Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 224.9 BDBM50350310

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase (Plasmodium falciparum)	BDBM50350310 (CHEMBL1812663) Show SMILES [NH3+]C(CCCCB(O)O)(C(F)F)C([O-])=O Show InChI InChI=1S/C7H14BF2NO4/c9-5(10)7(11,6(12)13)3-1-2-4-8(14)15/h5,14-15H,1-4,11H2,(H,12,13)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drexel University Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum arginase using L-arginine as substrate by colorimetric assay				J Med Chem 54: 5432-43 (2011) Article DOI: 10.1021/jm200443b BindingDB Entry DOI: 10.7270/Q2TH8N21
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50350310 (CHEMBL1812663) Show SMILES [NH3+]C(CCCCB(O)O)(C(F)F)C([O-])=O Show InChI InChI=1S/C7H14BF2NO4/c9-5(10)7(11,6(12)13)3-1-2-4-8(14)15/h5,14-15H,1-4,11H2,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem		n/a	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50350310 (CHEMBL1812663) Show SMILES [NH3+]C(CCCCB(O)O)(C(F)F)C([O-])=O Show InChI InChI=1S/C7H14BF2NO4/c9-5(10)7(11,6(12)13)3-1-2-4-8(14)15/h5,14-15H,1-4,11H2,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a
Drexel University Curated by ChEMBL					Assay Description Binding affinity to human arginase 1 using L-arginine as substrate by surface plasmon resonance assay				J Med Chem 54: 5432-43 (2011) Article DOI: 10.1021/jm200443b BindingDB Entry DOI: 10.7270/Q2TH8N21
					More data for this Ligand-Target Pair