Compile Data Set for Download or QSAR

Found 59 hits with Last Name = 'tigyi' and Initial = 'gj'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233168 (CHEMBL4085965 | US11124490, Compound 11) Show SMILES Fc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1F Show InChI InChI=1S/C17H13Cl2F3N2O4S/c18-11-8-12(19)15(29(26,27)24-1-3-28-4-2-24)7-10(11)17(25)23-9-5-13(20)16(22)14(21)6-9/h5-8H,1-4H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233187 (CHEMBL4079588) Show SMILES Fc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)c(Br)c(F)c1F Show InChI InChI=1S/C17H12BrCl2F3N2O4S/c18-14-12(7-11(21)15(22)16(14)23)24-17(26)8-5-13(10(20)6-9(8)19)30(27,28)25-1-3-29-4-2-25/h5-7H,1-4H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233154 (CHEMBL4096134 | US11124490, Compound 10) Show SMILES Fc1ccc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc1F Show InChI InChI=1S/C17H14Cl2F2N2O4S/c18-12-9-13(19)16(28(25,26)23-3-5-27-6-4-23)8-11(12)17(24)22-10-1-2-14(20)15(21)7-10/h1-2,7-9H,3-6H2,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233173 (CHEMBL4094366 | US11124490, Compound 14) Show SMILES Fc1cc(NC(=S)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1F Show InChI InChI=1S/C17H13Cl2F3N2O3S2/c18-11-8-12(19)15(29(25,26)24-1-3-27-4-2-24)7-10(11)17(28)23-9-5-13(20)16(22)14(21)6-9/h5-8H,1-4H2,(H,23,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233166 (CHEMBL4060128 | US11124490, Compound 3g) Show SMILES Fc1c(Cl)cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc1Cl Show InChI InChI=1S/C17H13Cl4FN2O4S/c18-11-8-12(19)15(29(26,27)24-1-3-28-4-2-24)7-10(11)17(25)23-9-5-13(20)16(22)14(21)6-9/h5-8H,1-4H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233155 (CHEMBL4080953 | US11124490, Compound 28b) Show SMILES CN1CCN(CC1)S(=O)(=O)c1cc(C(=O)Nc2cc(Cl)c(F)c(Cl)c2)c(Cl)cc1Cl Show InChI InChI=1S/C18H16Cl4FN3O3S/c1-25-2-4-26(5-3-25)30(28,29)16-8-11(12(19)9-13(16)20)18(27)24-10-6-14(21)17(23)15(22)7-10/h6-9H,2-5H2,1H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of ATX (unknown origin) expressed in human A2058 cells assessed as inhibition of LPC-induced cell invasion after 20 hrs by calcein-AM dye ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233157 (CHEMBL4097500 | US11124490, Compound 28a) Show SMILES CN1CCN(CC1)S(=O)(=O)c1cc(C(=O)Nc2cc(F)c(F)c(F)c2)c(Cl)cc1Cl Show InChI InChI=1S/C18H16Cl2F3N3O3S/c1-25-2-4-26(5-3-25)30(28,29)16-8-11(12(19)9-13(16)20)18(27)24-10-6-14(21)17(23)15(22)7-10/h6-9H,2-5H2,1H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233170 (CHEMBL4073772 | US11124490, Compound 13) Show SMILES Fc1ccc(NC(=S)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc1F Show InChI InChI=1S/C17H14Cl2F2N2O3S2/c18-12-9-13(19)16(28(24,25)23-3-5-26-6-4-23)8-11(12)17(27)22-10-1-2-14(20)15(21)7-10/h1-2,7-9H,3-6H2,(H,22,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233169 (CHEMBL4082022 | US11124490, Compound 3f) Show SMILES Fc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1Cl Show InChI InChI=1S/C17H13Cl3F2N2O4S/c18-11-8-12(19)15(29(26,27)24-1-3-28-4-2-24)7-10(11)17(25)23-9-5-13(21)16(20)14(22)6-9/h5-8H,1-4H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233171 (CHEMBL4099620 | US11124490, Compound 15) Show SMILES Fc1c(Cl)cc(NC(=S)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc1Cl Show InChI InChI=1S/C17H13Cl4FN2O3S2/c18-11-8-12(19)15(29(25,26)24-1-3-27-4-2-24)7-10(11)17(28)23-9-5-13(20)16(22)14(21)6-9/h5-8H,1-4H2,(H,23,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233164 (CHEMBL4105201 | US11124490, Compound 29) Show SMILES CN1CCN(CC1)S(=O)(=O)c1cc(C(=S)Nc2cc(Cl)c(F)c(Cl)c2)c(Cl)cc1Cl Show InChI InChI=1S/C18H16Cl4FN3O2S2/c1-25-2-4-26(5-3-25)30(27,28)16-8-11(12(19)9-13(16)20)18(29)24-10-6-14(21)17(23)15(22)7-10/h6-9H,2-5H2,1H3,(H,24,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50187686 (CHEMBL3828074 | US10526329, Compound 2 | US1107261...) Show SMILES CCc1nc2c(C)cc(cn2c1N(C)c1nc(c(s1)C#N)-c1ccc(F)cc1)N1CCN(CC(=O)N2CC(O)C2)CC1 Show InChI InChI=1S/C30H33FN8O2S/c1-4-24-29(35(3)30-34-27(25(14-32)42-30)20-5-7-21(31)8-6-20)39-15-22(13-19(2)28(39)33-24)37-11-9-36(10-12-37)18-26(41)38-16-23(40)17-38/h5-8,13,15,23,40H,4,9-12,16-18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of ATX (unknown origin)				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50187687 (CHEMBL3828733 | US11124490, Compound 918013) Show SMILES Fc1cccc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)c1 Show InChI InChI=1S/C17H15Cl2FN2O4S/c18-14-10-15(19)16(27(24,25)22-4-6-26-7-5-22)9-13(14)17(23)21-12-3-1-2-11(20)8-12/h1-3,8-10H,4-7H2,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of ATX (unknown origin)				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50187687 (CHEMBL3828733 | US11124490, Compound 918013) Show SMILES Fc1cccc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)c1 Show InChI InChI=1S/C17H15Cl2FN2O4S/c18-14-10-15(19)16(27(24,25)22-4-6-26-7-5-22)9-13(14)17(23)21-12-3-1-2-11(20)8-12/h1-3,8-10H,4-7H2,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233163 (CHEMBL4102111 | US11124490, Compound 12) Show SMILES Fc1cccc(NC(=S)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)c1 Show InChI InChI=1S/C17H15Cl2FN2O3S2/c18-14-10-15(19)16(27(23,24)22-4-6-25-7-5-22)9-13(14)17(26)21-12-3-1-2-11(20)8-12/h1-3,8-10H,4-7H2,(H,21,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233160 (CHEMBL4071490 | US11124490, Compound 3h) Show SMILES Fc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1C#N Show InChI InChI=1S/C18H13Cl2F2N3O4S/c19-13-8-14(20)17(30(27,28)25-1-3-29-4-2-25)7-11(13)18(26)24-10-5-15(21)12(9-23)16(22)6-10/h5-8H,1-4H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233161 (CHEMBL4084129) Show SMILES Fc1cc(NCc2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1F Show InChI InChI=1S/C17H15Cl2F3N2O3S/c18-12-8-13(19)16(28(25,26)24-1-3-27-4-2-24)5-10(12)9-23-11-6-14(20)17(22)15(21)7-11/h5-8,23H,1-4,9H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	396	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233173 (CHEMBL4094366 | US11124490, Compound 14) Show SMILES Fc1cc(NC(=S)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1F Show InChI InChI=1S/C17H13Cl2F3N2O3S2/c18-11-8-12(19)15(29(25,26)24-1-3-27-4-2-24)7-10(11)17(28)23-9-5-13(20)16(22)14(21)6-9/h5-8H,1-4H2,(H,23,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	403	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of ATX (unknown origin) expressed in human A2058 cells assessed as inhibition of LPC-induced cell invasion after 20 hrs by calcein-AM dye ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233154 (CHEMBL4096134 | US11124490, Compound 10) Show SMILES Fc1ccc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc1F Show InChI InChI=1S/C17H14Cl2F2N2O4S/c18-12-9-13(19)16(28(25,26)23-3-5-27-6-4-23)8-11(12)17(24)22-10-1-2-14(20)15(21)7-10/h1-2,7-9H,3-6H2,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	528	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of ATX (unknown origin) expressed in human A2058 cells assessed