Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM251723
(US10100018, Example 59 | US9464060, 59)Show SMILES COc1cccc(CN(Cc2ccc(C(O)=O)c(F)c2)C(=O)c2ccc(Oc3ccccc3F)cc2)c1 Show InChI InChI=1S/C29H23F2NO5/c1-36-23-6-4-5-19(15-23)17-32(18-20-9-14-24(29(34)35)26(31)16-20)28(33)21-10-12-22(13-11-21)37-27-8-3-2-7-25(27)30/h2-16H,17-18H2,1H3,(H,34,35) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | 25 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i... |
US Patent US10100018 (2018)
BindingDB Entry DOI: 10.7270/Q2PR7Z0N |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 5
(Homo sapiens (Human)) | BDBM251723
(US10100018, Example 59 | US9464060, 59)Show SMILES COc1cccc(CN(Cc2ccc(C(O)=O)c(F)c2)C(=O)c2ccc(Oc3ccccc3F)cc2)c1 Show InChI InChI=1S/C29H23F2NO5/c1-36-23-6-4-5-19(15-23)17-32(18-20-9-14-24(29(34)35)26(31)16-20)28(33)21-10-12-22(13-11-21)37-27-8-3-2-7-25(27)30/h2-16H,17-18H2,1H3,(H,34,35) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | 37 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Engagement of the LPA5 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ... |
US Patent US9464060 (2016)
BindingDB Entry DOI: 10.7270/Q23R0RT0 |
More data for this Ligand-Target Pair | |