Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM173467
(US9096606, 4)Show SMILES CO[C@]12CC[C@@]3(C[C@@H]1COCc1ccc(F)cc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CC[N]1(C)CC1CC1)c45 |r,TLB:8:7:28.27:3.4| Show InChI InChI=1S/C32H39FNO4/c1-34(17-20-3-4-20)14-13-31-27-22-7-10-25(35)28(27)38-29(31)32(36-2)12-11-30(31,26(34)15-22)16-23(32)19-37-18-21-5-8-24(33)9-6-21/h5-10,20,23,26,29,35H,3-4,11-19H2,1-2H3/t23-,26-,29-,30-,31+,32-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| 0.260 | -50.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Purdue Pharma, L.P.
US Patent
| Assay Description
Membranes from recombinant HEK-293 cells expressing the human kippa opioid receptor (cloned in house) were prepared by lysing cells in ice cold hypot... |
US Patent US9096606 (2015)
BindingDB Entry DOI: 10.7270/Q2J101XF |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM173467
(US9096606, 4)Show SMILES CO[C@]12CC[C@@]3(C[C@@H]1COCc1ccc(F)cc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CC[N]1(C)CC1CC1)c45 |r,TLB:8:7:28.27:3.4| Show InChI InChI=1S/C32H39FNO4/c1-34(17-20-3-4-20)14-13-31-27-22-7-10-25(35)28(27)38-29(31)32(36-2)12-11-30(31,26(34)15-22)16-23(32)19-37-18-21-5-8-24(33)9-6-21/h5-10,20,23,26,29,35H,3-4,11-19H2,1-2H3/t23-,26-,29-,30-,31+,32-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 9.55 | -49.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 50 |
Purdue Pharma, L.P.
US Patent
| Assay Description
Radioligand dose-displacement binding assays for -opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane ... |
US Patent US9096606 (2015)
BindingDB Entry DOI: 10.7270/Q2J101XF |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM173467
(US9096606, 4)Show SMILES CO[C@]12CC[C@@]3(C[C@@H]1COCc1ccc(F)cc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CC[N]1(C)CC1CC1)c45 |r,TLB:8:7:28.27:3.4| Show InChI InChI=1S/C32H39FNO4/c1-34(17-20-3-4-20)14-13-31-27-22-7-10-25(35)28(27)38-29(31)32(36-2)12-11-30(31,26(34)15-22)16-23(32)19-37-18-21-5-8-24(33)9-6-21/h5-10,20,23,26,29,35H,3-4,11-19H2,1-2H3/t23-,26-,29-,30-,31+,32-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 175 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P.
US Patent
| Assay Description
δ-opioid Receptor Binding Assay Procedures were conducted as follows. Radioligand dose-displacement assays used 0.3 nM [3H]-Naltrindole (Perkin ... |
US Patent US9096606 (2015)
BindingDB Entry DOI: 10.7270/Q2J101XF |
More data for this
Ligand-Target Pair | |
Opioid growth factor receptor-like protein 1
(Homo sapiens (Human)) | BDBM173467
(US9096606, 4)Show SMILES CO[C@]12CC[C@@]3(C[C@@H]1COCc1ccc(F)cc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CC[N]1(C)CC1CC1)c45 |r,TLB:8:7:28.27:3.4| Show InChI InChI=1S/C32H39FNO4/c1-34(17-20-3-4-20)14-13-31-27-22-7-10-25(35)28(27)38-29(31)32(36-2)12-11-30(31,26(34)15-22)16-23(32)19-37-18-21-5-8-24(33)9-6-21/h5-10,20,23,26,29,35H,3-4,11-19H2,1-2H3/t23-,26-,29-,30-,31+,32-/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| >2.00E+4 | >-24.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Purdue Pharma, L.P.
US Patent
| Assay Description
Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Perkin Elmer, Shelton, Conn.) were prepared by l... |
US Patent US9096606 (2015)
BindingDB Entry DOI: 10.7270/Q2J101XF |
More data for this
Ligand-Target Pair | |