Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50081472 ((2S,3S)-4-(6-Amino-purin-9-yl)-2,3-dihydroxy-butyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Affinity and reactivity of an affinity-labeling reagent, was assessed from the inhibitory constant value | Bioorg Med Chem Lett 9: 2737-40 (1999) BindingDB Entry DOI: 10.7270/Q28C9VFG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085553 (CHEMBL214603 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.720 | n/a | n/a | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease L | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085558 (CHEMBL402676 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'p | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085554 (5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5'...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | MMDB PubMed | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7 | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085556 (CHEMBL405496 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease L | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085555 (CHEMBL384725 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'p | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085559 (CHEMBL410213 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 105 | n/a | n/a | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease L | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085557 (CHEMBL407239 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease L | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085558 (CHEMBL402676 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7 | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085553 (CHEMBL214603 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'p | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085554 (5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5'...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | MMDB PubMed | n/a | n/a | n/a | n/a | 0.150 | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'p | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085559 (CHEMBL410213 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease L | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085556 (CHEMBL405496 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease L | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085559 (CHEMBL410213 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7 | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085554 (5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5'...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | MMDB PubMed | n/a | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7 | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085556 (CHEMBL405496 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 0.680 | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7 | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085557 (CHEMBL407239 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'p | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085558 (CHEMBL402676 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 0.130 | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'p | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085557 (CHEMBL407239 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7 | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085553 (CHEMBL214603 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 0.240 | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'p | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085555 (CHEMBL384725 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7 | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50085555 (CHEMBL384725 | Oligoadenylate analogue) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 0.840 | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease L | Bioorg Med Chem Lett 10: 329-31 (2000) BindingDB Entry DOI: 10.7270/Q2TM79B4 | |||||||||||
More data for this Ligand-Target Pair |