Compile Data Set for Download or QSAR

Found 1064 hits with Last Name = 'akama' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine--tRNA ligase, cytoplasmic (Saccharomyces cerevisiae S288c)	BDBM50370987 (TAVABOROLE) Show SMILES OB1OCc2cc(F)ccc12 Show InChI InChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem	Article PubMed	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Anacor Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase after 20 mins				Science 316: 1759-1761 (2007) Article DOI: 10.1126/science.1142189 BindingDB Entry DOI: 10.7270/Q2P84CQ2
					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Saccharomyces cerevisiae S288c)	BDBM50370987 (TAVABOROLE) Show SMILES OB1OCc2cc(F)ccc12 Show InChI InChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem	Article PubMed	3.14E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Anacor Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase after 2 mins				Science 316: 1759-1761 (2007) Article DOI: 10.1126/science.1142189 BindingDB Entry DOI: 10.7270/Q2P84CQ2
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589753 (US11559538, Example 16 | US11559538, Example 208 |...) Show SMILES CCCOc1nc(c(F)cc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Homo sapiens (Human))	BDBM258601 (US9493490, 6-(4-(aminomethyl)-2-chlorophenoxy)-7-i...) Show SMILES CC(C)c1c2B(O)OCc2ccc1Oc1ccc(CN)cc1Cl Show InChI InChI=1S/C17H19BClNO3/c1-10(2)16-15(6-4-12-9-22-18(21)17(12)16)23-14-5-3-11(8-20)7-13(14)19/h3-7,10,21H,8-9,20H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0550	n/a	n/a	n/a	n/a	n/a	25
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...				US Patent US9493490 (2016) BindingDB Entry DOI: 10.7270/Q2R2109J
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589753 (US11559538, Example 16 | US11559538, Example 208 |...) Show SMILES CCCOc1nc(c(F)cc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-1 (Homo sapiens (Human))	BDBM258601 (US9493490, 6-(4-(aminomethyl)-2-chlorophenoxy)-7-i...) Show SMILES CC(C)c1c2B(O)OCc2ccc1Oc1ccc(CN)cc1Cl Show InChI InChI=1S/C17H19BClNO3/c1-10(2)16-15(6-4-12-9-22-18(21)17(12)16)23-14-5-3-11(8-20)7-13(14)19/h3-7,10,21H,8-9,20H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.195	n/a	n/a	n/a	n/a	n/a	25
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...				US Patent US9493490 (2016) BindingDB Entry DOI: 10.7270/Q2R2109J
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589753 (US11559538, Example 16 | US11559538, Example 208 |...) Show SMILES CCCOc1nc(c(F)cc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589895 (US11559538, Example 147 | US11559538, Example 148) Show SMILES CCCOc1cc(ccc1OC)-c1nc(ns1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589886 (US11559538, Example 138 | US11559538, Example 139 ...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM120866 (US8716478, D253 | US9499570, D253) Show SMILES CC(=O)CCCOc1nc(Oc2ccc3B(O)OCc3c2)c(cc1Cl)C#N Show InChI InChI=1S/C18H16BClN2O5/c1-11(23)3-2-6-25-18-16(20)8-12(9-21)17(22-18)27-14-4-5-15-13(7-14)10-26-19(15)24/h4-5,7-8,24H,2-3,6,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.25	n/a	n/a	n/a	n/a	7.5	n/a
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...				US Patent US9499570 (2016) BindingDB Entry DOI: 10.7270/Q2CZ363N
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM120866 (US8716478, D253 | US9499570, D253) Show SMILES CC(=O)CCCOc1nc(Oc2ccc3B(O)OCc3c2)c(cc1Cl)C#N Show InChI InChI=1S/C18H16BClN2O5/c1-11(23)3-2-6-25-18-16(20)8-12(9-21)17(22-18)27-14-4-5-15-13(7-14)10-26-19(15)24/h4-5,7-8,24H,2-3,6,10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.25	n/a	n/a	n/a	n/a	7.5	37
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...				US Patent US8716478 (2014) BindingDB Entry DOI: 10.7270/Q2Z60MQ7
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589754 (US11559538, Example 17 | US11559538, Example 50) Show SMILES CCCOc1cc(ccc1OC(F)F)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589803 (US11559538, Example 60 | US11559538, Example 61 | ...) Show SMILES CCCOc1nc(ccc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interleukin-4 (Human)	BDBM589948 (US11559538, Example 195 | US11559538, Example 196) Show SMILES CCCOc1cc(ccc1OC)-c1nc(OCCO)cc(n1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589830 (US11559538, Example 84 | US11559538, Example 85) Show SMILES CCCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589948 (US11559538, Example 195 | US11559538, Example 196) Show SMILES CCCOc1cc(ccc1OC)-c1nc(OCCO)cc(n1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589948 (US11559538, Example 195 | US11559538, Example 196) Show SMILES CCCOc1cc(ccc1OC)-c1nc(OCCO)cc(n1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589803 (US11559538, Example 60 | US11559538, Example 61 | ...) Show SMILES CCCOc1nc(ccc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589782 (US11559538, Example 42) Show SMILES CCCOc1c(OC)ccc(-c2cccc(c2)C2COB(O)C2)c1C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interleukin-4 (Human)	BDBM589948 (US11559538, Example 195 | US11559538, Example 196) Show SMILES CCCOc1cc(ccc1OC)-c1nc(OCCO)cc(n1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589780 (US11559538, Example 40) Show SMILES COc1ccc(cc1OCCCF)-c1cccc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589886 (US11559538, Example 138 | US11559538, Example 139 ...