hydroxymethyl)pyrrol...) Show SMILES OC[C@H]1CCCN1CCn1ncc2cc(ccc12)-n1ccc(OCc2ccccc2)cc1=O |r| Show InChI InChI=1S/C26H28N4O3/c31-18-23-7-4-11-28(23)13-14-30-25-9-8-22(15-21(25)17-27-30)29-12-10-24(16-26(29)32)33-19-20-5-2-1-3-6-20/h1-3,5-6,8-10,12,15-17,23,31H,4,7,11,13-14,18-19H2/t23-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7015-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.039 BindingDB Entry DOI: 10.7270/Q2P55NSM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331170 (4-(2,4-dichlorophenyl)-1-(1-(2-(pyrrolidin-1-yl)et...) Show SMILES Clc1ccc(c(Cl)c1)-c1ccn(-c2ccc3n(CCN4CCCC4)ncc3c2)c(=O)c1 Show InChI InChI=1S/C24H22Cl2N4O/c25-19-3-5-21(22(26)15-19)17-7-10-29(24(31)14-17)20-4-6-23-18(13-20)16-27-30(23)12-11-28-8-1-2-9-28/h3-7,10,13-16H,1-2,8-9,11-12H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7020-3 (2010) Article DOI: 10.1016/j.bmcl.2010.09.037 BindingDB Entry DOI: 10.7270/Q2639PZR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331212 (4-(benzyloxy)-1-(2-(2-hydroxyethyl)-5-methyl-2,3,4...) Show SMILES Cn1c2CCN(CCO)Cc2c2ccc(cc12)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C26H27N3O3/c1-27-24-10-11-28(13-14-30)17-23(24)22-8-7-20(15-25(22)27)29-12-9-21(16-26(29)31)32-18-19-5-3-2-4-6-19/h2-9,12,15-16,30H,10-11,13-14,17-18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7024-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.122 BindingDB Entry DOI: 10.7270/Q2XP7569
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331187 (4-(benzyloxy)-1-(2,3,4,5-tetrahydro-1H-pyrido[4,3-...) Show SMILES O=c1cc(OCc2ccccc2)ccn1-c1ccc2c3CNCCc3[nH]c2c1 Show InChI InChI=1S/C23H21N3O2/c27-23-13-18(28-15-16-4-2-1-3-5-16)9-11-26(23)17-6-7-19-20-14-24-10-8-21(20)25-22(19)12-17/h1-7,9,11-13,24-25H,8,10,14-15H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7024-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.122 BindingDB Entry DOI: 10.7270/Q2XP7569
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331174 (4-(2-methyl-4-(trifluoromethoxy)phenyl)-1-(1-(2-(p...) Show SMILES Cc1cc(OC(F)(F)F)ccc1-c1ccn(-c2ccc3n(CCN4CCCC4)ncc3c2)c(=O)c1 Show InChI InChI=1S/C26H25F3N4O2/c1-18-14-22(35-26(27,28)29)5-6-23(18)19-8-11-32(25(34)16-19)21-4-7-24-20(15-21)17-30-33(24)13-12-31-9-2-3-10-31/h4-8,11,14-17H,2-3,9-10,12-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7020-3 (2010) Article DOI: 10.1016/j.bmcl.2010.09.037 BindingDB Entry DOI: 10.7270/Q2639PZR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331200 (1-(5-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]ind...) Show SMILES Cn1c2CCNCc2c2ccc(cc12)-n1ccc(cc1=O)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H20F3N3O/c1-29-21-8-10-28-14-20(21)19-7-6-18(13-22(19)29)30-11-9-16(12-23(30)31)15-2-4-17(5-3-15)24(25,26)27/h2-7,9,11-13,28H,8,10,14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7024-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.122 BindingDB Entry DOI: 10.7270/Q2XP7569
