SMILES String Search

Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 291.3
BDBM50448689

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 16 hits in this display
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
DNA polymerase beta (Rattus norvegicus)	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Competitive inhibition of recombinant rat DNA polymerase beta using poly(dA)/oligo(dT)18 as substrate by Lineweaver-Burk plot analysis				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA polymerase beta (Rattus norvegicus)	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.16E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Noncompetitive inhibition of recombinant rat DNA polymerase beta using dTTP as substrate by Lineweaver-Burk plot analysis				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA polymerase beta (Rattus norvegicus)	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of recombinant rat DNA polymerase beta expressed in Escherichia coli JMpbeta5 assessed as inhibition of incorporation of dTTP into poly(dA...				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA polymerase lambda (Mus musculus)	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of mouse DNA polymerase lambda assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
Deoxyribonuclease-1 (Bos taurus)	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of bovine deoxyribonuclease 1 assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
Polynucleotide kinase (Enterobacteria phage T4)	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of T4 bacteriophage polynucleotide kinase assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Mus musculus)	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of mouse IMP dehydrogenase 2 assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
T7 RNA polymerase (Enterobacteria phage T7)	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of T7 RNA polymerase assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA-directed DNA polymerase (Enterobacteria phage T4)	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of T4 bacteriophage DNA polymerase assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA-directed DNA/RNA polymerase mu (Homo sapiens (Human))	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of human His-tagged recombinant DNA polymerase mu expressed in Escherichia coli BL21 assessed as inhibition of incorporation of dTTP into ...				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA polymerase alpha catalytic subunit (Drosophila melanogaster)	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of fruit fly DNA polymerase alpha assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA polymerase kappa (Homo sapiens (Human))	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of C-terminal His-6-tagged human DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into p...				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA polymerase eta (Homo sapiens (Human))	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of C-terminal His-6-tagged human DNA polymerase eta expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into pol...				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA nucleotidylexotransferase (Bos taurus)	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of calf thymus TdT assessed as inhibition of incorporation of dTTP into oligo(dT)18(3'OH) after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA polymerase lambda (Homo sapiens (Human))	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged DNA polymerase lambda expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into p...				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA polymerase delta catalytic subunit (Drosophila melanogaster)	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of fruit fly DNA polymerase delta assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair