Compile Data Set for Download or QSAR

Found 77 hits with Last Name = 'vousden' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149727 (CHEMBL361420 | {5-[3-(2-Hydroxy-1-phenyl-ethoxy)-4...) Show SMILES OCC(Oc1cc(\C=C2/SC(=S)N(CC(O)=O)C2=O)ccc1OCCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H25NO6S2/c30-18-24(21-9-5-2-6-10-21)35-23-15-20(16-25-27(33)29(17-26(31)32)28(36)37-25)11-12-22(23)34-14-13-19-7-3-1-4-8-19/h1-12,15-16,24,30H,13-14,17-18H2,(H,31,32)/b25-16-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149739 (CHEMBL182293 | {4-Oxo-5-[1-[4-phenethyloxy-3-(1-ph...) Show SMILES CC(Oc1cc(\C=C2/SC(=S)N(CC(O)=O)C2=O)ccc1OCCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H25NO5S2/c1-19(22-10-6-3-7-11-22)34-24-16-21(17-25-27(32)29(18-26(30)31)28(35)36-25)12-13-23(24)33-15-14-20-8-4-2-5-9-20/h2-13,16-17,19H,14-15,18H2,1H3,(H,30,31)/b25-17-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149752 (CHEMBL361718 | {4-Oxo-5-[4-((R)-2-phenyl-butoxy)-3...) Show SMILES CC[C@@H](COc1ccc(\C=C2/SC(=S)N(CC(O)=O)C2=O)cc1O[C@H](c1ccccc1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C30H26F3NO5S2/c1-2-20(21-9-5-3-6-10-21)18-38-23-14-13-19(16-25-28(37)34(17-26(35)36)29(40)41-25)15-24(23)39-27(30(31,32)33)22-11-7-4-8-12-22/h3-16,20,27H,2,17-18H2,1H3,(H,35,36)/b25-16-/t20-,27+/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149777 (CHEMBL366064 | {5-[1-[3-(Carbamoyl-phenyl-methoxy)...) Show SMILES NC(=O)C(Oc1cc(\C=C2/SC(=S)N(CC(O)=O)C2=O)ccc1OCCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H24N2O6S2/c29-26(33)25(20-9-5-2-6-10-20)36-22-15-19(16-23-27(34)30(17-24(31)32)28(37)38-23)11-12-21(22)35-14-13-18-7-3-1-4-8-18/h1-12,15-16,25H,13-14,17H2,(H2,29,33)(H,31,32)/b23-16-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149774 (CHEMBL182467 | {4-Oxo-5-[4-((R)-2-phenyl-propoxy)-...) Show SMILES C[C@@H](COc1ccc(\C=C2/SC(=S)N(CC(O)=O)C2=O)cc1O[C@H](c1ccccc1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C29H24F3NO5S2/c1-18(20-8-4-2-5-9-20)17-37-22-13-12-19(15-24-27(36)33(16-25(34)35)28(39)40-24)14-23(22)38-26(29(30,31)32)21-10-6-3-7-11-21/h2-15,18,26H,16-17H2,1H3,(H,34,35)/b24-15-/t18-,26+/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149764 (CHEMBL185312 | {4-Oxo-5-[3-((S)-1-phenyl-ethoxy)-4...) Show SMILES C[C@@H](COc1ccc(\C=C2/SC(=S)N(CC(O)=O)C2=O)cc1O[C@@H](C)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H27NO5S2/c1-19(22-9-5-3-6-10-22)18-34-24-14-13-21(15-25(24)35-20(2)23-11-7-4-8-12-23)16-26-28(33)30(17-27(31)32)29(36)37-26/h3-16,19-20H,17-18H2,1-2H3,(H,31,32)/b26-16-/t19-,20-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149744 (CHEMBL182588 | {4-Oxo-5-[1-[4-((S)-2-phenyl-butoxy...) Show SMILES CC[C@H](COc1ccc(\C=C2/SC(=S)N(CC(O)=O)C2=O)cc1O[C@H](c1ccccc1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C30H26F3NO5S2/c1-2-20(21-9-5-3-6-10-21)18-38-23-14-13-19(16-25-28(37)34(17-26(35)36)29(40)41-25)15-24(23)39-27(30(31,32)33)22-11-7-4-8-12-22/h3-16,20,27H,2,17-18H2,1H3,(H,35,36)/b25-16-/t20-,27-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149741 (CHEMBL369344 | {4-Oxo-5-[1-[4-((S)-2-phenyl-propox...) Show SMILES C[C@H](COc1ccc(\C=C2/SC(=S)N(CC(O)=O)C2=O)cc1O[C@H](c1ccccc1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C29H24F3NO5S2/c1-18(20-8-4-2-5-9-20)17-37-22-13-12-19(15-24-27(36)33(16-25(34)35)28(39)40-24)14-23(22)38-26(29(30,31)32)21-10-6-3-7-11-21/h2-15,18,26H,16-17H2,1H3,(H,34,35)/b24-15-/t18-,26-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149768 (CHEMBL424794 | {5-[1-[3-(2-Methyl-1-phenyl-propoxy...) Show SMILES CC(C)C(Oc1cc(\C=C2/SC(=S)N(CC(O)=O)C2=O)ccc1OCCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H29NO5S2/c1-20(2)28(23-11-7-4-8-12-23)36-25-17-22(18-26-29(34)31(19-27(32)33)30(37)38-26)13-14-24(25)35-16-15-21-9-5-3-6-10-21/h3-14,17-18,20,28H,15-16,19H2,1-2H3,(H,32,33)/b26-18-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149749 (CHEMBL182291 | {5-[3-(Dipropylcarbamoyl-phenyl-met...) Show SMILES CCCN(CCC)C(=O)C(Oc1cc(\C=C2/SC(=S)N(CC(O)=O)C2=O)ccc1OCCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C34H36N2O6S2/c1-3-18-35(19-4-2)33(40)31(26-13-9-6-10-14-26)42-28-21-25(22-29-32(39)36(23-30(37)38)34(43)44-29)15-16-27(28)41-20-17-24-11-7-5-8-12-24/h5-16,21-22,31H,3-4,17-20,23H2,1-2H3,(H,37,38)/b29-22-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149758 ((5-{3-Benzyloxy-4-[2-(3,5-difluoro-phenyl)-ethoxy]...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCCc3cc(F)cc(F)c3)c(OCc3ccccc3)c2)C1=O Show InChI InChI=1S/C27H21F2NO5S2/c28-20-10-19(11-21(29)14-20)8-9-34-22-7-6-18(12-23(22)35-16-17-4-2-1-3-5-17)13-24-26(33)30(15-25(31)32)27(36)37-24/h1-7,10-14H,8-9,15-16H2,(H,31,32)/b24-13-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149776 (CHEMBL367136 | {4-Oxo-5-[4-phenethyloxy-3-(1-pheny...) Show SMILES CCC(Oc1cc(\C=C2/SC(=S)N(CC(O)=O)C2=O)ccc1OCCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H27NO5S2/c1-2-23(22-11-7-4-8-12-22)35-25-17-21(18-26-28(33)30(19-27(31)32)29(36)37-26)13-14-24(25)34-16-15-20-9-5-3-6-10-20/h3-14,17-18,23H,2,15-16,19H2,1H3,(H,31,32)/b26-18-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149748 (CHEMBL363745 | {5-[3-Benzyloxy-4-(4-chloro-benzylo...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCc3ccc(Cl)cc3)c(OCc3ccccc3)c2)C1=O Show InChI InChI=1S/C26H20ClNO5S2/c27-20-9-6-18(7-10-20)16-32-21-11-8-19(12-22(21)33-15-17-4-2-1-3-5-17)13-23-25(31)28(14-24(29)30)26(34)35-23/h1-13H,14-16H2,(H,29,30)/b23-13-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149737 (CHEMBL360293 | {5-[1-[3-(2-Morpholin-4-yl-2-oxo-1-...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCCc3ccccc3)c(OC(C(=O)N3CCOCC3)c3ccccc3)c2)C1=O Show InChI InChI=1S/C32H30N2O7S2/c35-28(36)21-34-30(37)27(43-32(34)42)20-23-11-12-25(40-16-13-22-7-3-1-4-8-22)26(19-23)41-29(24-9-5-2-6-10-24)31(38)33-14-17-39-18-15-33/h1-12,19-20,29H,13-18,21H2,(H,35,36)/b27-20-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149754 (CHEMBL369715 | {5-[1-{3-Benzyloxy-4-[2-(4-fluoro-p...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCCc3ccc(F)cc3)c(OCc3ccccc3)c2)C1=O Show InChI InChI=1S/C27H22FNO5S2/c28-21-9-6-18(7-10-21)12-13-33-22-11-8-20(14-23(22)34-17-19-4-2-1-3-5-19)15-24-26(32)29(16-25(30)31)27(35)36-24/h1-11,14-15H,12-13,16-17H2,(H,30,31)/b24-15-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149773 ((5-{3-Benzyloxy-4-[2-(4-trifluoromethoxy-phenyl)-e...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCCc3ccc(OC(F)(F)F)cc3)c(OCc3ccccc3)c2)C1=O Show InChI InChI=1S/C28H22F3NO6S2/c29-28(30,31)38-21-9-6-18(7-10-21)12-13-36-22-11-8-20(14-23(22)37-17-19-4-2-1-3-5-19)15-24-26(35)32(16-25(33)34)27(39)40-24/h1-11,14-15H,12-13,16-17H2,(H,33,34)/b24-15-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149735 (CHEMBL181647 | {5-[1-[3-Benzyloxy-4-(3-phenyl-prop...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCCCc3ccccc3)c(OCc3ccccc3)c2)C1=O Show InChI InChI=1S/C28H25NO5S2/c30-26(31)18-29-27(32)25(36-28(29)35)17-22-13-14-23(33-15-7-12-20-8-3-1-4-9-20)24(16-22)34-19-21-10-5-2-6-11-21/h1-6,8-11,13-14,16-17H,7,12,15,18-19H2,(H,30,31)/b25-17-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149766 (CHEMBL369740 | [5-(3-Benzyloxy-4-phenethyloxy-benz...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCCc3ccccc3)c(OCc3ccccc3)c2)C1=O Show InChI InChI=1S/C27H23NO5S2/c29-25(30)17-28-26(31)24(35-27(28)34)16-21-11-12-22(32-14-13-19-7-3-1-4-8-19)23(15-21)33-18-20-9-5-2-6-10-20/h1-12,15-16H,13-14,17-18H2,(H,29,30)/b24-16-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50442784 (CHEMBL2440443) Show SMILES FC(F)(F)c1cccc2cc3c(nc(=O)[nH]c3=O)n(-c3cccc(Cl)c3)c12 Show InChI InChI=1S/C18H9ClF3N3O2/c19-10-4-2-5-11(8-10)25-14-9(3-1-6-13(14)18(20,21)22)7-12-15(25)23-17(27)24-16(12)26/h1-8H,(H,24,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of GST-tagged HDM2 (unknown origin) assessed as p53 ubiquitination by Western blot analysis				Bioorg Med Chem 21: 6868-77 (2013) Article DOI: 10.1016/j.bmc.2013.09.038 BindingDB Entry DOI: 10.7270/Q2KS6T01
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149770 ((5-{3-Benzyloxy-4-[2-(4-chloro-phenyl)-ethoxy]-ben...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCCc3ccc(Cl)cc3)c(OCc3ccccc3)c2)C1=O Show InChI InChI=1S/C27H22ClNO5S2/c28-21-9-6-18(7-10-21)12-13-33-22-11-8-20(14-23(22)34-17-19-4-2-1-3-5-19)15-24-26(32)29(16-25(30)31)27(35)36-24/h1-11,14-15H,12-13,16-17H2,(H,30,31)/b24-15-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149745 (CHEMBL361840 | {5-[3-Benzyloxy-4-((R)-2-phenyl-pro...) Show SMILES C[C@@H](COc1ccc(\C=C2/SC(=S)N(CC(O)=O)C2=O)cc1OCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H25NO5S2/c1-19(22-10-6-3-7-11-22)17-33-23-13-12-21(14-24(23)34-18-20-8-4-2-5-9-20)15-25-27(32)29(16-26(30)31)28(35)36-25/h2-15,19H,16-18H2,1H3,(H,30,31)/b25-15-/t19-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149755 (CHEMBL360588 | {4-Oxo-5-[4-((R)-2-phenyl-propoxy)-...) Show SMILES C[C@@H](COc1ccc(\C=C2/SC(=S)N(CC(O)=O)C2=O)cc1O[C@@H](c1ccccc1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C29H24F3NO5S2/c1-18(20-8-4-2-5-9-20)17-37-22-13-12-19(15-24-27(36)33(16-25(34)35)28(39)40-24)14-23(22)38-26(29(30,31)32)21-10-6-3-7-11-21/h2-15,18,26H,16-17H2,1H3,(H,34,35)/b24-15-/t18-,26-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149756 (CHEMBL426061 | {4-Oxo-5-[1-[3-((R)-1-phenyl-ethoxy...) Show SMILES C[C@@H](COc1ccc(\C=C2/SC(=S)N(CC(O)=O)C2=O)cc1O[C@H](C)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H27NO5S2/c1-19(22-9-5-3-6-10-22)18-34-24-14-13-21(15-25(24)35-20(2)23-11-7-4-8-12-23)16-26-28(33)30(17-27(31)32)29(36)37-26/h3-16,19-20H,17-18H2,1-2H3,(H,31,32)/b26-16-/t19-,20+/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149762 (CHEMBL183715 | {5-[3-Benzyloxy-4-(4-trifluoromethy...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCc3ccc(cc3)C(F)(F)F)c(OCc3ccccc3)c2)C1=O Show InChI InChI=1S/C27H20F3NO5S2/c28-27(29,30)20-9-6-18(7-10-20)16-35-21-11-8-19(12-22(21)36-15-17-4-2-1-3-5-17)13-23-25(34)31(14-24(32)33)26(37)38-23/h1-13H,14-16H2,(H,32,33)/b23-13-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149736 (CHEMBL442034 | {5-[3-Benzyloxy-4-(3-trifluoromethy...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCc3cccc(c3)C(F)(F)F)c(OCc3ccccc3)c2)C1=O Show InChI InChI=1S/C27H20F3NO5S2/c28-27(29,30)20-8-4-7-19(11-20)16-35-21-10-9-18(12-22(21)36-15-17-5-2-1-3-6-17)13-23-25(34)31(14-24(32)33)26(37)38-23/h1-13H,14-16H2,(H,32,33)/b23-13-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149760 (CHEMBL360702 | {5-[3-Benzyloxy-4-(3,4-difluoro-ben...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCc3ccc(F)c(F)c3)c(OCc3ccccc3)c2)C1=O Show InChI InChI=1S/C26H19F2NO5S2/c27-19-8-6-18(10-20(19)28)15-33-21-9-7-17(11-22(21)34-14-16-4-2-1-3-5-16)12-23-25(32)29(13-24(30)31)26(35)36-23/h1-12H,13-15H2,(H,30,31)/b23-12-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149742 (CHEMBL182584 | {5-[1-[4-Benzyloxy-3-(4-trifluorome...) Show SMILES OC(=O)CN1C(=S)S\C(=C\c2ccc(OCc3ccccc3)c(OCc3ccc(OC(F)(F)F)cc3)c2)C1=O Show InChI InChI=1S/C27H20F3NO6S2/c28-27(29,30)37-20-9-6-18(7-10-20)16-36-22-12-19(8-11-21(22)35-15-17-4-2-1-3-5-17)13-23-25(34)31(14-24(32)33)26(38)39-23/h1-13H,14-16H2,(H,32,33)/b23-13+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149771 ((Z)-2-(5-(3,4-bis(benzyloxy)benzylidene)-4-oxo-2-t...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)C1=O Show InChI InChI=1S/C26H21NO5S2/c28-24(29)15-27-25(30)23(34-26(27)33)14-20-11-12-21(31-16-18-7-3-1-4-8-18)22(13-20)32-17-19-9-5-2-6-10-19/h1-14H,15-17H2,(H,28,29)/b23-14-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149757 (CHEMBL182729 | {5-[3-Benzyloxy-4-(4-methyl-benzylo...) Show SMILES Cc1ccc(COc2ccc(\C=C3/SC(=S)N(CC(O)=O)C3=O)cc2OCc2ccccc2)cc1 Show InChI InChI=1S/C27H23NO5S2/c1-18-7-9-20(10-8-18)17-32-22-12-11-21(13-23(22)33-16-19-5-3-2-4-6-19)14-24-26(31)28(15-25(29)30)27(34)35-24/h2-14H,15-17H2,1H3,(H,29,30)/b24-14-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149738 (CHEMBL361337 | {5-[3-Benzyloxy-4-(4-methanesulfony...) Show SMILES CS(=O)(=O)c1ccc(COc2ccc(\C=C3/SC(=S)N(CC(O)=O)C3=O)cc2OCc2ccccc2)cc1 Show InChI InChI=1S/C27H23NO7S3/c1-38(32,33)21-10-7-19(8-11-21)17-34-22-12-9-20(13-23(22)35-16-18-5-3-2-4-6-18)14-24-26(31)28(15-25(29)30)27(36)37-24/h2-14H,15-17H2,1H3,(H,29,30)/b24-14-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149732 (CHEMBL182806 | {5-[3-Benzyloxy-4-(4-methoxy-benzyl...) Show SMILES COc1ccc(COc2ccc(\C=C3/SC(=S)N(CC(O)=O)C3=O)cc2OCc2ccccc2)cc1 Show InChI InChI=1S/C27H23NO6S2/c1-32-21-10-7-19(8-11-21)17-33-22-12-9-20(13-23(22)34-16-18-5-3-2-4-6-18)14-24-26(31)28(15-25(29)30)27(35)36-24/h2-14H,15-17H2,1H3,(H,29,30)/b24-14-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149763 (CHEMBL182172 | {4-Oxo-5-[1-[4-((S)-2-phenyl-propox...) Show SMILES C[C@H](COc1ccc(\C=C2/SC(=S)N(CC(O)=O)C2=O)cc1O[C@@H](c1ccccc1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C29H24F3NO5S2/c1-18(20-8-4-2-5-9-20)17-37-22-13-12-19(15-24-27(36)33(16-25(34)35)28(39)40-24)14-23(22)38-26(29(30,31)32)21-10-6-3-7-11-21/h2-15,18,26H,16-17H2,1H3,(H,34,35)/b24-15-/t18-,26+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149746 (CHEMBL365506 | {5-[1-{3-Benzyloxy-4-[2-(4-trifluor...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCCc3ccc(cc3)C(F)(F)F)c(OCc3ccccc3)c2)C1=O Show InChI InChI=1S/C28H22F3NO5S2/c29-28(30,31)21-9-6-18(7-10-21)12-13-36-22-11-8-20(14-23(22)37-17-19-4-2-1-3-5-19)15-24-26(35)32(16-25(33)34)27(38)39-24/h1-11,14-15H,12-13,16-17H2,(H,33,34)/b24-15-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149767 (CHEMBL181437 | {5-[1-[4-Benzyloxy-3-(3-chloro-benz...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCc3ccccc3)c(OCc3cccc(Cl)c3)c2)C1=O Show InChI InChI=1S/C26H20ClNO5S2/c27-20-8-4-7-19(11-20)16-33-22-12-18(9-10-21(22)32-15-17-5-2-1-3-6-17)13-23-25(31)28(14-24(29)30)26(34)35-23/h1-13H,14-16H2,(H,29,30)/b23-13-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149731 (CHEMBL360107 | {5-[1-{3-Benzyloxy-4-[2-(2,4-difluo...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCCc3ccc(F)cc3F)c(OCc3ccccc3)c2)C1=O Show InChI InChI=1S/C27H21F2NO5S2/c28-20-8-7-19(21(29)14-20)10-11-34-22-9-6-18(12-23(22)35-16-17-4-2-1-3-5-17)13-24-26(33)30(15-25(31)32)27(36)37-24/h1-9,12-14H,10-11,15-16H2,(H,31,32)/b24-13-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149750 (CHEMBL442780 | {5-[1-[4-Benzyloxy-3-(3,4-difluoro-...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCc3ccccc3)c(OCc3ccc(F)c(F)c3)c2)C1=O Show InChI InChI=1S/C26H19F2NO5S2/c27-19-8-6-18(10-20(19)28)15-34-22-11-17(7-9-21(22)33-14-16-4-2-1-3-5-16)12-23-25(32)29(13-24(30)31)26(35)36-23/h1-12H,13-15H2,(H,30,31)/b23-12-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149751 (CHEMBL185129 | {5-[1-[3,4-Bis-(4-fluoro-benzyloxy)...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCc3ccc(F)cc3)c(OCc3ccc(F)cc3)c2)C1=O Show InChI InChI=1S/C26H19F2NO5S2/c27-19-6-1-16(2-7-19)14-33-21-10-5-18(11-22(21)34-15-17-3-8-20(28)9-4-17)12-23-25(32)29(13-24(30)31)26(35)36-23/h1-12H,13-15H2,(H,30,31)/b23-12-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149728 (CHEMBL181903 | {5-[3,4-Bis-(2,4-difluoro-benzyloxy...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCc3ccc(F)cc3F)c(OCc3ccc(F)cc3F)c2)C1=O Show InChI InChI=1S/C26H17F4NO5S2/c27-17-4-2-15(19(29)9-17)12-35-21-6-1-14(8-23-25(34)31(11-24(32)33)26(37)38-23)7-22(21)36-13-16-3-5-18(28)10-20(16)30/h1-10H,11-13H2,(H,32,33)/b23-8-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149772 (CHEMBL182469 | {5-[3-Benzyloxy-4-(2,4-difluoro-ben...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCc3ccc(F)cc3F)c(OCc3ccccc3)c2)C1=O Show InChI InChI=1S/C26H19F2NO5S2/c27-19-8-7-18(20(28)12-19)15-34-21-9-6-17(10-22(21)33-14-16-4-2-1-3-5-16)11-23-25(32)29(13-24(30)31)26(35)36-23/h1-12H,13-15H2,(H,30,31)/b23-11-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149775 (CHEMBL362647 | {5-[1-[4-Benzyloxy-3-(4-chloro-benz...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCc3ccccc3)c(OCc3ccc(Cl)cc3)c2)C1=O Show InChI InChI=1S/C26H20ClNO5S2/c27-20-9-6-18(7-10-20)16-33-22-12-19(8-11-21(22)32-15-17-4-2-1-3-5-17)13-23-25(31)28(14-24(29)30)26(34)35-23/h1-13H,14-16H2,(H,29,30)/b23-13-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149753 (CHEMBL361547 | {5-[4-Benzyloxy-3-(3-methoxy-benzyl...) Show SMILES COc1cccc(COc2cc(\C=C3/SC(=S)N(CC(O)=O)C3=O)ccc2OCc2ccccc2)c1 Show InChI InChI=1S/C27H23NO6S2/c1-32-21-9-5-8-20(12-21)17-34-23-13-19(10-11-22(23)33-16-18-6-3-2-4-7-18)14-24-26(31)28(15-25(29)30)27(35)36-24/h2-14H,15-17H2,1H3,(H,29,30)/b24-14-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50442780 (CHEMBL2443391) Show SMILES Cc1cccc(c1)-n1c2nc(=O)[nH]c(=O)c2cc2cccc(c12)C(F)(F)F Show InChI InChI=1S/C19H12F3N3O2/c1-10-4-2-6-12(8-10)25-15-11(5-3-7-14(15)19(20,21)22)9-13-16(25)23-18(27)24-17(13)26/h2-9H,1H3,(H,24,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of GST-tagged HDM2 (unknown origin) assessed as p53 ubiquitination by Western blot analysis				Bioorg Med Chem 21: 6868-77 (2013) Article DOI: 10.1016/j.bmc.2013.09.038 BindingDB Entry DOI: 10.7270/Q2KS6T01
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149761 (CHEMBL185299 | {5-[1-[4-Benzyloxy-3-(2,4-difluoro-...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCc3ccccc3)c(OCc3ccc(F)cc3F)c2)C1=O Show InChI InChI=1S/C26H19F2NO5S2/c27-19-8-7-18(20(28)12-19)15-34-22-10-17(6-9-21(22)33-14-16-4-2-1-3-5-16)11-23-25(32)29(13-24(30)31)26(35)36-23/h1-12H,13-15H2,(H,30,31)/b23-11-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149740 (CHEMBL369345 | {5-[1-[3-Benzyloxy-4-((S)-2-phenyl-...) Show SMILES C[C@H](COc1ccc(\C=C2/SC(=S)N(CC(O)=O)C2=O)cc1OCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H25NO5S2/c1-19(22-10-6-3-7-11-22)17-33-23-13-12-21(14-24(23)34-18-20-8-4-2-5-9-20)15-25-27(32)29(16-26(30)31)28(35)36-25/h2-15,19H,16-18H2,1H3,(H,30,31)/b25-15-/t19-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50442783 (CHEMBL2440442) Show SMILES FC(F)(F)c1cccc2cc3c(nc(=O)[nH]c3=O)n(-c3ccc(Cl)c(Cl)c3)c12 Show InChI InChI=1S/C18H8Cl2F3N3O2/c19-12-5-4-9(7-13(12)20)26-14-8(2-1-3-11(14)18(21,22)23)6-10-15(26)24-17(28)25-16(10)27/h1-7H,(H,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of GST-tagged HDM2 (unknown origin) assessed as p53 ubiquitination by Western blot analysis				Bioorg Med Chem 21: 6868-77 (2013) Article DOI: 10.1016/j.bmc.2013.09.038 BindingDB Entry DOI: 10.7270/Q2KS6T01
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149747 (CHEMBL185513 | {5-[1-[4-Benzyloxy-3-(3-trifluorome...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCc3ccccc3)c(OCc3cccc(c3)C(F)(F)F)c2)C1=O Show InChI InChI=1S/C27H20F3NO5S2/c28-27(29,30)20-8-4-7-19(11-20)16-36-22-12-18(9-10-21(22)35-15-17-5-2-1-3-6-17)13-23-25(34)31(14-24(32)33)26(37)38-23/h1-13H,14-16H2,(H,32,33)/b23-13-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149729 (CHEMBL182398 | {5-[1-[4-Benzyloxy-3-(4-trifluorome...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCc3ccccc3)c(OCc3ccc(cc3)C(F)(F)F)c2)C1=O Show InChI InChI=1S/C27H20F3NO5S2/c28-27(29,30)20-9-6-18(7-10-20)16-36-22-12-19(8-11-21(22)35-15-17-4-2-1-3-5-17)13-23-25(34)31(14-24(32)33)26(37)38-23/h1-13H,14-16H2,(H,32,33)/b23-13-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50442785 (CHEMBL2440444) Show SMILES FC(F)(F)c1cccc2cc3c(nc(=O)[nH]c3=O)n(-c3ccc(Cl)cc3)c12 Show InChI InChI=1S/C18H9ClF3N3O2/c19-10-4-6-11(7-5-10)25-14-9(2-1-3-13(14)18(20,21)22)8-12-15(25)23-17(27)24-16(12)26/h1-8H,(H,24,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of GST-tagged HDM2 (unknown origin) assessed as p53 ubiquitination by Western blot analysis				Bioorg Med Chem 21: 6868-77 (2013) Article DOI: 10.1016/j.bmc.2013.09.038 BindingDB Entry DOI: 10.7270/Q2KS6T01
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50442782 (CHEMBL2443392) Show SMILES Fc1cccc(c1)-n1c2nc(=O)[nH]c(=O)c2cc2cccc(c12)C(F)(F)F Show InChI InChI=1S/C18H9F4N3O2/c19-10-4-2-5-11(8-10)25-14-9(3-1-6-13(14)18(20,21)22)7-12-15(25)23-17(27)24-16(12)26/h1-8H,(H,24,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of GST-tagged HDM2 (unknown origin) assessed as p53 ubiquitination by Western blot analysis				Bioorg Med Chem 21: 6868-77 (2013) Article DOI: 10.1016/j.bmc.2013.09.038 BindingDB Entry DOI: 10.7270/Q2KS6T01
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50442781 (CHEMBL223723) Show SMILES Fc1ccc(cc1)-n1c2nc(=O)[nH]c(=O)c2cc2cccc(c12)C(F)(F)F Show InChI InChI=1S/C18H9F4N3O2/c19-10-4-6-11(7-5-10)25-14-9(2-1-3-13(14)18(20,21)22)8-12-15(25)23-17(27)24-16(12)26/h1-8H,(H,24,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of GST-tagged HDM2 (unknown origin) assessed as p53 ubiquitination by Western blot analysis				Bioorg Med Chem 21: 6868-77 (2013) Article DOI: 10.1016/j.bmc.2013.09.038 BindingDB Entry DOI: 10.7270/Q2KS6T01
					More data for this Ligand-Target Pair

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