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331242 (2-(4-chloro-2-fluorophenyl)-5-(1-(2-(pyrrolidin-1-...) Show SMILES Fc1cc(Cl)ccc1-c1cc2c(ccn(-c3ccc4n(CCN5CCCC5)ncc4c3)c2=O)o1 Show InChI InChI=1S/C26H22ClFN4O2/c27-18-3-5-20(22(28)14-18)25-15-21-24(34-25)7-10-31(26(21)33)19-4-6-23-17(13-19)16-29-32(23)12-11-30-8-1-2-9-30/h3-7,10,13-16H,1-2,8-9,11-12H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7015-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.039 BindingDB Entry DOI: 10.7270/Q2P55NSM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331209 (4-(4-chlorobenzyloxy)-1-(5-methyl-2,3,4,5-tetrahyd...) Show SMILES Cn1c2CCNCc2c2ccc(cc12)-n1ccc(OCc2ccc(Cl)cc2)cc1=O Show InChI InChI=1S/C24H22ClN3O2/c1-27-22-8-10-26-14-21(22)20-7-6-18(12-23(20)27)28-11-9-19(13-24(28)29)30-15-16-2-4-17(25)5-3-16/h2-7,9,11-13,26H,8,10,14-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7024-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.122 BindingDB Entry DOI: 10.7270/Q2XP7569
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331186 (4-(benzyloxy)-1-(2,5-dimethyl-2,3,4,5-tetrahydro-1...) Show SMILES CN1CCc2c(C1)c1ccc(cc1n2C)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C25H25N3O2/c1-26-12-11-23-22(16-26)21-9-8-19(14-24(21)27(23)2)28-13-10-20(15-25(28)29)30-17-18-6-4-3-5-7-18/h3-10,13-15H,11-12,16-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7024-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.122 BindingDB Entry DOI: 10.7270/Q2XP7569
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM113660 (US8637501, 64) Show SMILES Cn1c2CCCNCc2c2ccc(cc12)N1CCN(CCc2ccc(Cl)cc2)CC1=O Show InChI InChI=1S/C25H29ClN4O/c1-28-23-3-2-11-27-16-22(23)21-9-8-20(15-24(21)28)30-14-13-29(17-25(30)31)12-10-18-4-6-19(26)7-5-18/h4-9,15,27H,2-3,10-14,16-17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.60	-47.6	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8637501 (2014) BindingDB Entry DOI: 10.7270/Q2B27SZ4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM113617 (US8637501, 21) Show SMILES Cn1c2CCCNCc2c2ccc(cc12)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C25H25N3O2/c1-27-23-8-5-12-26-16-22(23)21-10-9-19(14-24(21)27)28-13-11-20(15-25(28)29)30-17-18-6-3-2-4-7-18/h2-4,6-7,9-11,13-15,26H,5,8,12,16-17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.70	-47.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8637501 (2014) BindingDB Entry DOI: 10.7270/Q2B27SZ4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331234 ((S)-4-(benzyloxy)-1-(1-(2-(3-hydroxypyrrolidin-1-y...) Show SMILES O[C@H]1CCN(CCn2ncc3cc(ccc23)-n2ccc(OCc3ccccc3)cc2=O)C1 |r| Show InChI InChI=1S/C25H26N4O3/c30-22-8-10-27(17-22)12-13-29-24-7-6-21(14-20(24)16-26-29)28-11-9-23(15-25(28)31)32-18-19-4-2-1-3-5-19/h1-7,9,11,14-16,22,30H,8,10,12-13,17-18H2/t22-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7015-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.039 BindingDB Entry DOI: 10.7270/Q2P55NSM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM153245 (US8993765, 10) Show SMILES Cl.Cn1c2CCNCc2c2ccc(nc12)-n1ccc(cc1=O)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H19F3N4O.ClH/c1-29-19-8-10-27-13-18(19)17-6-7-20(28-22(17)29)30-11-9-15(12-21(30)31)14-2-4-16(5-3-14)23(24,25)26;/h2-7,9,11-12,27H,8,10,13H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.70	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8993765 (2015) BindingDB Entry DOI: 10.7270/Q2QZ28Q8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331245 (4-(benzyloxy)-1-(1-(2-(dimethylamino)ethyl)-1H-ind...) Show SMILES CN(C)CCn1ncc2cc(ccc12)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C23H24N4O2/c1-25(2)12-13-27-22-9-8-20(14-19(22)16-24-27)26-11-10-21(15-23(26)28)29-17-18-6-4-3-5-7-18/h3-11,14-16H,12-13,17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7015-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.039 BindingDB Entry DOI: 10.7270/Q2P55NSM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM113619 (US8637501, 23) Show SMILES Cn1c2CCCNCc2c2ccc(cc12)-n1ccc(cc1=O)-c1ccc(cn1)C(F)(F)F Show InChI InChI=1S/C24H21F3N4O/c1-30-21-3-2-9-28-14-19(21)18-6-5-17(12-22(18)30)31-10-8-15(11-23(31)32)20-7-4-16(13-29-20)24(25,26)27/h4-8,10-13,28H,2-3,9,14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.70	-47.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8637501 (2014) BindingDB Entry DOI: 10.7270/Q2B27SZ4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM113628 (US8637501, 32) Show SMILES CSc1ccc(cc1)-c1ccn(-c2ccc3c4CNCCCc4n(C)c3c2)c(=O)c1 Show InChI InChI=1S/C25H25N3OS/c1-27-23-4-3-12-26-16-22(23)21-10-7-19(15-24(21)27)28-13-11-18(14-25(28)29)17-5-8-20(30-2)9-6-17/h5-11,13-15,26H,3-4,12,16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.90	-47.4	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8637501 (2014) BindingDB Entry DOI: 10.7270/Q2B27SZ4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331185 (4-(benzyloxy)-1-(9-methyl-2,3,4,9-tetrahydro-1H-py...) Show SMILES Cn1c2CNCCc2c2ccc(cc12)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C24H23N3O2/c1-26-22-13-18(7-8-20(22)21-9-11-25-15-23(21)26)27-12-10-19(14-24(27)28)29-16-17-5-3-2-4-6-17/h2-8,10,12-14,25H,9,11,15-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7024-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.122 BindingDB Entry DOI: 10.7270/Q2XP7569
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM113625 (US8637501, 29) Show SMILES CN1CCCc2c(C1)c1ccc(cc1n2C)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C26H27N3O2/c1-27-13-6-9-24-23(17-27)22-11-10-20(15-25(22)28(24)2)29-14-12-21(16-26(29)30)31-18-19-7-4-3-5-8-19/h3-5,7-8,10-12,14-16H,6,9,13,17-18H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5	-47.4	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8637501 (2014) BindingDB Entry DOI: 10.7270/Q2B27SZ4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM113626 (US8637501, 30) Show SMILES CCN1CCCc2c(C1)c1ccc(cc1n2C)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C27H29N3O2/c1-3-29-14-7-10-25-24(18-29)23-12-11-21(16-26(23)28(25)2)30-15-13-22(17-27(30)31)32-19-20-8-5-4-6-9-20/h4-6,8-9,11-13,15-17H,3,7,10,14,18-19H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5	-47.4	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8637501 (2014) BindingDB Entry DOI: 10.7270/Q2B27SZ4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM113659 (US8637501, 63) Show SMILES Cn1c2CCCNCc2c2ccc(cc12)-n1ccc(OCc2ccc(Cl)cn2)cc1=O Show InChI InChI=1S/C24H23ClN4O2/c1-28-22-3-2-9-26-14-21(22)20-7-6-18(11-23(20)28)29-10-8-19(12-24(29)30)31-15-17-5-4-16(25)13-27-17/h4-8,10-13,26H,2-3,9,14-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5	-47.4	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8637501 (2014) BindingDB Entry DOI: 10.7270/Q2B27SZ4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331168 (1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)-4...) Show SMILES FC(F)(F)c1ccc(cc1)-c1ccn(-c2ccc3n(CCN4CCCC4)ncc3c2)c(=O)c1 Show InChI InChI=1S/C25H23F3N4O/c26-25(27,28)21-5-3-18(4-6-21)19-9-12-31(24(33)16-19)22-7-8-23-20(15-22)17-29-32(23)14-13-30-10-1-2-11-30/h3-9,12,15-17H,1-2,10-11,13-14H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7020-3 (2010) Article DOI: 10.1016/j.bmcl.2010.09.037 BindingDB Entry DOI: 10.7270/Q2639PZR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331236 (2-(4-chlorophenyl)-5-(1-(2-(pyrrolidin-1-yl)ethyl)...) Show SMILES Clc1ccc(cc1)-c1cc2c(ccn(-c3ccc4n(CCN5CCCC5)ncc4c3)c2=O)o1 Show InChI InChI=1S/C26H23ClN4O2/c27-20-5-3-18(4-6-20)25-16-22-24(33-25)9-12-30(26(22)32)21-7-8-23-19(15-21)17-28-31(23)14-13-29-10-1-2-11-29/h3-9,12,15-17H,1-2,10-11,13-14H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7015-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.039 BindingDB Entry DOI: 10.7270/Q2P55NSM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331184 (4-(benzyloxy)-1-(2,9-dimethyl-2,3,4,9-tetrahydro-1...) Show SMILES CN1CCc2c(C1)n(C)c1cc(ccc21)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C25H25N3O2/c1-26-12-11-22-21-9-8-19(14-23(21)27(2)24(22)16-26)28-13-10-20(15-25(28)29)30-17-18-6-4-3-5-7-18/h3-10,13-15H,11-12,16-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7024-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.122 BindingDB Entry DOI: 10.7270/Q2XP7569
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM113623 (US8637501, 27) Show SMILES Cn1c2CCCNCc2c2ccc(cc12)-n1ccc(cc1=O)-c1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C24H21F3N4O/c1-30-20-3-2-9-28-14-19(20)18-6-5-17(12-21(18)30)31-10-8-15(11-23(31)32)16-4-7-22(29-13-16)24(25,26)27/h4-8,10-13,28H,2-3,9,14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.30	-47.2	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8637501 (2014) BindingDB Entry DOI: 10.7270/Q2B27SZ4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM112722 (US8629158, 36) Show SMILES Cn1c2CC3CCC(N3)c2c2ccc(cc12)-n1ccc(cc1=O)-c1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C25H21F3N4O/c1-31-20-12-17(4-5-18(20)24-19-6-3-16(30-19)11-21(24)31)32-9-8-14(10-23(32)33)15-2-7-22(29-13-15)25(26,27)28/h2,4-5,7-10,12-13,16,19,30H,3,6,11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.30	-47.2	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8629158 (2014) BindingDB Entry DOI: 10.7270/Q24J0CS7
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331196 (4-(4-chlorophenyl)-1-(2,9-dimethyl-2,3,4,9-tetrahy...) Show SMILES CN1CCc2c(C1)n(C)c1cc(ccc21)-n1ccc(cc1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H22ClN3O/c1-26-11-10-21-20-8-7-19(14-22(20)27(2)23(21)15-26)28-12-9-17(13-24(28)29)16-3-5-18(25)6-4-16/h3-9,12-14H,10-11,15H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7024-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.122 BindingDB Entry DOI: 10.7270/Q2XP7569
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331171 (4-(2-chloro-4-(trifluoromethyl)phenyl)-1-(1-(2-(py...) Show SMILES FC(F)(F)c1ccc(c(Cl)c1)-c1ccn(-c2ccc3n(CCN4CCCC4)ncc3c2)c(=O)c1 Show InChI InChI=1S/C25H22ClF3N4O/c26-22-15-19(25(27,28)29)3-5-21(22)17-7-10-32(24(34)14-17)20-4-6-23-18(13-20)16-30-33(23)12-11-31-8-1-2-9-31/h3-7,10,13-16H,1-2,8-9,11-12H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7020-3 (2010) Article DOI: 10.1016/j.bmcl.2010.09.037 BindingDB Entry DOI: 10.7270/Q2639PZR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM113631 (US8637501, 35) Show SMILES O=c1cc(OCc2ccccc2)ccn1-c1ccc2c3CNCCCc3[nH]c2c1 Show InChI InChI=1S/C24H23N3O2/c28-24-14-19(29-16-17-5-2-1-3-6-17)10-12-27(24)18-8-9-20-21-15-25-11-4-7-22(21)26-23(20)13-18/h1-3,5-6,8-10,12-14,25-26H,4,7,11,15-16H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.80	-47.0	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8637501 (2014) BindingDB Entry DOI: 10.7270/Q2B27SZ4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM113709 (US8637501, 113) Show SMILES Cn1c2CCCNCc2c2ccc(nc12)-n1ccc(OCc2ccc(Cl)cc2)cc1=O Show InChI InChI=1S/C24H23ClN4O2/c1-28-21-3-2-11-26-14-20(21)19-8-9-22(27-24(19)28)29-12-10-18(13-23(29)30)31-15-16-4-6-17(25)7-5-16/h4-10,12-13,26H,2-3,11,14-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.90	-47.0	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8637501 (2014) BindingDB Entry DOI: 10.7270/Q2B27SZ4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM167874 (US9073925, 3) Show SMILES Cn1c2C3CCN(CC3)Cc2c2ccc(cc12)-n1ccc(OCc2ccccc2)cc1=O |(6.44,-1.2,;5.67,.13,;6.58,1.38,;8.12,1.38,;9.13,2.54,;8.85,4.05,;7.5,4.78,;6.95,3.67,;8.12,2.68,;6.08,4.18,;5.67,2.62,;4.21,2.15,;2.87,2.92,;1.54,2.15,;1.54,.61,;2.87,-.16,;4.21,.61,;.21,-.16,;.21,-1.7,;-1.13,-2.47,;-2.46,-1.7,;-3.79,-2.47,;-5.13,-1.7,;-6.46,-2.47,;-7.8,-1.7,;-9.13,-2.47,;-9.13,-4.01,;-7.8,-4.78,;-6.46,-4.01,;-2.46,-.16,;-1.13,.61,;-1.13,2.15,)| Show InChI InChI=1S/C27H27N3O2/c1-28-25-15-21(7-8-23(25)24-17-29-12-9-20(10-13-29)27(24)28)30-14-11-22(16-26(30)31)32-18-19-5-3-2-4-6-19/h2-8,11,14-16,20H,9-10,12-13,17-18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.90	-47.0	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US9073925 (2015) BindingDB Entry DOI: 10.7270/Q27S7MJ0
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM113603 (US8637501, 7) Show SMILES O=c1cc(OCc2ccccc2)ccn1-c1ccc2c3CCNCCc3[nH]c2c1 Show InChI InChI=1S/C24H23N3O2/c28-24-15-19(29-16-17-4-2-1-3-5-17)10-13-27(24)18-6-7-20-21-8-11-25-12-9-22(21)26-23(20)14-18/h1-7,10,13-15,25-26H,8-9,11-12,16H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6	-46.9	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8637501 (2014) BindingDB Entry DOI: 10.7270/Q2B27SZ4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM109806 (US8618299, 24) Show SMILES O=c1cc(OCc2ccccc2)ccn1-c1ccc2c3C4CCCN4CCc3[nH]c2c1 Show InChI InChI=1S/C26H25N3O2/c30-25-16-20(31-17-18-5-2-1-3-6-18)10-14-29(25)19-8-9-21-23(15-19)27-22-11-13-28-12-4-7-24(28)26(21)22/h1-3,5-6,8-10,14-16,24,27H,4,7,11-13,17H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8618299 (2013) BindingDB Entry DOI: 10.7270/Q2JW8CJ9
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM113699 (US8637501, 103) Show SMILES Cn1c2CCCNCc2c2ccc(cc12)-n1ccc(OCc2ccc(F)cc2)cc1=O Show InChI InChI=1S/C25H24FN3O2/c1-28-23-3-2-11-27-15-22(23)21-9-8-19(13-24(21)28)29-12-10-20(14-25(29)30)31-16-17-4-6-18(26)7-5-17/h4-10,12-14,27H,2-3,11,15-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6	-46.9	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8637501 (2014) BindingDB Entry DOI: 10.7270/Q2B27SZ4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331239 (2-(4-fluorophenyl)-5-(1-(2-(pyrrolidin-1-yl)ethyl)...) Show SMILES Fc1ccc(cc1)-c1cc2c(ccn(-c3ccc4n(CCN5CCCC5)ncc4c3)c2=O)o1 Show InChI InChI=1S/C26H23FN4O2/c27-20-5-3-18(4-6-20)25-16-22-24(33-25)9-12-30(26(22)32)21-7-8-23-19(15-21)17-28-31(23)14-13-29-10-1-2-11-29/h3-9,12,15-17H,1-2,10-11,13-14H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7015-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.039 BindingDB Entry DOI: 10.7270/Q2P55NSM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM113622 (US8637501, 26) Show SMILES