Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 129.0 BDBM92966

Wt: 130.0 BDBM50137860

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxaloacetate decarboxylase (Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)	BDBM92966 (Acetopyruvate) Show SMILES CC(=O)CC(=O)C([O-])=O Show InChI InChI=1S/C5H6O4/c1-3(6)2-4(7)5(8)9/h2H2,1H3,(H,8,9)/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	5.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Biotechnology Institute					Assay Description Competitive inhibition constant determined for PA4872 catalyzed oxaloacetate decarboxylation.				Biochemistry 47: 167-82 (2008) Article DOI: 10.1021/bi701954p BindingDB Entry DOI: 10.7270/Q20V8BDS
					More data for this Ligand-Target Pair
Oxaloacetate decarboxylase (Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)	BDBM92966 (Acetopyruvate) Show SMILES CC(=O)CC(=O)C([O-])=O Show InChI InChI=1S/C5H6O4/c1-3(6)2-4(7)5(8)9/h2H2,1H3,(H,8,9)/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	1.09E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Biotechnology Institute					Assay Description Competitive inhibition constant determined for PA4872 catalyzed oxaloacetate decarboxylation.				Biochemistry 47: 167-82 (2008) Article DOI: 10.1021/bi701954p BindingDB Entry DOI: 10.7270/Q20V8BDS
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50137860 (2,4-dioxopentanoic acid | 2,4-dioxovaleric acid | ...) Show SMILES CC(=O)CC(=O)C(O)=O Show InChI InChI=1S/C5H6O4/c1-3(6)2-4(7)5(8)9/h2H2,1H3,(H,8,9)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Italy. Vinc Curated by ChEMBL					Assay Description Inhibitory activity against Hepatitis C virus RNA dependent RNA polymerase nonstructural protein 5B				J Med Chem 47: 14-7 (2003) Article DOI: 10.1021/jm0342109 BindingDB Entry DOI: 10.7270/Q2736QB8
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50137860 (2,4-dioxopentanoic acid | 2,4-dioxovaleric acid | ...) Show SMILES CC(=O)CC(=O)C(O)=O Show InChI InChI=1S/C5H6O4/c1-3(6)2-4(7)5(8)9/h2H2,1H3,(H,8,9)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.07E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of cap 1 ALMV primed Influenza transcriptase				Antimicrob Agents Chemother 38: 2827-37 (1995) BindingDB Entry DOI: 10.7270/Q25H7HBP
					More data for this Ligand-Target Pair