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589895 (US11559538, Example 147 | US11559538, Example 148) Show SMILES CCCOc1cc(ccc1OC)-c1nc(ns1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589830 (US11559538, Example 84 | US11559538, Example 85) Show SMILES CCCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589811 (US11559538, Example 68) Show SMILES COc1ccc(cc1OC1CSC1)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589754 (US11559538, Example 17 | US11559538, Example 50) Show SMILES CCCOc1cc(ccc1OC(F)F)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589897 (US11559538, Example 149) Show SMILES COc1ccc(cc1OC1CCCC1)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589740 (US11559538, Example 4) Show SMILES CCCOc1cc(ccc1OC)-c1cncc(c1)[C@@H]1COB(O)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589839 (US11559538, Example 93) Show SMILES COc1cnc(nc1OC1CCCC1)-c1cccc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589958 (US11559538, Example 205) Show SMILES CCOc1cc(ccc1OC)-c1c(C)ncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589776 (US11559538, Example 34) Show SMILES CCCOc1cc(ccc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589803 (US11559538, Example 60 | US11559538, Example 61 | ...) Show SMILES CCCOc1nc(ccc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589803 (US11559538, Example 60 | US11559538, Example 61 | ...) Show SMILES CCCOc1nc(ccc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interleukin-4 (Human)	BDBM589753 (US11559538, Example 16 | US11559538, Example 208 |...) Show SMILES CCCOc1nc(c(F)cc1OC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589821 (US11559538, Example 78 | US11559538, Example 79 | ...) Show SMILES COc1ccc(cc1OC1CCSC1)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589825 (US11559538, Example 81 | US11559538, Example 82) Show SMILES CCCOc1c(OC)ccc(c1F)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589830 (US11559538, Example 84 | US11559538, Example 85) Show SMILES CCCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589892 (US11559538, Example 144) Show SMILES CCOc1cc(ccc1SC)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.580	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589758 (US11559538, Example 189 | US11559538, Example 21 |...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interleukin-4 (Human)	BDBM589760 (US11559538, Example 124 | US11559538, Example 23 |...) Show SMILES CCCOc1cc(ccc1OC)-c1nc(cc(n1)C(F)(F)F)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589856 (US11559538, Example 110) Show SMILES CCCCCOc1cc(ccc1OC)-c1cccc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589743 (US11559538, Example 193 | US11559538, Example 36 |...) Show SMILES COc1ccc(cc1OC1CC1)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.630	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589919 (US11559538, Example 167 | US11559538, Example 168) Show SMILES CCCOc1c(OC)ccc(-c2cncc(c2)C2COB(O)C2)c1OC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.640	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589758 (US11559538, Example 189 | US11559538, Example 21 |...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.640	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interleukin-4 (Human)	BDBM589754 (US11559538, Example 17 | US11559538, Example 50) Show SMILES CCCOc1cc(ccc1OC(F)F)-c1cncc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589738 (US11559538, Example 2) Show SMILES CCOc1cc(ccc1OC)-c1cncc(c1)[C@H]1COB(O)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589933 (US11559538, Example 181) Show SMILES COc1ccc(cc1OC1CC1)-c1nc(ns1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.680	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589867 (US11559538, Example 121) Show SMILES CCOc1nc(ccc1OC)-c1cccc(c1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589739 (US11559538, Example 3) Show SMILES CCOc1cc(ccc1OC)-c1cncc(c1)[C@@H]1COB(O)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589808 (US11559538, Example 65 | US11559538, Example 66 | ...) Show SMILES COc1ccc(cc1OC1CCCC1)-c1cccc(n1)C1COB(O)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
					More data for this Ligand-Target Pair

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