Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity protein kinase CLK2
(Homo sapiens (Human)) | BDBM317481
(4-(4-cyclobutoxy-5-(2- methylbenzo[d]oxazol-6-yl)-...)Show SMILES COc1cc(ccc1Nc1nc(OC2CCC2)c2c(c[nH]c2n1)-c1ccc2nc(C)oc2c1)C(=O)NC1COC1 Show InChI InChI=1S/C29H28N6O5/c1-15-31-22-8-6-16(10-24(22)39-15)20-12-30-26-25(20)28(40-19-4-3-5-19)35-29(34-26)33-21-9-7-17(11-23(21)37-2)27(36)32-18-13-38-14-18/h6-12,18-19H,3-5,13-14H2,1-2H3,(H,32,36)(H2,30,33,34,35) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 5.92 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase TTK
(Homo sapiens (Human)) | BDBM317481
(4-(4-cyclobutoxy-5-(2- methylbenzo[d]oxazol-6-yl)-...)Show SMILES COc1cc(ccc1Nc1nc(OC2CCC2)c2c(c[nH]c2n1)-c1ccc2nc(C)oc2c1)C(=O)NC1COC1 Show InChI InChI=1S/C29H28N6O5/c1-15-31-22-8-6-16(10-24(22)39-15)20-12-30-26-25(20)28(40-19-4-3-5-19)35-29(34-26)33-21-9-7-17(11-23(21)37-2)27(36)32-18-13-38-14-18/h6-12,18-19H,3-5,13-14H2,1-2H3,(H,32,36)(H2,30,33,34,35) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM317481
(4-(4-cyclobutoxy-5-(2- methylbenzo[d]oxazol-6-yl)-...)Show SMILES COc1cc(ccc1Nc1nc(OC2CCC2)c2c(c[nH]c2n1)-c1ccc2nc(C)oc2c1)C(=O)NC1COC1 Show InChI InChI=1S/C29H28N6O5/c1-15-31-22-8-6-16(10-24(22)39-15)20-12-30-26-25(20)28(40-19-4-3-5-19)35-29(34-26)33-21-9-7-17(11-23(21)37-2)27(36)32-18-13-38-14-18/h6-12,18-19H,3-5,13-14H2,1-2H3,(H,32,36)(H2,30,33,34,35) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 526 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |