Found 5 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Arginase
(Plasmodium falciparum) | BDBM50350309
(CHEMBL1812662)Show InChI InChI=1S/C7H16BNO4/c1-7(9,6(10)11)4-2-3-5-8(12)13/h12-13H,2-5,9H2,1H3,(H,10,11) | PDB MMDB
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 2.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Drexel University
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum arginase using L-arginine as substrate by colorimetric assay |
J Med Chem 54: 5432-43 (2011)
Article DOI: 10.1021/jm200443b BindingDB Entry DOI: 10.7270/Q2TH8N21 |
More data for this Ligand-Target Pair | |
Arginase-1
(Homo sapiens (Human)) | BDBM50350309
(CHEMBL1812662)Show InChI InChI=1S/C7H16BNO4/c1-7(9,6(10)11)4-2-3-5-8(12)13/h12-13H,2-5,9H2,1H3,(H,10,11) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery
Curated by ChEMBL
| Assay Description Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay |
Bioorg Med Chem Lett 23: 2027-30 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.024 BindingDB Entry DOI: 10.7270/Q22J6D8K |
More data for this Ligand-Target Pair | |
Arginase-2, mitochondrial
(Homo sapiens (Human)) | BDBM50350309
(CHEMBL1812662)Show InChI InChI=1S/C7H16BNO4/c1-7(9,6(10)11)4-2-3-5-8(12)13/h12-13H,2-5,9H2,1H3,(H,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery
Curated by ChEMBL
| Assay Description Inhibition of human Arg2 by colorimetric assay |
Bioorg Med Chem Lett 23: 2027-30 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.024 BindingDB Entry DOI: 10.7270/Q22J6D8K |
More data for this Ligand-Target Pair | |
Arginase-1
(Homo sapiens (Human)) | BDBM50350309
(CHEMBL1812662)Show InChI InChI=1S/C7H16BNO4/c1-7(9,6(10)11)4-2-3-5-8(12)13/h12-13H,2-5,9H2,1H3,(H,10,11) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a |
Drexel University
Curated by ChEMBL
| Assay Description Binding affinity to human arginase 1 using L-arginine as substrate by surface plasmon resonance assay |
J Med Chem 54: 5432-43 (2011)
Article DOI: 10.1021/jm200443b BindingDB Entry DOI: 10.7270/Q2TH8N21 |
More data for this Ligand-Target Pair | |
Arginase-1
(Homo sapiens (Human)) | BDBM50350309
(CHEMBL1812662)Show InChI InChI=1S/C7H16BNO4/c1-7(9,6(10)11)4-2-3-5-8(12)13/h12-13H,2-5,9H2,1H3,(H,10,11) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| | n/a | n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |