Compile Data Set for Download or QSAR

Found 1001 hits with Last Name = 'yeoh' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589753 (US11559538, Example 16 | US11559538, Example 208 |...) Show SMILES CCCOc1nc(c(F)cc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM139691 (US8895544, 1) Show SMILES CCc1cc(O)c(F)cc1-c1ccc2c(n[nH]c2c1)-c1nc2CN(CCc2[nH]1)C(=O)c1ccc(F)cc1 Show InChI InChI=1S/C28H23F2N5O2/c1-2-15-12-25(36)21(30)13-20(15)17-5-8-19-23(11-17)33-34-26(19)27-31-22-9-10-35(14-24(22)32-27)28(37)16-3-6-18(29)7-4-16/h3-8,11-13,36H,2,9-10,14H2,1H3,(H,31,32)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<0.100	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of GST tagged human recombinant JAK1 catalytic domain expressed in baculovirus using peptide substrate preincubated for 60 mins followed b...				J Med Chem 60: 767-786 (2017) Article DOI: 10.1021/acs.jmedchem.6b01634 BindingDB Entry DOI: 10.7270/Q24J0HDZ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589753 (US11559538, Example 16 | US11559538, Example 208 |...) Show SMILES CCCOc1nc(c(F)cc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589753 (US11559538, Example 16 | US11559538, Example 208 |...) Show SMILES CCCOc1nc(c(F)cc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589895 (US11559538, Example 147 | US11559538, Example 148) Show SMILES CCCOc1cc(ccc1OC)-c1nc(ns1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589886 (US11559538, Example 138 | US11559538, Example 139 ...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589754 (US11559538, Example 17 | US11559538, Example 50) Show SMILES CCCOc1cc(ccc1OC(F)F)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589803 (US11559538, Example 60 | US11559538, Example 61 | ...) Show SMILES CCCOc1nc(ccc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interleukin-4 (Human)	BDBM589948 (US11559538, Example 195 | US11559538, Example 196) Show SMILES CCCOc1cc(ccc1OC)-c1nc(OCCO)cc(n1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589830 (US11559538, Example 84 | US11559538, Example 85) Show SMILES CCCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM139691 (US8895544, 1) Show SMILES CCc1cc(O)c(F)cc1-c1ccc2c(n[nH]c2c1)-c1nc2CN(CCc2[nH]1)C(=O)c1ccc(F)cc1 Show InChI InChI=1S/C28H23F2N5O2/c1-2-15-12-25(36)21(30)13-20(15)17-5-8-19-23(11-17)33-34-26(19)27-31-22-9-10-35(14-24(22)32-27)28(37)16-3-6-18(29)7-4-16/h3-8,11-13,36H,2,9-10,14H2,1H3,(H,31,32)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of GST tagged human recombinant JAK2 catalytic domain expressed in baculovirus using peptide substrate preincubated for 60 mins followed b...				J Med Chem 60: 767-786 (2017) Article DOI: 10.1021/acs.jmedchem.6b01634 BindingDB Entry DOI: 10.7270/Q24J0HDZ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589948 (US11559538, Example 195 | US11559538, Example 196) Show SMILES CCCOc1cc(ccc1OC)-c1nc(OCCO)cc(n1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589803 (US11559538, Example 60 | US11559538, Example 61 | ...) Show SMILES CCCOc1nc(ccc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589948 (US11559538, Example 195 | US11559538, Example 196) Show SMILES CCCOc1cc(ccc1OC)-c1nc(OCCO)cc(n1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589782 (US11559538, Example 42) Show SMILES CCCOc1c(OC)ccc(-c2cccc(c2)C2COB(O)C2)c1C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interleukin-4 (Human)	BDBM589948 (US11559538, Example 195 | US11559538, Example 196) Show SMILES CCCOc1cc(ccc1OC)-c1nc(OCCO)cc(n1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589780 (US11559538, Example 40) Show SMILES COc1ccc(cc1OCCCF)-c1cccc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589886 (US11559538, Example 138 | US11559538, Example 139 ...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50234911 (CHEMBL3928932) Show SMILES CCc1cc(O)ccc1-c1ccc2c(n[nH]c2c1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C22H18N4O/c1-2-13-11-15(27)8-10-16(13)14-7-9-17-20(12-14)25-26-21(17)22-23-18-5-3-4-6-19(18)24-22/h3-12,27H,2H2,1H3,(H,23,24)(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of GST tagged human recombinant JAK1 catalytic domain expressed in baculovirus using peptide substrate preincubated for 60 mins followed b...				J Med Chem 60: 767-786 (2017) Article DOI: 10.1021/acs.jmedchem.6b01634 BindingDB Entry DOI: 10.7270/Q24J0HDZ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589830 (US11559538, Example 84 | US11559538, Example 85) Show SMILES CCCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589895 (US11559538, Example 147 | US11559538, Example 148) Show SMILES CCCOc1cc(ccc1OC)-c1nc(ns1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589754 (US11559538, Example 17 | US11559538, Example 50) Show SMILES CCCOc1cc(ccc1OC(F)F)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589811 (US11559538, Example 68) Show SMILES COc1ccc(cc1OC1CSC1)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589897 (US11559538, Example 149) Show SMILES COc1ccc(cc1OC1CCCC1)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50234908 (CHEMBL4093813) Show SMILES CCc1cc(O)ccc1-c1ccc2c(n[nH]c2c1)-c1nc2CCN(Cc2[nH]1)C(C)=O Show InChI InChI=1S/C23H23N5O2/c1-3-14-10-16(30)5-7-17(14)15-4-6-18-20(11-15)26-27-22(18)23-24-19-8-9-28(13(2)29)12-21(19)25-23/h4-7,10-11,30H,3,8-9,12H2,1-2H3,(H,24,25)(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of GST tagged human recombinant JAK1 catalytic domain expressed in baculovirus using peptide substrate preincubated for 60 mins followed b...				J Med Chem 60: 767-786 (2017) Article DOI: 10.1021/acs.jmedchem.6b01634 BindingDB Entry DOI: 10.7270/Q24J0HDZ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589839 (US11559538, Example 93) Show SMILES COc1cnc(nc1OC1CCCC1)-c1cccc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589740 (US11559538, Example 4) Show SMILES CCCOc1cc(ccc1OC)-c1cncc(c1)[C@@H]1COB(O)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589958 (US11559538, Example 205) Show SMILES CCOc1cc(ccc1OC)-c1c(C)ncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589776 (US11559538, Example 34) Show SMILES CCCOc1cc(ccc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589803 (US11559538, Example 60 | US11559538, Example 61 | ...) Show SMILES CCCOc1nc(ccc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589803 (US11559538, Example 60 | US11559538, Example 61 | ...) Show SMILES CCCOc1nc(ccc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interleukin-4 (Human)	BDBM589753 (US11559538, Example 16 | US11559538, Example 208 |...) Show SMILES CCCOc1nc(c(F)cc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589821 (US11559538, Example 78 | US11559538, Example 79 | ...) Show SMILES COc1ccc(cc1OC1CCSC1)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589825 (US11559538, Example 81 | US11559538, Example 82) Show SMILES CCCOc1c(OC)ccc(c1F)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589830 (US11559538, Example 84 | US11559538, Example 85) Show SMILES CCCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589892 (US11559538, Example 144) Show SMILES CCOc1cc(ccc1SC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.580	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589758 (US11559538, Example 189 | US11559538, Example 21 |...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589856 (US11559538, Example 110) Show SMILES CCCCCOc1cc(ccc1OC)-c1cccc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interleukin-4 (Human)	BDBM589760 (US11559538, Example 124 | US11559538, Example 23 |...) Show SMILES CCCOc1cc(ccc1OC)-c1nc(cc(n1)C(F)(F)F)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589743 (US11559538, Example 193 | US11559538, Example 36 |...) Show SMILES COc1ccc(cc1OC1CC1)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.630	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589758 (US11559538, Example 189 | US11559538, Example 21 |...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.640	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589919 (US11559538, Example 167 | US11559538, Example 168) Show SMILES CCCOc1c(OC)ccc(-c2cncc(c2)C2COB(O)C2)c1OC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.640	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interleukin-4 (Human)	BDBM589754 (US11559538, Example 17 | US11559538, Example 50) Show SMILES CCCOc1cc(ccc1OC(F)F)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589738 (US11559538, Example 2) Show SMILES CCOc1cc(ccc1OC)-c1cncc(c1)[C@H]1COB(O)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589933 (US11559538, Example 181) Show SMILES COc1ccc(cc1OC1CC1)-c1nc(ns1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.680	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589867 (US11559538, Example 121) Show SMILES CCOc1nc(ccc1OC)-c1cccc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589739 (US11559538, Example 3) Show SMILES CCOc1cc(ccc1OC)-c1cncc(c1)[C@@H]1COB(O)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589808 (US11559538, Example 65 | US11559538, Example 66 | ...) Show SMILES COc1ccc(cc1OC1CCCC1)-c1cccc(n1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589743 (US11559538, Example 193 | US11559538, Example 36 |...) Show SMILES COc1ccc(cc1OC1CC1)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589751 (US11559538, Example 15 | US11559538, Example 47) Show SMILES CCOc1cc(c(Cl)cc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 1001 total )  |  Next  |  Last  >>

Jump to: