Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Kynureninase
(Homo sapiens (Human)) | BDBM50288254
(2-ammonio-4-oxo-4-phenyl-(2S)-butanoate | CHEMBL31...)Show InChI InChI=1S/C10H11NO3/c11-8(10(13)14)6-9(12)7-4-2-1-3-5-7/h1-5,8H,6,11H2,(H,13,14)/t8-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
| Article
| 2.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescence |
Bioorg Med Chem Lett 6: 2643-2646 (1996)
Article DOI: 10.1016/S0960-894X(96)00483-0 BindingDB Entry DOI: 10.7270/Q2HM5903 |
More data for this Ligand-Target Pair | |
Polymerase acidic protein
(Hepatitis C virus) | BDBM50288254
(2-ammonio-4-oxo-4-phenyl-(2S)-butanoate | CHEMBL31...)Show InChI InChI=1S/C10H11NO3/c11-8(10(13)14)6-9(12)7-4-2-1-3-5-7/h1-5,8H,6,11H2,(H,13,14)/t8-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
| PubMed
| n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of cap 1 ALMV primed Influenza transcriptase |
Antimicrob Agents Chemother 38: 2827-37 (1995)
BindingDB Entry DOI: 10.7270/Q25H7HBP |
More data for this Ligand-Target Pair | |