| Reaction Details |
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 | Report a problem with these data |
| Target | Interleukin-4 |
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| Ligand | BDBM589760 |
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| Substrate/Competitor | n/a |
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| IC50 | 0.610±n/a nM |
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| Citation |  Strohbach, JW; Akama, T; Blakemore, DC; Jacobs, RT; Jones, P; Limburg, DC; Oderinde, MS; Perry, MA; Plattner, JJ; Torella, RF; Zhou, Y; Yeoh, TY Substituted 1,2-oxaborolan-2-ols as PDE4 inhibitors US Patent US11559538 Publication Date 1/24/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Interleukin-4 |
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| Name: | Interleukin-4 |
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| Synonyms: | B-cell stimulatory factor 1 | BSF-1 | Binetrakin | IL-4 | IL4 | IL4_HUMAN | Lymphocyte stimulatory factor 1 | Pitrakinra |
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| Type: | Protein |
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| Mol. Mass.: | 17502.15 |
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| Organism: | Human |
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| Description: | P05112 |
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| Residue: | 153 |
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| Sequence: | MGLTSQLLPPLFFLLACAGNFVHGHKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAAS
KNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGLAGL
NSCPVKEANQSTLENFLERLKTIMREKYSKCSS
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| BDBM589760 |
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| n/a |
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| Name | BDBM589760 |
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| Synonyms: | US11559538, Example 124 | US11559538, Example 23 | US11559538, Example 55 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20BF3N2O4 |
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| Mol. Mass. | 396.169 |
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| SMILES | CCCOc1cc(ccc1OC)-c1nc(cc(n1)C(F)(F)F)C1COB(O)C1 |
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| Structure | 
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