as inhibition of LPC-induced cell invasion after 20 hrs by calcein-AM dye ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233169 (CHEMBL4082022 | US11124490, Compound 3f) Show SMILES Fc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1Cl Show InChI InChI=1S/C17H13Cl3F2N2O4S/c18-11-8-12(19)15(29(26,27)24-1-3-28-4-2-24)7-10(11)17(25)23-9-5-13(21)16(20)14(22)6-9/h5-8H,1-4H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of ATX (unknown origin) expressed in human A2058 cells assessed as inhibition of LPC-induced cell invasion after 20 hrs by calcein-AM dye ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233188 (CHEMBL4098521 | US11124490, Compound 3i) Show SMILES COC(=O)c1c(F)cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc1F Show InChI InChI=1S/C19H16Cl2F2N2O6S/c1-30-19(27)17-14(22)6-10(7-15(17)23)24-18(26)11-8-16(13(21)9-12(11)20)32(28,29)25-2-4-31-5-3-25/h6-9H,2-5H2,1H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	864	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233186 (CHEMBL4070002 | US11124490, Compound 23) Show SMILES Fc1cc(NS(=O)(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1F Show InChI InChI=1S/C16H13Cl2F3N2O5S2/c17-10-7-11(18)15(30(26,27)23-1-3-28-4-2-23)8-14(10)29(24,25)22-9-5-12(19)16(21)13(20)6-9/h5-8,22H,1-4H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233156 (CHEMBL4070321 | US11124490, Compound 26a) Show SMILES CS(=O)(=O)N(C(=O)c1cc(NN2CCOCC2)c(Cl)cc1Cl)c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C18H16Cl2F3N3O4S/c1-31(28,29)26(10-6-14(21)17(23)15(22)7-10)18(27)11-8-16(13(20)9-12(11)19)24-25-2-4-30-5-3-25/h6-9,24H,2-5H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233158 (CHEMBL4097621) Show SMILES COc1cc(Cl)c(cc1S(=O)(=O)N1CCOCC1)C(=O)Nc1cc(F)c(C(O)=O)c(F)c1 Show InChI InChI=1S/C19H17ClF2N2O7S/c1-30-15-9-12(20)11(8-16(15)32(28,29)24-2-4-31-5-3-24)18(25)23-10-6-13(21)17(19(26)27)14(22)7-10/h6-9H,2-5H2,1H3,(H,23,25)(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233167 (CHEMBL4091887 | US11124490, Compound 20) Show SMILES Fc1cccc(c1)S(=O)(=O)N(c1cc(c(Cl)cc1Cl)S(=O)(=O)N1CCOCC1)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C22H18Cl2F2N2O7S3/c23-19-13-20(24)22(38(33,34)27-7-9-35-10-8-27)14-21(19)28(36(29,30)17-5-1-3-15(25)11-17)37(31,32)18-6-2-4-16(26)12-18/h1-6,11-14H,7-10H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233172 (CHEMBL4093264) Show SMILES CN(C(=O)c1cc(c(Cl)cc1Cl)S(=O)(=O)N1CCOCC1)c1cccc(F)c1 Show InChI InChI=1S/C18H17Cl2FN2O4S/c1-22(13-4-2-3-12(21)9-13)18(24)14-10-17(16(20)11-15(14)19)28(25,26)23-5-7-27-8-6-23/h2-4,9-11H,5-8H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233159 (CHEMBL4072723 | US11124490, Compound 19) Show SMILES Fc1cccc(c1)S(=O)(=O)Nc1cc(c(Cl)cc1Cl)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C16H15Cl2FN2O5S2/c17-13-9-14(18)16(28(24,25)21-4-6-26-7-5-21)10-15(13)20-27(22,23)12-3-1-2-11(19)8-12/h1-3,8-10,20H,4-7H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233176 (CHEMBL4068789) Show SMILES Fc1cc2nc([nH]c2cc1F)-c1cc(c(Cl)cc1Cl)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C17H13Cl2F2N3O3S/c18-10-6-11(19)16(28(25,26)24-1-3-27-4-2-24)5-9(10)17-22-14-7-12(20)13(21)8-15(14)23-17/h5-8H,1-4H2,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233184 (CHEMBL4064138 | US11124490, Compound 22) Show SMILES Fc1cccc(NS(=O)(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)c1 Show InChI InChI=1S/C16H15Cl2FN2O5S2/c17-13-9-14(18)16(28(24,25)21-4-6-26-7-5-21)10-15(13)27(22,23)20-12-3-1-2-11(19)8-12/h1-3,8-10,20H,4-7H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233175 (CHEMBL4072530) Show SMILES Fc1ccc(NCc2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc1F Show InChI InChI=1S/C17H16Cl2F2N2O3S/c18-13-9-14(19)17(27(24,25)23-3-5-26-6-4-23)7-11(13)10-22-12-1-2-15(20)16(21)8-12/h1-2,7-9,22H,3-6,10H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233185 (CHEMBL4090985 | US11124490, Compound 25) Show SMILES Fc1cc(NC(=O)c2cc(NN3CCOCC3)c(Cl)cc2Cl)cc(F)c1F Show InChI InChI=1S/C17H14Cl2F3N3O2/c18-11-8-12(19)15(24-25-1-3-27-4-2-25)7-10(11)17(26)23-9-5-13(20)16(22)14(21)6-9/h5-8,24H,1-4H2,(H,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233183 (CHEMBL4091756 | US11124490, Compound 3e) Show SMILES COc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(OC)c1OC Show InChI InChI=1S/C20H22Cl2N2O7S/c1-28-16-8-12(9-17(29-2)19(16)30-3)23-20(25)13-10-18(15(22)11-14(13)21)32(26,27)24-4-6-31-7-5-24/h8-11H,4-7H2,1-3H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233177 (CHEMBL4070890 | US11124490, Compound 3d) Show SMILES Clc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(Cl)c1Cl Show InChI InChI=1S/C17H13Cl5N2O4S/c18-11-8-12(19)15(29(26,27)24-1-3-28-4-2-24)7-10(11)17(25)23-9-5-13(20)16(22)14(21)6-9/h5-8H,1-4H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233162 (CHEMBL4089884) Show SMILES Fc1cccc2nc(oc12)-c1cc(c(Cl)cc1Cl)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C17H13Cl2FN2O4S/c18-11-9-12(19)15(27(23,24)22-4-6-25-7-5-22)8-10(11)17-21-14-3-1-2-13(20)16(14)26-17/h1-3,8-9H,4-7H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233174 (CHEMBL4103892) Show SMILES Fc1c(F)c(F)c(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)c(F)c1F Show InChI InChI=1S/C17H11Cl2F5N2O4S/c18-8-6-9(19)10(31(28,29)26-1-3-30-4-2-26)5-7(8)17(27)25-16-14(23)12(21)11(20)13(22)15(16)24/h5-6H,1-4H2,(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233168 (CHEMBL4085965 | US11124490, Compound 11) Show SMILES Fc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1F Show InChI InChI=1S/C17H13Cl2F3N2O4S/c18-11-8-12(19)15(29(26,27)24-1-3-28-4-2-24)7-10(11)17(25)23-9-5-13(20)16(22)14(21)6-9/h5-8H,1-4H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of ATX (unknown origin) expressed in human A2058 cells assessed as inhibition of LPC-induced cell invasion after 20 hrs by calcein-AM dye ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50233169 (CHEMBL4082022 | US11124490, Compound 3f) Show SMILES Fc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1Cl Show InChI InChI=1S/C17H13Cl3F2N2O4S/c18-11-8-12(19)15(29(26,27)24-1-3-28-4-2-24)7-10(11)17(25)23-9-5-13(21)16(20)14(22)6-9/h5-8H,1-4H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Antagonist activity at LPA1 receptor (unknown origin) expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium level...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 3 (Homo sapiens (Human))	BDBM50056345 (CHEMBL3322500) Show SMILES OC(=O)c1ccccc1SCCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI InChI=1S/C22H17NO4S/c24-20-16-9-3-6-14-7-4-10-17(19(14)16)21(25)23(20)12-5-13-28-18-11-2-1-8-15(18)22(26)27/h1-4,6-11H,5,12-13H2,(H,26,27)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Antagonist activity at human LPA3 expressed in LPA1xLPA2 double knockout mouse MEF cells assessed as reduction in LP18:1-induced calcium mobilization...				J Med Chem 57: 7136-40 (2014) Article DOI: 10.1021/jm5007116 BindingDB Entry DOI: 10.7270/Q22V2HS4
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50233168 (CHEMBL4085965 | US11124490, Compound 11) Show SMILES Fc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1F Show InChI InChI=1S/C17H13Cl2F3N2O4S/c18-11-8-12(19)15(29(26,27)24-1-3-28-4-2-24)7-10(11)17(25)23-9-5-13(20)16(22)14(21)6-9/h5-8H,1-4H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Antagonist activity at LPA1 receptor (unknown origin) expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium level...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50233166 (CHEMBL4060128 | US11124490, Compound 3g) Show SMILES Fc1c(Cl)cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc1Cl Show InChI InChI=1S/C17H13Cl4FN2O4S/c18-11-8-12(19)15(29(26,27)24-1-3-28-4-2-24)7-10(11)17(25)23-9-5-13(20)16(22)14(21)6-9/h5-8H,1-4H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Antagonist activity at LPA1 receptor (unknown origin) expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium level...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50148348 ((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
The University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Agonist activity at human LPA1 expressed in LPA1xLPA2 double knockout mouse MEF cells up to 10 uM by Fura-2AM dye based Ca2+ mobilization assay				J Med Chem 57: 7136-40 (2014) Article DOI: 10.1021/jm5007116 BindingDB Entry DOI: 10.7270/Q22V2HS4
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50233165 (CHEMBL1222042) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OCC(O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Agonist activity at LPA1 receptor (unknown origin) expressed in rat RH7777 cells assessed as increase in intracellular calcium level measured every 3...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 3 (Homo sapiens (Human))	BDBM50233165 (CHEMBL1222042) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OCC(O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Agonist activity at LPA3 receptor (unknown origin) expressed in rat RH7777 cells assessed as increase in intracellular calcium level measured every 3...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50056346 (CHEMBL3322501) Show SMILES OC(=O)c1ccccc1S(=O)(=O)NCCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI InChI=1S/C22H18N2O6S/c25-20-16-9-3-6-14-7-4-10-17(19(14)16)21(26)24(20)13-5-12-23-31(29,30)18-11-2-1-8-15(18)22(27)28/h1-4,6-11,23H,5,12-13H2,(H,27,28)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.16E+3	n/a	n/a	n/a	n/a
The University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Agonist activity at human LPA2 expressed in LPA1xLPA2 double knockout mouse MEF cells by Fura-2AM dye based Ca2+ mobilization assay				J Med Chem 57: 7136-40 (2014) Article DOI: 10.1021/jm5007116 BindingDB Entry DOI: 10.7270/Q22V2HS4
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50056343 (CHEMBL3322513) Show SMILES OC(=O)c1cc(F)ccc1S(=O)(=O)NCCCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI InChI=1S/C23H19FN2O6S/c24-15-9-10-19(18(13-15)23(29)30)33(31,32)25-11-1-2-12-26-21(27)16-7-3-5-14-6-4-8-17(20(14)16)22(26)28/h3-10,13,25H,1-2,11-12H2,(H,29,30)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a	n/a
The University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Agonist activity at human LPA2 expressed in LPA1xLPA2 double knockout mouse MEF cells by Fura-2AM dye based Ca2+ mobilization assay				J Med Chem 57: 7136-40 (2014) Article DOI: 10.1021/jm5007116 BindingDB Entry DOI: 10.7270/Q22V2HS4
