Found 6 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Lysophosphatidic acid receptor 6
(Homo sapiens (Human)) | BDBM50430007
(CHEMBL2335051)Show SMILES CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)([O-])=S Show InChI InChI=1S/C22H45O6PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(23)28-21(19-26-2)20-27-29(24,25)30/h21H,3-20H2,1-2H3,(H2,24,25,30)/p-1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 76 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description
Agonist activity at human LPA6 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 5
(Homo sapiens (Human)) | BDBM50430007
(CHEMBL2335051)Show SMILES CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)([O-])=S Show InChI InChI=1S/C22H45O6PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(23)28-21(19-26-2)20-27-29(24,25)30/h21H,3-20H2,1-2H3,(H2,24,25,30)/p-1 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description
Agonist activity at human LPA5 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM50430007
(CHEMBL2335051)Show SMILES CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)([O-])=S Show InChI InChI=1S/C22H45O6PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(23)28-21(19-26-2)20-27-29(24,25)30/h21H,3-20H2,1-2H3,(H2,24,25,30)/p-1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description
Agonist activity at human LPA1 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 3
(Homo sapiens (Human)) | BDBM50430007
(CHEMBL2335051)Show SMILES CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)([O-])=S Show InChI InChI=1S/C22H45O6PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(23)28-21(19-26-2)20-27-29(24,25)30/h21H,3-20H2,1-2H3,(H2,24,25,30)/p-1 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description
Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50430007
(CHEMBL2335051)Show SMILES CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)([O-])=S Show InChI InChI=1S/C22H45O6PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(23)28-21(19-26-2)20-27-29(24,25)30/h21H,3-20H2,1-2H3,(H2,24,25,30)/p-1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 146 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description
Agonist activity at human LPA2 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 4
(Homo sapiens (Human)) | BDBM50430007
(CHEMBL2335051)Show SMILES CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)([O-])=S Show InChI InChI=1S/C22H45O6PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(23)28-21(19-26-2)20-27-29(24,25)30/h21H,3-20H2,1-2H3,(H2,24,25,30)/p-1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description
Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this
Ligand-Target Pair | |