Compile Data Set for Download or QSAR

Found 30 hits with Last Name = 'tagami' and Initial = 'u'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid-binding protein, adipocyte (Homo sapiens (Human))	BDBM50177675 (CHEMBL3814634) Show SMILES CC(C)Oc1cccc(c1)-c1c(-c2c(C)n[nH]c2C)c2cc(ccc2n1CCC(O)=O)C1CC1 |(9.68,3.39,;8.99,2.37,;9.53,1.26,;7.45,2.48,;6.59,1.2,;7.27,-.19,;6.41,-1.46,;4.87,-1.36,;4.2,.03,;5.05,1.3,;2.66,.02,;1.76,-1.24,;2.24,-2.7,;3.66,-3.26,;4.7,-2.6,;3.55,-4.79,;2.05,-5.16,;1.24,-3.85,;.01,-3.75,;.3,-.77,;-1.03,-1.55,;-2.38,-.77,;-2.38,.77,;-1.03,1.55,;.3,.77,;1.76,1.24,;2.24,2.7,;3.75,3.01,;4.23,4.48,;3.41,5.4,;5.43,4.73,;-3.71,-1.53,;-4.4,-2.82,;-5.17,-1.49,)| Show InChI InChI=1S/C28H31N3O3/c1-16(2)34-22-7-5-6-21(14-22)28-27(26-17(3)29-30-18(26)4)23-15-20(19-8-9-19)10-11-24(23)31(28)13-12-25(32)33/h5-7,10-11,14-16,19H,8-9,12-13H2,1-4H3,(H,29,30)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Binding affinity to His-tagged human recombinant FABP4 expressed in Escherichia coli BL21 (DE3) by fluorescence assay				ACS Med Chem Lett 7: 435-9 (2016) Article DOI: 10.1021/acsmedchemlett.6b00040 BindingDB Entry DOI: 10.7270/Q2RX9F0J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fatty acid-binding protein, adipocyte (Homo sapiens (Human))	BDBM50177674 (CHEMBL3813892) Show SMILES COc1cnccc1-c1c(-c2ccccc2)n(CCC(O)=O)c2ccc(cc12)C1CC1 |(6.01,-2.39,;4.83,-2.05,;3.72,-3.12,;4.09,-4.62,;2.98,-5.68,;1.5,-5.26,;1.13,-3.76,;2.24,-2.7,;1.76,-1.24,;2.66,.02,;4.2,.03,;5.05,1.3,;6.59,1.2,;7.27,-.19,;6.41,-1.46,;4.87,-1.36,;1.76,1.24,;2.24,2.7,;3.75,3.01,;4.23,4.48,;3.41,5.4,;5.43,4.73,;.3,.77,;-1.03,1.55,;-2.38,.77,;-2.38,-.77,;-1.03,-1.55,;.3,-.77,;-3.71,-1.53,;-4.4,-2.82,;-5.17,-1.49,)| Show InChI InChI=1S/C26H24N2O3/c1-31-23-16-27-13-11-20(23)25-21-15-19(17-7-8-17)9-10-22(21)28(14-12-24(29)30)26(25)18-5-3-2-4-6-18/h2-6,9-11,13,15-17H,7-8,12,14H2,1H3,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Binding affinity to His-tagged human recombinant FABP4 expressed in Escherichia coli BL21 (DE3) by fluorescence assay				ACS Med Chem Lett 7: 435-9 (2016) Article DOI: 10.1021/acsmedchemlett.6b00040 BindingDB Entry DOI: 10.7270/Q2RX9F0J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fatty acid-binding protein, adipocyte (Homo sapiens (Human))	BDBM50177673 (CHEMBL3814575) Show SMILES OC(=O)CCn1c(c(-c2ccccc2)c2cc(ccc12)C1CC1)-c1ccccc1 Show InChI InChI=1S/C26H23NO2/c28-24(29)15-16-27-23-14-13-21(18-11-12-18)17-22(23)25(19-7-3-1-4-8-19)26(27)20-9-5-2-6-10-20/h1-10,13-14,17-18H,11-12,15-16H2,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Binding affinity to His-tagged human recombinant FABP4 expressed in Escherichia coli BL21 (DE3) by fluorescence assay				ACS Med Chem Lett 7: 435-9 (2016) Article DOI: 10.1021/acsmedchemlett.6b00040 BindingDB Entry DOI: 10.7270/Q2RX9F0J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fatty acid-binding protein, adipocyte (Homo sapiens (Human))	BDBM50212873 (((2'-(5-ETHYL-3,4-DIPHENYL-1H-PYRAZOL-1-YL)-3-BIPH...) Show SMILES CCc1c(c(nn1-c1ccccc1-c1cccc(OCC(O)=O)c1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C31H26N2O3/c1-2-27-30(22-12-5-3-6-13-22)31(23-14-7-4-8-15-23)32-33(27)28-19-10-9-18-26(28)24-16-11-17-25(20-24)36-21-29(34)35/h3-20H,2,21H2,1H3,(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Binding