Found 38 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-Pentazocine from human recombinant sigma1 receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting met... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-Pentazocine from human recombinant sigma1 receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting met... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-LSD from human recombinant 5-HT2B receptor stably expressed in HEK cells after 90 mins by microbeta scintillation counting metho... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 575 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-CGP12177 from human recombinant adrenergic Beta2 receptor expressed in Flp-In HEK cells after 90 mins by microbeta scintillation... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [125I]-pindolol from human recombinant adrenergic Beta1 receptor expressed in Flp-In CHO cells after 90 mins by microbeta scintillati... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-Way100635 from human recombinant 5-HT1A expressed in stable CHO cells after 90 mins by microbeta scintillation counting method |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-LSD from human recombinant 5-HT7 receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting method |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-Mesulergine from human recombinant 5-HT2C receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting met... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-N-methylspiperone from human recombinant dopamine D3 receptor expressed in HEKT cells after 90 mins by microbeta scintillation c... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-methylspiperone from human recombinant dopamine D4 receptor expressed in Stable HEK cells after 90 mins by microbeta scintillati... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Histamine H2 receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [125I]-Iodoaminopotentidine from human recombinant histamine H2 receptor expressed in stable HEK cells after 90 mins by microbeta sci... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-QNB/[3H]-NMS from human recombinant Muscarinic acetylcholine M1 receptor expressed in stable CHO cells after 90 mins by microbet... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-QNB/[3H]-NMS from human recombinant Muscarinic acetylcholine M2 receptor expressed in stable CHO cells after 90 mins by microbet... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-DADLE from human recombinant DOR receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting method |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-U69593 from human recombinant KOR receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting metho... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
D(1B) dopamine receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-SCH23390 from human recombinant dopamine D5 receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting m... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M5
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-QNB/[3H]-NMS from human recombinant Muscarinic acetylcholine M5 receptor expressed in stable CHO cells after 90 mins by microbet... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-Pyrilamine from human recombinant histamine H1 receptor expressed in stable HEK cells after 90 mins by microbeta scintillation c... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-QNB/[3H]-NMS from human recombinant Muscarinic acetylcholine M3 receptor expressed in stable CHO cells after 90 mins by microbet... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]5-CT from human recombinant 5-HT1D receptor transiently expressed in HEKT cells after 90 mins by microbeta scintillation counting... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-Prazosin from human recombinant adrenergic alpha1A receptor expressed in cells after 90 mins by microbeta scintillation counting... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
D(1A) dopamine receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-SCH23390 from human recombinant dopamine D1 receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting m... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-Prazosin from human recombinant adrenergic Alpha1B receptor expressed in HEKT cells after 90 mins by microbeta scintillation cou... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]5-CT from human recombinant 5-HT1B receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting metho... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-N-methylspiperone from human recombinant dopamine D2 receptor expressed in stable fibroblast cells after 90 mins by microbeta sc... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-Win35428 from human recombinant DAT receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting met... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-Histamine from human recombinant histamine H4 receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M4
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-QNB/[3H]-NMS from human recombinant Muscarinic acetylcholine M4 receptor expressed in stable CHO cells after 90 mins by microbet... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-DAMGO from human recombinant MOR receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting method |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Alpha-2B adrenergic receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-Rauwolscine from human recombinant adrenergic Alpha2B receptor expressed in HEKT cells after 90 mins by microbeta scintillation ... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-Prazosin from human recombinant adrenergic Alpha1D receptor expressed in cells after 90 mins by microbeta scintillation counting... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-LSD from human recombinant 5-HT6 receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting method |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-GR65630 from human recombinant 5-HT3 receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting method |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1E
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-HT from human recombinant 5-HT1E receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting method |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Sigma intracellular receptor 2
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-Pentazocine from human recombinant sigma2 receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting met... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-CGP12177 from human recombinant adrenergic Beta3 receptor expressed in Flp-In HEK cells after 90 mins by microbeta scintillation... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-Rauwolscine from human recombinant adrenergic Alpha2C receptor expressed in stable MDCK cells after 90 mins by microbeta scintil... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50503049
(CHEMBL4447975)Show SMILES [H][C@@]12CCN[C@]1(C)COc1cc(OC)cc(OC)c21 |r| Show InChI InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Twin Cities
Curated by ChEMBL
| Assay Description Displacement of [3H]-Nisoxetine from human recombinant NET receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting m... |
ACS Med Chem Lett 10: 1436-1442 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00225 BindingDB Entry DOI: 10.7270/Q2DF6VGQ |
More data for this Ligand-Target Pair | |