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50056347 (CHEMBL3322502) Show SMILES OC(=O)c1ccccc1S(=O)(=O)NCCCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI InChI=1S/C23H20N2O6S/c26-21-17-10-5-7-15-8-6-11-18(20(15)17)22(27)25(21)14-4-3-13-24-32(30,31)19-12-2-1-9-16(19)23(28)29/h1-2,5-12,24H,3-4,13-14H2,(H,28,29)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
The University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Agonist activity at human LPA2 expressed in LPA1xLPA2 double knockout mouse MEF cells by Fura-2AM dye based Ca2+ mobilization assay				J Med Chem 57: 7136-40 (2014) Article DOI: 10.1021/jm5007116 BindingDB Entry DOI: 10.7270/Q22V2HS4
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50056344 (CHEMBL3322514) Show SMILES OC(=O)c1cc(Cl)ccc1S(=O)(=O)NCCCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI InChI=1S/C23H19ClN2O6S/c24-15-9-10-19(18(13-15)23(29)30)33(31,32)25-11-1-2-12-26-21(27)16-7-3-5-14-6-4-8-17(20(14)16)22(26)28/h3-10,13,25H,1-2,11-12H2,(H,29,30)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.00500	n/a	n/a	n/a	n/a
The University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Agonist activity at human LPA2 expressed in LPA1xLPA2 double knockout mouse MEF cells by Fura-2AM dye based Ca2+ mobilization assay				J Med Chem 57: 7136-40 (2014) Article DOI: 10.1021/jm5007116 BindingDB Entry DOI: 10.7270/Q22V2HS4
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50056348 (CHEMBL3322503) Show SMILES OC(=O)c1ccccc1S(=O)(=O)NCCCCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI InChI=1S/C24H22N2O6S/c27-22-18-11-6-8-16-9-7-12-19(21(16)18)23(28)26(22)15-5-1-4-14-25-33(31,32)20-13-3-2-10-17(20)24(29)30/h2-3,6-13,25H,1,4-5,14-15H2,(H,29,30)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a
The University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Agonist activity at human LPA2 expressed in LPA1xLPA2 double knockout mouse MEF cells by Fura-2AM dye based Ca2+ mobilization assay				J Med Chem 57: 7136-40 (2014) Article DOI: 10.1021/jm5007116 BindingDB Entry DOI: 10.7270/Q22V2HS4
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50056349 (CHEMBL3322507) Show SMILES OC(=O)c1ccc(Br)cc1S(=O)(=O)NCCCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI InChI=1S/C23H19BrN2O6S/c24-15-9-10-16(23(29)30)19(13-15)33(31,32)25-11-1-2-12-26-21(27)17-7-3-5-14-6-4-8-18(20(14)17)22(26)28/h3-10,13,25H,1-2,11-12H2,(H,29,30)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
The University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Agonist activity at human LPA2 expressed in LPA1xLPA2 double knockout mouse MEF cells by Fura-2AM dye based Ca2+ mobilization assay				J Med Chem 57: 7136-40 (2014) Article DOI: 10.1021/jm5007116 BindingDB Entry DOI: 10.7270/Q22V2HS4
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50056350 (CHEMBL3322508) Show SMILES OC(=O)c1cc(Br)ccc1S(=O)(=O)NCCCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI InChI=1S/C23H19BrN2O6S/c24-15-9-10-19(18(13-15)23(29)30)33(31,32)25-11-1-2-12-26-21(27)16-7-3-5-14-6-4-8-17(20(14)16)22(26)28/h3-10,13,25H,1-2,11-12H2,(H,29,30)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
The University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Agonist activity at human LPA2 expressed in LPA1xLPA2 double knockout mouse MEF cells by Fura-2AM dye based Ca2+ mobilization assay				J Med Chem 57: 7136-40 (2014) Article DOI: 10.1021/jm5007116 BindingDB Entry DOI: 10.7270/Q22V2HS4
					More data for this Ligand-Target Pair

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