affinity to His-tagged human recombinant FABP4 expressed in Escherichia coli BL21 (DE3) by fluorescence assay				ACS Med Chem Lett 7: 435-9 (2016) Article DOI: 10.1021/acsmedchemlett.6b00040 BindingDB Entry DOI: 10.7270/Q2RX9F0J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fatty acid-binding protein, adipocyte (Homo sapiens (Human))	BDBM50177672 (CHEMBL1586017) Show SMILES OC(=O)CCn1c(cc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C17H15NO2/c19-17(20)10-11-18-15-9-5-4-8-14(15)12-16(18)13-6-2-1-3-7-13/h1-9,12H,10-11H2,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	>1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Binding affinity to His-tagged human recombinant FABP4 expressed in Escherichia coli BL21 (DE3) by fluorescence assay				ACS Med Chem Lett 7: 435-9 (2016) Article DOI: 10.1021/acsmedchemlett.6b00040 BindingDB Entry DOI: 10.7270/Q2RX9F0J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535463 (CHEMBL4452237) Show SMILES CC(C)(C)OC(=O)NCc1ccc(o1)-c1cncc(C(O)=O)c1N Show InChI InChI=1S/C16H19N3O5/c1-16(2,3)24-15(22)19-6-9-4-5-12(23-9)10-7-18-8-11(13(10)17)14(20)21/h4-5,7-8H,6H2,1-3H3,(H2,17,18)(H,19,22)(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.45E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535464 (CHEMBL4469334) Show SMILES CC(C)CNC(=O)NCc1ccc(o1)-c1cncc(C(O)=O)c1N Show InChI InChI=1S/C16H20N4O4/c1-9(2)5-19-16(23)20-6-10-3-4-13(24-10)11-7-18-8-12(14(11)17)15(21)22/h3-4,7-9H,5-6H2,1-2H3,(H2,17,18)(H,21,22)(H2,19,20,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.16E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535465 (CHEMBL4586146) Show SMILES CC(C)C[C@H](N)C(=O)NCc1ccc(o1)-c1cncc(C(O)=O)c1N |r| Show InChI InChI=1S/C17H22N4O4/c1-9(2)5-13(18)16(22)21-6-10-3-4-14(25-10)11-7-20-8-12(15(11)19)17(23)24/h3-4,7-9,13H,5-6,18H2,1-2H3,(H2,19,20)(H,21,22)(H,23,24)/t13-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.11E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535466 (CHEMBL4457270) Show SMILES N[C@@H](C1CCCCC1)C(=O)NCCCC(=O)Nc1cncc(C(O)=O)c1N |r| Show InChI InChI=1S/C18H27N5O4/c19-15(11-5-2-1-3-6-11)17(25)22-8-4-7-14(24)23-13-10-21-9-12(16(13)20)18(26)27/h9-11,15H,1-8,19H2,(H2,20,21)(H,22,25)(H,23,24)(H,26,27)/t15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.62E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535482 (CHEMBL4522824) Show SMILES CC(C)[C@@H](CCC(=O)Nc1cncc(C(O)=O)c1N)NC(=O)[C@@H](N)C1CCCCC1 |r| Show InChI InChI=1S/C21H33N5O4/c1-12(2)15(26-20(28)18(22)13-6-4-3-5-7-13)8-9-17(27)25-16-11-24-10-14(19(16)23)21(29)30/h10-13,15,18H,3-9,22H2,1-2H3,(H2,23,24)(H,25,27)(H,26,28)(H,29,30)/t15-,18+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.05E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535468 (CHEMBL4525425) Show SMILES C[C@@H](CC(=O)Nc1cncc(C(O)=O)c1N)NC(=O)[C@@H](N)C1CCCCC1 |r| Show InChI InChI=1S/C18H27N5O4/c1-10(22-17(25)15(19)11-5-3-2-4-6-11)7-14(24)23-13-9-21-8-12(16(13)20)18(26)27/h8-11,15H,2-7,19H2,1H3,(H2,20,21)(H,22,25)(H,23,24)(H,26,27)/t10-,15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.02E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535469 (CHEMBL4554779) Show SMILES CC(C)C[C@@H](CC(=O)Nc1cncc(C(O)=O)c1N)NC(=O)[C@@H](N)C1CCCCC1 |r| Show InChI InChI=1S/C21H33N5O4/c1-12(2)8-14(25-20(28)18(22)13-6-4-3-5-7-13)9-17(27)26-16-11-24-10-15(19(16)23)21(29)30/h10-14,18H,3-9,22H2,1-2H3,(H2,23,24)(H,25,28)(H,26,27)(H,29,30)/t14-,18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.27E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535470 (CHEMBL4483698) Show SMILES CC[C@H](C)[C@@H](CCC(=O)Nc1cncc(C(O)=O)c1N)NC(=O)[C@@H](N)C1CCCCC1 |r| Show InChI InChI=1S/C22H35N5O4/c1-3-13(2)16(27-21(29)19(23)14-7-5-4-6-8-14)9-10-18(28)26-17-12-25-11-15(20(17)24)22(30)31/h11-14,16,19H,3-10,23H2,1-2H3,(H2,24,25)(H,26,28)(H,27,29)(H,30,31)/t13-,16+,19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8.90E+6	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535471 (CHEMBL4549509) Show SMILES Nc1c(cncc1-c1ccccc1)C(O)=O Show InChI InChI=1S/C12H10N2O2/c13-11-9(8-4-2-1-3-5-8)6-14-7-10(11)12(15)16/h1-7H,(H2,13,14)(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.15E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535472 (CHEMBL4464976) Show SMILES Nc1c(cncc1-c1cccs1)C(O)=O Show InChI InChI=1S/C10H8N2O2S/c11-9-6(8-2-1-3-15-8)4-12-5-7(9)10(13)14/h1-5H,(H2,11,12)(H,13,14)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.10E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535473 (CHEMBL4473744) Show SMILES CC(C)C(=O)NCc1ccc(o1)-c1cncc(C(O)=O)c1N Show InChI InChI=1S/C15H17N3O4/c1-8(2)14(19)18-5-9-3-4-12(22-9)10-6-17-7-11(13(10)16)15(20)21/h3-4,6-8H,5H2,1-2H3,(H2,16,17)(H,18,19)(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.21E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535474 (CHEMBL4471408) Show SMILES CC[C@H](C)[C@H](N)C(=O)NCc1ccc(o1)-c1cncc(C(O)=O)c1N |r| Show InChI InChI=1S/C17H22N4O4/c1-3-9(2)14(18)16(22)21-6-10-4-5-13(25-10)11-7-20-8-12(15(11)19)17(23)24/h4-5,7-9,14H,3,6,18H2,1-2H3,(H2,19,20)(H,21,22)(H,23,24)/t9-,14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535475 (CHEMBL4450078) Show SMILES N[C@@H](C1CCCCC1)C(=O)N[C@H](CCC(=O)Nc1cncc(C(O)=O)c1N)Cc1ccccc1 |r| Show InChI InChI=1S/C25H33N5O4/c26-22(17-9-5-2-6-10-17)24(32)29-18(13-16-7-3-1-4-8-16)11-12-21(31)30-20-15-28-14-19(23(20)27)25(33)34/h1,3-4,7-8,14-15,17-18,22H,2,5-6,9-13,26H2,(H2,27,28)(H,29,32)(H,30,31)(H,33,34)/t18-,22+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8.50E+6	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535476 (CHEMBL4585719) Show SMILES CC(C)CNC(=O)C(=O)NCc1ccc(o1)-c1cncc(C(O)=O)c1N Show InChI InChI=1S/C17H20N4O5/c1-9(2)5-20-15(22)16(23)21-6-10-3-4-13(26-10)11-7-19-8-12(14(11)18)17(24)25/h3-4,7-9H,5-6H2,1-2H3,(H2,18,19)(H,20,22)(H,21,23)(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.65E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535477 (CHEMBL4561660) Show SMILES CC(C)NC(=O)C(C)(C)COc1cccc2nc(C)c(C(O)=O)c(N)c12 Show InChI InChI=1S/C19H25N3O4/c1-10(2)21-18(25)19(4,5)9-26-13-8-6-7-12-15(13)16(20)14(17(23)24)11(3)22-12/h6-8,10H,9H2,1-5H3,(H2,20,22)(H,21,25)(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535478 (CHEMBL4459681) Show SMILES CC(C)[C@H](N)C(=O)NCc1ccc(o1)-c1cncc(C(O)=O)c1N |r| Show InChI InChI=1S/C16H20N4O4/c1-8(2)13(17)15(21)20-5-9-3-4-12(24-9)10-6-19-7-11(14(10)18)16(22)23/h3-4,6-8,13H,5,17H2,1-2H3,(H2,18,19)(H,20,21)(H,22,23)/t13-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.46E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535479 (CHEMBL4440803) Show SMILES N[C@@H](C1CCCCC1)C(=O)NCCCCCCC(=O)Nc1cncc(C(O)=O)c1N |r| Show InChI InChI=1S/C21H33N5O4/c22-18(14-8-4-3-5-9-14)20(28)25-11-7-2-1-6-10-17(27)26-16-13-24-12-15(19(16)23)21(29)30/h12-14,18H,1-11,22H2,(H2,23,24)(H,25,28)(H,26,27)(H,29,30)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.02E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535480 (CHEMBL4458064) Show SMILES Nc1c(cncc1-c1ccco1)C(O)=O Show InChI InChI=1S/C10H8N2O3/c11-9-6(8-2-1-3-15-8)4-12-5-7(9)10(13)14/h1-5H,(H2,11,12)(H,13,14)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.68E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535481 (CHEMBL4454097) Show SMILES CC(C)(CC(=O)Nc1cncc(C(O)=O)c1N)NC(=O)[C@@H](N)C1CCCCC1 |r| Show InChI InChI=1S/C19H29N5O4/c1-19(2,24-17(26)15(20)11-6-4-3-5-7-11)8-14(25)23-13-10-22-9-12(16(13)21)18(27)28/h9-11,15H,3-8,20H2,1-2H3,(H2,21,22)(H,23,25)(H,24,26)(H,27,28)/t15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.20E+6	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535462 (CHEMBL4561537) Show SMILES Cc1nc2ccccc2c(N)c1C(O)=O Show InChI InChI=1S/C11H10N2O2/c1-6-9(11(14)15)10(12)7-4-2-3-5-8(7)13-6/h2-5H,1H3,(H2,12,13)(H,14,15)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.59E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535461 (CHEMBL4531239) Show SMILES N[C@@H](C1CCCCC1)C(=O)NCc1ccc(o1)-c1cncc(C(O)=O)c1N |r| Show InChI InChI=1S/C19H24N4O4/c20-16(11-4-2-1-3-5-11)18(24)23-8-12-6-7-15(27-12)13-9-22-10-14(17(13)21)19(25)26/h6-7,9-11,16H,1-5,8,20H2,(H2,21,22)(H,23,24)(H,25,26)/t16-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.80E+6	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535460 (CHEMBL4517824) Show SMILES CC(C)CC(=O)NCc1ccc(o1)-c1cncc(C(O)=O)c1N Show InChI InChI=1S/C16H19N3O4/c1-9(2)5-14(20)19-6-10-3-4-13(23-10)11-7-18-8-12(15(11)17)16(21)22/h3-4,7-9H,5-6H2,1-2H3,(H2,17,18)(H,19,20)(H,21,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.83E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535459 (CHEMBL4531637) Show SMILES CC(C)[C@@H](CC(=O)Nc1cncc(C(O)=O)c1N)NC(=O)[C@@H](N)C1CCCCC1 |r| Show InChI InChI=1S/C20H31N5O4/c1-11(2)14(25-19(27)17(21)12-6-4-3-5-7-12)8-16(26)24-15-10-23-9-13(18(15)22)20(28)29/h9-12,14,17H,3-8,21H2,1-2H3,(H2,22,23)(H,24,26)(H,25,27)(H,28,29)/t14-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.84E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535458 (CHEMBL4525445) Show SMILES CC(=O)NCc1ccc(o1)-c1cncc(C(O)=O)c1N Show InChI InChI=1S/C13H13N3O4/c1-7(17)16-4-8-2-3-11(20-8)9-5-15-6-10(12(9)14)13(18)19/h2-3,5-6H,4H2,1H3,(H2,14,15)(H,16,17)(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.71E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair
Taste receptor type 1 member 2/3 (Homo sapiens (Human))	BDBM50535467 (CHEMBL4542114) Show SMILES N[C@@H](C1CCCCC1)C(=O)NCCCCC(=O)Nc1cncc(C(O)=O)c1N |r| Show InChI InChI=1S/C19H29N5O4/c20-16(12-6-2-1-3-7-12)18(26)23-9-5-4-8-15(25)24-14-11-22-10-13(17(14)21)19(27)28/h10-12,16H,1-9,20H2,(H2,21,22)(H,23,26)(H,24,25)(H,27,28)/t16-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.80E+6	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051 BindingDB Entry DOI: 10.7270/Q2348PXB
					More data for this Ligand-Target Pair