Found 21 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description In vitro binding affinity towards cloned human 5-HT1B receptor using [3H]5-carboximidotryptamine as radioligand |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 103 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Affinity towards cloned human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 315 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Affinity towards cloned human 5-hydroxytryptamine 1A receptor |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 841 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description In vitro binding affinity towards cloned human 5-HT6 receptor using [3H]5-carboximidotryptamine as radioligand |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description In vitro binding affinity towards cloned human 5-HT2C receptor using [3H]5-carboximidotryptamine as radioligand |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Affinity towards cloned Dopamine receptor D2 |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M5
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Affinity towards cloned Muscarinic acetylcholine receptor M5 |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Affinity towards cloned Muscarinic acetylcholine receptor M1 |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Affinity towards cloned Muscarinic acetylcholine receptor M3 |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Affinity towards cloned Histamine H1 receptor |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M4
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Affinity towards cloned Muscarinic acetylcholine receptor M4 |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
D(1B) dopamine receptor
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Affinity towards cloned Dopamine receptor D5 |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Affinity towards cloned Opioid receptor delta 1 |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Affinity towards cloned Dopamine receptor D3 |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Affinity towards cloned Muscarinic acetylcholine receptor M2 |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Affinity towards cloned Opioid receptor mu 1 |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Affinity towards cloned Opioid receptor kappa 1 |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description In vitro binding affinity towards cloned human 5-HT2A receptor using [3H]5-carboximidotryptamine as radioligand |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Affinity towards cloned Dopamine receptor D4 |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description In vitro binding affinity towards cloned human 5-HT7 receptor using [3H]5-carboximidotryptamine as radioligand |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |
D(1A) dopamine receptor
(Homo sapiens (Human)) | BDBM50173092
(4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [...)Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2F)cc1N1CCN(C)CC1 Show InChI InChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-18(7-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-4-3-5-19(20)24/h3-8,17H,9-16H2,1-2H3,(H,25,30) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Affinity towards cloned Dopamine receptor D1 |
Bioorg Med Chem Lett 15: 4786-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ |
More data for this Ligand-Target Pair | |