Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50081724 ((4-{5-[1-Aza-bicyclo[2.2.2]oct-(3Z)-ylidenemethyl]...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description The compound was tested for its binding affinity against M1 human recombinant muscarinic receptor in CHO cells. | Bioorg Med Chem Lett 9: 2795-800 (1999) BindingDB Entry DOI: 10.7270/Q26H4GM1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM50081729 (4-{5-[1-Aza-bicyclo[2.2.2]oct-(3Z)-ylidenemethyl]-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description The compound was tested for its binding affinity against nicotinic receptor in synaptic membrane fractions from rat cerebral cortices. | Bioorg Med Chem Lett 9: 2795-800 (1999) BindingDB Entry DOI: 10.7270/Q26H4GM1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM50081733 (3-(3-Methyl-isoxazol-5-ylmethylene)-1-aza-bicyclo[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Compound was tested for its binding affinity against nicotinic receptor in synaptic membrane fractions from rat cerebral cortices. | Bioorg Med Chem Lett 9: 2795-800 (1999) BindingDB Entry DOI: 10.7270/Q26H4GM1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM82070 (CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Compound was tested for its binding affinity against nicotinic receptor in synaptic membrane fractions from rat cerebral cortices. | Bioorg Med Chem Lett 9: 2795-800 (1999) BindingDB Entry DOI: 10.7270/Q26H4GM1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50081734 (3-[1-{3-[3,4-Bis-(4-methoxy-benzyloxy)-phenyl]-iso...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description The compound was tested for its binding affinity against M1 human recombinant muscarinic receptor in CHO cells. | Bioorg Med Chem Lett 9: 2795-800 (1999) BindingDB Entry DOI: 10.7270/Q26H4GM1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM39341 (11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 119 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Compound was tested for its binding affinity against M1 human recombinant muscarinic receptor in CHO cells. | Bioorg Med Chem Lett 9: 2795-800 (1999) BindingDB Entry DOI: 10.7270/Q26H4GM1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50081731 (3-[1-{3-[3,4-Bis-(4-methoxy-benzyloxy)-phenyl]-iso...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 247 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description The compound was tested for its binding affinity against M1 human recombinant muscarinic receptor in CHO cells. | Bioorg Med Chem Lett 9: 2795-800 (1999) BindingDB Entry DOI: 10.7270/Q26H4GM1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50081728 (3-[1-{3-[4-(4-Methoxy-benzyloxy)-phenyl]-isoxazol-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description The compound was tested for its binding affinity against M1 human recombinant muscarinic receptor in CHO cells. | Bioorg Med Chem Lett 9: 2795-800 (1999) BindingDB Entry DOI: 10.7270/Q26H4GM1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50081725 (3-[1-{3-[3,4-Bis-(4-methoxy-benzyloxy)-phenyl]-iso...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description The compound was tested for its binding affinity against M1 human recombinant muscarinic receptor in CHO cells. | Bioorg Med Chem Lett 9: 2795-800 (1999) BindingDB Entry DOI: 10.7270/Q26H4GM1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM50081737 (4-{5-[1-Aza-bicyclo[2.2.2]oct-(3E)-ylidenemethyl]-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 695 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description The compound was tested for its binding affinity against nicotinic receptor in synaptic membrane fractions from rat cerebral cortices. | Bioorg Med Chem Lett 9: 2795-800 (1999) BindingDB Entry DOI: 10.7270/Q26H4GM1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM50081735 (4-{5-[1-Aza-bicyclo[2.2.2]oct-(3E)-ylidenemethyl]-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 803 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description The compound was tested for its binding affinity against nicotinic receptor in synaptic membrane fractions from rat cerebral cortices. | Bioorg Med Chem Lett 9: 2795-800 (1999) BindingDB Entry DOI: 10.7270/Q26H4GM1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50081732 ((4-{5-[1-Aza-bicyclo[2.2.2]oct-(3E)-ylidenemethyl]...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 806 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description The compound was tested for its binding affinity against M1 human recombinant muscarinic receptor in CHO cells. | Bioorg Med Chem Lett 9: 2795-800 (1999) BindingDB Entry DOI: 10.7270/Q26H4GM1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50081736 (3-[1-{3-[4-(4-Methoxy-benzyloxy)-phenyl]-isoxazol-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 809 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description The compound was tested for its binding affinity against M1 human recombinant muscarinic receptor in CHO cells. | Bioorg Med Chem Lett 9: 2795-800 (1999) BindingDB Entry DOI: 10.7270/Q26H4GM1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50081730 (3-[1-{3-[3,4-Bis-(4-methoxy-benzyloxy)-phenyl]-iso...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description The compound was tested for its binding affinity against M1 human recombinant muscarinic receptor in CHO cells. | Bioorg Med Chem Lett 9: 2795-800 (1999) BindingDB Entry DOI: 10.7270/Q26H4GM1 | |||||||||||
More data for this Ligand-Target Pair |