Cn1c2CCCNCc2c2ccc(cc12)-n1ccc(cc1=O)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C25H22F3N3O/c1-30-22-3-2-11-29-15-21(22)20-9-8-19(14-23(20)30)31-12-10-17(13-24(31)32)16-4-6-18(7-5-16)25(26,27)28/h4-10,12-14,29H,2-3,11,15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.10	-46.9	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8637501 (2014) BindingDB Entry DOI: 10.7270/Q2B27SZ4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM113620 (US8637501, 24) Show SMILES Cn1c2CCCNCc2c2ccc(cc12)-n1ccc(OCc2ccc(nc2)C(F)(F)F)cc1=O Show InChI InChI=1S/C25H23F3N4O2/c1-31-21-3-2-9-29-14-20(21)19-6-5-17(11-22(19)31)32-10-8-18(12-24(32)33)34-15-16-4-7-23(30-13-16)25(26,27)28/h4-8,10-13,29H,2-3,9,14-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.40	-46.8	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8637501 (2014) BindingDB Entry DOI: 10.7270/Q2B27SZ4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM113686 (US8637501, 90) Show SMILES Cn1c2CCCNCc2c2ccc(nc12)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C24H24N4O2/c1-27-21-8-5-12-25-15-20(21)19-9-10-22(26-24(19)27)28-13-11-18(14-23(28)29)30-16-17-6-3-2-4-7-17/h2-4,6-7,9-11,13-14,25H,5,8,12,15-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.40	-46.8	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8637501 (2014) BindingDB Entry DOI: 10.7270/Q2B27SZ4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM167873 (US9073925, 2) Show SMILES Cn1c2C3CCN(C3)Cc2c2ccc(cc12)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C26H25N3O2/c1-27-24-13-20(7-8-22(24)23-16-28-11-9-19(15-28)26(23)27)29-12-10-21(14-25(29)30)31-17-18-5-3-2-4-6-18/h2-8,10,12-14,19H,9,11,15-17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.40	-46.8	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US9073925 (2015) BindingDB Entry DOI: 10.7270/Q27S7MJ0
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM112692 (US8629158, 5) Show SMILES Cn1c2CC3CCC(N3)c2c2ccc(cc12)-n1ccc(cc1=O)-c1ccc(nc1)C(F)(F)F |THB:10:9:8:6.5,1:2:8:6.5| Show InChI InChI=1S/C25H21F3N4O/c1-31-20-12-17(4-5-18(20)24-19-6-3-16(30-19)11-21(24)31)32-9-8-14(10-23(32)33)15-2-7-22(29-13-15)25(26,27)28/h2,4-5,7-10,12-13,16,19,30H,3,6,11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.5	-46.7	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8629158 (2014) BindingDB Entry DOI: 10.7270/Q24J0CS7
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50331210 (1-(5-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]ind...) Show SMILES Cn1c2CCNCc2c2ccc(cc12)-n1ccc(OCc2ccc(cc2)C(F)(F)F)cc1=O Show InChI InChI=1S/C25H22F3N3O2/c1-30-22-8-10-29-14-21(22)20-7-6-18(12-23(20)30)31-11-9-19(13-24(31)32)33-15-16-2-4-17(5-3-16)25(26,27)28/h2-7,9,11-13,29H,8,10,14-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7024-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.122 BindingDB Entry DOI: 10.7270/Q2XP7569
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM113683 (US8637501, 87) Show SMILES CCN1CCc2c(CC1)c1ccc(nc1n2C)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C26H28N4O2/c1-3-29-14-12-21-22-9-10-24(27-26(22)28(2)23(21)13-15-29)30-16-11-20(17-25(30)31)32-18-19-7-5-4-6-8-19/h4-11,16-17H,3,12-15,18H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.90	-46.6	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8637501 (2014) BindingDB Entry DOI: 10.7270/Q2B27SZ4
					More data for this Ligand-Target Pair

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