Found 13 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
D(2) dopamine receptor
(Rattus norvegicus (rat)) | BDBM50284797
(7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxo...)Show InChI InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 83 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Valencia
Curated by ChEMBL
| Assay Description
Displacement of [3H]-raclopride from D2 receptor of Wistar rat striatal membranes after 1 hr by liquid scintillation counting |
Bioorg Med Chem Lett 23: 4824-7 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.078
BindingDB Entry DOI: 10.7270/Q2BK1G9S |
More data for this
Ligand-Target Pair | |
D(2) dopamine receptor
(Rattus norvegicus (rat)) | BDBM50284797
(7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxo...)Show InChI InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 84 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Valencia
Curated by ChEMBL
| Assay Description
Displacement of [3H]-raclopride from D2 receptor of Wistar rat striatal membranes after 1 hr by liquid scintillation counting |
Bioorg Med Chem Lett 23: 4824-7 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.078
BindingDB Entry DOI: 10.7270/Q2BK1G9S |
More data for this
Ligand-Target Pair | |
D(1A) dopamine receptor
(RAT) | BDBM50284797
(7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxo...)Show InChI InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 324 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Valencia
Curated by ChEMBL
| Assay Description
Displacement of [3H]-SCH23390 from D1 receptor of Wistar rat striatal membranes after 1 hr by liquid scintillation counting |
Bioorg Med Chem Lett 23: 4824-7 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.078
BindingDB Entry DOI: 10.7270/Q2BK1G9S |
More data for this
Ligand-Target Pair | |
D(1A) dopamine receptor
(RAT) | BDBM50284797
(7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxo...)Show InChI InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 324 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Valencia
Curated by ChEMBL
| Assay Description
Displacement of [3H]-SCH23390 from D1 receptor of Wistar rat striatal membranes after 1 hr by liquid scintillation counting |
Bioorg Med Chem Lett 23: 4824-7 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.078
BindingDB Entry DOI: 10.7270/Q2BK1G9S |
More data for this
Ligand-Target Pair | |
Caspase-9
(Homo sapiens (Human)) | BDBM50284797
(7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxo...)Show InChI InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| PCBioAssay
| n/a | n/a | 2.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
| Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q25M647F |
More data for this
Ligand-Target Pair | |
Methyl-CpG-binding domain protein 2
(Homo sapiens (Human)) | BDBM50284797
(7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxo...)Show InChI InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| PCBioAssay
| n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide... |
PubChem Bioassay (2013)
BindingDB Entry DOI: 10.7270/Q20K2778 |
More data for this
Ligand-Target Pair | |
Apoptotic protease-activating factor 1
(Homo sapiens (Human)) | BDBM50284797
(7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxo...)Show InChI InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| PCBioAssay
| n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
| Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q2JS9NZB |
More data for this
Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50284797
(7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxo...)Show InChI InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50306886
(CHEMBL602275 | Roemerine-HBr)Show InChI InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3/t14-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of CDK2 |
Bioorg Med Chem Lett 20: 1384-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.007
BindingDB Entry DOI: 10.7270/Q2QF8TTB |
More data for this
Ligand-Target Pair | |
Apoptotic protease-activating factor 1
(Homo sapiens (Human)) | BDBM50284797
(7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxo...)Show InChI InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| PCBioAssay
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
| Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q2F18X8S |
More data for this
Ligand-Target Pair | |
Protein tyrosine phosphatase receptor type C-associated protein
(Homo sapiens (Human)) | BDBM50284797
(7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxo...)Show InChI InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 1.07E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory activity against recombinant CD45 protein tyrosine phosphatase |
Bioorg Med Chem Lett 5: 1519-1522 (1995)
Article DOI: 10.1016/0960-894X(95)00250-W
BindingDB Entry DOI: 10.7270/Q2V69K2S |
More data for this
Ligand-Target Pair | |
POsterior Segregation
(Caenorhabditis elegans) | BDBM50284797
(7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxo...)Show InChI InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3 | PDB
KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 1.68E+4 | n/a | n/a | n/a | n/a |
Broad Institute
Curated by PubChem BioAssay
| Assay Description
Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q28G8J4C |
More data for this
Ligand-Target Pair | |
Zinc finger protein mex-5
(Caenorhabditis elegans) | BDBM50284797
(7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxo...)Show InChI InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 2.15E+4 | n/a | n/a | n/a | n/a |
Broad Institute
Curated by PubChem BioAssay
| Assay Description
Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2D798VP |
More data for this
Ligand-Target Pair | |