Found 22 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis
Curated by ChEMBL
| Assay Description Noncompetitive type inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FR... |
J Med Chem 53: 1056-66 (2010)
Article DOI: 10.1021/jm9012328 BindingDB Entry DOI: 10.7270/Q2BP02VN |
More data for this Ligand-Target Pair | |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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Patents
Similars
| Article PubMed
| n/a | n/a | 442 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute
Curated by ChEMBL
| Assay Description Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrate |
J Med Chem 53: 4958-67 (2010)
Article DOI: 10.1021/jm1005012 BindingDB Entry DOI: 10.7270/Q2G73DXK |
More data for this Ligand-Target Pair | |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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Patents
Similars
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Technical University of Lodz
Curated by ChEMBL
| Assay Description Inhibition of human recombinant autotaxin expressed in insect Sf9 cells using FS-3 as substrate preincubated for 10 mins prior substrate addition mea... |
Bioorg Med Chem Lett 22: 2698-700 (2012)
Article DOI: 10.1016/j.bmcl.2012.03.008 BindingDB Entry DOI: 10.7270/Q27P90DG |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | PDB
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | n/a | n/a | 350 | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center
Curated by ChEMBL
| Assay Description Agonist activity at human LPA1 expressed in LPA1xLPA2 double knockout mouse MEF cells up to 10 uM by Fura-2AM dye based Ca2+ mobilization assay |
J Med Chem 57: 7136-40 (2014)
Article DOI: 10.1021/jm5007116 BindingDB Entry DOI: 10.7270/Q22V2HS4 |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 3
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | UniProtKB/SwissProt
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Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 830 | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center
Curated by ChEMBL
| Assay Description Agonist activity at human LPA3 expressed in LPA1xLPA2 double knockout mouse MEF cells by Fura-2AM dye based Ca2+ mobilization assay |
J Med Chem 57: 7136-40 (2014)
Article DOI: 10.1021/jm5007116 BindingDB Entry DOI: 10.7270/Q22V2HS4 |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 4
(Mus musculus) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 260 | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center
Curated by ChEMBL
| Assay Description Agonist activity at mouse LPA4 expressed in CHO cells by Fura-2AM dye based Ca2+ mobilization assay |
J Med Chem 57: 7136-40 (2014)
Article DOI: 10.1021/jm5007116 BindingDB Entry DOI: 10.7270/Q22V2HS4 |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 5
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | n/a | n/a | 510 | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center
Curated by ChEMBL
| Assay Description Agonist activity at FLAG-tagged human LPA5 expressed in rat B103 cells by Fura-2AM dye based Ca2+ mobilization assay |
J Med Chem 57: 7136-40 (2014)
Article DOI: 10.1021/jm5007116 BindingDB Entry DOI: 10.7270/Q22V2HS4 |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center
Curated by ChEMBL
| Assay Description Agonist activity at human LPA2 expressed in LPA1xLPA2 double knockout mouse MEF cells by Fura-2AM dye based Ca2+ mobilization assay |
J Med Chem 57: 7136-40 (2014)
Article DOI: 10.1021/jm5007116 BindingDB Entry DOI: 10.7270/Q22V2HS4 |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | PDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 31 | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center
Curated by ChEMBL
| Assay Description Agonist activity at LPA1 expressed in human chem1 cells assessed as intracellular calcium mobilization by FLIPR assay |
Bioorg Med Chem 18: 477-95 (2010)
Article DOI: 10.1016/j.bmc.2009.12.020 BindingDB Entry DOI: 10.7270/Q2W66KWQ |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 3
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center
Curated by ChEMBL
| Assay Description Agonist activity at LPA3 expressed in human chem1 cells assessed as intracellular calcium mobilization by FLIPR assay |
Bioorg Med Chem 18: 477-95 (2010)
Article DOI: 10.1016/j.bmc.2009.12.020 BindingDB Entry DOI: 10.7270/Q2W66KWQ |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 5
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center
Curated by ChEMBL
| Assay Description Agonist activity at LPA5 expressed in human chem1 cells assessed as intracellular calcium mobilization by FLIPR assay |
Bioorg Med Chem 18: 477-95 (2010)
Article DOI: 10.1016/j.bmc.2009.12.020 BindingDB Entry DOI: 10.7270/Q2W66KWQ |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | PDB
UniProtKB/SwissProt
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Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description Agonist activity at human LPA1 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 6
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 970 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description Agonist activity at human LPA6 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 5
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | UniProtKB/SwissProt
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Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description Agonist activity at human LPA5 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 4
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 8.10 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 3
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 77 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 29 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description Agonist activity at human LPA2 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | PDB
UniProtKB/SwissProt
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Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 830 | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid
Curated by ChEMBL
| Assay Description Agonist activity at LPA1 receptor (unknown origin) stably expressed in rat RH7777 cells assessed as increase in intracellular calcium level by Fluo-4... |
J Med Chem 63: 2372-2390 (2020)
Article DOI: 10.1021/acs.jmedchem.9b01287 BindingDB Entry DOI: 10.7270/Q2DF6VSR |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | PDB
UniProtKB/SwissProt
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Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a |
Oxford University
Curated by ChEMBL
| Assay Description Agonistic activity against lysophosphatidic acid receptor 1 using [35S]-GTP-gammaS as radioligand tested in vitro |
Bioorg Med Chem Lett 14: 3473-6 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.061 BindingDB Entry DOI: 10.7270/Q2D50MDW |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 3
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | UniProtKB/SwissProt
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CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 263 | n/a | n/a | n/a | n/a |
Oxford University
Curated by ChEMBL
| Assay Description Agonistic activity against lysophosphatidic acid receptor 3 using [35S]-GTP-gammaS as radioligand tested in vitro |
Bioorg Med Chem Lett 14: 3473-6 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.061 BindingDB Entry DOI: 10.7270/Q2D50MDW |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid
Curated by ChEMBL
| Assay Description Binding affinity to LPA1 receptor (unknown origin) by cell-based backscattering interferometry |
J Med Chem 63: 2372-2390 (2020)
Article DOI: 10.1021/acs.jmedchem.9b01287 BindingDB Entry DOI: 10.7270/Q2DF6VSR |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148348
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 6.80 | n/a | n/a | n/a | n/a |
Oxford University
Curated by ChEMBL
| Assay Description Agonistic activity against lysophosphatidic acid receptor 2 using [35S]-GTP-gammaS as radioligand tested in vitro |
Bioorg Med Chem Lett 14: 3473-6 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.061 BindingDB Entry DOI: 10.7270/Q2D50MDW |
More data for this Ligand-Target Pair | |